Dr. Dan Brat interviewed on Northwestern Feinberg School of Medicine Podcast
In the latest episode of theNorthwestern Medicine Breakthroughs podcast,Daniel Brat, MD, PhD discusses the emerging integrated molecular-histomorphological classification of diffuse gliomas. In an episode entitled " A New Way to Diagnose Brain Tumors " , Dr. Brat -- the new chairman of theNorthwestern Pathology -- states that "whenever you go through a reclassification that dramatic, there ' s going to be gaps in knowledge and gaps in practice and we are recognizing those gaps on aDr. Dan Bratdaily basis, on a yearly basis.  And we as a brain tumor community internationally are working to fill those gaps in knowledge....
Source: neuropathology blog - May 25, 2018 Category: Radiology Tags: neuropathologists Source Type: blogs

Best Post of April 2018: Exuberant endothelial reactive hyperplasia next to a subacute infarct biopsied to rule out neoplasia
The next is on " Best of the Month " series is from Tuesday, April 3, 2018:Endothelial hyperplasia next to an infarct, not to be confused with microvascular proliferation in a glioma (Source: neuropathology blog)
Source: neuropathology blog - May 24, 2018 Category: Radiology Tags: Best of the Month series vascular disease Source Type: blogs

The " specific glioneuronal element " of dysembryoplastic neuroepithelial tumor
A " floating neuron " is circled in this " glioneuronal element " of a DNTA pathognomonic feature of dysembrioplastic neuroepithelial tumors (DNTs) is the " specific glioneuronal element " which consists of oligodendroglial-like cells lined up on either side of a paucicellular and mucinous region in which lone neurons appear to float. (Source: neuropathology blog)
Source: neuropathology blog - May 22, 2018 Category: Radiology Tags: neoplasms Source Type: blogs

Astroblastoma
This is a rare, as yet ungraded, cerebral tumor of childhood. It is composed of cells that are GFAP positive and have broad, non-tapering processes radiating toward central blood vessels (astroblastic pseudorosettes). The border with adjacent brain is pushing, not infiltrative. Hyalinized vessels (as seen below) are a hallmark of astroblastoma. No ependymal features have been identified in studies of this unusual entity. (Source: neuropathology blog)
Source: neuropathology blog - May 17, 2018 Category: Radiology Tags: neoplasms Source Type: blogs

Age of First Football Tackles Tied to Neurobehavioral Symptom Onset
Younger age of exposure to tackle football predicts earlier neurobehavioral symptom onset among players with chronic traumatic encephalopathy (CTE), according to a study recently published online in the Annals of Neurology.Michael L. Alosco, Ph.D., from Boston University, and colleagues examined the brains of 246 tackle football players donated for neuropathological examination. Of the 211 who were diagnosed with CTE, 126 were without comorbid neurodegenerative diseases. Age of first exposure and age of cognitive and behavioral/mood symptom onset were determined through informant interviews. (Source: neuropathology blog)
Source: neuropathology blog - May 16, 2018 Category: Radiology Tags: trauma Source Type: blogs

Understanding Neurophobia Among Medical and Other Health Care Students
Andre Toulouse, PhD, (University College,Cork, Ireland) lead author onarticle about neurophobiaNeurophobia, a trepidation among students in health-related fields when it comes to neuroanatomy, is a real thing and has been studied by several researchers in medical education. A recent paper by an Irish group appearing in Anatomical Sciences Education, entitled " Understanding neurophobia: reasons behind impaired understanding and learning of neuroanatomy in cross-disciplinary healthcare students " , examines this phenomenon further. The authors write: "Neuroanatomy is perceived as a more difficult subject compared ...
Source: neuropathology blog - May 14, 2018 Category: Radiology Tags: anatomy websites Source Type: blogs

Best Post of March 2018 - Featured Neuropathologist: Michael Punsoni, MD
The next in our " Best of the Month " series is from March 12, 2018On occasion, we profile a prominent or rising neuropathologist. In the past, we ' ve featured the likes of Craig Horbinski, Roger McLendon, Jan Leestma, and Karra Jones. Today we feature Michael Punsoni, MD, a 2016 graduate of the Brown University Neuropathology Fellowship Program and now on faculty at the University of Nebraska in Omaha. Dr. Punsoni agreed to engage in a little Q&A:1. Why did you decide to become a neuropathologist?I have always had a strong interest in science and medicine, particularly the neurosciences....
Source: neuropathology blog - May 10, 2018 Category: Radiology Tags: Best of the Month series neuropathologists Source Type: blogs

The American Association of Neuropathologists Awarded R13 Conference Grant by National Institute on Aging
The American Association of Neuropathologists (AANP) today announced that it has been awarded an R13 Support for Conferences and Scientific Meetings grant through the National Institute on Aging of the National Institutes of Health. This grant will support the 94th Annual Meeting of the AANP in Louisville, KY.Dr. Edward Lee“We are extremely pleased to be recipients of an R13 grant to support dissemination of the critical work completed by our members and featured by our annual meeting,” said Assistant Secretary Treasurer/Chair of the Education Committee,Edward Lee, MD, PhD. “The National Plan to Address Alzheimer’s...
Source: neuropathology blog - May 7, 2018 Category: Radiology Tags: meetings Source Type: blogs

Dr. R. Ross Reichard and Dr. Daniel J. Brat will be giving the What Every Neuropathologist Needs to Know lectures at upcoming annual AANP meeting
The 94thAnnual Meeting of the American Association of Neuropathologists will take place June 7-10 in Louisville, Kentucky. On June 9th, Dr. R. Ross Reichard and Dr. Daniel J. Brat who will be giving theWhat Every Neuropathologist Needs to Know lectures. Dr. Reichard will discuss ways a neuropathologist may be involved in legal proceedings. Dr. Brat will talk about the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy - Not Official WHO (cIMPACT-NOW), an initiative to address grading challenges in CNS tumors given new findings regarding the impact of molecular signatures on prognosis. (Sourc...
Source: neuropathology blog - May 4, 2018 Category: Radiology Tags: neoplasms neuropathologists Source Type: blogs

Dr. R. Ross Reichard and Dr. Daniel J. Brat who will be giving the What Every Neuropathologist Needs to Know lectures at upcoming annual AANP meeting
The 94thAnnual Meeting of the American Association of Neuropathologists will take place June 7-10 in Louisville, Kentucky. On June 9th, Dr. R. Ross Reichard and Dr. Daniel J. Brat who will be giving theWhat Every Neuropathologist Needs to Know lectures. Dr. Reichard will discuss ways a neuropathologist may be involved in legal proceedings. Dr. Brat will talk about the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy - Not Official WHO (cIMPACT-NOW), an initiative to address grading challenges in CNS tumors given new findings regarding the impact of molecular signatures on prognosis. (Sourc...
Source: neuropathology blog - May 4, 2018 Category: Radiology Tags: neoplasms neuropathologists Source Type: blogs

Pilomyxoid astrocytoma
Angiocentricity, a hallmark of pilomyxoid astroctyoma, is demonstrated hereAlthough thought to be related to pilocytic astrocytoma, full characterization of pilomyxoid astrocytoma has yet to yield a definitive WHO grade for these tumors (although the prior edition of the WHO book pegged this tumor as grade II). Pilomyxoid astrocytomas differ from pilocytic astrocytomas in that they tend not to be biphasic or harbor Rosenthal fibers. (Source: neuropathology blog)
Source: neuropathology blog - May 2, 2018 Category: Radiology Tags: neoplasms Source Type: blogs

Best Post of February 2018: Tau accumulations in the brains of woodpeckers
The next in our " Best of the Month " series comes from February 21, 2018Dr. Peter Cummings makes another appearance on the blog, this time as senior author on a paper entitled: Tau Accumulations in the Brains of Woodpeckers. Eight of ten woodpeckers examined showed cerebral tau accumulations, whereas no control brains (red-winged blackbirds) were positive.This is significant in that there has been some research interest in developing football helmets based on the protective design that has evolved to protect the brains of woodpeckers.But maybe the relatively short life of the woodpecker (average less than 10 yea...
Source: neuropathology blog - April 30, 2018 Category: Radiology Tags: Best of the Month series trauma Source Type: blogs

Ann McKee named to Time Magazine's Annual List of the 100 Most Influential People in the World
Ann McKee, MDDr. Ann McKee joins Rihanna, Donald Trump, and Oprah Winfrey on the list of Time Magazines ' s annual list of the100 most influential people in the world for 2018. The full list appears in the April 30 issue of Time Magazine. McKee is the chief of neuropathology at the VA Boston Healthcare System and director of the Boston University Chronic Traumatic Encephalopathy (CTE) Center.McKee ' s research focuses on the long-term effects of concussion, subconcussion and blast injury in contact sports athletes and military veterans, including CTE. Her work has shifted the prevailing paradigm of scientific thought regar...
Source: neuropathology blog - April 26, 2018 Category: Radiology Tags: neuropathologists trauma Source Type: blogs

YouTube has lecture by Dr. Arie Perry entitled " Approach to Diagnosis of Glial Neoplasms "
Looking for a good overview of glial neoplasms? There ' s a lecture on YouTube entitled Approach to Diagnosis of Glial Neoplasms by Dr. Arie Perry. Check it out!Screenshot of Dr. Perry ' s Lecture on YouTube (Source: neuropathology blog)
Source: neuropathology blog - April 24, 2018 Category: Radiology Tags: neuropathologists Source Type: blogs

Chordoid Glioma, WHO grade II in a 63-year-old male presenting with disequilibrium and hypothermia
(Source: neuropathology blog)
Source: neuropathology blog - April 18, 2018 Category: Radiology Tags: neoplasms Source Type: blogs