The cushioning function of woodpecker's jaw apparatus during the pecking process.
This study discovered that the jaw apparatus acted as a cushion during the pecking process and the quadrate bone and joints changed the type of load and prolonged the acting time, which reduced the impact load acted on the skull and brain. This study would provide new inspirations to develop the device for brain protection, bio-inspired structure and material for energy-absorbing. PMID: 33439040 [PubMed - as supplied by publisher] (Source: Computer Methods in Biomechanics and Biomedical Engineering)
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 13, 2021 Category: Biomedical Engineering Authors: Xu P, Ni Y, Lu S, Liu S, Zhou X, Fan Y Tags: Comput Methods Biomech Biomed Engin Source Type: research

Design optimization of implant geometrical characteristics enhancing primary stability using FEA of stress distribution around dental prosthesis.
This study is helpful in choosing the optimal dental implant for clinical application. PMID: 33439043 [PubMed - as supplied by publisher] (Source: Computer Methods in Biomechanics and Biomedical Engineering)
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 13, 2021 Category: Biomedical Engineering Authors: Elleuch S, Jrad H, Kessentini A, Wali M, Dammak F Tags: Comput Methods Biomech Biomed Engin Source Type: research

Are college campuses superspreaders? A data-driven modeling study.
Abstract The COVID-19 pandemic continues to present enormous challenges for colleges and universities and strategies for save reopening remain a topic of ongoing debate. Many institutions that reopened cautiously in the fall experienced a massive wave of infections and colleges were soon declared as the new hotspots of the pandemic. However, the precise effects of college outbreaks on their immediate neighborhood remain largely unknown. Here we show that the first two weeks of instruction present a high-risk period for campus outbreaks and that these outbreaks tend to spread into the neighboring communities. By in...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 13, 2021 Category: Biomedical Engineering Authors: Lu H, Weintz C, Pace J, Indana D, Linka K, Kuhl E Tags: Comput Methods Biomech Biomed Engin Source Type: research

Wavelet-based semblance analysis to determine muscle synergy for different handstand postures of Chilean circus athletes.
The objective of this study was to determine the muscle synergy of four handstand postures through a semblance analysis based on wavelets of electromyographic signals in the upper limbs of experienced circus performers between 18- and 35-year old. The results show that there is a large difference in positive and negative correlations depending on the posture, which suggests that the more asymmetrical the position of the lower limbs, the greater the number of strategies to maintain the posture. Although it is not a statistically significant data, it is observed that the posture 3 in particular, possesses the greatest number...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 11, 2021 Category: Biomedical Engineering Authors: Calderón-Díaz M, Ulloa-Jiménez R, Saavedra C, Salas R Tags: Comput Methods Biomech Biomed Engin Source Type: research

Effect of simulated sensorimotor noise on kinematic variability and stability of a biped walking model.
Abstract Whether higher variability in older adults' walking is an indication of increased instability has been challenged recently. We performed a computer simulation to investigate the effect of sensorimotor noise on the kinematic variability and stability in a biped walking model. Stochastic differential equations of the system with additive Gaussian white noise was constructed and solved. Sensorimotor noise mainly resulted in higher kinematic variability but its influence on gait stability is minimal. This implies that kinematic variability evident in walking gaits of older adults could be the result of intern...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 11, 2021 Category: Biomedical Engineering Authors: Mehdizadeh S, Glazier PS Tags: Comput Methods Biomech Biomed Engin Source Type: research

Multi disease-prediction framework using hybrid deep learning: an optimal prediction model.
Abstract Big data and its approaches are generally helpful for healthcare and biomedical sectors for predicting the disease. For trivial symptoms, the difficulty is to meet the doctors at any time in the hospital. Thus, big data provides essential data regarding the diseases on the basis of the patient's symptoms. For several medical organizations, disease prediction is important for making the best feasible health care decisions. Conversely, the conventional medical care model offers input as structured that requires more accurate and consistent prediction. This paper is planned to develop the multi-disease predi...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 11, 2021 Category: Biomedical Engineering Authors: Ampavathi A, Saradhi TV Tags: Comput Methods Biomech Biomed Engin Source Type: research

Mathematical modeling of the Fontan blood circulation supported with pediatric ventricular assist device.
Abstract The decompensated univentricular circulation is identified as one of the most challenging conditions and the application of the mechanical circulatory support (MCS) devices is proposed as therapeutic option for Fontan failure. Modelling methodologies are reported to identify the optimized types, extent and duration of required hemodynamic support using MCS. The specific parameters of device-body interaction during support of failing Fontan circulation within the design points of dedicated pediatric ventricular assist devices has not been previously defined. In this work, we introduce a mathematical model ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 11, 2021 Category: Biomedical Engineering Authors: Rubtsova E, Markov A, Selishchev S, Karimov JH, Telyshev D Tags: Comput Methods Biomech Biomed Engin Source Type: research

BOPS: a Matlab toolbox to batch musculoskeletal data processing for OpenSim.
Abstract This paper presents Batch OpenSim Processing Scripts (BOPS), a Matlab toolbox for batch processing common OpenSim procedures: Inverse Kinematics, Inverse Dynamics, Muscle Analysis, Static Optimization, and Joint Reaction Analysis. BOPS is an easy-to-use and highly configurable tool that aims to reduce the time required to process large datasets, thus fostering the adoption of musculoskeletal modeling and simulations in daily practice. Its graphical user interface includes pre-defined setup files and has been designed to fulfill the needs of different research projects by simplifying the customization of t...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 11, 2021 Category: Biomedical Engineering Authors: Bedo BLS, Mantoan A, Catelli DS, Cruaud W, Reggiani M, Lamontagne M Tags: Comput Methods Biomech Biomed Engin Source Type: research

New approach of controlling the area affected in brain tumour treatment by LITT.
The objective of this paper is to present an approach to control the temperature distribution and heat affected zone in brain tumours when irradiated by shielded laser beam, 1064 nm ND-YAG. The effects of laser beam, resulting in tissue temperature increasing, follows the border of tumour by defining of a dual intensity distribution. This is included two distinct intensity distributions of laser on the applicator by shielding. Treatment of an arbitrary topology of tumour will be simulated irradiation of laser by two different distributions through numerical method. Results show when dual distribution on the tumour b...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 11, 2021 Category: Biomedical Engineering Authors: Amini S, Ahmadikia H Tags: Comput Methods Biomech Biomed Engin Source Type: research

The biomechanical effects of Ti versus PEEK used in the PLIF surgery on lumbar spine: a finite element analysis.
Abstract Titanium (Ti) and polyetheretherketone (PEEK) are commonly used in posterior lumbar interbody fusion (PLIF). The study investigated biomechanical effects of Ti versus PEEK used as materials of cage and rods on the lumbar spine. Four different configurations of PLIF were constituted. Stiff Ti rods provided satisfactory initial stability but increased the stress on rods significantly under simulated physiological load conditions. Ti cage increased the stress on bone endplates significantly. Materials of cage and rods had insignificant effects on the nucleus pressure and facet joint force of non-instrumented...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 11, 2021 Category: Biomedical Engineering Authors: Wang H, Wan Y, Liu X, Ren B, Xia Y, Liu Z Tags: Comput Methods Biomech Biomed Engin Source Type: research

Development and evaluation of a new procedure for subject-specific tensioning of finite element knee ligaments.
This study is the first step toward the use of simplified, personalized knee FE models in clinical context such as ligament balancing. PMID: 33427509 [PubMed - as supplied by publisher] (Source: Computer Methods in Biomechanics and Biomedical Engineering)
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 11, 2021 Category: Biomedical Engineering Authors: Lahkar BK, Rohan PY, Pillet H, Thoreux P, Skalli W Tags: Comput Methods Biomech Biomed Engin Source Type: research

Modeling of muscular activation of the muscle-tendon complex using discrete element method.
Abstract The tearing of a muscle-tendon complex (MTC) is caused by an eccentric contraction; however, the structures involved and the mechanisms of rupture are not clearly identified. The passive mechanical behavior the MTC has already been modeled and validated with the discrete element method. The muscular activation is the next needed step. The aim of this study is to model the muscle fiber activation and the muscular activation of the MTC to validate their active mechanical behaviors. Each point of the force/length relationship of the MTC (using a parabolic law for the force/length relationship of muscle fiber...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 8, 2021 Category: Biomedical Engineering Authors: Roux A, Lecompte J, Iordanoff I, Laporte S Tags: Comput Methods Biomech Biomed Engin Source Type: research

Influence of gap distance between bone and plate on structural stiffness and parallel interfragmental movement in far-cortical locking technique - a biomechanical study.
Abstract Sufficient interfragmental movement is the key to successful fracture healing in the theory of secondary bone healing. The far-cortical locking technique enables both stiffness reduction and parallel motion for ideal callus formation and fracture healing, but the influence of plate-bone gap on the performance of far-cortical locking technique remains unclear. The current study conducted a series of finite element analyses with mechanical validation to clarify this issue. Plate-bone gaps were assigned by 1, 2, 3, and 4 mm in a simulated mid-shaft fracture model fixed with locking plate and six semi-...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 7, 2021 Category: Biomedical Engineering Authors: Feng YJ, Lin KP, Tsai CL, Wei HW Tags: Comput Methods Biomech Biomed Engin Source Type: research

Does overlay preparation design affect polymerization shrinkage stress distribution? A 3D FEA study.
This study evaluated the polymerization shrinkage stress of three tooth preparation designs for indirect ceramic overlay by finite element analysis: isthmus preparation (IST); without isthmus preparation (wIST); and non-retentive preparation (nRET). The models were created based in prepared dental typodonts and were digitally impressed with an intraoral scanner. The interfaces in all models were considered perfectly bonded and all materials were considered homogeneous, linear, and isotropic. The polymerization shrinkage of the cement layer (100 µm) was simulated and evaluated by maximum principal stress criter...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 7, 2021 Category: Biomedical Engineering Authors: de Andrade GS, Pinto ABA, Tribst JPM, Chun EP, Borges ALS, de Siqueira Ferreira Anzaloni Saavedra G Tags: Comput Methods Biomech Biomed Engin Source Type: research

Transport and deposition of ultrafine particles in the upper tracheobronchial tree: a comparative study between approximate and realistic respiratory tract models.
Abstract This paper presents a computational fluid dynamics (CFD) study of air-particle flows in the upper tracheobronchial tree. Two respiratory tract models, including a parametrically controlled approximate airway model developed by Kitaoka (KG model) and a CT-based patient specific airway (realistic model) were used. Assuming laminar, quasi-steady, three-dimensional air flow and spherical non-interacting ultrafine particles in sequentially bifurcating rigid bronchial airways, airflow patterns and particle transport/deposition in these two airway models were evaluated and compared. Overall deposition efficiency...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 7, 2021 Category: Biomedical Engineering Authors: Dong J, Li J, Tian L, Tu J Tags: Comput Methods Biomech Biomed Engin Source Type: research

On the functional connectivity between heart, muscle, and frontal brain cortex during exercise fatigability.
rez D Abstract We analyze the functional connectivity of the cortico-cardiac-muscular network during muscle fatigability due to exercise. For our experiments, we recruited ten volunteers who performed two cycling routines. Our volunteers were classified according to physical activity level as active or sedentary. First, we measured the electromyography (EMG) signal of the vastus lateralis muscle to find the volunteer's individualized physical workload capacity at the fatigue threshold. Two to three days later, we measured the volunteers' EMG, electrocardiography, and electroencephalography (EEG) data during the de...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 6, 2021 Category: Biomedical Engineering Authors: Pichardo-Rivas KA, Gutiérrez D Tags: Comput Methods Biomech Biomed Engin Source Type: research

Propagation of registration errors into the change in maximum total point motion for determining stability of tibial baseplates.
Abstract The change in maximum total point motion (ΔMTPM) is used to predict long-term risk of tibial baseplate loosening, however, effects of registration error on ΔMTPM have not been quantified for marker-based and model-based radiostereometric analysis (RSA). Registration errors for marker-based and model-based RSA were applied to a stable tibial baseplate in MATLAB simulations to determine the bias and precision in ΔMTPM and the proportions of baseplates which fell above the continuous migration stability limit. No bias error occurred, however, the precision of ΔMTPM was twice as large ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 5, 2021 Category: Biomedical Engineering Authors: Niesen AE, Hull ML Tags: Comput Methods Biomech Biomed Engin Source Type: research

A comparative finite element simulation of locking compression plate materials for tibial fracture treatment.
This study was therefore aimed at investigate the biomechanical performance of the internal tibial locked plates at different material properties, including SS, Ti, carbon/polyether ether ketone (PEEK) composite, in treating medial tibial fracture using patient-specific finite element (FE) model of the human tibia. The carbon/PEEK composite materials were used at three different fiber plies configurations. Simulated loading was applied at 60:40 ratios on the medial:lateral aspect. The model was fixed distally in all degrees of freedom. The results revealed the highest stress (307.10 MPa) and the lowest strain (0.14%...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 4, 2021 Category: Biomedical Engineering Authors: Beirami S, Nikkhoo M, Hassani K, Karimi A Tags: Comput Methods Biomech Biomed Engin Source Type: research

Biomechanical analysis of reinstating buccally flared maxillary 2nd molars using 3D printing anchorage supports: a 3D finite element study.
The objectives of this study were to design anchorage systems to correct buccally flared maxillary 2nd molars and analyze their biomechanical effects by 3-dimensional (3D) finite element analysis. Finite element (FE) models of the 3D tanspalatal arches (TPAs) and 3D splints with different thicknesses and force points were constructed. The stress distribution on teeth, the hydrostatic pressure on periodontal ligaments and the initial displacement of teeth were analyzed. A total of 18 FE models were constructed and analyzed. The stress concentrated on a single anchorage tooth, and the hydrostatic pressure and initial displac...
Source: Computer Methods in Biomechanics and Biomedical Engineering - January 4, 2021 Category: Biomedical Engineering Authors: Kuang Y, Wang C, Hu B, Feng G, Wang C, Song J Tags: Comput Methods Biomech Biomed Engin Source Type: research

Classification of forearm EMG signals for 10 motions using optimum feature-channel combinations.
Abstract Electromyography (EMG) is the study of electrical activity in the muscles. We classify EMG signals from surface electrodes (channels) using Artificial Neural Network (ANN). We evaluate classification performance of 10 different hand motions using several feature-channel combinations with wrapper method. Highest classification accuracy of 98.7% is achieved with each feature-channel combination. Compared to previous studies, we achieve the highest accuracy for 10 classes with lower number of feature-channel combination. We reduce ANN complexity without compromising the classification accuracy for deployment...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 27, 2020 Category: Biomedical Engineering Authors: Shahzaib M, Shakil S, Ghuffar S, Maqsood M, Bhatti FA Tags: Comput Methods Biomech Biomed Engin Source Type: research

PyTHang: an open-source wearable sensor system for real-time monitoring of head-torso angle for ambulatory applications.
This article presents the realization of a low-cost wearable sensor system and its Python-based software that can measure and record relative head-torso angle, especially in sagittal plane. The system is mainly developed to track head-torso angle during walk in a clinical study. The open-hardware part of the system is composed of a pair of triaxial digital accelerometers, a microprocessor, a Bluetooth module and a rechargeable battery unit. The reception of the transmitted acceleration data, visualization, interactive sensor alignment, angle estimation and data-logging are realized by the developed open-source graphical us...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 27, 2020 Category: Biomedical Engineering Authors: Gürkan G Tags: Comput Methods Biomech Biomed Engin Source Type: research

Development of a musculoskeletal model of the wrist to predict frictional work dissipated due to tendon gliding resistance in the carpal tunnel.
Abstract Carpal tunnel syndrome is an entrapment neuropathy that has been associated with the aggravation of tendon gliding resistance due to forceful, high velocity, awkwardly angled, and repetitive wrist motions. Cadaveric and epidemiological studies have shown that combinations of these risk factors have a more than additive effect. The aim of the current study was to develop a musculoskeletal model of the wrist that could evaluate these risk factors by simulating frictional work dissipated due to the gliding resistance of the third flexor digitorum superficialis tendon. Three flexion angle zones, three extensi...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 27, 2020 Category: Biomedical Engineering Authors: Glenday JD, Steinhilber B, Jung F, Haeufle DFB Tags: Comput Methods Biomech Biomed Engin Source Type: research

Classification of the mechanism of toxicity as applied to human cell line ECV304.
The objective of this study was to identify the pattern of cytotoxicity testing of the human cell line ECV304 using three techniques of an ensemble learning algorithm (bagging, boosting and stacking). The study of cell morphology of ECV304 cell line was conducted using impedimetric measurement. Three types of toxins were applied to the ECV304 cell line namely 1 mM hydrogen peroxide (H2O2), 5% dimethyl sulfoxide and 10 μg Saponin. The measurement was conducted using electrodes and lock-in amplifier to detect impedance changes during cytotoxicity testing within a frequency range 200 and 830 kHz. The r...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 27, 2020 Category: Biomedical Engineering Authors: Djawad YA, Kiely J, Luxton R Tags: Comput Methods Biomech Biomed Engin Source Type: research

On the molecular structure of Remdesivir for the treatment of Covid-19.
Abstract (SARS-CoV-2), was first identified in December 2019 as the cause of a respiratory illness designated coronavirus disease 2019, or Covid-19. Several therapeutic agents have been evaluated for the treatment of Covid-19, but none have yet been shown to be efficacious. Remdesivir (GS-5734), an inhibitor of the viral RNA-dependent, RNA polymerase with inhibitory activity against SARS-CoV and the Middle East respiratory syndrome (MERS-CoV), was identified early as a promising therapeutic candidate for Covid-19 because of its ability to inhibit SARS-CoV-2 in vitro. Besides, in nonhuman primate studies, remd...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 27, 2020 Category: Biomedical Engineering Authors: Sheikholeslami SM, Jahanbani A, Shao Z Tags: Comput Methods Biomech Biomed Engin Source Type: research

Biomechanical evaluation of the stability of extra-articular distal radius fractures fixed with volar locking plates according to the length of the distal locking screw.
Abstract Surgeons usually used short screws to avoid extensor tendon problems during volar locking plate fixation in distal radius fracture. However, the stability according to the length of distal locking screws have not been fully understood. We investigated this issue through finite element analysis and compression test using synthetic radius. Our results demonstrated that the bi-cortical full-length fixation does not contribute to the stiffness increase in the axial compression direction, and a reduction in length of up to more than 50% length can still provide similar stability to full-length screws. Our data...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 21, 2020 Category: Biomedical Engineering Authors: Oh GH, Kim HS, Lee JI Tags: Comput Methods Biomech Biomed Engin Source Type: research

Varying speed modulation of continuous-flow left ventricular assist device based on cardiovascular coupling numerical model.
This study provides valuable insight for further optimization of varying speed modulation by weighing vascular pulsatility, ventricular unloading, and hemodynamics. PMID: 33347766 [PubMed - as supplied by publisher] (Source: Computer Methods in Biomechanics and Biomedical Engineering)
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 21, 2020 Category: Biomedical Engineering Authors: Liu H, Liu S, Ma X Tags: Comput Methods Biomech Biomed Engin Source Type: research

Analysis of the relationship between hip joint flexion/extension and torques in the mark III space suit using a computational dynamics model.
Abstract Advanced SSAs (e.g., the Mark III (MKIII)) were designed to increase mobility by eliminating the volume change associated with bending joints by using constant-volume rigid components with bearings connecting these components. Even with these changes, there are added torques required by the operator to drive the motion, which increases the energy expenditure with respect to unsuited motion. Part of the added effort stems from the mass and inertia of the suit, as well as frictional resistances to motion. This research considers the relationship between joint torques that an operator must generate and the r...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 18, 2020 Category: Biomedical Engineering Authors: McKeen P, Cullinane C, Rhodes R, Stirling L Tags: Comput Methods Biomech Biomed Engin Source Type: research

Accurate simulation of the herniated cervical intervertebral disc using controllable expansion: a finite element study.
Abstract Expansions were carried out in finite element (FE) models of disc hernia including symmetric (median, lateral, paramedian) and asymmetric types. In all models, lubricous disk bulging that applied a linear compression to the anterior part of the cord was observed at the posterior surfaces of the expansion zone, respectively. The shape and position of protrusions varyed with the temperature, magnitude, and location of expanding elements. The geometric deformation and stress distribution of the spinal cord increased as the extent of compression grew. This method is in possession of enormous potential in prom...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 17, 2020 Category: Biomedical Engineering Authors: Liang D, Tu GJ, Han YX, Guo DW Tags: Comput Methods Biomech Biomed Engin Source Type: research

Finite element method based parametric study of Gastrocnemius-soleus recession: implications to the treatment of midfoot-forefoot overload syndrome.
The objective of this study was to conduct a parametric study to quantify the relationship between the level of recession and plantar fascia stress. A finite element model of the foot-ankle-shank complex was reconstructed from magnetic resonance and computed tomography images of a 63-year-old normal female. The model was validated by comparing modeled stresses to the measured plantar pressure distribution of the model participant during balanced standing. The midstance and push-off instants of walking stance were simulated with different levels and combinations of gastrocnemius-soleus recession resembled by different amoun...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 15, 2020 Category: Biomedical Engineering Authors: Lv ML, Zhang H, Chen L, Liu Y, Wang F, Wong DW, Sun L, Ni M Tags: Comput Methods Biomech Biomed Engin Source Type: research

Numerical study of hemodynamics in a complete coronary bypass with venous and arterial grafts and different degrees of stenosis.
Abstract Cardiovascular diseases are among the leading causes of death in the world. The coronary blockage is one of most common types of these diseases that in the majority of cases has been treated by bypass surgery. In the bypass surgery, a graft is implemented to alter the blocked coronary and allow the blood supply process. The hemodynamic characteristics of the bypass strongly depend on the geometry and mechanical properties of the graft. In the present study, the fluid-structure interaction (FSI) analysis is conducted to investigate the bypass performance for a thoracic artery as well as a saphenous vein gr...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 12, 2020 Category: Biomedical Engineering Authors: Alizadehghobadi S, Biglari H, Niroomand-Oscuii H, Matin MH Tags: Comput Methods Biomech Biomed Engin Source Type: research

The biomechanical characteristics of human vestibular aqueduct: a numerical-based model construction and simulation.
In this study, the vestibular aqueduct images obtained by CT scanning were processed by finite element method to construct the 3D model. To assess if this numerical model reflects the actual biomechanical properties of vestibular aqueduct, the fluid-solid coupling calculation was applied to simulate the endolymphatic flow in the vestibular aqueduct. By measuring the dynamics of endolymphatic flow, and the pressure and displacement on round membrane under external pressure, we found the numerical 3D model recapitulated the biomechanical characteristics of the real vestibular aqueduct. In summary, our approach of 3D model co...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 11, 2020 Category: Biomedical Engineering Authors: Guan Q, Sun D, Zhao M, Liu Y, Yu S, Zhang J, Li R, Sun K, Sun X, Bie X Tags: Comput Methods Biomech Biomed Engin Source Type: research

Design and fluid flow simulation of modified laparoscopic forceps.
Abstract Laparoscopic surgery has gained prominence in recent decades and employed in minimally invasive surgeries to avoid massive cuts resulting in a reduction in pain, the chance of infection, and duration of stay in the hospital. Maryland forceps, which belongs to the category of grasper instruments, are often used in minimally invasive surgeries to hold, pull, push, manipulate, and perform dissection operations. During laparoscopic surgeries, often blood and other body fluids ooze from the site of surgery. Typically, suction-irrigation (SI) devices are used to periodically clear these fluids to get a better v...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 11, 2020 Category: Biomedical Engineering Authors: Junaidi MAR, Kalluri RCM, Rao YVD, Gokhale AGK, Patel A Tags: Comput Methods Biomech Biomed Engin Source Type: research

A new musculoskeletal AnyBody ™ detailed hand model.
A new musculoskeletal AnyBody™ detailed hand model. Comput Methods Biomech Biomed Engin. 2020 Dec 10;:1-11 Authors: Engelhardt L, Melzner M, Havelkova L, Fiala P, Christen P, Dendorfer S, Simon U Abstract Musculoskeletal research questions regarding the prevention or rehabilitation of the hand can be addressed using inverse dynamics simulations when experiments are not possible. To date, no complete human hand model implemented in a holistic human body model has been fully developed. The aim of this work was to develop, implement, and validate a fully detailed hand model using the AnyBody Modell...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 10, 2020 Category: Biomedical Engineering Authors: Engelhardt L, Melzner M, Havelkova L, Fiala P, Christen P, Dendorfer S, Simon U Tags: Comput Methods Biomech Biomed Engin Source Type: research

Towards a predictive simulation of brace action in adolescent idiopathic scoliosis.
Abstract Bracing is the most common treatment to stop the progression of adolescent idiopathic scoliosis. Finite element modeling could help improve brace design, but model validation is still a challenge. In this work, the clinical relevance of a predictive and subject-specific model for bracing was evaluated in forty-six AIS patients. The model reproduces brace action and the patient's spinopelvic adjustments to keep balance. The model simulated 70% or more patients with geometrical parameters within a preselected tolerance level. Although the model simulation of the sagittal plane could be improved, the approac...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 9, 2020 Category: Biomedical Engineering Authors: Vergari C, Chen Z, Robichon L, Courtois I, Ebermeyer E, Vialle R, Langlais T, Pietton R, Skalli W Tags: Comput Methods Biomech Biomed Engin Source Type: research

Continuum modeling for neuronal lamination during cerebral morphogenesis considering cell migration and tissue growth.
Abstract For neuronal lamination during cerebral morphogenesis, later-born neurons must migrate through already-accumulated neurons. This neuronal migration is biochemically regulated by signaling molecules and mechanically affected by tissue deformation. To understand the neuronal lamination mechanisms, we constructed a continuum model of neuronal migration in a growing deformable tissue. We performed numerical analyses considering the migration promoted by signaling molecules and the tissue growth induced by neuron accumulation. The results suggest that the promoted migration and the space ensured by tissue grow...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 8, 2020 Category: Biomedical Engineering Authors: Takeda H, Kameo Y, Adachi T Tags: Comput Methods Biomech Biomed Engin Source Type: research

Artificial Intelligence-Assisted motion capture for medical applications: a comparative study between markerless and passive marker motion capture.
Abstract We aimed to determine whether artificial intelligence (AI)-assisted markerless motion capture software is useful in the clinical medicine and rehabilitation fields. Currently, it is unclear whether the AI-assisted markerless method can be applied to individuals with lower limb dysfunction, such as those using an ankle foot orthosis or a crutch. However, as many patients with lower limb paralysis and foot orthosis users lose metatarsophalangeal (MP) joint flexion during the stance phase, it is necessary to estimate the accuracy of foot recognition under fixed MP joint motion. The hip, knee, and ankle joint...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 8, 2020 Category: Biomedical Engineering Authors: Takeda I, Yamada A, Onodera H Tags: Comput Methods Biomech Biomed Engin Source Type: research

Parametric study of anterior percutaneous endoscopic cervical discectomy (APECD).
In this study, the effects of various channel diameters and approach angles on cervical vertebrae on postoperative outcomes in APECD surgery were explored. A finite element model of intact cervical C3-C7 was constructed and then modified to obtain six surgical models. Range of motion (ROM) and intradiscal pressure (IDP) were calculated under different conditions of flexion (Fle), extension (Ext), lateral bending, and axial rotation. During Fle and bending to the left (LB), the ROM was closer to the intact model when the angle of approach was 90°. During bending to the left (LB) and rotation to the left (LR), the ROM ch...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 1, 2020 Category: Biomedical Engineering Authors: Sun MS, Yuchi CX, Cai XY, Du CF, Mo ZJ Tags: Comput Methods Biomech Biomed Engin Source Type: research

Image-based morphometric studies of human coronary artery bifurcations with/without coronary artery disease.
Abstract It is of great clinical significance to study the relationship between coronary bifurcation's morphometrical feature change and coronary artery disease (CAD) lesion. The purpose of this study is to determine the morphological changes in patients with CAD lesion when compared with non-CAD subjects and to find indicators that may be used for cardiovascular disease diagnosis. Computed tomography angiography images from Southern Chinese populations were used to reconstruct three-dimensional coronary arterial trees. Murray's law was introduced to assess the level of deviation of the realistic vascular networks...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 30, 2020 Category: Biomedical Engineering Authors: Chen X, Dai J, Lin J, Wu Y, Ouyang J, Huang M, Zhuang J, Fang Y, Wu J Tags: Comput Methods Biomech Biomed Engin Source Type: research

Investigation of two-body wear behavior of zirconia-reinforced lithium silicate glass-ceramic for biomedical applications; in vitro chewing simulation.
edil; Abstract The aim of this work was to the investigate two-body wear behavior of zirconia-reinforced lithium silicate glass-ceramic and composite resins through in vitro chewing simulation. Two types of glass-ceramics (IPS e.max CAD; lithium disilicate, Vita Suprinity; zirconia-reinforced lithium silicate) and two types of composite resins (Filtek Supreme; nano-filled, Ivoclar Vivadent Heliomolar; micro-filled) were used. All specimens were exposed to two-body wear tests using a dual-axis computer-controlled chewing simulation. Each chewing simulation test procedure, Al2O3 ball with a diameter of 6 mm, ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 30, 2020 Category: Biomedical Engineering Authors: Yilmaz EÇ Tags: Comput Methods Biomech Biomed Engin Source Type: research

Numerical analysis of the effects of ossicular chain malformations on bone conduction stimulation.
Abstract To assess the effects of ossicular chain malformations on the performance of bone conduction hearing aids, a human ear finite-element model that includes an ear canal, a middle ear, and a spiral cochlea incorporating the third windows was established. This finite element model was built based on micro-computed tomography scanning and reverse modelling techniques, and the reliability of the finite element model was verified by comparison with reported experimental data. Based on this model, two main types of ossicular chain malformations, i.e., the incudostapedial disconnection and the ossicles fixation, w...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 30, 2020 Category: Biomedical Engineering Authors: Zhao Y, Liu W, Liu H, Yang J, Zhou L, Huang X Tags: Comput Methods Biomech Biomed Engin Source Type: research

Mitigation of ocular artifacts for EEG signal using improved earth worm optimization-based neural network and lifting wavelet transform.
Abstract An Electroencephalogram (EEG) is often tarnished by various categories of artifacts. Numerous efforts have been taken to improve its quality by eliminating the artifacts. The EEG involves the biological artifacts (ocular artifacts, ECG and EMG artifacts), and technical artifacts (noise from the electric power source, amplitude artifacts, etc.). From these physiological artifacts, ocular activities are one of the most well-known over other noise sources. Reducing the risks of this event and avoid it is practically very difficult, even impossible, as the ocular activities are involuntary tasks. To trim down...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 27, 2020 Category: Biomedical Engineering Authors: Prasad DS, Chanamallu SR, Prasad KS Tags: Comput Methods Biomech Biomed Engin Source Type: research

Biomechanical evaluation of a novel mandibular distraction osteogenesis protocol: an in-vitro validation and the practical use of the method.
ml; Abstract The aim of this study was to optimize and experimentally validate the certain parameters affecting the operation success of Mandibular Distraction Osteogenesis (MDO). According to FEA results, the displacement of the samples showed 28.5% reduction as only the osteotomy line was separately optimized, and 64.2% less displacement was determined when the osteotomy line and the screw configuration were optimized together. In consistent with the FEA results, the samples showed 62% and 84.5% fewer displacement values, respectively. As a result, the MDO protocol suggested, which is validated by both numerical...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 26, 2020 Category: Biomedical Engineering Authors: Şensoy AT, Kaymaz I, Ertaş Ü Tags: Comput Methods Biomech Biomed Engin Source Type: research

Biomechanical analysis of lumbar spine with interbody fusion surgery and U-shaped lumbar interspinous spacers.
Abstract Previous research indicates whole-body vibration may lead to low back pain. The aim of this study is assessing the dynamic characteristics of a lumbar spine with Coflex and Coflex-F (commercial implants used as lumbar interspinous spacers) and effect of lumbar interbody fusion surgery. A transient dynamic analysis is performed on three numerical lumbar spine models under the loading condition of a vertical sinusoidal force of ±40 N with a compressive follower preload of 400 N. Also, Coflex-F model with and without interbody fusion surgery is analyzed under the same loading condition. ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 26, 2020 Category: Biomedical Engineering Authors: Yin JY, Guo LX Tags: Comput Methods Biomech Biomed Engin Source Type: research

A 3D registration methodology to evaluate the goodness of fit at the individual-respiratory mask interface.
This study aimed to analyse respiratory mask goodness of fit in a cohort of face shapes. A number of parameters were identified and analysed with a novel registration protocol. In the majority of cases, mask indentation exceeded the thickness of the interface material and significant gapping was observed. The size range was most appropriate for males, with only one size suitable for females. PMID: 33241703 [PubMed - as supplied by publisher] (Source: Computer Methods in Biomechanics and Biomedical Engineering)
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 26, 2020 Category: Biomedical Engineering Authors: Verberne JWR, Worsley PR, Bader DL Tags: Comput Methods Biomech Biomed Engin Source Type: research

Finite element analysis of human skull bone adaptation to mechanical loading.
The objective of this research was to develop an integrated bone remodeling and stress binning algorithms into a finite element environment to elucidate the evolution of the bone properties as a function of loading. The bone remodeling algorithm was used to calculate the change in the density and elastic modulus based on the strain energy stimulus. The stress-binning procedure seeks to assign the properties to each element based on the levels of stress from the previous cycle, eliminating pseudo-lazy-zoning and stress dilation effects. The developed algorithms were used to analyze the response skull to loading associated w...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 26, 2020 Category: Biomedical Engineering Authors: Gonzalez J, Nacy S, Youssef G Tags: Comput Methods Biomech Biomed Engin Source Type: research

Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation.
Abstract Atherosclerosis is a progressive disease that can significantly reduce blood supply to vital organs, being one of the main causes of death worldwide. In this work, a numerical and experimental study in 3 D printed stenotic coronary arteries is presented, considering both steady and pulsatile blood flow conditions, is presented. The results revealed that a degree of stenosis superior to 50% creates disturbed flows downstream of the contraction, with an accented increase in the wall shear stress measurements at the stenosis throat. Finally, the multiphase mixture was investigated and compared with a ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 23, 2020 Category: Biomedical Engineering Authors: Carvalho V, Rodrigues N, Ribeiro R, Costa PF, Teixeira JCF, Lima RA, Teixeira SFCF Tags: Comput Methods Biomech Biomed Engin Source Type: research

Mechanical effects of distributed fibre orientation in the periodontal ligament of an idealised geometry.
In this study, we computationally assess the effects of the distributed fibre orientation in the periodontal ligament (PDL) on mechanical responses of the tooth-PDL complex. An idealised axial-symmetric geometry of a tooth-PDL complex was constructed. The fibre orientation in the PDL was modelled as a trigonometric function based on anatomical knowledge, and the PDL was modelled as a transversely isotropic hyperelastic material dependent on fibre orientations. Parametric studies of the fibre orientation on the mechanical responses of the tooth-PDL complex were conducted. Obtained results showed that the anatomically consis...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 23, 2020 Category: Biomedical Engineering Authors: Otani T, Koga T, Nozaki K, Kobayashi Y, Tanaka M Tags: Comput Methods Biomech Biomed Engin Source Type: research

Biomechanical assessment of screw safety between far cortical locking and locked plating constructs.
This study utilized simulation with diaphyseal bridge plating biomechanical models to investigate whether far cortical locking causes larger screw fracture risk than LP during rehabilitation. The fracture risk of the screws in the far cortical locking constructs increases in the non-osteoporotic and osteoporotic diaphysis compared with the screws in the LP constructs. PMID: 33215954 [PubMed - as supplied by publisher] (Source: Computer Methods in Biomechanics and Biomedical Engineering)
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 20, 2020 Category: Biomedical Engineering Authors: Deng Y, Ouyang H, Xie P, Wang Y, Yang Y, Tan W, Zhao D, Zhong S, Huang W Tags: Comput Methods Biomech Biomed Engin Source Type: research

The risk factors for early conversion to total knee arthroplasty after high tibial osteotomy.
In this study, thirty-five (14.6%) patients were early conversion to TKA within a 5-year follow-up. These results indicated that age, body mass index (BMI), preoperative Kellgren-Lawrence (K-L) grade and preoperative visual analogue scale (VAS) score were potential risk factors for HTO survivorship. The cut-off values of those factors were 60 years, 25.35 kg/m2, 2 and 5, respectively. The combination of age, BMI, preoperative K-L grade and preoperative VAS score has the highest predictive value for HTO survivorship (AUC = 0.896, P 60 years, BMI>25.35 kg/m2, preoperative K-L grade>2 ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 19, 2020 Category: Biomedical Engineering Authors: Li HB, Nie S, Lan M, Tang ZM, Liao XG Tags: Comput Methods Biomech Biomed Engin Source Type: research

A model-based approach to predict neuromuscular control patterns that minimize ACL forces during jump landing.
Abstract Jump landing is a common situation leading to knee injuries involving the anterior cruciate ligament (ACL) in sports. Although neuromuscular control is considered as a key injury risk factor, there is a lack of knowledge regarding optimum control strategies that reduce ACL forces during jump landing. In the present study, a musculoskeletal model-based computational approach is presented that allows identifying neuromuscular control patterns that minimize ACL forces during jump landing. The approach is demonstrated for a jump landing maneuver in downhill skiing, which is one out of three main injury mechan...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 13, 2020 Category: Biomedical Engineering Authors: Heinrich D, van den Bogert AJ, Csapo R, Nachbauer W Tags: Comput Methods Biomech Biomed Engin Source Type: research