TriKSV-LG: a robust approach to disease prediction in healthcare systems using AI and Levy Gazelle optimization
Comput Methods Biomech Biomed Engin. 2024 Apr 30:1-17. doi: 10.1080/10255842.2024.2339479. Online ahead of print.ABSTRACTA seamless connection between the Internet and people is provided by the Internet of Things (IoT). Furthermore, lives are enhanced using the integration of the cloud layer. In the healthcare domain, a reactive healthcare strategy is turned into a proactive one using predictive analysis. The challenges faced by existing techniques are inaccurate prediction and a time-consuming process. This paper introduces an Artificial Intelligence (AI) and IoT-based disease prediction method, the TriKernel Support Vect...
Source: Computer Methods in Biomechanics and Biomedical Engineering - April 30, 2024 Category: Biomedical Engineering Authors: Kavitha Dhanushkodi Prema Vinayagasundaram Vidhya Anbalagan Surendran Subbaraj Ravikumar Sethuraman Source Type: research

Compression of EEG signals with the LSTM-autoencoder via domain adaptation approach
Comput Methods Biomech Biomed Engin. 2024 Apr 30:1-14. doi: 10.1080/10255842.2024.2346356. Online ahead of print.ABSTRACTThe successful implementation of neural network-based EEG signal compression has led to significant cost reductions in data transmission. However, a major obstacle in this process arises from the decline in performance when compressing EEG signals from multiple subjects. This challenge arises due to the notable feature shift of EEG signals between subjects, which poses an impediment to the neural network's efficient concurrent acquisition of information from multiple subjects. To address this limitation ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - April 30, 2024 Category: Biomedical Engineering Authors: Yongfei Liu Fan Yang Binbin Wu Source Type: research

Dual stress factors adaptive evolution for high EPA production in Schizochytrium sp. and metabolomics mechanism analysis
This study provides a novel pathway for promoting EPA biosynthesis in Schizochytrium.PMID:38687387 | DOI:10.1007/s00449-024-03013-4 (Source: Bioprocess and Biosystems Engineering)
Source: Bioprocess and Biosystems Engineering - April 30, 2024 Category: Biomedical Engineering Authors: Ying Ou Yu Qin Shoushuai Feng Hailin Yang Source Type: research

Controlled Mechanical Property Gradients Within a Digital Light Processing Printed Hydrogel-Composite Osteochondral Scaffold
Ann Biomed Eng. 2024 Apr 29. doi: 10.1007/s10439-024-03516-x. Online ahead of print.ABSTRACTTissue engineered scaffolds are needed to support physiological loads and emulate the micrometer-scale strain gradients within tissues that guide cell mechanobiological responses. We designed and fabricated micro-truss structures to possess spatially varying geometry and controlled stiffness gradients. Using a custom projection microstereolithography (μSLA) system, using digital light projection (DLP), and photopolymerizable poly(ethylene glycol) diacrylate (PEGDA) hydrogel monomers, three designs with feature sizes < 200 μm we...
Source: Annals of Biomedical Engineering - April 29, 2024 Category: Biomedical Engineering Authors: Kevin N Eckstein John E Hergert Asais Camila Uzcategui Sarah A Schoonraad Stephanie J Bryant Robert R McLeod Virginia L Ferguson Source Type: research

Low-Intensity Pulsed Ultrasound: A Physical Stimulus with Immunomodulatory and Anti-inflammatory Potential
Ann Biomed Eng. 2024 Apr 29. doi: 10.1007/s10439-024-03523-y. Online ahead of print.ABSTRACTUltrasound has expanded into the therapeutic field as a medical imaging and diagnostic technique. Low-intensity pulsed ultrasound (LIPUS) is a kind of therapeutic ultrasound that plays a vital role in promoting fracture healing, wound repair, immunomodulation, and reducing inflammation. Its anti-inflammatory effects are manifested by decreased pro-inflammatory cytokines and chemokines, accelerated regression of immune cell invasion, and accelerated damage repair. Although the anti-inflammatory mechanism of LIPUS is not very clear, m...
Source: Annals of Biomedical Engineering - April 29, 2024 Category: Biomedical Engineering Authors: Wenxin Liang Beibei Liang Kaicheng Yan Guanxuanzi Zhang Jiaju Zhuo Yun Cai Source Type: research

Controlled Mechanical Property Gradients Within a Digital Light Processing Printed Hydrogel-Composite Osteochondral Scaffold
Ann Biomed Eng. 2024 Apr 29. doi: 10.1007/s10439-024-03516-x. Online ahead of print.ABSTRACTTissue engineered scaffolds are needed to support physiological loads and emulate the micrometer-scale strain gradients within tissues that guide cell mechanobiological responses. We designed and fabricated micro-truss structures to possess spatially varying geometry and controlled stiffness gradients. Using a custom projection microstereolithography (μSLA) system, using digital light projection (DLP), and photopolymerizable poly(ethylene glycol) diacrylate (PEGDA) hydrogel monomers, three designs with feature sizes < 200 μm we...
Source: Annals of Biomedical Engineering - April 29, 2024 Category: Biomedical Engineering Authors: Kevin N Eckstein John E Hergert Asais Camila Uzcategui Sarah A Schoonraad Stephanie J Bryant Robert R McLeod Virginia L Ferguson Source Type: research

Low-Intensity Pulsed Ultrasound: A Physical Stimulus with Immunomodulatory and Anti-inflammatory Potential
Ann Biomed Eng. 2024 Apr 29. doi: 10.1007/s10439-024-03523-y. Online ahead of print.ABSTRACTUltrasound has expanded into the therapeutic field as a medical imaging and diagnostic technique. Low-intensity pulsed ultrasound (LIPUS) is a kind of therapeutic ultrasound that plays a vital role in promoting fracture healing, wound repair, immunomodulation, and reducing inflammation. Its anti-inflammatory effects are manifested by decreased pro-inflammatory cytokines and chemokines, accelerated regression of immune cell invasion, and accelerated damage repair. Although the anti-inflammatory mechanism of LIPUS is not very clear, m...
Source: Annals of Biomedical Engineering - April 29, 2024 Category: Biomedical Engineering Authors: Wenxin Liang Beibei Liang Kaicheng Yan Guanxuanzi Zhang Jiaju Zhuo Yun Cai Source Type: research

In Vitro and In Silico Characterization of the Aggregation of Thrombi on Textured Ventricular Cannula
Ann Biomed Eng. 2024 Apr 28. doi: 10.1007/s10439-024-03504-1. Online ahead of print.ABSTRACTThe unacceptably high stroke rate associated with HeartMate 3 ventricular assist device (VAD) without signs of adherent pump thrombosis is hypothesized to be the result of the emboli produced by the inflow cannula, that are ingested and ejected from the pump. This in vitro and numerical study aimed to emulate the surface features and supraphysiological shear of a ventricular cannula to provide insight into their effect on thrombogenesis. Human whole blood was perfused at calibrated flow rates in a microfluidic channel to achieve she...
Source: Annals of Biomedical Engineering - April 28, 2024 Category: Biomedical Engineering Authors: Wenxuan He Abhishek Karmakar Junhyuk Kang Grant Rowlands Samuel Schirmacher Rodrigo M éndez-Rojano James Antaki Source Type: research

In Vitro and In Silico Characterization of the Aggregation of Thrombi on Textured Ventricular Cannula
Ann Biomed Eng. 2024 Apr 28. doi: 10.1007/s10439-024-03504-1. Online ahead of print.ABSTRACTThe unacceptably high stroke rate associated with HeartMate 3 ventricular assist device (VAD) without signs of adherent pump thrombosis is hypothesized to be the result of the emboli produced by the inflow cannula, that are ingested and ejected from the pump. This in vitro and numerical study aimed to emulate the surface features and supraphysiological shear of a ventricular cannula to provide insight into their effect on thrombogenesis. Human whole blood was perfused at calibrated flow rates in a microfluidic channel to achieve she...
Source: Annals of Biomedical Engineering - April 28, 2024 Category: Biomedical Engineering Authors: Wenxuan He Abhishek Karmakar Junhyuk Kang Grant Rowlands Samuel Schirmacher Rodrigo M éndez-Rojano James Antaki Source Type: research

Promoting mechanism of nitrogen removal by Fe < sub > 3 < /sub > O < sub > 4 < /sub > magnetic particles during the start-up phase in sequencing batch reactor
Bioprocess Biosyst Eng. 2024 Apr 27. doi: 10.1007/s00449-024-03006-3. Online ahead of print.ABSTRACTIn this paper, a magnetic sequencing batch reactor (SBR) was constructed, and the influence rule of magnetic particle dosing performance of denitrification was investigated. The diversity, structure, and potential functions of the microbial community were comprehensively explored. The results showed that the particle size and the dosage of Fe3O4 magnetic particles were the main parameters affecting the sedimentation performance of activated sludge. The start-up phase of the SBR reactor with Fe3O4 magnetic particles was 5 day...
Source: Bioprocess and Biosystems Engineering - April 27, 2024 Category: Biomedical Engineering Authors: Xiaoyu Hu Shuai Zhang Guicai Liu Jiabin Wang Yue Wang Source Type: research

Identification of hyperthermophilic D-allulose 3-epimerase from Thermotoga sp. and its application as a high-performance biocatalyst for D-allulose synthesis
This study offers a promising resource for the enzyme engineering of DAEs and a high-performance biocatalyst for industrial D-allulose production.PMID:38676737 | DOI:10.1007/s00449-024-02989-3 (Source: Bioprocess and Biosystems Engineering)
Source: Bioprocess and Biosystems Engineering - April 27, 2024 Category: Biomedical Engineering Authors: Ji-Dong Shen Bao-Ping Xu Te-Li Yu Yong-Xiang Fei Xue Cai Liang-Gang Huang Li-Qun Jin Zhi-Qiang Liu Yu-Guo Zheng Source Type: research

Promoting mechanism of nitrogen removal by Fe < sub > 3 < /sub > O < sub > 4 < /sub > magnetic particles during the start-up phase in sequencing batch reactor
Bioprocess Biosyst Eng. 2024 Apr 27. doi: 10.1007/s00449-024-03006-3. Online ahead of print.ABSTRACTIn this paper, a magnetic sequencing batch reactor (SBR) was constructed, and the influence rule of magnetic particle dosing performance of denitrification was investigated. The diversity, structure, and potential functions of the microbial community were comprehensively explored. The results showed that the particle size and the dosage of Fe3O4 magnetic particles were the main parameters affecting the sedimentation performance of activated sludge. The start-up phase of the SBR reactor with Fe3O4 magnetic particles was 5 day...
Source: Bioprocess and Biosystems Engineering - April 27, 2024 Category: Biomedical Engineering Authors: Xiaoyu Hu Shuai Zhang Guicai Liu Jiabin Wang Yue Wang Source Type: research

Identification of hyperthermophilic D-allulose 3-epimerase from Thermotoga sp. and its application as a high-performance biocatalyst for D-allulose synthesis
This study offers a promising resource for the enzyme engineering of DAEs and a high-performance biocatalyst for industrial D-allulose production.PMID:38676737 | DOI:10.1007/s00449-024-02989-3 (Source: Bioprocess and Biosystems Engineering)
Source: Bioprocess and Biosystems Engineering - April 27, 2024 Category: Biomedical Engineering Authors: Ji-Dong Shen Bao-Ping Xu Te-Li Yu Yong-Xiang Fei Xue Cai Liang-Gang Huang Li-Qun Jin Zhi-Qiang Liu Yu-Guo Zheng Source Type: research

Women in engineering, science and technology in sub-Saharan Africa: cultural attitudes, challenges, and gaps affecting clinical engineering and medical devices maintenance practices
ConclusionsThere is an apparent need to further study the possible effects of this sociological model through leveraging local culture and domestic traditions in ways that could ultimately increase the leadership and numbers of women BMETs in SSA. (Source: Health and Technology)
Source: Health and Technology - April 26, 2024 Category: Information Technology Source Type: research