Computer Methods in Biomechanics and Biomedical Engineering This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Biomechanical effects of different loads and constraints on finite element modeling of the humerus
Comput Methods Biomech Biomed Engin. 2023 Dec 27:1-13. doi: 10.1080/10255842.2023.2298371. Online ahead of print.ABSTRACTCurrently, there is no established finite element (FE) method to apply physiologically realistic loads and constraints to the humerus. This FE study showed that 2 'simple' methods involving direct head loads, no head constraints, and rigid elbow or mid-length constraints created excessive stresses and bending. However, 2 'intermediate' methods involving direct head loads, but flexible head and elbow constraints, produced lower stresses and bending. Also, 2 'complex' methods involving muscles to generate ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 28, 2023 Category: Biomedical Engineering Authors: Sabrina Islam Kunal Gide Emil H Schemitsch Habiba Bougherara Radovan Zdero Z Shaghayegh Bagheri Source Type: research

Treatment prediction with machine learning in prostate cancer patients
In this study, it is aimed to make predictions with machine learning in order to determine the optimal treatment option for prostate cancer patients. The study included 88 male patients diagnosed with prostate cancer. Independent variables were determined as Gleason scores, biopsy, PSA, SUVmax, and age. Prostate cancer treatments, which are dependent variables, were determined as hormone therapy(n = 30), radiotherapy(n = 28) and radiotherapy + hormone therapy(n = 30). Machine learning was carried out in the Python with SVM, RF, DT, ETC and XGBoost. Metrics such as accuracy, ROC curve, and AUC were used to evaluate the perf...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Emre Alata ş Handan Tany ıldızı Kökkülünk Hilal Tany ıldızı Goksel Alc ın Source Type: research

A scale conjugate neural network approach for the fractional schistosomiasis disease system
This study presents the numerical solutions of the fractional schistosomiasis disease model (SDM) using the supervised neural networks (SNNs) and the computational scaled conjugate gradient (SCG), i.e. SNNs-SCG. The fractional derivatives are used for the precise outcomes of the fractional SDM. The preliminary fractional SDM is categorized as: uninfected, infected with schistosomiasis, recovered through infection, expose and susceptible to this virus. The accurateness of the SNNs-SCG is performed to solve three different scenarios based on the fractional SDM with synthetic data obtained with fractional Adams scheme (FAS). ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Zulqurnain Sabir Shahid Ahmad Bhat Muhammad Asif Zahoor Raja Dumitru Baleanu Fazli Amin Hafiz Abdul Wahab Source Type: research

A fractional modeling approach for the transmission dynamics of measles with double-dose vaccination
This study examines a SEIVR compartmental model in the caputo sense using a double dose of vaccine to simulate the measles outbreak. The reproduction number R0 and model properties are both thoroughly examined. Both the local and global stabilities of the proposed model are determined for R0 less and greater than 1. To achieve the model's global stability, the Lyapunov function is used while the existence and uniqueness of the proposed model are demonstrated In addition to the calculated and fitted biological parameters, the forward sensitivity indices for R0 are also obtained. Simulations of the proposed fractional order ...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Muhammad Farhan Zahir Shah Rashid Jan Saeed Islam Mansoor H Alshehri Zhi Ling Source Type: research

Numerical simulation of the blood flow through a pre-stenotic aneurysm in coronary artery: effects of varying heart rate
Comput Methods Biomech Biomed Engin. 2023 Dec 26:1-19. doi: 10.1080/10255842.2023.2297659. Online ahead of print.ABSTRACTThe left anterior descending artery (LAD) is a significant coronary artery and a facilitator of oxygenated blood to the heart muscles. Thus, any occurrence of an aneurysm in LAD requires immediate medical attention. It is often inclined toward fatality if coupled with a blockage due to stenosis. Given the high relevance of understanding such models, invasive techniques under all parametric circumstances are hard to achieve. So, a theoretical approach with a cost-effective intervention of mathematical mod...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 26, 2023 Category: Biomedical Engineering Authors: Mahesh C Udupa Sunanda Saha Sekarapandian Natarajan Source Type: research

Modeling and simulation credibility assessments of whole-body finite element computational models for use in NASA extravehicular activity applications
Comput Methods Biomech Biomed Engin. 2023 Dec 21:1-14. doi: 10.1080/10255842.2023.2293653. Online ahead of print.ABSTRACTComputational finite element (FE) models are used in suited astronaut injury risk assessments; however, these models' verification, validation, and credibility (VV&C) procedures for simulating injuries in altered gravity environments are limited. Our study conducts VV&C assessments of THUMS and Elemance whole-body FE models for predicting suited astronaut injury biomechanics using eight credibility factors, as per NASA-STD-7009A. Credibility factor ordinal scores are assigned by reviewing existin...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 22, 2023 Category: Biomedical Engineering Authors: Richard A Perkins Christopher A Gallo Athena E Ivanoff Keegan M Yates Courtney M Schkurko Jeffrey T Somers Nathaniel J Newby Jerry G Myers Raj K Prabhu Source Type: research

A physiologically enhanced muscle spindle model: using a Hill-type model for extrafusal fibers as template for intrafusal fibers
Comput Methods Biomech Biomed Engin. 2023 Dec 21:1-20. doi: 10.1080/10255842.2023.2293652. Online ahead of print.ABSTRACTThe muscle spindle is an essential proprioceptor, significantly involved in sensing limb position and movement. Although biological spindle models exist for years, the gold-standard for motor control in biomechanics are still sensors built of homogenized spindle output models due to their simpler combination with neuro-musculoskeletal models. Aiming to improve biomechanical simulations, this work establishes a more physiological model of the muscle spindle, aligned to the advantage of easy integration in...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 21, 2023 Category: Biomedical Engineering Authors: Pablo F S Chacon Maria Hammer Isabell Wochner Johannes R Walter Syn Schmitt Source Type: research

Nested genetic algorithm-based classifier selection and placement in multi-level ensemble framework for effective disease diagnosis
Comput Methods Biomech Biomed Engin. 2023 Dec 21:1-24. doi: 10.1080/10255842.2023.2294264. Online ahead of print.ABSTRACTEffective disease diagnosis is a critical unmet need on a global scale. The intricacies of the numerous disease mechanisms and underlying symptoms make developing a model for early diagnosis and effective treatment extremely difficult. Machine learning (ML) can help to solve some of these issues. Recently, various ensemble-based ML models have benefited clinicians in early diagnosis. However, one of the most difficult challenges in multi-level ensemble approaches is the classifier selection and their pla...
Source: Computer Methods in Biomechanics and Biomedical Engineering - December 21, 2023 Category: Biomedical Engineering Authors: Srinivas Arukonda Ramalingaswamy Cheruku Source Type: research