Women in engineering, science and technology in sub-Saharan Africa: cultural attitudes, challenges, and gaps affecting clinical engineering and medical devices maintenance practices
ConclusionsThere is an apparent need to further study the possible effects of this sociological model through leveraging local culture and domestic traditions in ways that could ultimately increase the leadership and numbers of women BMETs in SSA. (Source: Health and Technology)
Source: Health and Technology - April 26, 2024 Category: Information Technology Source Type: research

Morphological-metabolic analysis in Streptomyces rimosus microparticle-enhanced cultivations (MPEC)
Bioprocess Biosyst Eng. 2024 Apr 25. doi: 10.1007/s00449-024-03015-2. Online ahead of print.ABSTRACTStreptomyces produce a broad spectrum of biologically active molecules such as oxytetracycline and rimocidin, which are widely used in human and animal treatments. microparticle-enhanced cultivation (MPEC) is one of the tools used for Streptomyces bioprocesses intensification by the control of mycelial morphology. In the present work, morphological changes of Streptomyces rimosus caused by the addition of 10 µm talc microparticles in MPEC were correlated with the biosynthetic activity of the microorganism. Comparing the run...
Source: Bioprocess and Biosystems Engineering - April 25, 2024 Category: Biomedical Engineering Authors: Anna Ścigaczewska Tomasz Boruta Marcin Bizukoj ć Source Type: research

Correction: Ethical Considerations of Neuralink and Brain-Computer Interfaces
Ann Biomed Eng. 2024 Apr 24. doi: 10.1007/s10439-024-03524-x. Online ahead of print.NO ABSTRACTPMID:38656638 | DOI:10.1007/s10439-024-03524-x (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - April 24, 2024 Category: Biomedical Engineering Authors: Ethan Waisberg Joshua Ong Andrew G Lee Source Type: research

Automatic segmentation of tumour and organs at risk in 3D MRI for cervical cancer radiation therapy with anatomical variations
AbstractCervical cancer is a common cancer in women globally, with treatment usually involving radiation therapy (RT). Accurate segmentation for the tumour site and organ-at-risks (OARs) could assist in the reduction of treatment side effects and improve treatment planning efficiency. Cervical cancer Magnetic Resonance Imaging (MRI) segmentation is challenging due to a limited amount of training data available and large inter- and intra- patient shape variation for OARs. The proposed Masked-Net consists of a masked encoder within the 3D U-Net to account for the large shape variation within the dataset, with additional dila...
Source: Australasian Physical and Engineering Sciences in Medicine - April 24, 2024 Category: Biomedical Engineering Source Type: research

Design and optimization of an octuple-electrode array for micro-particle chain rotation via electrorotation integrated with machine vision technology
Analyst, 2024, Accepted Manuscript DOI: 10.1039/D4AN00441H, PaperZhijie Huan, Zexiang Chen, Xiongbiao Zheng, Yiwei Zhang, Jingjie Zhang, Weicheng Ma Microparticles rotation is an important process in biomedical engineering, such as biosensor, cell injection or cell morphology. Single particle rotation has been widely investigated, while rotation of particle chain has... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - April 23, 2024 Category: Chemistry Authors: Zhijie Huan Source Type: research

Vein segmentation and visualization of upper and lower extremities using convolution neural network
CONCLUSIONS: Self-parameterized U-Net for vein segmentation and visualization has the potential to reduce risks associated with traditional venipuncture or CVD treatments by outperforming conventional CNN architectures, providing vascular assistance, and improving patient care and treatment outcomes.PMID:38651783 | DOI:10.1515/bmt-2023-0331 (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - April 23, 2024 Category: Biomedical Engineering Authors: Amit Laddi Shivalika Goyal None Himani Ajay Savlania Source Type: research

Microfluidics as an emerging paradigm for assisted reproductive technology: A sperm separation perspective
We present various sperm separation microfluidic techniques, categorized as natural and non-natural methods. A few of the recent developments in on-chip fertilization are also discussed.PMID:38652182 | DOI:10.1007/s10544-024-00705-2 (Source: Biomedical Microdevices)
Source: Biomedical Microdevices - April 23, 2024 Category: Biomedical Engineering Authors: Mohammadjavad Bouloorchi Tabalvandani Zahra Saeidpour Zahra Habibi Saeed Javadizadeh Seyed Ahmadreza Firoozabadi Majid Badieirostami Source Type: research

Impact of fed-batch process intensification on the productivity and product quality of two CHO cell lines expressing unique novel molecular format proteins
In this study, the impact of a high inoculation density (HID) fed-batch process on the productivity and product quality attributes of two CHO cell lines expressing unique NMFs, a monospecific antibody with an Fc-fusion protein and a bispecific antibody, compared to low inoculation density (LID) platform fed-batch processes was evaluated. It was observed that an intensified platform fed-batch process increased product concentrations by 33 and 109% for the two uniquely structured complex proteins in a shorter culture duration while maintaining similar product quality attributes to traditional fed-batch processes.PMID:3865384...
Source: Bioprocess and Biosystems Engineering - April 23, 2024 Category: Biomedical Engineering Authors: Nicolas Q Wolnick Marissa R Dickson Thaddaeus A Webster Roger P Connolly Nancy Fernandes Vesela Encheva Hunter Crittenden Jessica Hodgkins Brian C Hadley Gabriella Palermo Shannon J Hendrick Roy A Newell Genevieve Gray Christian Siltanen Julia Armstrong B Source Type: research

Electromagnetic Modulation of Cell Behavior: Unraveling the Positive Impacts in a Comprehensive Review
Ann Biomed Eng. 2024 Apr 23. doi: 10.1007/s10439-024-03519-8. Online ahead of print.ABSTRACTThere are numerous effective procedures for cell signaling, in which humans directly transmit detectable signals to cells to govern their essential behaviors. From a biomedical perspective, the cellular response to the combined influence of electrical and magnetic fields holds significant promise in various domains, such as cancer treatment, targeted drug delivery, gene therapy, and wound healing. Among these modern cell signaling methods, electromagnetic fields (EMFs) play a pivotal role; however, there remains a paucity of knowled...
Source: Annals of Biomedical Engineering - April 23, 2024 Category: Biomedical Engineering Authors: Amirhossein Bahmanpour Seyed Majid Ghoreishian Azadeh Sepahvandi Source Type: research

Vein segmentation and visualization of upper and lower extremities using convolution neural network
CONCLUSIONS: Self-parameterized U-Net for vein segmentation and visualization has the potential to reduce risks associated with traditional venipuncture or CVD treatments by outperforming conventional CNN architectures, providing vascular assistance, and improving patient care and treatment outcomes.PMID:38651783 | DOI:10.1515/bmt-2023-0331 (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - April 23, 2024 Category: Biomedical Engineering Authors: Amit Laddi Shivalika Goyal None Himani Ajay Savlania Source Type: research

Microfluidics as an emerging paradigm for assisted reproductive technology: A sperm separation perspective
We present various sperm separation microfluidic techniques, categorized as natural and non-natural methods. A few of the recent developments in on-chip fertilization are also discussed.PMID:38652182 | DOI:10.1007/s10544-024-00705-2 (Source: Biomedical Microdevices)
Source: Biomedical Microdevices - April 23, 2024 Category: Biomedical Engineering Authors: Mohammadjavad Bouloorchi Tabalvandani Zahra Saeidpour Zahra Habibi Saeed Javadizadeh Seyed Ahmadreza Firoozabadi Majid Badieirostami Source Type: research

Impact of fed-batch process intensification on the productivity and product quality of two CHO cell lines expressing unique novel molecular format proteins
In this study, the impact of a high inoculation density (HID) fed-batch process on the productivity and product quality attributes of two CHO cell lines expressing unique NMFs, a monospecific antibody with an Fc-fusion protein and a bispecific antibody, compared to low inoculation density (LID) platform fed-batch processes was evaluated. It was observed that an intensified platform fed-batch process increased product concentrations by 33 and 109% for the two uniquely structured complex proteins in a shorter culture duration while maintaining similar product quality attributes to traditional fed-batch processes.PMID:3865384...
Source: Bioprocess and Biosystems Engineering - April 23, 2024 Category: Biomedical Engineering Authors: Nicolas Q Wolnick Marissa R Dickson Thaddaeus A Webster Roger P Connolly Nancy Fernandes Vesela Encheva Hunter Crittenden Jessica Hodgkins Brian C Hadley Gabriella Palermo Shannon J Hendrick Roy A Newell Genevieve Gray Christian Siltanen Julia Armstrong B Source Type: research

Video-based analysis of the blink reflex in Parkinson ’s disease patients
We developed a video-based tool to quantitatively assess the Glabellar Tap Reflex (GTR) in patients with idiopathic Parkinson ’s disease (iPD) as well as healthy age-matched participants. We also video-graphica... (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - April 23, 2024 Category: Biomedical Engineering Authors: Talisa S. Jansen, G ökhan Güney, Bergita Ganse, Mariana H. G. Monje, Jörg B. Schulz, Manuel Dafotakis, Christoph Hoog Antink and Anne K. Braczynski Tags: Research Source Type: research

A mechanistic simulation of induced DNA damage in a bacterial cell by X- and gamma rays: a parameter study
AbstractMechanistic Monte Carlo simulations calculating DNA damage caused by ionizing radiation are highly dependent on the simulation parameters. In the present study, using the Geant4-DNA toolkit, the impact of different parameters on DNA damage induced in a bacterial cell by X- and gamma-ray irradiation was investigated. Three geometry configurations, including the simple (without DNA details), the random (a random multiplication of identical DNA segments), and the fractal (a regular replication of DNA segments using fractal Hilbert curves), were simulated. Also, three physics constructors implemented in Geant4-DNA, i.e...
Source: Australasian Physical and Engineering Sciences in Medicine - April 23, 2024 Category: Biomedical Engineering Source Type: research

Transfer learning and self-distillation for automated detection of schizophrenia using single-channel EEG and scalogram images
In this study, our main goal is to develop an optimized system that can achieve automatic diagnosis of SZ with minimal input information. To optimize the system, we adopted a strategy of using single-channel EEG signals and integrated knowledge distillation and transfer learning techniques into the model. This approach was designed to improve the performance and efficiency of our proposed method for SZ diagnosis. Additionally, to leverage the pre-trained models effectively, we converted the EEG signals into images using Continuous Wavelet Transform (CWT). This transformation allowed us to harness the capabilities of pre-tr...
Source: Australasian Physical and Engineering Sciences in Medicine - April 23, 2024 Category: Biomedical Engineering Source Type: research