Pyrrolizidine alkaloids in borage (Borago officinalis): Comprehensive profiling and development of a validated LC-MS/MS method for quantification
Talanta. 2023 Mar 7;258:124425. doi: 10.1016/j.talanta.2023.124425. Online ahead of print.ABSTRACTPyrrolizidine alkaloids (PA) from borage (Borago officinalis) consumed as herb and tea, may pose a food safety risk. Therefore, the European Union (EU) set maximum levels of PA in borage, among other foodstuffs, which are applicable since July 1st, 2022. Here, a comprehensive LC-MS/MS based profiling of PA and their N-oxides (PANO) in B. officinalis leaves is presented. Based on these results a targeted, quantitative LC-MS/MS method for the determination of individual PA/PANO present in borage was developed. Chromatographic se...
Source: Talanta - March 16, 2023 Category: Chemistry Authors: Melinda Sattler Volker M üller Diana Bunzel Sabine E Kulling Sebastian T Soukup Source Type: research

Pyrrolizidine alkaloids in borage (Borago officinalis): Comprehensive profiling and development of a validated LC-MS/MS method for quantification
Talanta. 2023 Mar 7;258:124425. doi: 10.1016/j.talanta.2023.124425. Online ahead of print.ABSTRACTPyrrolizidine alkaloids (PA) from borage (Borago officinalis) consumed as herb and tea, may pose a food safety risk. Therefore, the European Union (EU) set maximum levels of PA in borage, among other foodstuffs, which are applicable since July 1st, 2022. Here, a comprehensive LC-MS/MS based profiling of PA and their N-oxides (PANO) in B. officinalis leaves is presented. Based on these results a targeted, quantitative LC-MS/MS method for the determination of individual PA/PANO present in borage was developed. Chromatographic se...
Source: Talanta - March 16, 2023 Category: Chemistry Authors: Melinda Sattler Volker M üller Diana Bunzel Sabine E Kulling Sebastian T Soukup Source Type: research

GC/MS Profiling and Evaluation of Leaf Essential Oil for Bactericidal Effect and Free Radical Scavenging Activity of Plectranthus amboinicus (Lour.)Spreng Collected from Odisha, India
The objective of the present work is to evaluate the free radical scavenging activity and bactericidal effect of leaf essential oil (EO) of Plectranthus amboinicus (Lour.) Spreng collected from the state of Odisha, India. The hydro distillation technique has been used for essential oil extraction. Upon GC/MS analysis, approximately 57 compounds were identified with Carvacrol as the major compound (peak area=20.25%), followed by p-thymol (peak area= 20.17%), o-cymene (peak area=19.41%) and carene (peak area= 15.89%). On evaluation of free radical scavenging activity, it was recorded that the best value of inhibitory concent...
Source: Chemistry and Biodiversity - January 24, 2023 Category: Biochemistry Authors: Biswajit Jena Bhagyashree Biswal Ashirbad Sarangi Alok Kumar Giri Debapriya Bhattacharya Laxmikanta Acharya Source Type: research

GC/MS Profiling and Evaluation of Leaf Essential Oil for Bactericidal Effect and Free Radical Scavenging Activity of Plectranthus amboinicus (Lour.)Spreng Collected from Odisha, India
The objective of the present work is to evaluate the free radical scavenging activity and bactericidal effect of leaf essential oil (EO) of Plectranthus amboinicus (Lour.) Spreng collected from the state of Odisha, India. The hydro distillation technique has been used for essential oil extraction. Upon GC/MS analysis, approximately 57 compounds were identified with Carvacrol as the major compound (peak area=20.25%), followed by p-thymol (peak area= 20.17%), o-cymene (peak area=19.41%) and carene (peak area= 15.89%). On evaluation of free radical scavenging activity, it was recorded that the best value of inhibitory concent...
Source: Chemistry and Biodiversity - January 24, 2023 Category: Biochemistry Authors: Biswajit Jena Bhagyashree Biswal Ashirbad Sarangi Alok Kumar Giri Debapriya Bhattacharya Laxmikanta Acharya Source Type: research