Best Post of January 2017: Corneal ulceration secondary to Candidal keratitis
The next in our " Best of the Month " Series is from January 20, 2017. A good photomicrograph is worth a thousand words.GMS stain highlights fungal forms in the corneal stroma (Source: neuropathology blog)
Source: neuropathology blog - May 16, 2017 Category: Radiology Tags: Best of the Month series ophthalmic pathology Source Type: blogs
Registration still open for annual meeting of the American Association of Neuropathologists
https://aanp.memberclicks.net/2017_AANP_Annual_Meeting_FINAL#/ (Source: neuropathology blog)
Source: neuropathology blog - May 12, 2017 Category: Radiology Tags: meetings Source Type: blogs
Diagnostic Slide Session cases have been released by AANP
The American Association of Neuropathologists has released the cases for the2017 Diagnostic Slide Session, which will be held at the association ' sannual meeting on Saturday, June 10 from 8 to 11 pm. The session, which will be moderated by Drs. Caterina Giannini Rebecca D. Folkerth, focuses on a discussion of 10 cases submitted by members far and wide. (Source: neuropathology blog)
Source: neuropathology blog - May 3, 2017 Category: Radiology Tags: meetings Source Type: blogs
Best Post of December 2016: Fibrous Bodies Nicely Demonstrated in a Smear from a Somatotroph Pituitary Adenoma
The next in our " Best of the Month Series " is from December 2, 2016:Christian Davidson, MDDr. Christian Davidson, director of neuropathology at the Robert Wood Johnson University Hospitalin New Jersey, provides today ' s blog post:A 30-year-old man presented with bitemporal hemianopsia and a 3.0 cm pituitary mass was discovered upon MRI. His IGF-1 was elevated to 900, but he had no signs of acromegaly. A smear of tissue sent for frozen section evaluation (see below) revealed that most cells had round, eosinophilic, perinuclear inclusions suggestive of fibrous bodies (some examples are circled). Dot-like CAM5.2 ...
Source: neuropathology blog - April 25, 2017 Category: Radiology Tags: Best of the Month series neoplasms pituitary Source Type: blogs
Screenshots of the surgical neuropathology volume of the Johns Hopkins Atlases of Pathology
A month ago Iput up a post regarding the release of Volume 3 of the Johns Hopkins Atlases of Pathology for the iPad. This app only costs $4.99 . Here are some screenshots of the app provided to me by series editorToby Cornish, MD, PhD: (Source: neuropathology blog)
Source: neuropathology blog - April 6, 2017 Category: Radiology Tags: apps Source Type: blogs
This slow growing " pineal mass " was thought by radiologists to be a pineocytoma
Not definitively attached to the dura, but the neuroradiologist wisely put meningioma on the differential diagnosis. Microscopy showed WHO grade I meningioma. (Source: neuropathology blog)
Source: neuropathology blog - March 24, 2017 Category: Radiology Tags: neoplasms Source Type: blogs
An update on SF-1 driven pituitary adenomas
Adenomas driven by the transcription factor SF-1, which are exclusively gonadotroph adenomas, are a common subtype encountered by the surgical pathologist. Traditionally, gonadotroph adenomas have been defined by positive immunostaining for luteinizing hormone (LH) and/or follicle stimulating hormone (FSH) with or without alpha-subunit ( αSU). However, evidence is now emerging that replacement of these three immunostains by the single SF-1 stain results in a more cost-effective and sensitive means of detecting gonadotrophin adenomas. Further, the majority of previously classified " null cell " adenomas -- negative for all...
Source: neuropathology blog - March 22, 2017 Category: Radiology Tags: pituitary Source Type: blogs
" Gross only " sign out of intraocular lens prosthesis
When signing out our gross only IOL cases, my ophthalmologists want me to comment as to whether the " haptics " are completely present to confirm that nothing has been inadvertently left behind in the patient. If you are wondering what a " haptic " is, it the curving blue filament that emerges from the prosthetic lens serving to keep the lens in place. The term " haptic " means " related to the sense of touch " ; but I am not sure why this term is used in this context. Perhaps a reader knows?IOL with blue haptics in place (Source: neuropathology blog)
Source: neuropathology blog - March 21, 2017 Category: Radiology Tags: ophthalmic pathology Source Type: blogs
Retinal biopsy from an elderly woman with suspected ocular lymphoma
The patient had multiple foci of markedly thickened retina on exam. Ophthomologists were able to obtain a relatively large retinal biopsy. We did not find lymphoma in this case, and infections of many sorts were ruled out. But the ophthalmologists wanted an opinion as to whether retinal vasculitis was present. I wonder whether the threshold for calling vasculitis in the retina should be lower than in other tissues. Your input in the comments section would be greatly appreciated.Low power viewMedium power showing diffuse edemaArterioles with focus of intramural inflammatory infiltrate on right side of right vessel (Source: neuropathology blog)
Source: neuropathology blog - March 16, 2017 Category: Radiology Tags: ophthalmic pathology Source Type: blogs
Emory Neuropathologist Dan Brat delivers Nathan Kaufman Timely Topics Lectures at 2017 USCAP annual meeting
On Monday, March 6,Dan Brat, MD, PhD delivered a presentation entitled " Platforms, Diagnosis and Disease: An Evolution Rooted in Pathology " to attendees of the 2017 annual meeting of theUnited States and Canadian Academy of Pathology (USCAP) in San Antonio, Texas. Dr. Brat is director of the neuropathology division of the Emory University pathology Department. (Source: neuropathology blog)
Source: neuropathology blog - March 8, 2017 Category: Radiology Tags: meetings neuropathologists Source Type: blogs
Johns Hopkins Atlas of Surgical Neuropathology now available on iTunes
Dr. EberhartDr. RodriquezSurgical neuropathology is the focus of volume 3 in the Johns Hopkins Atlases of Pathology.This app was released on March 3, 2017 for iPad download for only $4.99 . Authors Charles Eberhart and Fausto Rodriquez introduce us to the next generation in surgical neuropathology reference with a variety of educational features, updates to the 2016 WHO grading system system for CNS tumors, algorithms for the evaluation of diffuse gliomas, and practice quizzes. Congratulations to Drs. Eberhart and Rodriguez on the creation of a magnificent product! (Source: neuropathology blog)
Source: neuropathology blog - March 7, 2017 Category: Radiology Tags: websites Source Type: blogs
Why is the confluence of the cerebral venous sinuses called the " torcula " ?
Torcula is derived from a Latin word meaning to “twist” and was also used to refer to a wine press. Within the cranium the venous sinuses come together at the back of the skull in a structure called the confluence of the sinuses. This cavity has four large veins radiating from it, supposedly resembling the spigots that pour dark purple juice out of the four sides of the ancient wine press used to squeeze grapes with a handled screw on the top. The same stem is found in common words such as torture and tortuous.Source: https://www.dmu.edu/dose/2009/11/anatomy-word-of-the-month-torcular-herophili/ (Source: neuropathology blog)
Source: neuropathology blog - March 3, 2017 Category: Radiology Tags: history Source Type: blogs
Hunched Over a Microscope, Santiago Ramon y Cajal Sketched the Secrets of How the Brain Works
Last month, the Weisman Art Museum in Minneapolis opened a traveling exhibit that is the first dedicated solely to Ram ón y Cajal’s work. According to a New York Times article, it will make stops in Minneapolis; Vancouver, British Columbia; New York City; Cambridge, Mass.; and Chapel Hill, N.C., through April 2019.Ramon y Cajal in his laboratory, circa 1885 Thanks to Drs.Mark Cohen andJohn Evans for alerting me to this exhibit. (Source: neuropathology blog)
Source: neuropathology blog - February 20, 2017 Category: Radiology Tags: history Source Type: blogs
Best Post of November 2016: Calcifying Pseudoneoplasm of the Neuroaxis (CAPNON)
The next in our " Best of the Month " series is from November 11, 2016:Approximately 59 cases of CAPNON have been reported in the literature, A non-neoplastic entity that can be found in either an intra-axial or extra-axial location, the pathogenesis of CAPNON is unclear but a reactive process has been favored. The outcome is generally considered to be excellent, with gross total resection typically curative. This case is somewhat unique in that it harbors adipose tissue.Foci of calcification and fat are present in this midline exampleNodules of basophilic calcificationThe calcifications have a chondromyxoid appearanceSurg...
Source: neuropathology blog - February 16, 2017 Category: Radiology Tags: Best of the Month series reactive processes Source Type: blogs
Ophthalmologist and Eye Pathologist David Wilson Visits University of Colorado Pathology Department
Dr. David Wilson (left) with residents and attendings at University of Colorado Pathology Dept todayThe pathology department was one stop made byDr. David Wilson, ophthalmologist and eye pathologist from Oregon Health and Science University, when he visited the University of Colorado today. (Source: neuropathology blog)
Source: neuropathology blog - February 3, 2017 Category: Radiology Tags: ophthalmic pathology Source Type: blogs
