Discovering effect of intuitionistic fuzzy transformation in multi-layer perceptron for heart disease prediction: a study
Comput Methods Biomech Biomed Engin. 2023 Nov 27:1-15. doi: 10.1080/10255842.2023.2284095. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is the one of the most fatal diseases in the world we have seen in last two decades. For heart disease detection, imprecision in clinical parameters may occur due to error in taking readings or in measuring devices or environmental conditions etc. Hence, introducing fuzzy set theory in feature engineering may give better results as it deals with uncertainty. But in fuzzy set theory, only one uncertainty is considered, which is membership degree or degree of belongingness. Int...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 28, 2023 Category: Biomedical Engineering Authors: Chandan Pan Tamalika Chaira Ajoy Kumar Ray Source Type: research

Identifying the cancer-associated fibroblast signature to predict the prognosis and immunotherapy response in patients with lung squamous cell carcinoma
This study aimed to establish a new algorithm based on CAF scores to predict the prognosis and immunotherapy response in patients with lung squamous cell carcinoma (LUSC). The RNA-seq data of LUSC patients were obtained from two databases and merged after removing inter-batch differences. The CAF-related data for each sample were obtained through three different algorithms. Consistency cluster analysis was performed to obtain different CAF clusters, which were analyzed to identify differentially expressed genes. These were subjected to uniform cluster analysis to obtain different gene clusters. The Boruta algorithm was use...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 28, 2023 Category: Biomedical Engineering Authors: Yinhui Zhu Yingqun Zhu Sirui Chen Qian Cai Source Type: research

Mechanics of ascending aortic aneurysms based on a modulus of elasticity dependent on aneurysm diameter and pressure
Comput Methods Biomech Biomed Engin. 2023 Nov 27:1-16. doi: 10.1080/10255842.2023.2285722. Online ahead of print.ABSTRACTThe mechanical stresses and strains are examined, in ascending thoracic aortic aneurysm (aTAA) models, in a patient-specific aTAA as well as in healthy thoracic aortic models, via Finite Element Analysis. The aneurysms are assumed spherical, 1.5 mm thick, with diameters between 47 mm and 80 mm, eccentrically positioned. The geometry and wall thickness distribution of the aorta along its length are based on open literature data for an average patient age of 66.25 years, accounting for the Body Surface Are...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 27, 2023 Category: Biomedical Engineering Authors: Christos Manopoulos Konstantinos Seferlis Anastasios Raptis Ilias Kouerinis Dimitrios Mathioulakis Source Type: research

Hemodynamic analysis of unilateral and bilateral renal artery stenosis based on fluid-structure interaction
Comput Methods Biomech Biomed Engin. 2023 Nov 27:1-12. doi: 10.1080/10255842.2023.2282949. Online ahead of print.ABSTRACTRenal artery stenosis (RAS) hypertension is a common type of secondary hypertension. This paper aimed to explore how unilateral renal artery stenosis (Uni-RAS) and bilateral renal artery stenosis (Bi-RAS) caused renovascular hypertension with the fluid-structure interaction (FSI) method. Based on a real RAS model, 20 ideal models with different stenosis degrees were established by modifying the stenosis segment. The hemodynamic parameters at different degrees of stenosis, mass flow rate (MFR), pressure d...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 27, 2023 Category: Biomedical Engineering Authors: Bingxin Liu Jiawei Zhao Xuehui Chen Kun Fang Weidong Yang Xuelan Zhang Chang Shu Source Type: research

An ensemble-based serial cascaded attention network and improved variational auto encoder for breast cancer prognosis prediction using data
Comput Methods Biomech Biomed Engin. 2023 Nov 24:1-18. doi: 10.1080/10255842.2023.2280883. Online ahead of print.ABSTRACTBreast cancer is one of the most common types of cancer in women and it produces a huge amount of death rate in the world. Early recognition is lessening its impact. The early recognition of breast cancer could convince patients to receive surgical therapy, which will significantly improve the chance of restoration. This information is used by the machine learning technique to find links between them and appraise our forecasts of fresh occurrences. Later recognition of breast cancer can lead to death. An...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 25, 2023 Category: Biomedical Engineering Authors: P Vanmathi Deepa Jose Source Type: research

Hypopharyngeal geometry impact on air-induced loads on the supraglottis
This study investigates the influence of hypopharyngeal and laryngeal geometry on upper respiratory tract airflow and air-induced forces. A computational fluid dynamics model is developed to study airflow through larynx. Four real, adult upper respiratory tracts with variable configurations are considered. Two steady, uniform inspiratory flow rates of 60 L/min and 180 L/min are considered. The analysis shows that geometries with a space lateral to the epiglottis (EpiS) and piriform fossae (PF) directs the hypopharyngeal and supraglottic pressure field to remain positive and increase with the flow rate. In geometries with E...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 25, 2023 Category: Biomedical Engineering Authors: L Reid M Hayatdavoodi Source Type: research

A novel intramedullary nail design of intertrochanteric fracture fixation improved by proximal femoral nail antirotation
In this study, we propose a novel intramedullary nail design to enhance the intramedullary nail integrity by introducing a bolt screw to form a stable triangular structure composed of the nail, the lag screw, and the bolt screw (PFTN, Proximal femoral triangle nail). Systematic finite element numerical simulations were carried out to compare the biomechanical performances of PFTN and PFNA under both static and dynamic loads during the postures of ascending and descending stairs. The simulation results highlight the advantages of the proposed PFTN design with lower stresses, less stress concentration, and higher structure s...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 25, 2023 Category: Biomedical Engineering Authors: Ze She Fan Yang Siyuan Zhang Liang Yang Xin Wang Source Type: research

An ensemble-based serial cascaded attention network and improved variational auto encoder for breast cancer prognosis prediction using data
Comput Methods Biomech Biomed Engin. 2023 Nov 24:1-18. doi: 10.1080/10255842.2023.2280883. Online ahead of print.ABSTRACTBreast cancer is one of the most common types of cancer in women and it produces a huge amount of death rate in the world. Early recognition is lessening its impact. The early recognition of breast cancer could convince patients to receive surgical therapy, which will significantly improve the chance of restoration. This information is used by the machine learning technique to find links between them and appraise our forecasts of fresh occurrences. Later recognition of breast cancer can lead to death. An...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 25, 2023 Category: Biomedical Engineering Authors: P Vanmathi Deepa Jose Source Type: research

Hypopharyngeal geometry impact on air-induced loads on the supraglottis
This study investigates the influence of hypopharyngeal and laryngeal geometry on upper respiratory tract airflow and air-induced forces. A computational fluid dynamics model is developed to study airflow through larynx. Four real, adult upper respiratory tracts with variable configurations are considered. Two steady, uniform inspiratory flow rates of 60 L/min and 180 L/min are considered. The analysis shows that geometries with a space lateral to the epiglottis (EpiS) and piriform fossae (PF) directs the hypopharyngeal and supraglottic pressure field to remain positive and increase with the flow rate. In geometries with E...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 25, 2023 Category: Biomedical Engineering Authors: L Reid M Hayatdavoodi Source Type: research

A novel intramedullary nail design of intertrochanteric fracture fixation improved by proximal femoral nail antirotation
In this study, we propose a novel intramedullary nail design to enhance the intramedullary nail integrity by introducing a bolt screw to form a stable triangular structure composed of the nail, the lag screw, and the bolt screw (PFTN, Proximal femoral triangle nail). Systematic finite element numerical simulations were carried out to compare the biomechanical performances of PFTN and PFNA under both static and dynamic loads during the postures of ascending and descending stairs. The simulation results highlight the advantages of the proposed PFTN design with lower stresses, less stress concentration, and higher structure s...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 25, 2023 Category: Biomedical Engineering Authors: Ze She Fan Yang Siyuan Zhang Liang Yang Xin Wang Source Type: research

An ensemble-based serial cascaded attention network and improved variational auto encoder for breast cancer prognosis prediction using data
Comput Methods Biomech Biomed Engin. 2023 Nov 24:1-18. doi: 10.1080/10255842.2023.2280883. Online ahead of print.ABSTRACTBreast cancer is one of the most common types of cancer in women and it produces a huge amount of death rate in the world. Early recognition is lessening its impact. The early recognition of breast cancer could convince patients to receive surgical therapy, which will significantly improve the chance of restoration. This information is used by the machine learning technique to find links between them and appraise our forecasts of fresh occurrences. Later recognition of breast cancer can lead to death. An...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 25, 2023 Category: Biomedical Engineering Authors: P Vanmathi Deepa Jose Source Type: research

Evaluation of AIS3+ car occupant injuries using deterministic and probabilistic methods in frontal crashes
Comput Methods Biomech Biomed Engin. 2023 Nov 23:1-17. doi: 10.1080/10255842.2023.2283692. Online ahead of print.ABSTRACTComputational modelling was used to assess the capability of a deterministic and a probabilistic method to predict the incidence of AIS3+ injuries in passenger car occupants by comparing the predictions of the methods to the actual injuries observed in real-world crashes. The likelihood of sustaining an injury was first calculated using a computer model for a selected set of injury criteria in different impact conditions based on real-world crashes; AIS3+ injuries were then predicted using each method se...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 23, 2023 Category: Biomedical Engineering Authors: M Valdano J R Jim énez-Octavio B Pipkorn A Otero Peinador L F S ánchez-Merchante F J L ópez-Valdés Source Type: research

Evaluation of AIS3+ car occupant injuries using deterministic and probabilistic methods in frontal crashes
Comput Methods Biomech Biomed Engin. 2023 Nov 23:1-17. doi: 10.1080/10255842.2023.2283692. Online ahead of print.ABSTRACTComputational modelling was used to assess the capability of a deterministic and a probabilistic method to predict the incidence of AIS3+ injuries in passenger car occupants by comparing the predictions of the methods to the actual injuries observed in real-world crashes. The likelihood of sustaining an injury was first calculated using a computer model for a selected set of injury criteria in different impact conditions based on real-world crashes; AIS3+ injuries were then predicted using each method se...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 23, 2023 Category: Biomedical Engineering Authors: M Valdano J R Jim énez-Octavio B Pipkorn A Otero Peinador L F S ánchez-Merchante F J L ópez-Valdés Source Type: research

Multivariable identification based MPC for closed-loop glucose regulation subject to individual variability
In this study, a multivariable identification based model predictive control (mi-MPC) is developed to overcome the above challenges. Firstly, an integrated glucose-insulin model is established to describe insulin absorption, glucose-insulin interaction under meal disturbance, and glucose transport. On this basis, an observable glucose-insulin dynamic model is formed, in which the individual parameters and disturbances can be identified by designing a particle filtering estimator. Next, embedded with the identified glucose-insulin dynamic model, a mi-MPC method is proposed. In this controller, plasma glucose concentration (...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 20, 2023 Category: Biomedical Engineering Authors: Weijie Wang Shaoping Wang Yuwei Zhang Yixuan Geng Deng'ao Li Shiwei Liu Source Type: research

Research on MI EEG signal classification algorithm using multi-model fusion strategy coupling
Comput Methods Biomech Biomed Engin. 2023 Nov 20:1-10. doi: 10.1080/10255842.2023.2284091. Online ahead of print.ABSTRACTTo enhance the accuracy of motor imagery(MI)EEG signal recognition, two methods, namely power spectral density and wavelet packet decomposition combined with a common spatial pattern, were employed to explore the feature information in depth in MI EEG signals. The extracted MI EEG signal features were subjected to series feature fusion, and the F-test method was used to select features with higher information content. Here regarding the accuracy of MI EEG signal classification, we further proposed the Pl...
Source: Computer Methods in Biomechanics and Biomedical Engineering - November 20, 2023 Category: Biomedical Engineering Authors: Wu Quanyu Ding Sheng Tao Weige Pan Lingjiao Liu Xiaojie Source Type: research