Comparative study of plaque surface temperature and blood heat transfer in a stenosed blood vessel with different symmetrical configurations
This study aims to analyze the effect of plaque symmetricity with a similar degree of stenosis (DOS) on plaque surface temperature and blood heat transfer in a straight vessel. This analysis aims towards predicting the severity of stenosis in a straight blood vessel through plaque temperature as an indicator. Two cases are being analyzed here; case 1 and case 2 refer to having similar vessel dimensions and an overall degree of stenosis (DOS) of 70%, with the exception of case 1 having a symmetrically developed plaque while case 2 refers to an asymmetrically developed plaque. Euler-Euler multiphase method with the applicati...
Source: Computer Methods in Biomechanics and Biomedical Engineering - April 2, 2024 Category: Biomedical Engineering Authors: Sidharth Sankar Das Swarup Kumar Mahapatra Source Type: research
Effect of blood viscosity on the hemodynamics of arteriovenous fistulae based on numerical investigation
Comput Methods Biomech Biomed Engin. 2024 Apr 2:1-13. doi: 10.1080/10255842.2024.2333926. Online ahead of print.ABSTRACTArteriovenous fistula (AVF) is the most commonly used vascular access for hemodialysis in patients with end-stage renal disease. Vascular diseases such as atherosclerosis and thrombosis, triggered by altered hemodynamic conditions, are the main causes of access failure. Changes in blood viscosity accelerate access dysfunction by affecting local velocities and wall shear stress (WSS) distribution in the circulation. Numerical simulation was employed to analyze and compare the hemodynamic behavior of AVF un...
Source: Computer Methods in Biomechanics and Biomedical Engineering - April 2, 2024 Category: Biomedical Engineering Authors: Ning Zhao Tian Zhang Tianyu Zhang Baohui Wang Weina Mu Fan Wang Source Type: research
Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease
In conclusion, the simulations suggest that time-averaged total stress along the fiber direction and time-averaged intracellular myofiber passive stress can be used to drive concentric and eccentric growth in simulations of valve disease.PMID:38564074 | DOI:10.1007/s10439-024-03497-x (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - April 2, 2024 Category: Biomedical Engineering Authors: Hossein Sharifi Mohammad Mehri Charles K Mann Kenneth S Campbell Lik Chuan Lee Jonathan F Wenk Source Type: research
Enhanced physiochemical, antibacterial, and hemostatic performance of collagen-quaternized chitosan-graphene oxide sponges for promoting infectious wound healing
This study provides new insights for developing innovative sponges for bacteria-infected wound healing.PMID:38565366 | DOI:10.1016/j.ijbiomac.2024.131277 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 2, 2024 Category: Biochemistry Authors: Zhiwei Sun Keqiang Hu Ting Wang Xiangru Chen Na Meng Ximing Peng Liya Ma Di Tian Shaotang Xiong Chuchao Zhou Yanqing Yang Source Type: research
Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease
In conclusion, the simulations suggest that time-averaged total stress along the fiber direction and time-averaged intracellular myofiber passive stress can be used to drive concentric and eccentric growth in simulations of valve disease.PMID:38564074 | DOI:10.1007/s10439-024-03497-x (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - April 2, 2024 Category: Biomedical Engineering Authors: Hossein Sharifi Mohammad Mehri Charles K Mann Kenneth S Campbell Lik Chuan Lee Jonathan F Wenk Source Type: research
Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease
In conclusion, the simulations suggest that time-averaged total stress along the fiber direction and time-averaged intracellular myofiber passive stress can be used to drive concentric and eccentric growth in simulations of valve disease.PMID:38564074 | DOI:10.1007/s10439-024-03497-x (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - April 2, 2024 Category: Biomedical Engineering Authors: Hossein Sharifi Mohammad Mehri Charles K Mann Kenneth S Campbell Lik Chuan Lee Jonathan F Wenk Source Type: research
Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease
In conclusion, the simulations suggest that time-averaged total stress along the fiber direction and time-averaged intracellular myofiber passive stress can be used to drive concentric and eccentric growth in simulations of valve disease.PMID:38564074 | DOI:10.1007/s10439-024-03497-x (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - April 2, 2024 Category: Biomedical Engineering Authors: Hossein Sharifi Mohammad Mehri Charles K Mann Kenneth S Campbell Lik Chuan Lee Jonathan F Wenk Source Type: research
Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease
In conclusion, the simulations suggest that time-averaged total stress along the fiber direction and time-averaged intracellular myofiber passive stress can be used to drive concentric and eccentric growth in simulations of valve disease.PMID:38564074 | DOI:10.1007/s10439-024-03497-x (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - April 2, 2024 Category: Biomedical Engineering Authors: Hossein Sharifi Mohammad Mehri Charles K Mann Kenneth S Campbell Lik Chuan Lee Jonathan F Wenk Source Type: research
A High Precision, Wide Dynamic Range Closed-Loop Neuromodulation IC With Rapid Stimulation Artifact Recovery
This article presents a high precision, wide dynamic range (DR) closed-loop neuromodulation (CLNM) system that can completely reject stimulation artifacts (SA) and achieve rapid SA recovery. In the recorder, a novel SA quick-blanking scheme is proposed for rail-to-rail SA rejection while minimizing SA recovery time. Besides, a new analog front-end (AFE) architecture based on a frequency-shaping (FS) technique is developed to extend DR intrinsically. In the stimulator, a stimulation driver implemented with a proposed redundant crossfire (RXF) technique is incorporated to improve the effective resolution of the stimulation c...
Source: IEEE Transactions on Biomedical Circuits and Systems - April 2, 2024 Category: Biomedical Engineering Source Type: research
A Direct Current-Sensing VCO-Based 2nd-Order Continuous-Time Sigma-Delta Modulator for Biosensor Readout Applications
A second-order voltage-controlled oscillator (VCO)-based continuous-time sigma-delta modulator (CTSDM) for current-sensing readout applications is proposed. Current signals from the sensor can directly be quantized by the proposed VCO-based CTSDM, which does not require any extra trans-impedance amplifiers. With the proportional-integral (PI) structure and a VCO phase integrator, the capability of second-order noise shaping is available to reduce the in-band quantization noise. The PI structure can be simply realized by a resistor in series with the integrating capacitor, which can reduce the architecture complexity and ma...
Source: IEEE Transactions on Biomedical Circuits and Systems - April 2, 2024 Category: Biomedical Engineering Source Type: research
Memristive Bionic Memory Circuit Implementation and Its Application in Multisensory Mutual Associative Learning Networks
Memory is vital and indispensable for organisms and brain-inspired intelligence to gain complete sensation and cognition of the environment. In this work, a memristive bionic memory circuit inspired by human memory model is proposed, which includes 1) receptor and sensory neuron (SN), 2) short-term memory (STM) module, and 3) long-term memory (LTM) module. By leveraging the in-memory computing characteristic of memristors, various functions such as sensation, learning, forgetting, recall, consolidation, reconsolidation, retrieval, and reset are realized. Besides, a multisensory mutual associative learning network is constr...
Source: IEEE Transactions on Biomedical Circuits and Systems - April 2, 2024 Category: Biomedical Engineering Source Type: research
Human Eye Activity Monitoring Using Continuous Wave Doppler Radar: A Feasibility Study
This article proposes a novel eye movement monitoring method called continuous wave doppler oculogram (cDOG). Unlike the conventional EOG-based eye movement monitoring methods, cDOG based on continuous wave doppler radar sensor (cDRS) can remotely measure human eye activity without placing electrodes on the head. To verify the feasibility of using cDOG for eye movement monitoring, we first theoretically analyzed the association between the radar signal and the corresponding eye movements measured with EOG. Afterward, we conducted an experiment to compare EOG and cDOG measurements under the conditions of eyes closure and op...
Source: IEEE Transactions on Biomedical Circuits and Systems - April 2, 2024 Category: Biomedical Engineering Source Type: research
Floating-Point Approximation Enabling Cost-Effective and High-Precision Digital Implementation of FitzHugh-Nagumo Neural Networks
The study of neuron interactions and hardware implementations are crucial research directions in neuroscience, particularly in developing large-scale biological neural networks. The FitzHugh-Nagumo (FHN) model is a popular neuron model with highly biological plausibility, but its complexity makes it difficult to apply at scale. This paper presents a cost-saving and improved precision approximation algorithm for the digital implementation of the FHN model. By converting the computational data into floating-point numbers, the original multiplication calculations are replaced by adding the floating-point exponent part and fit...
Source: IEEE Transactions on Biomedical Circuits and Systems - April 2, 2024 Category: Biomedical Engineering Source Type: research
On the accuracy of sequence methods for baroreflex sensitivity estimation
AbstractIn the absence of a true gold standard for non-invasive baroreflex sensitivity estimation, it is difficult to quantify the accuracy of the variety of techniques used. A popular family of methods, usually entitled ‘sequence methods’ involves the extraction of (apparently) correlated sequences from blood pressure and RR-interval data and the subsequent fitting of a regression line to the data. This paper discusses the accuracy of sequence methods from a system identification perspective, using both data ge nerated from a known mathematical model and spontaneous baroreflex data. It is shown that sequence methods c...
Source: Australasian Physical and Engineering Sciences in Medicine - April 2, 2024 Category: Biomedical Engineering Source Type: research
A deep learning framework for identifying and segmenting three vessels in fetal heart ultrasound images
Congenital heart disease (CHD) is one of the most common birth defects in the world. It is the leading cause of infant mortality, necessitating an early diagnosis for timely intervention. Prenatal screening us... (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - April 2, 2024 Category: Biomedical Engineering Authors: Laifa Yan, Shan Ling, Rongsong Mao, Haoran Xi and Fei Wang Tags: Research Source Type: research
