Molecules, Vol. 28, Pages 868: Phenolic Profile and Comparison of the Antioxidant, Anti-Ageing, Anti-Inflammatory, and Protective Activities of Borago officinalis Extracts on Skin Cells
In this study, methanol and water–methanol extracts of borage (Borago officinalis) herb dried using various methods were analysed for their phenolic profile and biological activity. Twelve compounds, including flavonoids (astragalin, kaempferol 4-glucoside, rutoside, and vitexin) and phenolic acids (caffeic, chlorogenic, 3,4-dihydroxyphenylacetic, ferulic, p-hydroxybenzoic, protocatechuic, rosmarinic, and syringic), were determined qualitatively and quantitatively in B. officinalis extracts by the HPLC-DAD method. The highest total flavonoid content was confirmed for the methanol extract from the hot-air-drie...
Source: Molecules - January 15, 2023 Category: Chemistry Authors: Monika Michalak Martyna Zag órska-Dziok Marta Klimek-Szczykutowicz Agnieszka Szopa Tags: Article Source Type: research

Molecules, Vol. 27, Pages 3190: Statistical FT-IR Spectroscopy for the Characterization of 17 Vegetable Oils
č Vegetable oils have been utilized for centuries in the food, cosmetic, and pharmaceutical industries, and they contribute beneficially to overall human health, to active skincare, and to effective treatments. Monitoring of the vegetable oils is carried out by the methods described in the European Pharmacopeia, which is time-consuming, has poor repeatability, and involves the use of toxic organic chemicals and expensive laboratory equipment. Many successful studies using IR spectroscopy have been carried out for the detection of geographical origin and adulteration as well as quantification of oxidation parameters. T...
Source: Molecules - May 17, 2022 Category: Chemistry Authors: Meta Kokalj Ladan Nina Ko čevar Glavač Tags: Article Source Type: research

Vegetable Butters and Oils as Therapeutically and Cosmetically Active Ingredients for Dermal Use: A Review of Clinical Studies
While the chemical composition of vegetable butters and oils has been studied in detail, there is limited knowledge about their mechanisms of action after application on the skin. To understand their dermal effects better, 27 clinical studies evaluating 17 vegetable oils (almond, argan, avocado, borage, coconut, evening primrose, kukui, marula, mustard, neem, olive, rapeseed, sacha inchi, safflower, shea butter, soybean and sunflower oils) were reviewed in this research. The reviewed studies focused on non-affected skin, infant skin, psoriasis, xerosis, UVB-induced erythema, atopic dermatitis, molluscum contagiosum, tungia...
Source: Frontiers in Pharmacology - April 25, 2022 Category: Drugs & Pharmacology Source Type: research

Genes, Vol. 13, Pages 243: First Glimpse on Spring Starflower Domestication
ojsgaard The cultivation and domestication of plants are human-driven processes that change the biology and attributes of a plant. Ipheion uniflorum is a bulbous geophyte known as Spring Starflower whose cultivation dates back to the first half of the 19th century. At least seven cultivars have been developed from natural stands. However, comparative analyses of wild and cultivated materials are largely missing. In the present study, we provide a morphological evaluation and analyses of the cytological and genetic variability of I. uniflorum that reveal significant levels of differentiation and evidence of artificial s...
Source: Genes - January 27, 2022 Category: Genetics & Stem Cells Authors: Sassone Blattner Giussani Hojsgaard Tags: Brief Report Source Type: research

Molecules, Vol. 27, Pages 134: Extraction of Anthocyanins from Borage (Echium amoenum) Flowers Using Choline Chloride and a Glycerol-Based, Deep Eutectic Solvent: Optimization, Antioxidant Activity, and In Vitro Bioavailability
lkay Koca Borage flower (Echium amoenum), an annual herb native to the Mediterranean region, is an excellent source of anthocyanins and is widely used in various forms due to its biological activities. In the present study, a choline chloride and glycerol (CHGLY)-based natural deep eutectic solvent (NADES) was applied in order to extract the anthocyanins from borage flowers. The traditional solvents, including water, methanol, and ethanol, were used to evaluate the efficiency of CHGLY. The results showed that CHGLY was highly efficient compared to the traditional solvents, providing the highest amounts of the total ant...
Source: Molecules - December 27, 2021 Category: Chemistry Authors: Oscar Zannou Hojjat Pashazadeh Mohamed Ghellam Salam A. Ibrahim Ilkay Koca Tags: Article Source Type: research

The effect of Borago officinalis on the signaling pathway of the NLRP3 inflammasome complex, TLR4 and some inflammatory cytokines in type II diabetic patients with acute respiratory distress syndrome
Cell Mol Biol (Noisy-le-grand). 2021 Nov 25;67(3):178-183. doi: 10.14715/cmb/2021.67.3.28.ABSTRACTAcute respiratory distress syndrome (ARDS) is a life-threatening condition in which the lungs become severely inflamed, causing the alveoli to constrict or fill with fluid, which prevents the lungs from functioning properly. This disease becomes more dangerous when it occurs in patients with diabetes. Because of the clinical condition of these patients, it is not possible to treat them with usual medicines. One of the best options for treating these people is to use herbs. Borage (Borago officinalis) is a medicinal herb that, ...
Source: Cellular and Molecular Biology - December 22, 2021 Category: Molecular Biology Authors: Yanqiu Yue Fengbin Jin Xiaohui Yue Source Type: research