γ-linolenic and stearidonic acids from Boraginaceae of diverse Mediterranean origin.
Abstract Thirty Boraginaceae species from different tribes were evaluated in a search of γ-linolenic (GLA, 18:3 n- 6)- and stearidonic acid (SDA, 18:4 n- 3)-rich oils. The higher GLA percentages were found in the seed oils of Symphytum bulbosum and S. tuberosum subsp. tuberosum (27.6 and 27.2% of total fatty acids (FA)), which are unusual values for GLA-oils in the current literature. On the whole seed, noticeable GLA percentages were found in S. grandiflorum , S. tuberosum subsp. tuberosum and Borago officinalis (7.43, 4.90, and 4.51 g /100 g, respectively). The main SDA-taxa detected in this study were ...
Source: Chemistry and Biodiversity - October 12, 2020 Category: Biochemistry Authors: Guil Guerrero JL, González-Fernández MJ, Lyashenko S, Fabrikov D, Rincón-Cervera MÁ, Gómez-Mercado F, Urrestarazu M Tags: Chem Biodivers Source Type: research

Fabric Selection in Atopic Dermatitis: An Evidence-Based Review
ConclusionsAppropriate fabric selection can reduce the symptom severity and exacerbations of atopic dermatitis. (Source: American Journal of Clinical Dermatology)
Source: American Journal of Clinical Dermatology - May 20, 2020 Category: Dermatology Source Type: research

Prospective clinical trial examining the impact of genetic variation in FADS1 on the metabolism of linoleic acid- and ɣ-linolenic acid-containing botanical oils.
CONCLUSIONS: The results of this study clearly suggest that personalized and population-based approaches considering FADS genetic variation may be necessary to optimize the design of future clinical studies with GLA-containing oils. This trial was registered at clinicaltrials.gov as NCT02337231. PMID: 32167131 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - March 12, 2020 Category: Nutrition Authors: Sergeant S, Hallmark B, Mathias RA, Mustin TL, Ivester P, Bohannon ML, Ruczinski I, Johnstone L, Seeds MC, Chilton FH Tags: Am J Clin Nutr Source Type: research

Role of peppermint oil in improving the oxidative stability and antioxidant capacity of borage seed oil-loaded nanoemulsions fabricated by modified starch.
Abstract Borage seed oil (BSO) is one of the richest sources of ??-linolenic acid and linoleic acid, which are considered to retain plenty of health promoting benefits. However, its application in functional foods and dietary supplements remains limited owing to its superior vulnerability to oxidation. To solve this problem, ultrasound-assisted BSO-loaded nanoemulsions were prepared with modified starch incorporating different concentrations of peppermint oil (PO), as a natural antioxidant. The influence of different PO levels on the mean droplet size, rheology attributes, and oxidative stability of nanoem...
Source: International Journal of Biological Macromolecules - February 25, 2020 Category: Biochemistry Authors: Rehman A, Jafari SM, Tong Q, Karim A, Mahdi AA, Iqbal MW, Aadil RM, Ali A, Manzoor MF Tags: Int J Biol Macromol Source Type: research

A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale).
CONCLUSION: These cases are an unreliable body of evidence on which to draw conclusions about oral consumption of Symphytum officinale and Tussilago farfara. With insufficient evidence to differentiate the relative risk of one PA-containing plant from another; toxicological studies based on oral ingestion of phytochemically complex preparations of these herbs may be the most accurate methodology for assessing clinical risk. PMID: 32105669 [PubMed - as supplied by publisher] (Source: Fitoterapia)
Source: Fitoterapia - February 23, 2020 Category: Biochemistry Authors: Avila C, Breakspear I, Hawrelak J, Salmond S, Evans S Tags: Fitoterapia Source Type: research

Borage, camellia, centaurea and pansies: nutritional, fatty acids, free sugars, vitamin E, carotenoids and organic acids characterization
Publication date: Available online 4 February 2020Source: Food Research InternationalAuthor(s): Luana Fernandes, Elsa Ramalhosa, José Alberto Pereira, Jorge Alexandre Saraiva, Susana CasalAbstractThe present study aimed to evaluate the nutritional and bioactive potential of four edible flowers (borage, centaurea, camellia, and pansies). Significant differences were observed among the four. Water was the main constituent (>76%, fresh weight - fw). Linoleic and palmitic acids were the major fatty acids found in borage and red and yellow pansies, while in camellia it was the arachidic acid. In white pansies, behenic and arac...
Source: Food Research International - February 7, 2020 Category: Food Science Source Type: research

Improvement of thermal stability and antioxidant activity of anthocyanins of Echium amoenum petal using maltodextrin/modified starch combination as wall material.
Abstract To protect anthocyanins of Iranian borage extract (IBE) by encapsulation, maltodextrin (MD)/modified maize starch (MMS) combinations were used at four ratios (MD/MMS: 1/0, 1/0.25, 1/0.5, 1/1, w/w%). The microencapsulated powders with different ratios of wall material presented encapsulation efficacy between 93.1 and 97.4%. FTIR confirmed the cross-linking interaction between extract and MD/MMS wall. Increased thermal stability of extract was also indicated by DSC analysis. The stability of microstructures and crude extract at two conditions (5 and 40 °C) was evaluated by UV and HPLC methods dur...
Source: International Journal of Biological Macromolecules - January 20, 2020 Category: Biochemistry Authors: Mehran M, Masoum S, Memarzadeh M Tags: Int J Biol Macromol Source Type: research

Independent evolution of rosmarinic acid biosynthesis in two sister families under the Lamiids clade of flowering plants [Metabolism]
As a means to maintain their sessile lifestyle amid challenging environments, plants produce an enormous diversity of compounds as chemical defenses against biotic and abiotic insults. The underpinning metabolic pathways that support the biosynthesis of these specialized chemicals in divergent plant species provide a rich arena for understanding the molecular evolution of complex metabolic traits. Rosmarinic acid (RA) is a phenolic natural product first discovered in plants of the mint family (Lamiaceae) and is recognized for its wide range of medicinal properties and potential applications in human dietary and medical int...
Source: Journal of Biological Chemistry - October 17, 2019 Category: Chemistry Authors: Olesya Levsh, Tomaš Pluskal, Valentina Carballo, Andrew J. Mitchell, Jing–Ke Weng Tags: Plant Biology Source Type: research

The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis.
Conclusion: Feeding FO-enriched diet prevented age-related bone and HBM loss, by reducing MAT expansion. Our results further emphasize on the role(s) of MAT expansion in bone and HBM atrophy.Methods: SAMP8 mice (n>9 /group) were allocated into 4 categories and fed a control ration, FO-, sunflower oil (SFO)- and borage oil-enriched diets for lifetime. Femurs were scanned using microcomputed tomography (μCT) and bone, MAT, and HBM volumes were determined using an image analysis software. PMID: 31553309 [PubMed - as supplied by publisher] (Source: Aging)
Source: Aging - September 24, 2019 Category: Biomedical Science Authors: Bani Hassan E, Alderghaffar M, Wauquier F, Coxam V, Demontiero O, Vogrin S, Wittrant Y, Duque G Tags: Aging (Albany NY) Source Type: research

Borage oil: tocopherols, sterols and squalene in farmed and endemic-wild Borago species
Publication date: Available online 15 August 2019Source: Journal of Food Composition and AnalysisAuthor(s): Dmitri Fabrikov, José Luis Guil-Guerrero, María José González-Fernández, Ignacio Rodríguez-García, Francisco Gómez-Mercado, Miguel Urrestarazu, María Teresa Lao, Miguel Ángel Rincón-Cervera, Juan E. Álvaro, Svetlana LyashenkoAbstractEndemic Borago species contain notably high amounts of γ-linolenic acid (GLA, 18:3n6), the main bioactive fatty acid of borage oil. However, little is known about the occurrence of nutritionally relevant phytochemicals in seed oil of such plants. This work was designed to tes...
Source: Journal of Food Composition and Analysis - August 16, 2019 Category: Food Science Source Type: research

Attraction of green lacewings (Neuroptera: Chrysopidae) to native plants used as ground cover in woody Mediterranean agroecosystems
Publication date: Available online 8 August 2019Source: Biological ControlAuthor(s): Rafael Alcalá Herrera, Francisca Ruano, Cándido Gálvez Ramírez, Stephanie Frischie, Mercedes CamposAbstractUsing native seeds to establish semi-natural habitats is a novel strategy to restore biodiversity and ecosystem services such as biological control. As green lacewings (Neuroptera: Chrysopidae) are regarded as major biological control agents in different crops, the objective of this study was to test the attractiveness of selected native plant species to lacewings. During a two-year (2016-2017) field experiment near Villarrubia (A...
Source: Biological Control - August 8, 2019 Category: Biology Source Type: research

The Effect of Borage (Echium amoenum) on the Mouse Heart and Hematology Parameters
(Source: Cardiovascular and Haematological Disorders - Drug Targets)
Source: Cardiovascular and Haematological Disorders - Drug Targets - July 13, 2019 Category: Cardiology Authors: Sadighara, Parisa Araghi, Atefeh Tajdar-oranj, Behrouz Roudsari, Leila P. Mohajer, Afsaneh Behzadi, Ramezan Tags: Research article Source Type: research

Lipid emulsions for parenterally fed preterm infants.
CONCLUSIONS: In the current review, we did not find any particular LE with or without fish oil to be better than another LE in preterm infants for prevention of PNALD/cholestasis, growth, mortality, ROP, BPD and other neonatal outcomes.In preterm infants with surgical conditions or cholestasis, there is currently insufficient evidence from randomised studies to determine with any certainty if fish oil LEs offer advantage in prevention or resolution of cholestasis or in any other clinical outcome.Further research, with larger well-designed trials, is warranted to evaluate the ideal composition of LE in preterm infants and t...
Source: Cochrane Database of Systematic Reviews - June 3, 2019 Category: General Medicine Authors: Kapoor V, Malviya MN, Soll R Tags: Cochrane Database Syst Rev Source Type: research

Lipid emulsions for parenterally fed term and late preterm infants.
CONCLUSIONS: Based on the current review, there is insufficient data from randomised studies to determine with any certainty, the potential benefit of any LE including fish oil-containing LEs over another LE, for prevention or resolution of PNALD/cholestasis or any other outcomes in term and late preterm infants with underlying surgical conditions or cholestasis. There were no studies in infants without surgical conditions or cholestasis.Further research is required to establish role of fish oil or lipids from other sources in LEs to improve PNALD/cholestasis, and other clinical outcomes in parenterally fed term and late p...
Source: Cochrane Database of Systematic Reviews - June 3, 2019 Category: General Medicine Authors: Kapoor V, Malviya MN, Soll R Tags: Cochrane Database Syst Rev Source Type: research

Phytochemical characterization of Borago officinalis L. and Centaurea cyanus L. during flower development phytochemical profiles of borage and centaurea
Publication date: Available online 10 May 2019Source: Food Research InternationalAuthor(s): L. Fernandes, J.A. Pereira, J.A. Saraiva, E. Ramalhosa, S. CasalAbstractThe present work details the nutritional and chemical compositions of borage and centaurea, at three flowering stages. Water was the main constituent, followed by total dietary fiber. Both flowers showed statistically different (p < .05) nutritional and chemical profiles, although in both, polyunsaturated fatty acids (PUFAs) (mainly linoleic and α-linolenic acids), free sugars (3.9–28.9% dw as fructose, glucose, and sucrose), tocopherols (with the maj...
Source: Food Research International - May 12, 2019 Category: Food Science Source Type: research