Evaluation of free and immobilized cellulase on chitosan-modified magnetic nanoparticles for saccharification of sorghum residue
Bioprocess Biosyst Eng. 2024 Apr 12. doi: 10.1007/s00449-024-03010-7. Online ahead of print.ABSTRACTEnzymatic hydrolysis plays a pivotal role in transforming lignocellulosic biomass. Addressing alternate techniques to optimize the utilization of cellulolytic enzymes is one strategy to improve its efficiency and lower process costs. Cellulases are highly specific and environmentally benign biocatalysts that break down intricate polysaccharides into simple forms of sugars. In contrast to the most difficult and time-consuming enzyme immobilization processes, in this research, we studied simple, mild, and successful techniques...
Source: Bioprocess and Biosystems Engineering - April 12, 2024 Category: Biomedical Engineering Authors: Pallavi Punia Lakhvinder Singh Source Type: research
Method for evaluating the fit of custom-fit Continuous Positive Airway Pressure masks using finite element analysis
Comput Methods Biomech Biomed Engin. 2024 Apr 12:1-18. doi: 10.1080/10255842.2024.2341120. Online ahead of print.ABSTRACTContinuous Positive Airway Pressure (CPAP) is a common therapy used to treat breathing disorders such as obstructive sleep apnea. In previous work, we designed a custom-fit CPAP mask to address comfort and leakage issues patients often experience. This paper presents a method to create a finite element (FE) model to evaluate the fit of the custom-fit mask before fabrication. The model includes details such as a skull to represent the variable soft tissue thicknesses on the face, and two strap configurati...
Source: Computer Methods in Biomechanics and Biomedical Engineering - April 12, 2024 Category: Biomedical Engineering Authors: Erica Martelly Sandeep Rana Kenji Shimada Source Type: research
Enhanced bactericidal, antibiofilm and antioxidative response of Lawsonia inermis leaf extract synthesized ZnO NPs loaded with commercial antibiotic
Bioprocess Biosyst Eng. 2024 Apr 12. doi: 10.1007/s00449-024-03000-9. Online ahead of print.ABSTRACTGlobally, antibiotic resistance is a challenging issue in healthcare sector. The emergence of multiple drug-resistant bacteria has forced us to modify existing medicines and or formulate newer medicines that are effective and inexpensive. In this perspective, this study involves the formation of zinc oxide nanoparticles (ZnO NPs) by utilizing the Lawsonia inermis (Li) leaf extract. The prepared L. inermis leaf extract mediated ZnO NPs (Li-ZnO NPs) were bio-physically characterized. The antibacterial and radical scavenging ef...
Source: Bioprocess and Biosystems Engineering - April 12, 2024 Category: Biomedical Engineering Authors: Balasubramanian Malaikozhundan Sonaimuthu Mohandoss Raman Krishnamoorthi Palanichamy Vidhya Bharathi Subramanian Palanisamy Jayaraj Vinodhini Source Type: research
Evaluation of free and immobilized cellulase on chitosan-modified magnetic nanoparticles for saccharification of sorghum residue
Bioprocess Biosyst Eng. 2024 Apr 12. doi: 10.1007/s00449-024-03010-7. Online ahead of print.ABSTRACTEnzymatic hydrolysis plays a pivotal role in transforming lignocellulosic biomass. Addressing alternate techniques to optimize the utilization of cellulolytic enzymes is one strategy to improve its efficiency and lower process costs. Cellulases are highly specific and environmentally benign biocatalysts that break down intricate polysaccharides into simple forms of sugars. In contrast to the most difficult and time-consuming enzyme immobilization processes, in this research, we studied simple, mild, and successful techniques...
Source: Bioprocess and Biosystems Engineering - April 12, 2024 Category: Biomedical Engineering Authors: Pallavi Punia Lakhvinder Singh Source Type: research
Enhanced bactericidal, antibiofilm and antioxidative response of Lawsonia inermis leaf extract synthesized ZnO NPs loaded with commercial antibiotic
Bioprocess Biosyst Eng. 2024 Apr 12. doi: 10.1007/s00449-024-03000-9. Online ahead of print.ABSTRACTGlobally, antibiotic resistance is a challenging issue in healthcare sector. The emergence of multiple drug-resistant bacteria has forced us to modify existing medicines and or formulate newer medicines that are effective and inexpensive. In this perspective, this study involves the formation of zinc oxide nanoparticles (ZnO NPs) by utilizing the Lawsonia inermis (Li) leaf extract. The prepared L. inermis leaf extract mediated ZnO NPs (Li-ZnO NPs) were bio-physically characterized. The antibacterial and radical scavenging ef...
Source: Bioprocess and Biosystems Engineering - April 12, 2024 Category: Biomedical Engineering Authors: Balasubramanian Malaikozhundan Sonaimuthu Mohandoss Raman Krishnamoorthi Palanichamy Vidhya Bharathi Subramanian Palanisamy Jayaraj Vinodhini Source Type: research
Evaluation of free and immobilized cellulase on chitosan-modified magnetic nanoparticles for saccharification of sorghum residue
Bioprocess Biosyst Eng. 2024 Apr 12. doi: 10.1007/s00449-024-03010-7. Online ahead of print.ABSTRACTEnzymatic hydrolysis plays a pivotal role in transforming lignocellulosic biomass. Addressing alternate techniques to optimize the utilization of cellulolytic enzymes is one strategy to improve its efficiency and lower process costs. Cellulases are highly specific and environmentally benign biocatalysts that break down intricate polysaccharides into simple forms of sugars. In contrast to the most difficult and time-consuming enzyme immobilization processes, in this research, we studied simple, mild, and successful techniques...
Source: Bioprocess and Biosystems Engineering - April 12, 2024 Category: Biomedical Engineering Authors: Pallavi Punia Lakhvinder Singh Source Type: research
Ultra-Sensitive Plasmonic Sensor for Detecting Honey Adulteration with III –V Nitride and Tungsten Disulfide
AbstractOwing to its phytochemical and antioxidant properties, honey has gained recognition as a therapeutic agent for various ailments, leading to its prominent role in the food industry. However, this popularity has also given rise to the significant problem of honey adulteration, posing a major challenge for the food industry. The present study explores the utilization of the wurtzite nitride semiconductor material, in combination with tungsten disulfide (WS2), within the surface plasmon resonance (SPR) sensor design for the detection of honey adulteration. The sensor ’s structure is based on the BK7 glass prism with ...
Source: Sensing and Imaging - April 12, 2024 Category: Biomedical Engineering Source Type: research
Source Enumeration Utilizing Adaptive Diagonal Loading and Linear Shrinkage Coefficients
Source enumeration is typically studied under the assumption of white noise, which may not be suitable for real-world applications. In this article, a source enumeration algorithm robust against both white and colored noises is presented, where the adaptive diagonal loading (ADL) technique combined with linear shrinkage (LS) coefficients are employed. First, a proper loading level is adaptively determined under the presumed number of sources $v$, which is then applied to mitigate correlated and heterogeneous noise, and simultaneously yields an encouraging result that the loaded eigenvalues match the asymptotic ratio behavi...
Source: IEEE Transactions on Signal Processing - April 11, 2024 Category: Biomedical Engineering Source Type: research
Modelling the extracellular potential generated by a muscle fiber as the output signal of a convolutional system
Adv Physiol Educ. 2024 Apr 11. doi: 10.1152/advan.00238.2023. Online ahead of print.ABSTRACTA central topic in Bioelectricity is the generation of the extracellular potential that results from the propagation of a transmembrane action potential along the muscle fiber. However, the way in which the extracellular potential is determined by the propagating action potential is difficult to describe, conceptualize and visualize. Moreover, traditional quantitative approaches aimed at modelling extracellular potentials involve complex mathematical formulations, which do not allow students to visualize how the extracellular potent...
Source: Adv Physiol Educ - April 11, 2024 Category: Universities & Medical Training Authors: Javier Rodriguez-Falces Source Type: research
Modelling the extracellular potential generated by a muscle fiber as the output signal of a convolutional system
Adv Physiol Educ. 2024 Apr 11. doi: 10.1152/advan.00238.2023. Online ahead of print.ABSTRACTA central topic in Bioelectricity is the generation of the extracellular potential that results from the propagation of a transmembrane action potential along the muscle fiber. However, the way in which the extracellular potential is determined by the propagating action potential is difficult to describe, conceptualize and visualize. Moreover, traditional quantitative approaches aimed at modelling extracellular potentials involve complex mathematical formulations, which do not allow students to visualize how the extracellular potent...
Source: Advances in Physiology Education - April 11, 2024 Category: Physiology Authors: Javier Rodriguez-Falces Source Type: research
Prediction of rhinitis with class imbalance based on heterogeneous ensemble learning
Comput Methods Biomech Biomed Engin. 2024 Apr 11:1-16. doi: 10.1080/10255842.2024.2339461. Online ahead of print.ABSTRACTCommon clinical rhinitis is characterized by different types of cases and class imbalance. Its prediction belongs to multiple output classification. Low recognition rate and poor generalization performance often occur for minority class. Therefore, we propose a novel integrated classification model, ARF-OOBEE, which transforms the multi-output classification to multi-label classification and multi-class classification. The multi-label classifier automatically adjusts the number and depth of integrated fo...
Source: Computer Methods in Biomechanics and Biomedical Engineering - April 11, 2024 Category: Biomedical Engineering Authors: Jingdong Yang Biao Jiang Zehao Qiu Yifei Meng Xiaolin Zhang Shaoqing Yu Fu Dai Yue Qian Source Type: research
Ethical Considerations of Neuralink and Brain-Computer Interfaces: Balancing Innovation and Responsibility
Ann Biomed Eng. 2024 Apr 11. doi: 10.1007/s10439-024-03511-2. Online ahead of print.ABSTRACTNeuralink is a neurotechnology company founded by Elon Musk in 2016, which has been quietly developing revolutionary technology allowing for ultra-high precision bidirectional communication between external devices and the brain. In this paper, we explore the multifaceted ethical considerations surrounding neural interfaces, analyzing potential societal impacts, risks, and call for a need for responsible innovation. Despite the technological, medical, medicolegal, and ethical challenges ahead, neural interface technology remains ext...
Source: Annals of Biomedical Engineering - April 11, 2024 Category: Biomedical Engineering Authors: Ethan Waisberg Joshua Ong Andrew G Lee Source Type: research
Modelling the extracellular potential generated by a muscle fiber as the output signal of a convolutional system
Adv Physiol Educ. 2024 Apr 11. doi: 10.1152/advan.00238.2023. Online ahead of print.ABSTRACTA central topic in Bioelectricity is the generation of the extracellular potential that results from the propagation of a transmembrane action potential along the muscle fiber. However, the way in which the extracellular potential is determined by the propagating action potential is difficult to describe, conceptualize and visualize. Moreover, traditional quantitative approaches aimed at modelling extracellular potentials involve complex mathematical formulations, which do not allow students to visualize how the extracellular potent...
Source: Adv Physiol Educ - April 11, 2024 Category: Universities & Medical Training Authors: Javier Rodriguez-Falces Source Type: research
Modelling the extracellular potential generated by a muscle fiber as the output signal of a convolutional system
Adv Physiol Educ. 2024 Apr 11. doi: 10.1152/advan.00238.2023. Online ahead of print.ABSTRACTA central topic in Bioelectricity is the generation of the extracellular potential that results from the propagation of a transmembrane action potential along the muscle fiber. However, the way in which the extracellular potential is determined by the propagating action potential is difficult to describe, conceptualize and visualize. Moreover, traditional quantitative approaches aimed at modelling extracellular potentials involve complex mathematical formulations, which do not allow students to visualize how the extracellular potent...
Source: Advances in Physiology Education - April 11, 2024 Category: Physiology Authors: Javier Rodriguez-Falces Source Type: research
Prediction of rhinitis with class imbalance based on heterogeneous ensemble learning
Comput Methods Biomech Biomed Engin. 2024 Apr 11:1-16. doi: 10.1080/10255842.2024.2339461. Online ahead of print.ABSTRACTCommon clinical rhinitis is characterized by different types of cases and class imbalance. Its prediction belongs to multiple output classification. Low recognition rate and poor generalization performance often occur for minority class. Therefore, we propose a novel integrated classification model, ARF-OOBEE, which transforms the multi-output classification to multi-label classification and multi-class classification. The multi-label classifier automatically adjusts the number and depth of integrated fo...
Source: Computer Methods in Biomechanics and Biomedical Engineering - April 11, 2024 Category: Biomedical Engineering Authors: Jingdong Yang Biao Jiang Zehao Qiu Yifei Meng Xiaolin Zhang Shaoqing Yu Fu Dai Yue Qian Source Type: research
