Bedside Cardiac Pocus in Emergency Setting: A Practice Review.
CONCLUSION: Recent studies have shown promise in establishing best practices for evaluation of heart, lung abdomen and deep vessels At the moment bedside US is widely used in an integrated ultrasound vision just like the holistic view have internal medicine, intensive care and emergency medicine and many medical schools in Europe and the USA are inserting ultrasonography into the core curriculum but we still have to find a standard method for the training program for minimum competence acquisition. PMID: 32738872 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - August 1, 2020 Category: Cancer & Oncology Authors: Zanza C, Longhitano Y, Artico M, Cammarota G, Barbanera A, Racca F, Audo A, Ravera E, Migneco A, Piccioni A, Franceschi F Tags: Rev Recent Clin Trials Source Type: research

Radiation Induced Oral Mucositis in Head and Neck Cancer Patients. Is There Any Effective Management? Review of the Literature the Last Five Years.
CONCLUSION: The management of oral mucositis constitutes an active area of research. In the light of our results we aim to illustrate those treatment strategies that are most effective regarding the treatment approach of oral mucositis. PMID: 32735527 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - July 31, 2020 Category: Cancer & Oncology Authors: Gkantaifi A, Vardas E, Alongi F, Tsoukalas N, Saraireh HH, Charalampakis N, Jozsef L, Hajiioannou J, Kyrodimos E, Tsanadis K, Davide M, Christos C, Iliadis G, Tolia M Tags: Rev Recent Clin Trials Source Type: research

Honey against radiation induced oral mucositis in head and neck cancer patients. An Umbrella Review of Systematic Reviews and Meta-Analyses of the literature.
CONCLUSION: Conventional honey might constitute a highly promising natural product against OM attracting much scientific interest thanks to its easy accessibility and low financial cost. Hence, the lack of studies with high evidence requires further advanced research to enhance the existing knowledge about the potential value of honey in radiation induced OM in H-N cancer patients. PMID: 32646360 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - July 9, 2020 Category: Cancer & Oncology Authors: Gkantaifi A, Alongi F, Vardas E, Cuccia F, Hajiioannou J, Kyrodimos E, Christopoulos C, Mauri D, Charalampakis N, Trogkanis N, Tsoukalas N, Iliadis G, Tolia M Tags: Rev Recent Clin Trials Source Type: research

An Approach to diabetic ketoacidosis in an emergency setting.
CONCLUSION: Furthermore it is essential to monitor potential complications of DKA and if necessary, to treat them and any precipitating events. PMID: 32646361 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - July 9, 2020 Category: Cancer & Oncology Authors: Pitocco D, Di Leo M, Tartaglione L, Rizzo EG, Caputo S, Rizzi A, Pontecorvi A Tags: Rev Recent Clin Trials Source Type: research

Metabolic benefits of probiotic combination with absorbent smectite in type 2 diabetes patients: a randomised controlled trial.
CONCLUSION: Probiotic with smectite due to his absorbent activity and stabilization mucus layer properties can impact on synergistic enhancement of single effect which manifested with significant reduction of IR, waist circumference, markers of chronic systemic inflammation and improvement of glycemic profile as compared to placebo. PMID: 32646362 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - July 9, 2020 Category: Cancer & Oncology Authors: Kobyliak N, Abenavoli L, Falalyeyeva T, Kovalchuk O, Kyriienko D, Komisarenko I Tags: Rev Recent Clin Trials Source Type: research

Serum Uric Acid Level as a Predictive Biomarker of Gestational Hypertension Severity; A Prospective Observational Case-Control Study.
CONCLUSION: Hyperuricemia and increased C-reactive protein and interleukin-1β serum levels correlate with the severity of pregnancy-induced hypertension, and these biomarkers may play a role in the pathogenesis of pre-eclampsia. Serum urate measurement is sensitive, reliable markers that correlate well with the severity of hypertension in pregnant females with pre-eclampsia. PMID: 32646363 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - July 9, 2020 Category: Cancer & Oncology Authors: Sakr HI, Khowailed AA, Al-Fakharany RS, Abdel-Fattah DS, Taha AA Tags: Rev Recent Clin Trials Source Type: research

Disequilibrium and risk of falling in the elderly is a priority for health services.
Abstract The prevention of falls among the elderly is one important public health issue in our aging society. Falls may cause a great deterioration in health among older adults because lead to loss of independence, worsening of quality of life and premature mortality. Epidemiological data show an heavy impact of falls and its consequences on morbidity and mortality. Within a year, more than 30% of persons living in their own homes and more than 50% of persons living in care homes experience at least one fall. One of the main determining factors in the risk of falling in the elderly population is represented by the...
Source: Reviews on Recent Clinical Trials - June 29, 2020 Category: Cancer & Oncology Authors: Chiarella G, Pisani D, Viola P Tags: Rev Recent Clin Trials Source Type: research

Light alcohol drinking and the risk of cancer development: a controversial relationship.
Abstract BACKGROUND: In accordance with the scientific literature heavy alcohol consumption (>50g per day) represents a risk factor for several diseases development, including cancer. However, the oncogenic role of light alcohol drinking (
Source: Reviews on Recent Clinical Trials - June 28, 2020 Category: Cancer & Oncology Authors: Caprio GG, Picascia D, Dallio M, Vitiello PP, Giunta EF, De Falco V, Abenavoli L, Procopio AC, Famiglietti V, Martinelli E, Gravina AG, Federico A, Ciardiello F, Loguercio C, Ciardiello D Tags: Rev Recent Clin Trials Source Type: research

Clinical Management of Infectious Diarrhea.
CONCLUSIONS: Even though the majority of intestinal infections are self-limiting in immunocompetent individuals, specific diagnosis and identification of the causative agent remain crucial from a public health and epidemiological perspective. Specific diagnostic investigation can be reserved for patients with severe dehydration, more severe illness, persistent fever, bloody stools or immunosuppression, and for cases of suspected nosocomial infection or outbreak and it includes complete blood count, creatinine and electrolytes, determination of leukocytes and lactoferrin precence in the stools, stool culture, together with ...
Source: Reviews on Recent Clinical Trials - June 28, 2020 Category: Cancer & Oncology Authors: Siciliano V, Nista EC, Rosà T, Brigida M, Franceschi F Tags: Rev Recent Clin Trials Source Type: research

A Review on the Use of Reversal Agents of Direct Oral Anticogulant Drugs in Case of Gastrointestinal Bleeding.
CONCLUSION: Although these agents have been marketed for five years (idarucizumab) and two years (andexanet alfa) respectively, and despite guidelines considering antidotes as first-line agents in treating life-threatening hemorrhage when available, these antidotes seem to gain access very slowly in the clinical practice. Cost, logistical aspects and need for plasma level determination of DOAC for an accurate therapeutic use probably have an impact on this phenomenon.. An expert multidisciplinary bleeding team should be established so as to implement international guidelines based on local resources and organization. ...
Source: Reviews on Recent Clinical Trials - June 24, 2020 Category: Cancer & Oncology Authors: Ojetti V, Saviano A, Brigida M, Saviano L, Migneco A, Franceschi F Tags: Rev Recent Clin Trials Source Type: research

Management of Pleural Effusions in the Emergency Department.
CONCLUSION: The emergency physician must have a systematic approach that allows rapid recognition, clinical cause identification and definitive management of potential urgent pleural effusions. PMID: 32579507 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - June 24, 2020 Category: Cancer & Oncology Authors: Congedo MT, Ferretti GM, Nachira D, Pennisi MA Tags: Rev Recent Clin Trials Source Type: research

Digitizing the Pharma Neurons - A Technological Operation in Progress!
CONCLUSIONS: With unfolding data on impact of science and technology amalgamation, we need a need shared mindset between data scientists and medical professionals to maximize the utility of enormous health and medical data. To tackle this efficiently, there is a need of cross-collaboration and education, and align with ethical and regulatory requirements. A perfect blend of industry, regulatory, and academia will ensure a successful digitization of pharma neurons. PMID: 32564760 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - June 21, 2020 Category: Cancer & Oncology Authors: Bhardwaj P, Yadav RK, Kurian S Tags: Rev Recent Clin Trials Source Type: research

Multiple Autoimmune Syndrome: An Unusual Combination of Autoimmune Disorders.
CONCLUSION: Patients suffering from an autoimmune disease need special attention as multiple immune mediated disorders may be present simultaneously or sequentially during the course of the disease process. MAS patients are at a higher risk for acquiring infections and tumor development due to prolonged use of immunosuppressants. These patients need close surveillance for the development of another autoimmune disease, so as to control the current disease and to prevent future complications. This case report emphasizes the importance of a multidisciplinary team approach including an immunologist who may facilitate better un...
Source: Reviews on Recent Clinical Trials - June 21, 2020 Category: Cancer & Oncology Authors: Sarfaraz S, Anis S Tags: Rev Recent Clin Trials Source Type: research

Structural And Morphological Changes In The Liver Due To Intestinal Endotoxins.
CONCLUSION: 1. The severity and depth of morphological changes in the liver during endotoxin intoxication were correlated with the dynamics of the content of lipid oxidation products (CD and DK, MDA) and proteins. There was a tendency to a more significant increase in the oxidative modification of proteins in serum. This confirms the data on the primary damage of proteins by free radicals. 2. When exposed to intestinal microflora endotoxin, pronounced dyscirculatory changes, fatty and hydropic degeneration of hepatocytes with signs of toxic damage to their nuclei were determined, but at the same time, increased hyperplasti...
Source: Reviews on Recent Clinical Trials - June 17, 2020 Category: Cancer & Oncology Authors: Malev AL, Zakharova AN, Kaliberdenko VB, Fominykh TA, Kulanthaivel S, Balasundaram K Tags: Rev Recent Clin Trials Source Type: research

Indications for non-invasive ventilation in respiratory failure.
Abstract BACKGROUND: Non-invasive ventilation (NIV) is increasingly being used to treat episodes of acute respiratory failure not only in critical care and respiratory wards, but also in emergency departments. The aim of this review is to summarize the current indications for the management of NIV for respiratory failure. METHODS: Current literature about the topic was reviewed and critically reported to describe the rationale and physiologic advantages of NIV in various situations of respiratory failure. RESULTS: Early NIV use is commonly associated with the significant decrease in endotracheal intubati...
Source: Reviews on Recent Clinical Trials - June 3, 2020 Category: Cancer & Oncology Authors: Navarra SM, Congedo MT, Pennisi MA Tags: Rev Recent Clin Trials Source Type: research

Prevention of COVID-19 infection in the medical population: a possible help from anosmia?.
Abstract COVID-19 asymptomatic cases increases the risks of disease dissemination with even greater risk for physicians given the shortage of personal protective equipment. Here we report on the consistent finding of frequent presentation of anosmia or hyposmia in COVID-19 patients, even in the absence of other symptoms and without other olfactory or nasal findings. In the uncertainty of the clinical characteristics of these patients, this symptom can be a tool to reduce the spread of the infection between medical population. PMID: 32493200 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - June 3, 2020 Category: Cancer & Oncology Authors: Chiarella G, Pizzonato R, Malanga D, Pisani D, Abenavoli L, Viola P Tags: Rev Recent Clin Trials Source Type: research

Management Of Gastrointestinal Bleeding In Rendu-Osler Disease.
CONCLUSION: A combination of medical and endoscopic therapy is probably the best option. PMID: 32493201 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - June 3, 2020 Category: Cancer & Oncology Authors: Tortora A, Marmo C, Gasbarrini A, Costamagna G, Riccioni ME Tags: Rev Recent Clin Trials Source Type: research

Liver Cirrhosis Complications Management At The Emergency Department.
CONCLUSIONS: Although LC prevalence is going to fall in the following years, due to HBV and HCV optimized treatments, its complications represent a significant admission percentage at the ER and challenge for physicians' skills. PMID: 32493202 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - June 3, 2020 Category: Cancer & Oncology Authors: Scarpellini E, Luigiano C, Svegliati-Baroni G, Dumitrascu D, Larussa T, Santori V, Luzza F, Abenavoli L Tags: Rev Recent Clin Trials Source Type: research

Disk Battery Ingestion: A Simple User-Guide.
CONCLUSION: The use of the flow-chart proposed may reduce the risk of consequences and severe injuries for the patients, helping the emergency physician in his decisional process. PMID: 32493203 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - June 3, 2020 Category: Cancer & Oncology Authors: Petruzziello C, Soave PM Tags: Rev Recent Clin Trials Source Type: research

Gender-related differences in sedentary behavior of Japanese living overseas in Malaysia.
Abstract BACKGROUND: The purpose of the present study was to clarify the differences in social demographic factors and sedentary behavior by gender in Japanese living overseas in Malaysia. METHODS: First, 130 subjects were surveyed by self-entry questionnaire for statistical factors related to social demographics and sedentary behavior. These factors were age (years), gender (man/woman), body mass index (BMI, kg/m2 ), educational history (≥13 years, %), employment (full-time or part-time, yes, %), alcohol intake (a certain amount, yes, %), smoking behavior (yes, %), and marital status (yes, %). BMI as obta...
Source: Reviews on Recent Clinical Trials - May 24, 2020 Category: Cancer & Oncology Authors: Izawa KP, Oka K Tags: Rev Recent Clin Trials Source Type: research

YouTube as a source of patients and specialists' information on hemorrhoids and hemorrhoid surgery.
CONCLUSION: Around half of the YouTube videos regarding hemorrhoids topic are misleading or inaccurate and present a risk of harmful consequences. Credible videos with accurate information need to be uploaded by medical professionals and medical institutions and some sort of filtering using categories by the staff of YouTube appear to be necessary. Care must be taken to produce clear highquality operative clips with generous scientific commentary. PMID: 32448106 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - May 24, 2020 Category: Cancer & Oncology Authors: Sturiale A, Dowais R, Porzio FC, Brusciano L, Gallo G, Morganti R, Naldini G Tags: Rev Recent Clin Trials Source Type: research

Review on Recent Trials Evaluating the Effect of Intravitreal Injections of Anti-VEGF Agents on the Macular Perfusion of Diabetic Patients with Diabetic Macular Edema.
CONCLUSION: The large clinical trials recently performed depended mainly on FA in the analysis of MP changes following injections and generally found no worsening of MP. More recently, smaller case series have utilized OCTA in this analysis, yielding more conflicting results. Large randomized controlled trials using OCTA are thus needed. PMID: 32427087 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - May 18, 2020 Category: Cancer & Oncology Authors: Elnahry AG, Abdel-Kader AA, Habib AE, Elnahry GA, Raafat KA, Elrakhawy K Tags: Rev Recent Clin Trials Source Type: research

Conservative treatment of haemorrhoids.
Abstract 1. INTRODUCTION Hemorrhoids are vascular cushions underlying the distal rectal mucosa and contributing for approximately 15-20% of the resting anal pressure with a complete closure of the anal canal. They can become pathological (hemorrhoidal disease, HD) being the most common cause of painless rectal bleeding during defecation with or without prolapsing anal tissue1 . In this case the blood is bright red, not mixed with faeces but instead coated on their outer surface, or dropping after bowel movement. HD is generally classified by its location in internal (originated above the dentate line and covered b...
Source: Reviews on Recent Clinical Trials - May 5, 2020 Category: Cancer & Oncology Authors: Stratta E, Gallo G, Trompetto M Tags: Rev Recent Clin Trials Source Type: research

The management of Hemorrhoidal Disease by Dearterialization and Mucopexy.
tto C Abstract Several minimally invasive surgical procedures have been recently developed to treat hemorrhoids without any excision. About 25 years ago, a non-excisional procedure providing doppler-guided ligation of the hemorrhoidal arteries has been proposed - named "hemorrhoidal dearterialization". The original technique has been modified over the years, and indications were expanded. In particular, a plication of the redundant and prolapsing mucosa/submucosa of the rectum (named "mucopexy") has been introduced to treat hemorrhoidal prolapse, without excision of the hemorrhoidal piles. At p...
Source: Reviews on Recent Clinical Trials - May 5, 2020 Category: Cancer & Oncology Authors: De Simone V, Litta F, Parello A, Campennì P, Orefice R, Marra AA, Goglia M, Ratto C Tags: Rev Recent Clin Trials Source Type: research

Physical Activity and Body Mass Index in Relation to Infertility in Women.
CONCLUSION: We observed some trends and slight difference between outcomes of women with low versus high BMI. There are only a few studies on infertile women with low BMI, and further investigation is warranted. PMID: 32370724 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - May 5, 2020 Category: Cancer & Oncology Authors: Kaneda C, Kanejima Y, Kitamura M, Izawa KP Tags: Rev Recent Clin Trials Source Type: research

Safety and efficacy of Proctosoll Allevia in the Management of Haemorrhoidal Disease in Adults: A prospective randomized clinical trial.
DISCUSSION: The treatment of I-II degree symptomatic HD with Proctosoll Allevia® has demonstrated to be promising with a good profile of tolerability, safety and efficacy. PMID: 32316899 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - April 21, 2020 Category: Cancer & Oncology Authors: Sturiale A, Gallo G, Brusciano L, Cacace T, Cafaro D, Porzio FC, Naldini G Tags: Rev Recent Clin Trials Source Type: research

Are Most of the Published Clinical Trial Results in Restorative Dentistry Invalid? - An Empirical Investigation.
Abstract BACKGROUND: To establish the number of invalid clinical trial reports in restorative dentistry, due to lack of effective randomisation and/or inadequate sample size and whether this number changed, during the 1990 - 2019 period. METHODS: Databases were searched up to 14 July 2019 without limitations regarding publication language. Journal hand search and reference check was conducted for trial reports. Selection criteria were: reporting on a prospective, controlled clinical trial; relevance to placing direct tooth restorations in human vital teeth; direct comparison between restorative materials conc...
Source: Reviews on Recent Clinical Trials - April 21, 2020 Category: Cancer & Oncology Authors: Mickenautsch S Tags: Rev Recent Clin Trials Source Type: research

Circadian rhythms of endothelial nitric oxide synthase and toll-like receptors 2 production in females with rheumatoid arthritis depending on NOS3 gene polymorphism.
CONCLUSIONS: RA patients demonstrated oppositely directed circadian changes of serum NOS3 and sTLR2. CC genotype carriers had lower NOS3 and higher sTLR2 production rates than TT and TC genotype carriers. PMID: 32297585 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - April 16, 2020 Category: Cancer & Oncology Authors: Zaichko K, Zaichko N, Maievskyi O, Korotkyi O, Falalyeyeva T, Fagoonee S, Pellicano R, Abenavoli L, Stanislavchuk M Tags: Rev Recent Clin Trials Source Type: research

Epidemiology of Coronavirus Disease Outbreak: The Italian Trends.
PMID: 32264813 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - April 7, 2020 Category: Cancer & Oncology Authors: Abenavoli L, Cinaglia P, Luzza F, Gentile I, Boccuto L Tags: Rev Recent Clin Trials Source Type: research

Postoperative complications in hemorrhoidal disease and special conditions.
CONCLUSIONS: Pain, urinary retention and bleeding remain the most frequent complications after surgery for hemorrhoids; however, special situations must be taken into account in order to choose the best technique to prevent more severe complications. PMID: 32250228 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - April 6, 2020 Category: Cancer & Oncology Authors: Romaguera VP, Sancho-Muriel J, Alvarez-Sarrdo E, Millan M, Garcia-Granero A, Frasson M Tags: Rev Recent Clin Trials Source Type: research

Anatomy, Physiology and Pathophysiology of Haemorrhoids.
CONCLUSION: Several aspects of etiopathogenesis and pathophysiology remain controversial. Further studies are needed to obtain a better understanding of the disease. PMID: 32250229 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - April 6, 2020 Category: Cancer & Oncology Authors: Pata F, Sgrò A, Ferrara F, Vigorita V, Gallo G, Pellino G Tags: Rev Recent Clin Trials Source Type: research

Hemorrhoidal Laser procedure (HeLP) and Hemorrrrhoidal Laser procedure + mucopexy (HeLPexx) and other Emerging Technologies.
CONCLUSIONS: 'HeLP' is indicated in patients with symptomatic hemorrhoids where conservative treatment failed and when mucosal prolapse is scarce or not symptomatic. The addition of mucopexy to laser treatment (HeLPexx) contributes to overall resolution of symptoms when mucosal prolapse is an issue, Emborrhoid is another novel, 'hi-tech' form of selective dearterialization used in selected case of hemorrhoids where main symptom is bleeding. It is generally used in cases where surgery is contraindicated due to severe concomitant diseases. PMID: 32250230 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - April 6, 2020 Category: Cancer & Oncology Authors: Giamundo P Tags: Rev Recent Clin Trials Source Type: research

Management of Hemorrhoidal Disease in Special Conditions: A Word of Caution.
CONCLUSION: International Literature is very scant about the treatment of patients affected by hemorrhoids in particular situations. A word of caution and concern even about the indication for minor outpatient procedures must be expressed in these patients, in order to avoid possible lifethreatening complications. The first line treatment is the conservative medical approach associated with the treatment of the primary disease. PMID: 32250231 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - April 6, 2020 Category: Cancer & Oncology Authors: Salusso P, Testa V, Mochet S, Arezzo A, Allaix ME, Salzano A, Morino M, Mistrangelo M Tags: Rev Recent Clin Trials Source Type: research

Post Hemorrhoidectomy Pain Management: The Latest News.
Abstract Anal post-operative pain is one of the principal issues of surgical treatment of hemorrhoids and remains a distressing problem, for patients and physicians. Recent studies had concluded that appropriate postoperative pain management lead to higher patient satisfaction, earlier mobilization, fewer drug complications, eliminated adverse events, faster recovery, and decreased health care cost. However, despite advances in pain medicine, postoperative pain control remains problematic and remains an important unresolved issue that causes expense and patient dissatisfaction. Therefore this situation calls for m...
Source: Reviews on Recent Clinical Trials - April 6, 2020 Category: Cancer & Oncology Authors: Chierici A, Frontali A Tags: Rev Recent Clin Trials Source Type: research

The Management of Acute Hemorrhoidal Disease.
Abstract The acute strangulation of internal hemorrhoids and the thrombosis of external hemorrhoids are both debilitating and painful conditions which require immediate treatment in order to minimize morbidity and reduce the length of inactivity. In selected cases, urgent surgical treatment, performed within 72 hours of presentation, prevents the negative economic and psychological effects of a prolonged recovery (which is often the case of conservative management), and limits the necessity for surgical intervention at a later date. PMID: 32223737 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - March 30, 2020 Category: Cancer & Oncology Authors: Selvaggi L, Sciaudone G, Canonico S, Selvaggi F, Pellino G Tags: Rev Recent Clin Trials Source Type: research

Excisional Haemorrhoidectomy: Where Are We?
Abstract Haemorrhoidal disease (HD) is defined as the symptomatic enlargement and/or distal displacement of anal cushions and is one of most frequent and ancient anorectal conditions. Bleeding, during or after defecation, is the most common symptom. The color of the blood is tipically bright red covering the outer surface of the stools. The severity of HD is based on the degree of the prolapse. There are several excisional surgery treatments. In this review we describe the most common techniques such as Milligan and Morgan, Parks, Ferguson and Whitehead technique. Despite significant improvements in conservative t...
Source: Reviews on Recent Clinical Trials - March 19, 2020 Category: Cancer & Oncology Authors: Sena G, Gallo G, Vescio G, Diaco E, Papandrea M, Trompetto M, Sammarco G, Carpino A Tags: Rev Recent Clin Trials Source Type: research

Scoring System for Haemorrhoidal Disease.
Abstract Hemorrhoidal Disease (HD) is widely diffused throughout the general population. The system of classification currently used to categorize this pathology is that of Goligher (1975). This system only defines the morphology of the most represented hemorrhoid bearing. Several attempts in literature have been made to replace this system, but as of yet, no single system has been universally accepted. Some studies, however, have succeeded in identifying specific characteristics, besides morphology, that would be able to aptly define HD. An analysis of this literature, with careful consideration of the scores tha...
Source: Reviews on Recent Clinical Trials - March 19, 2020 Category: Cancer & Oncology Authors: Romano FM, Sciaudone G, Canonico S, Selvaggi F, Pellino G Tags: Rev Recent Clin Trials Source Type: research

Classifications and Clinical Assessment of Haemorrhoids:The Proctologist's Corner.
CONCLUSION: Preoperative clinical evaluation is essential for HD patient treatment and outcome. Classification systems are useful for the therapeutic choice and for researches on new medical or surgical treatments. In fact, the international guidelines advise several therapeutic options depending on the severity of the HD. PMID: 32164517 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - March 12, 2020 Category: Cancer & Oncology Authors: Picciariello A, Tsarkov P, Papagni V, Efetov S, Markaryan D, Tulina I, Picciariello DF Tags: Rev Recent Clin Trials Source Type: research

Do We Have Another Option to Treat Bleeding Hemorrhoids? The Emborrhoid Technique: Experience in 16 Patients.
CONCLUSION: Our study, although small in number, demonstrates that embolization of superior rectal arteries with coils to treat severe bleeding due to hemorrhoids is safe and effective and does not lead to immediate complications. PMID: 32167429 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - March 12, 2020 Category: Cancer & Oncology Authors: Moggia E, Talamo G, Gallo G, Gallo G, Barattini M, Salsano G, Zefiro D, Stefanini T, Berti S Tags: Rev Recent Clin Trials Source Type: research

Stapled Surgery for Hemorrhoidal Prolapse: From the Beginning to the Modern Times.
CONCLUSIONS: Stapled procedure for the treatment of symptomatic hemorrhoidal prolapse represents one of the most important innovations in proctology of the last century bringing with it the new revolutionary concept of the rectal intussusception as a determining factor involved in the natural history of the disease. Stapled hemorrhoidopexy marked an era in which the surgeon may to offer to the patients a safe, effective treatment with less pain and fast recovery. PMID: 32156241 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - March 10, 2020 Category: Cancer & Oncology Authors: Sturiale A, Fabiani B, Menconi C, Cafaro D, Porzio FC, Naldini G Tags: Rev Recent Clin Trials Source Type: research

Outpatient Treatment of Hemorrhoidal Disease: The Alternative Way to Treat Hemorrhoidal Disease in a Simple, Safe and Effective Manner.
CONCLUSION: The proctological clinics must evaluate the quality of life offered to patients and discuss with them the appropriate treatment in order to select the most appropriate one for symptoms resolution and disease cure. Less is not always the best but can be an alternative to be offered. PMID: 32133966 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - March 5, 2020 Category: Cancer & Oncology Authors: Tutino R, Salamone G, De Marco P, Cocorullo G, Gulotta G Tags: Rev Recent Clin Trials Source Type: research

COVID-19: Perspectives on the Potential Novel Global Threat.
PMID: 32116200 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - February 27, 2020 Category: Cancer & Oncology Authors: Gentile I, Abenavoli L Tags: Rev Recent Clin Trials Source Type: research

Breastfeeding following Kangaroo Mother Care.
PMID: 32075573 [PubMed - in process] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - February 23, 2020 Category: Cancer & Oncology Authors: Puri BK Tags: Rev Recent Clin Trials Source Type: research

Serum Levels of Granulocyte-Macrophage-Colony-Stimulating Factor and Stem-Cell Factor During Liver Regeneration after Partial Hepatectomy in Humans.
Abstract BACKGROUND: Multiple biological functions have been recognized regarding granulocyte macrophage-colony stimulating factor (GM-CSF) and stem cell factor (SCF). AIM: To evaluate the serum changes of GM-CSF and SCF in patients undergoing surgical resection for liver tumor, in the regenerative phase after surgery in order to identify the possible relationship with patient, tumor or surgical variables. METHODS: Thirty-two consecutive patients (50% male, median age 66) undergoing hepatic resection of liver neoplasm, were evaluated. The liver tumor was a hepatocellular carcinoma (HCC) in 44% of cases. ...
Source: Reviews on Recent Clinical Trials - January 22, 2020 Category: Cancer & Oncology Authors: Fiume D, Lenci I, Milana M, Manzia TM, Massoud R, Tariciotti L, Russo C, Toti L, Baiocchi L Tags: Rev Recent Clin Trials Source Type: research

The Use of Thiopurine Derivatives in the Treatment of Inflammatory Bowel Disease.
PMID: 31735159 [PubMed - in process] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - November 19, 2019 Category: Cancer & Oncology Authors: Puri BK Tags: Rev Recent Clin Trials Source Type: research

Potential Involvement of Impaired Venous Outflow from the Brain in Neurodegeneration: Lessons Learned from the Research on Chronic Cerebrospinal Venous Insufficiency.
Abstract About 10 years ago, the so-called chronic cerebrospinal venous insufficiency syndrome was discovered. This clinical entity, which is associated with extracranial venous abnormalities that impair venous outflow from the brain, was initially found exclusively in multiple sclerosis patients. Currently, we know that such venous lesions can also be revealed in other neurological pathologies, including Alzheimer's and Parkinson's diseases. Although direct causative role of chronic cerebrospinal venous insufficiency in these neurological diseases still remains elusive, in this paper, we suggest that perhaps an a...
Source: Reviews on Recent Clinical Trials - November 19, 2019 Category: Cancer & Oncology Authors: Simka M, Skuła M Tags: Rev Recent Clin Trials Source Type: research

Comparing Intradermal Sterile Water with Intravenous Morphine in Reducing Pain in Patients with Renal Colic: A Double-Blind Randomized Clinical Trial.
Abstract OBJECTIVE: The present study was conducted to investigate the effect of intradermal administration of sterile water compared to intravenous morphine on patients with renal colic. METHODS: This double-blind randomized clinical trial study was conducted in 2017 to compare the therapeutic effects of intradermal sterile water with those of intravenous morphine on patients with renal colic presenting to the emergency departments (ED) of Imam Khomeini and Golestan Hospitals in Ahvaz, Iran. The first group received 0.5 ml of intradermal sterile water, and the second group 0.1 mg/kg of intravenous morphine p...
Source: Reviews on Recent Clinical Trials - November 18, 2019 Category: Cancer & Oncology Authors: Mozaffari J, Verki MM, Tirandaz F, Mahjouri R Tags: Rev Recent Clin Trials Source Type: research

The Role of Hyperhomocysteinemia on the Development of Changes in the Lungs.
CONCLUSION: Mature animals of the experimental group are characterized by activation of inflammatory processes, oxidative stress, due to increased production of macrophages and, as a consequence, the launch of the humorous link of immunity, while in old rats were determined by fibrosis, disorders of the trophic and gas metabolism, as well as damage to the endothelium part of lungs. PMID: 31729946 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - November 14, 2019 Category: Cancer & Oncology Authors: Maievskyi O, Samborska I, Kovalchuk O, Fagoonee S, Falalyeyeva T Tags: Rev Recent Clin Trials Source Type: research

Benign Intracranial Lesions - Radiotherapy: An Overview of Treatment Options, Indications and Therapeutic Results.
CONCLUSION: RT comprises an effective treatment modality of benign brain and intracranial lesions. By minimizing its ares with optimal use, RT projects as a potent tool against such diseases. PMID: 31713498 [PubMed - as supplied by publisher] (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - November 10, 2019 Category: Cancer & Oncology Authors: Tzikoulis V, Gkantaifi A, Alongi F, Tsoukalas N, Saraireh HH, Charalampakis N, Tzikoulis G, Andreou E, Tsapakidis K, Kardamakis D, Tsanadis K, Kyrgias G, Tolia M Tags: Rev Recent Clin Trials Source Type: research

Efficacy and Safety of Non-Steroidal Anti-Androgens in Patients with Metastatic Prostate Cancer: Meta-Analysis of Randomized Controlled Trials.
Abstract BACKGROUND: Prostate cancer (PCa), the sixth primary cause of cancer death. Still, conflicts are present about the efficacy and safety of Non-steroidal anti-androgens (NSAA). Aim of this study was to assess the efficacy and safety of NSAAs versus any comparator for the treatment of advanced or metastatic PCa. METHODOLOGY: MEDLINE and the Cochrane Library were searched. References of included studies and clinicaltrials.gov were also searched for relevant studies. Only English language studies after 1990 were considered for review. Randomized controlled trials (RCTs) examining the efficacy and safety o...
Source: Reviews on Recent Clinical Trials - November 5, 2019 Category: Cancer & Oncology Authors: Rashid M, Ramesh M, Shamshavali K, Dang A, Patel H, Undela K Tags: Rev Recent Clin Trials Source Type: research