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Dr. Edward LeeDr. Edward Leeis among several others who have authored an interesting commentary on CTE entitled:Primum non nocere: a call for balance when reporting on CTE. It ' s worth a read! (Source: neuropathology blog)
Source: neuropathology blog - February 15, 2019 Category: Radiology Tags: neuropathologists trauma Source Type: blogs
Neuropathologist Robert Corona named CEO of Upstate Medical University
Robert J. Corona, DO, MBADr. Robert Corona has been named chief executive officer of Upstate University Hospital in Syracuse, NY. Corona had been serving as the hospital ’s interim CEO before his permanent appointment last month.Corona did his neuropathology fellowship at the Armed Forces Institute of Pathology in Washington, DC (1990) and SUNY Health Sciences Center at Syracuse (1991).At Upstate, Corona has served as chair of the pathology department, and medical director of neuropathology. He previously worked as a vice president at Welch Allyn in Skaneateles, NY.Corona was on my 2016 list of neuropathologists who...
Source: neuropathology blog - February 6, 2019 Category: Radiology Tags: neuropathologists Source Type: blogs
Stanford neuropathologist Hannes Vogel featured on cover of the Palo Alto Weekly
Ablog fan spotted this while walking his dog down a street in Palo Alto today:The story aboutDr. Vogel can be seenhere. (Source: neuropathology blog)
Source: neuropathology blog - January 25, 2019 Category: Radiology Tags: neuropathologists Source Type: blogs
Radiologically suspected meningioma turns out to be WHO grade II Pleomorphic Xanthoastrocytoma
Rosethal fiber in oval. Eosinophilic granular body in rectangleRosenthal fibers can be seen in non-neoplastic " compressed " brain tissue. For example, I once saw Rosenthal fibers in the spinal cord adjacent to an epidural abscess. (Source: neuropathology blog)
Source: neuropathology blog - January 18, 2019 Category: Radiology Tags: neoplasms Source Type: blogs
An inquiry from Dr. Mike Lawlor
Dr. Mike Lawlor (Medical College of Wisconsin)Hi Everyone,The time has come for me to pursue re-certification from the American Board of Pathology, and my test period is in March. As I ’ve become a bit super-specialized in a single area, I feel that I’ll likely need to brush up on some topics in order to continue to be considered a neuropathologist. I haven ’t kept up very well with the range and type of educational resources available to neuropathologists for test preparation, and I could use some advice. Does anyone have advice on educational materials appropriate for ABP re-certification in neuro...
Source: neuropathology blog - January 17, 2019 Category: Radiology Tags: books Source Type: blogs
AANP 94th Annual Meeting Highlights on YouTube
Check out thisthree and a half minute video on last year ' s annual meeting of the American Association of Neuropathologists! (Source: neuropathology blog)
Source: neuropathology blog - January 11, 2019 Category: Radiology Tags: meetings Source Type: blogs
Escourolle and Poirier's Manual of Basic Neuropathology, sixth edition, is now available
The newest (2019) edition of this classic is now available! (Source: neuropathology blog)
Source: neuropathology blog - January 10, 2019 Category: Radiology Tags: books Source Type: blogs
The new WHO Ocular Tumour “Blue Book” is now available!
Prepared by 64 contributors from 22 countriesMore than 400 tables and color photos The new edition of the WHO Classification of Tumours of the Eye isnow on sale, just in time for Christmas! The latest edition is edited by Drs. Hans E. Grossniklaus, Charles Eberhart, and Tero Kivela. There are sections on all recognized neoplasms of the eye, lacrimal apparatus, and conjuctiva. Included are substantial changes to the classification of conjunctival neoplasia and melanoma, based on the latest molecular studies. Information on clinical features in addition to prognostic and predictive factors for each tumour typ...
Source: neuropathology blog - December 20, 2018 Category: Radiology Tags: ophthalmic pathology Source Type: blogs
Creating a Google Earth of the Brain
A recentNew York Times article describes a $50 million project by more than a dozen research centers aiming to create a sort ofGoogle Earth of the brain. In a series of 11 papers, published in Science and related journals, a consortium of researchers has produced the most richly detailed model of the brain ’s genetic landscape to date, one that incorporates not only genes but also gene regulators, cellular data and developmental information across the human life span.The PsychENCODE Consortium, initiated in 2015 and financed by the National Institute of Mental Health, involves more than a dozen research centers...
Source: neuropathology blog - December 19, 2018 Category: Radiology Tags: research Source Type: blogs
Best Post of November 2018: The exquisite cellular uniformity of the central neurocytoma
The next in our " Best of the Month " series is from November 20, 2018:Intraoperative ThinPrep smear demonstrates the striking cellular uniformityPermanent section of the same tumor (Source: neuropathology blog)
Source: neuropathology blog - December 14, 2018 Category: Radiology Tags: Best of the Month series neoplasms Source Type: blogs
A Pattern-Based Approach to the Interpretation of Skeletal Muscle Biopsies
Chunyu (Hunter) Cai, MD, PhDChunyu (Hunter) Cai,Douglas Anthony, andPeter Pytel have authored a wonderfully useful review article in Modern Pathology entitledA Pattern-Based Approach to the Interpretation of Skeletal Muscle Biopsies.Dr. Cai wrote the following to me: "In this review, we take a pathology-friendly approach and categorize muscle biopsies into 6 morphologic groups, and discuss common differential diagnoses for each group. I think this review fills a void that there is not a good quick guide for NP fellows, residents and even neuropathologists who don ’t sign out muscle cases on a routine base. " Thanks,...
Source: neuropathology blog - December 10, 2018 Category: Radiology Tags: muscle Source Type: blogs
Giant cell GBM masquerading as an anaplastic PXA
At first glance, this tumor with pleomorphic cells and prominent perivascular lymphocytic cuffing strikes one as a pleomorphic xanthoastrocytoma (PXA).The relative circumscription, as demonstrated by the stark difference in tumor burden in adjacent gyri depicted above also suggests the possibility of PXA.The presence of mitotic figures (center of picture above) and a small amount of necrosis and microvascular proliferation (not pictured) suggests the possibility of anaplastic PXA.However, perivascular lymphocytes and relative circumscription can be seen in giant cell glioblastoma (GC-GBM). Pointing away from anaplast...
Source: neuropathology blog - December 4, 2018 Category: Radiology Tags: neoplasms Source Type: blogs
A middle-aged patient with panhypopituitarism
The clinicoradiological suspicion in this case of a middle-aged patient with panhypopituitarism was hypophysitis.T1 sagittal post-contrastTransphenoidal hypohysectomy yielded the following specimen:Two populations of cells predominate: small monomorphic cells and larger pleomorphic cellsImmunohistochemistry identified the larger pleomorphic cells as representing a large B-cell lymphoma, while the small cells were intermixed non-neoplastic T-cells.This ACTH immunostain demonstrates the progressive obliteration of the pituitary gland by the invading lymphomaDiffuse large B-cell lymphoma presenting as a pituitary mass is rare...
Source: neuropathology blog - November 28, 2018 Category: Radiology Tags: pituitary Source Type: blogs
Unexpected Neuropathology Fellowship opening at Mount Sinai starting July 2019
John F. Crary, MD, PhDDr. John Crary just informed me that his institution, Mount Sinai, has an unexpected opening for a neuropathology fellowship starting in July 2019. Interested candidates can contact him at john.crary@mountsinai.org. (Source: neuropathology blog)
Source: neuropathology blog - November 23, 2018 Category: Radiology Source Type: blogs
Iridociliary melanoma invading sclera
The sclera (upper right part of picture) is being invaded by the heavily pigmented melanoma (Source: neuropathology blog)
Source: neuropathology blog - November 21, 2018 Category: Radiology Tags: eye ophthalmic pathology Source Type: blogs
