Potential Indications of Dupilumab in Th-2 Inflammatory Disease
Rev Recent Clin Trials. 2023 Dec 20. doi: 10.2174/0115748871263396231121060901. Online ahead of print.ABSTRACTDupilumab is a fully humanized IgG4 monoclonal antibody, inhibiting IL-4 and IL-13 signaling, which are the main cytokines involved in type 2 inflammatory diseases. Its introduction was a breakthrough in the treatment of moderate-to-severe atopic dermatitis, but it is also used in other inflammatory diseases, including asthma, eosinophilic esophagitis and chronic rhinosinusitis with nasal polyposis. Recent advances in the understanding of inflammatory pathways have revealed that Th2-type inflammation is involved in...
Source: Reviews on Recent Clinical Trials - December 23, 2023 Category: Cancer & Oncology Authors: Proietti Ilaria Skroza Nevena Tolino Ersilia Bernardini Nicoletta Federica Trovato Marco Di Fraia Dybala Agniezska Potenza Concetta Source Type: research
Potential Indications of Dupilumab in Th-2 Inflammatory Disease
Rev Recent Clin Trials. 2023 Dec 20. doi: 10.2174/0115748871263396231121060901. Online ahead of print.ABSTRACTDupilumab is a fully humanized IgG4 monoclonal antibody, inhibiting IL-4 and IL-13 signaling, which are the main cytokines involved in type 2 inflammatory diseases. Its introduction was a breakthrough in the treatment of moderate-to-severe atopic dermatitis, but it is also used in other inflammatory diseases, including asthma, eosinophilic esophagitis and chronic rhinosinusitis with nasal polyposis. Recent advances in the understanding of inflammatory pathways have revealed that Th2-type inflammation is involved in...
Source: Reviews on Recent Clinical Trials - December 23, 2023 Category: Cancer & Oncology Authors: Proietti Ilaria Skroza Nevena Tolino Ersilia Bernardini Nicoletta Federica Trovato Marco Di Fraia Dybala Agniezska Potenza Concetta Source Type: research
Potential Indications of Dupilumab in Th-2 Inflammatory Disease
Rev Recent Clin Trials. 2023 Dec 20. doi: 10.2174/0115748871263396231121060901. Online ahead of print.ABSTRACTDupilumab is a fully humanized IgG4 monoclonal antibody, inhibiting IL-4 and IL-13 signaling, which are the main cytokines involved in type 2 inflammatory diseases. Its introduction was a breakthrough in the treatment of moderate-to-severe atopic dermatitis, but it is also used in other inflammatory diseases, including asthma, eosinophilic esophagitis and chronic rhinosinusitis with nasal polyposis. Recent advances in the understanding of inflammatory pathways have revealed that Th2-type inflammation is involved in...
Source: Reviews on Recent Clinical Trials - December 23, 2023 Category: Cancer & Oncology Authors: Proietti Ilaria Skroza Nevena Tolino Ersilia Bernardini Nicoletta Federica Trovato Marco Di Fraia Dybala Agniezska Potenza Concetta Source Type: research
Confidence Interval: Advantages, Disadvantages and the Dilemma of Interpretation
Rev Recent Clin Trials. 2023 Dec 1. doi: 10.2174/0115748871266250231120043345. Online ahead of print.ABSTRACTConfidence interval (CI) is one of the important reporting tools for research data as it not only provides valuable information about the effect size along with its width but also possible clinical significance. Unfortunately, this approach is not being utilized to its fullest extent. Determining point estimate always includes an element of uncertainty due to associated sampling error. A confidence interval may be an appropriate tool to measure this uncertainty. Further, the P value does not convey information about...
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Pramod K Sharma Mamta Yadav Source Type: research
Comparison of the Effects of Govarcin Herbal Capsule and Metoclopramide for Alleviating Gastrointestinal Symptoms in Patients with Functional Dyspepsia: A Randomized Double-blind Clinical Trial
CONCLUSION: Govarcin herbal capsule can be used to remedy symptoms in patients with FD. It seems that Guarcin is as effective as metoclopramide in fighting symptoms of FD as no significant difference in efficacy has been demonstrated between them.PMID:38099534 | DOI:10.2174/0115748871266848231120112355 (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Majid Asghari Sajjad Ahmadpour Mikaeil Molazadeh Mohammad Mehdi Jafari Ahmad Hormati Mohammad Reza Pashaei Yousef Mohammadpour Mohamad Amin Habibi Abolfazl Mohammadbeigi Seyed Mahmoud Eshagh Hoseini Source Type: research
Confidence Interval: Advantages, Disadvantages and the Dilemma of Interpretation
Rev Recent Clin Trials. 2023 Dec 1. doi: 10.2174/0115748871266250231120043345. Online ahead of print.ABSTRACTConfidence interval (CI) is one of the important reporting tools for research data as it not only provides valuable information about the effect size along with its width but also possible clinical significance. Unfortunately, this approach is not being utilized to its fullest extent. Determining point estimate always includes an element of uncertainty due to associated sampling error. A confidence interval may be an appropriate tool to measure this uncertainty. Further, the P value does not convey information about...
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Pramod K Sharma Mamta Yadav Source Type: research
Comparison of the Effects of Govarcin Herbal Capsule and Metoclopramide for Alleviating Gastrointestinal Symptoms in Patients with Functional Dyspepsia: A Randomized Double-blind Clinical Trial
CONCLUSION: Govarcin herbal capsule can be used to remedy symptoms in patients with FD. It seems that Guarcin is as effective as metoclopramide in fighting symptoms of FD as no significant difference in efficacy has been demonstrated between them.PMID:38099534 | DOI:10.2174/0115748871266848231120112355 (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Majid Asghari Sajjad Ahmadpour Mikaeil Molazadeh Mohammad Mehdi Jafari Ahmad Hormati Mohammad Reza Pashaei Yousef Mohammadpour Mohamad Amin Habibi Abolfazl Mohammadbeigi Seyed Mahmoud Eshagh Hoseini Source Type: research
Confidence Interval: Advantages, Disadvantages and the Dilemma of Interpretation
Rev Recent Clin Trials. 2023 Dec 1. doi: 10.2174/0115748871266250231120043345. Online ahead of print.ABSTRACTConfidence interval (CI) is one of the important reporting tools for research data as it not only provides valuable information about the effect size along with its width but also possible clinical significance. Unfortunately, this approach is not being utilized to its fullest extent. Determining point estimate always includes an element of uncertainty due to associated sampling error. A confidence interval may be an appropriate tool to measure this uncertainty. Further, the P value does not convey information about...
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Pramod K Sharma Mamta Yadav Source Type: research
Comparison of the Effects of Govarcin Herbal Capsule and Metoclopramide for Alleviating Gastrointestinal Symptoms in Patients with Functional Dyspepsia: A Randomized Double-blind Clinical Trial
CONCLUSION: Govarcin herbal capsule can be used to remedy symptoms in patients with FD. It seems that Guarcin is as effective as metoclopramide in fighting symptoms of FD as no significant difference in efficacy has been demonstrated between them.PMID:38099534 | DOI:10.2174/0115748871266848231120112355 (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Majid Asghari Sajjad Ahmadpour Mikaeil Molazadeh Mohammad Mehdi Jafari Ahmad Hormati Mohammad Reza Pashaei Yousef Mohammadpour Mohamad Amin Habibi Abolfazl Mohammadbeigi Seyed Mahmoud Eshagh Hoseini Source Type: research
Confidence Interval: Advantages, Disadvantages and the Dilemma of Interpretation
Rev Recent Clin Trials. 2023 Dec 1. doi: 10.2174/0115748871266250231120043345. Online ahead of print.ABSTRACTConfidence interval (CI) is one of the important reporting tools for research data as it not only provides valuable information about the effect size along with its width but also possible clinical significance. Unfortunately, this approach is not being utilized to its fullest extent. Determining point estimate always includes an element of uncertainty due to associated sampling error. A confidence interval may be an appropriate tool to measure this uncertainty. Further, the P value does not convey information about...
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Pramod K Sharma Mamta Yadav Source Type: research
Comparison of the Effects of Govarcin Herbal Capsule and Metoclopramide for Alleviating Gastrointestinal Symptoms in Patients with Functional Dyspepsia: A Randomized Double-blind Clinical Trial
CONCLUSION: Govarcin herbal capsule can be used to remedy symptoms in patients with FD. It seems that Guarcin is as effective as metoclopramide in fighting symptoms of FD as no significant difference in efficacy has been demonstrated between them.PMID:38099534 | DOI:10.2174/0115748871266848231120112355 (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Majid Asghari Sajjad Ahmadpour Mikaeil Molazadeh Mohammad Mehdi Jafari Ahmad Hormati Mohammad Reza Pashaei Yousef Mohammadpour Mohamad Amin Habibi Abolfazl Mohammadbeigi Seyed Mahmoud Eshagh Hoseini Source Type: research
Confidence Interval: Advantages, Disadvantages and the Dilemma of Interpretation
Rev Recent Clin Trials. 2023 Dec 1. doi: 10.2174/0115748871266250231120043345. Online ahead of print.ABSTRACTConfidence interval (CI) is one of the important reporting tools for research data as it not only provides valuable information about the effect size along with its width but also possible clinical significance. Unfortunately, this approach is not being utilized to its fullest extent. Determining point estimate always includes an element of uncertainty due to associated sampling error. A confidence interval may be an appropriate tool to measure this uncertainty. Further, the P value does not convey information about...
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Pramod K Sharma Mamta Yadav Source Type: research
Comparison of the Effects of Govarcin Herbal Capsule and Metoclopramide for Alleviating Gastrointestinal Symptoms in Patients with Functional Dyspepsia: A Randomized Double-blind Clinical Trial
CONCLUSION: Govarcin herbal capsule can be used to remedy symptoms in patients with FD. It seems that Guarcin is as effective as metoclopramide in fighting symptoms of FD as no significant difference in efficacy has been demonstrated between them.PMID:38099534 | DOI:10.2174/0115748871266848231120112355 (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Majid Asghari Sajjad Ahmadpour Mikaeil Molazadeh Mohammad Mehdi Jafari Ahmad Hormati Mohammad Reza Pashaei Yousef Mohammadpour Mohamad Amin Habibi Abolfazl Mohammadbeigi Seyed Mahmoud Eshagh Hoseini Source Type: research
Confidence Interval: Advantages, Disadvantages and the Dilemma of Interpretation
Rev Recent Clin Trials. 2023 Dec 1. doi: 10.2174/0115748871266250231120043345. Online ahead of print.ABSTRACTConfidence interval (CI) is one of the important reporting tools for research data as it not only provides valuable information about the effect size along with its width but also possible clinical significance. Unfortunately, this approach is not being utilized to its fullest extent. Determining point estimate always includes an element of uncertainty due to associated sampling error. A confidence interval may be an appropriate tool to measure this uncertainty. Further, the P value does not convey information about...
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Pramod K Sharma Mamta Yadav Source Type: research
Comparison of the Effects of Govarcin Herbal Capsule and Metoclopramide for Alleviating Gastrointestinal Symptoms in Patients with Functional Dyspepsia: A Randomized Double-blind Clinical Trial
CONCLUSION: Govarcin herbal capsule can be used to remedy symptoms in patients with FD. It seems that Guarcin is as effective as metoclopramide in fighting symptoms of FD as no significant difference in efficacy has been demonstrated between them.PMID:38099534 | DOI:10.2174/0115748871266848231120112355 (Source: Reviews on Recent Clinical Trials)
Source: Reviews on Recent Clinical Trials - December 15, 2023 Category: Cancer & Oncology Authors: Majid Asghari Sajjad Ahmadpour Mikaeil Molazadeh Mohammad Mehdi Jafari Ahmad Hormati Mohammad Reza Pashaei Yousef Mohammadpour Mohamad Amin Habibi Abolfazl Mohammadbeigi Seyed Mahmoud Eshagh Hoseini Source Type: research
