Effectiveness and Tolerability of Bisoprolol/Perindopril Single-Pill Combination in Patients with Arterial Hypertension and a History of Myocardial Infarction: The PRIDE Observational Study
CONCLUSION: Treatment of symptomatic patients with CAD, hypertension, and a history of MI with a bisoprolol/perindopril SPC was associated with significant decreases in SBP/DBP and a high proportion of patients achieving BP treatment goals. This was accompanied by improvements in angina symptoms and reductions in HR in a broad patient population representative of those seen in everyday clinical practice.TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT04656847.PMID:37029871 | DOI:10.1007/s12325-023-02462-9 (Source: Adv Data)
Source: Adv Data - April 8, 2023 Category: Epidemiology Authors: Zhanna Kobalava Boris Kvasnikov Yuriy Burtsev PRIDE study investigators Source Type: research
Effectiveness and Tolerability of Bisoprolol/Perindopril Single-Pill Combination in Patients with Arterial Hypertension and a History of Myocardial Infarction: The PRIDE Observational Study
ConclusionTreatment of symptomatic patients with CAD, hypertension, and a history of MI with a bisoprolol/perindopril SPC was associated with significant decreases in SBP/DBP and a high proportion of patients achieving BP treatment goals. This was accompanied by improvements in angina symptoms and reductions in HR in a broad patient population representative of those seen in everyday clinical practice.Trial RegistrationClinicalTrials.gov Identifier NCT04656847. (Source: Advances in Therapy)
Source: Advances in Therapy - April 8, 2023 Category: Drugs & Pharmacology Source Type: research
Managing postoperative atrial fibrillation after open-heart surgery using transdermal β1 blockers
Postoperative atrial fibrillation (POAF) after open-heart surgery is a non-negligible complication. We aimed to describe the efficacy of a transdermal patch of bisoprolol for managing POAF and flutter in thora... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 6, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Kenji Yamamoto, Senri Miwa, Tomoyuki Yamada, Shuji Setozaki, Mamoru Hamuro, Shunji Kurokawa and Sakae Enomoto Tags: Research Source Type: research
α/β- and β-Blocker Exposure in Pregnancy and the Risk of Neonatal Hypoglycemia and Small for Gestational Age
CONCLUSIONS: Carvedilol administration during pregnancy was associated with neonatal hypoglycemia; however, it did not occur in a time- or dose-dependent manner. Routine monitoring of blood glucose levels in newborns exposed to α/β- and β-blockers is essential.PMID:36823100 | DOI:10.1253/circj.CJ-22-0647 (Source: Circulation Journal)
Source: Circulation Journal - February 23, 2023 Category: Cardiology Authors: Kana Kubota Kei Inai Eriko Shimada Tokuko Shinohara Source Type: research
α/β- and β-Blocker Exposure in Pregnancy and the Risk of Neonatal Hypoglycemia and Small for Gestational Age
CONCLUSIONS: Carvedilol administration during pregnancy was associated with neonatal hypoglycemia; however, it did not occur in a time- or dose-dependent manner. Routine monitoring of blood glucose levels in newborns exposed to α/β- and β-blockers is essential.PMID:36823100 | DOI:10.1253/circj.CJ-22-0647 (Source: Circulation Journal)
Source: Circulation Journal - February 23, 2023 Category: Cardiology Authors: Kana Kubota Kei Inai Eriko Shimada Tokuko Shinohara Source Type: research
α/β- and β-Blocker Exposure in Pregnancy and the Risk of Neonatal Hypoglycemia and Small for Gestational Age
CONCLUSIONS: Carvedilol administration during pregnancy was associated with neonatal hypoglycemia; however, it did not occur in a time- or dose-dependent manner. Routine monitoring of blood glucose levels in newborns exposed to α/β- and β-blockers is essential.PMID:36823100 | DOI:10.1253/circj.CJ-22-0647 (Source: Circulation Journal)
Source: Circulation Journal - February 23, 2023 Category: Cardiology Authors: Kana Kubota Kei Inai Eriko Shimada Tokuko Shinohara Source Type: research
Prophylactic Agents for Preventing Cardiotoxicity Induced Following Anticancer Agents: A Systematic Review and Meta-Analysis of Clinical Trials
CONCLUSION: This meta-analysis showed that prophylactic treatment with cardio-protective drugs, including dexrazoxane, beta blocker, and ACEI drugs in patients undergoing chemotherapy with anthracycline, have a protective effect on LVEF and prevent EF drop.PMID:36803186 | DOI:10.2174/1574887118666230118102252 (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - February 21, 2023 Category: Cancer & Oncology Authors: Ehsan Keshavarzian Tella Sadighpour Seyed Mohammadreza Mortazavizadeh Mohammadhossein Soltani Amir Farzin Motevalipoor Shahriyar Shahbazi Khamas Mohammad Moazen Mohamad Kogani Seyed Mohammad Amin Hashemipour Hamid Hosseinpour Rohollah Valizadeh Source Type: research
Prophylactic Agents for Preventing Cardiotoxicity Induced Following Anticancer Agents: A Systematic Review and Meta-Analysis of Clinical Trials
CONCLUSION: This meta-analysis showed that prophylactic treatment with cardio-protective drugs, including dexrazoxane, beta blocker, and ACEI drugs in patients undergoing chemotherapy with anthracycline, have a protective effect on LVEF and prevent EF drop.PMID:36803186 | DOI:10.2174/1574887118666230118102252 (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - February 21, 2023 Category: Cancer & Oncology Authors: Ehsan Keshavarzian Tella Sadighpour Seyed Mohammadreza Mortazavizadeh Mohammadhossein Soltani Amir Farzin Motevalipoor Shahriyar Shahbazi Khamas Mohammad Moazen Mohamad Kogani Seyed Mohammad Amin Hashemipour Hamid Hosseinpour Rohollah Valizadeh Source Type: research
Ambulatory Care Management in Low Blood Pressure Patient with HFrEF
Int J Angiol DOI: 10.1055/s-0043-1761271Heart failure (HF) affects an estimated 38 million people globally, with most published research estimating a prevalence of 1 to 2% of the adult population. Low blood pressure (BP) is reported in 10 to 15% of patients with HF in clinical trials, although this proportion is much more frequent in routine clinical practice. Low BP in outpatients has a better outcome compared to inpatients. Low BP is often a restricting factor in the use and uptitration of guideline-directed medical therapy (GDMT).A 57-year-old male presented himself to the HF clinic with complaints of bloating, shortnes...
Source: International Journal of Angiology - February 8, 2023 Category: Cardiology Authors: Panjaitan, Fajar H. Hasanah, Dian Yaniarti Yonas, Emir Soerarso, Rarsari Tags: Case Report Source Type: research
Beta-Blockers for Primary Prevention of Anthracycline-Induced Cardiac Toxicity: An Updated Meta-Analysis of Randomized Clinical Trials
CONCLUSION: Treatment with beta-blockers prevents dilatation of the left ventricle, development of diastolic dysfunction, and reduction of LVEF. However, these hemodynamic effects do not translate into a significant reduction in CTRCD incidence and prevention of hospitalization for heart failure or cardiac death.PMID:36687509 | PMC:PMC9818032 | DOI:10.1155/2022/8367444 (Source: Cancer Control)
Source: Cancer Control - January 23, 2023 Category: Cancer & Oncology Authors: Armin Attar Arman Karimi Behnagh Mehrasa Hosseini Foad Amanollahi Paria Shafiekhani Ali Kabir Source Type: research
The pathophysiology of Sumatriptan induced non-arteritic anterior ischemic optic neuropathy
Conclusions: In a patient with multiple pathology, we must consider the systemic therapy when performing any clinical examination. Abbreviations: AAION = arteritic anterior ischemic optic neuropathy, AION = anterior ischemic optic neuropathy, BCVA = best corrected visual acuity, BP = blood pressure, CS = corticosteroid, IOP = intraocular pressure, LE = left eye, MRI = magnetic resonance imaging, NAAION = non-arteritic anterior ischemic optic neuropathy, OCT = optical coherence tomography, ON = optic nerve, OU = both eyes, RE = right eye.PMID:36589336 | PMC:PMC9773116 | DOI:10.22336/rjo.2022.62 (Source: Atherosclerosis)
Source: Atherosclerosis - January 2, 2023 Category: Cardiology Authors: Dana D ăscălescu C ătălina Corbu Livia Șram Valeria Coviltir Mihaela Constantin Miruna Burcel Maria Marinescu Andrei Comber Vasile Potop Source Type: research
A Case of Speech-induced Atrial Tachycardia with Presyncope
Intern Med. 2022 Dec 28. doi: 10.2169/internalmedicine.1028-22. Online ahead of print.ABSTRACTSpeech-induced atrial tachycardia (AT) with presyncope is extremely rare. A 52-year-old woman employed at a supermarket reported recurrent presyncope while speaking out loud at her job. Holter electrocardiography revealed AT while swallowing without presyncope. The patient's blood pressure decreased during AT, and she experienced presyncope while saying "IRASSHAIMASE" loudly during a tilt table test. Accordingly, bisoprolol 1.25 mg was prescribed, and the patient did not experience episodes of presyncope with recurrence of AT for ...
Source: Internal Medicine - December 27, 2022 Category: Internal Medicine Authors: Shunichi Doi Toshiyuki Furukawa Haruka Kameshima Osamu Tanaka Tomoo Harada Yoshihiro J Akashi Source Type: research
