Beta-Blockers For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion
In conclusion, beta-blockers serve as an indispensable tool in the realm of modern medical treatment, particularly in managing a broad range of cardiovascular conditions.
Their unique mechanism of action, which includes decreasing heart rate and blood pressure, confers a significant cardio-protective effect.
This, combined with their versatility and the extensive clinical experience with their use, has cemented beta-blockers as a first-line treatment for various conditions, from hypertension and heart failure to anxiety and migraines.
Although beta-blockers present unique benefits, it’s crucial...
Source: The EMT Spot - July 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
32 yo with right sided chest pain. Zero ST Elevation, but that does not matter.
DiscussionIn hindsight I feel there are very few alternative causes for an ECG like this other than an acute LAD occlusion. I believe this is one of those ' subtle STEMI ' cases where neither the ECG nor the symptoms are very obvious or severe and the usual evolution is not seen.I think of these cases as ' insidious infarcts ' and I have seen this in all infarct territories and I do not think they are particularly rare. Essentially the patient is fairly comfortable and the ECG is not obvious but the patient ended up with Q waves, huge troponins and we missed the opportunity to reperfuse the artery when it counts. These pat...
Source: Dr. Smith's ECG Blog - February 17, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs
DM / DNB Cardiology Entrance Mock Test 23
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Source: Cardiophile MD - March 25, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs
DM / DNB Cardiology Entrance Mock Test 7
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Source: Cardiophile MD - January 23, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs
DM / DNB Cardiology Entrance Mock Test 6
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Source: Cardiophile MD - January 22, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
DM / DNB Cardiology Entrance Mock Test 5
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Source: Cardiophile MD - January 20, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs
What is the secret of carvidilol’s superiority in CHF over other beta blockers ?
Beta blockers(BBs) have become key drugs in management of CHF .It helps by blocking toxic effects of inappropriately elevated catecholamine , which is actually a compensatory response(A fight and survival reaction ) from the sympathetic system to a failing heart . This process becomes a liability in the long run as the adrenergic receptors either down regulate or even promote apoptosis and cell death .Along with RASS-ACE it affects every cell in the body promoting neuro- humoral catabolic state.
By trial and error methodology we have found blocking the sympathetic system by BBs confer con...
Source: Dr.S.Venkatesan MD - July 31, 2015 Category: Cardiology Authors: dr s venkatesan Tags: Beta Blocker beta blockers in chf carvidilol vs metoprolol and bisoprolol How carvidilol is superior in chf cardiac failure Source Type: blogs
Contraindication for beta blocker – Cardiology MCQ
Contraindications to beta blocker includes all except:
a) Bradycardia
b) Hypotension
c) Severe bronchospastic airway disease
d) Compensated heart failure
Correct answer: d) Compensated heart failure
Earlier heart failure was considered a contraindication for beta blocker therapy. But now beta blockers are part of standard of care in heart failure as they have been shown to reduce mortality and morbidity in heart failure. Still it is not wise to initiate beta blocker therapy in decompensated heart failure on intravenous diuretics or inotropic support. Beta blockers are initiated after initial stabilization, that too in smal...
Source: Cardiophile MD - May 23, 2015 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Beta blockers in heart failure – Cardiology MCQ
Beta blockers shown to be useful in heart failure include all except:
a) Carvedilol
b) Metoprolol
c) Bisoprolol
d) Atenolol
Correct answer: d) Atenolol
Atenolol is a hydrophilic beta blocker while the rest are lipophilic.
Trials showing efficacy in heart failure:
Carvedilol: COMET Trial [1]
Metoprolol: MERIT-HF Trial [2]
Bisoprolol: CIBIS Trial [3]
References
Poole-Wilson PA, Swedberg K, Cleland JG, Di Lenarda A, Hanrath P, Komajda M, Lubsen J, Lutiger B, Metra M, Remme WJ, Torp-Pedersen C, Scherhag A, Skene A; Carvedilol Or Metoprolol European Trial Investigators. Comparison of carvedilol and metoprolol on clinical ou...
Source: Cardiophile MD - May 8, 2015 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Medications After a Heart Attack
From: www.secondscount.orgYour heart attack recovery will include medications. Taking these medications exactly as prescribed is one of the best tools at your disposal for avoiding death in the months following a heart attack. According to an article published in Circulation, the journal of the American Heart Association, heart attack patients who had not filled any of their prescriptions within 120 days of being discharged from the hospital had 80 percent greater odds of death than those who filled all of their prescriptions.Medications you are likely to be prescribed after a heart attack fall int...
Source: Dr Portnay - January 23, 2015 Category: Cardiology Authors: Dr Portnay Source Type: blogs
Cardiology MCQ: Beta blocker in heart failure
Which of the following beta blocker in heart failure had no benefit?
a) Carvedilol
b) Metoprolol extended release
c) Nebivolol
d) Bucindolol
Correct answer: d) Bucindolol
Bucindolol is a beta blocker with partial agonist activity, which did not reduce mortality in heart failure trial [Beta-Blocker Evaluation of Survival Trial (BEST) Investigators. A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. N Engl J Med. 2001;344:1659 –1667].
Earlier on beta blockers were contraindicated in heart failure because of their negative inotropic effects. But later several large scale trials showed th...
Source: Cardiophile MD - November 28, 2014 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Nebivolol and beta 3 mediated cardioprotection
: Beta 3 adrenoceptor stimulation has been shown to have cardioprotection mediated through nitric oxide synthase which produces nitric oxide. Nebivolol has higher beta 1 selectivity than bisoprolol, carvedilol and bucindolol. Nebivolol is a vasodilatory beta blocker useful in treatment of heart failure in addition to routine uses for beta blockers. The vasodilatory property of nebivolol is probably mediated through stimulation of beta 3 receptors which in turn leads to endothelial nitric oxide synthase (eNOS) activation resulting in the release of nitric oxide. This improves endothelial function and produces peripheral vas...
Source: Cardiophile MD - August 27, 2014 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin, FRCP London Tags: General Cardiology Source Type: blogs
Cardiology MCQ Test 3
Cardiology MCQ Online 3
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Source: Cardiophile MD - July 14, 2013 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Cardiology MCQ Online 3
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You are welcome to try this MCQ set and share it among your friends. Answer key with explanation appears after you complete the test and submit it and press on the view questions button. We strongly advise you t...
Source: Cardiophile MD - July 14, 2013 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
