Finite element modeling of the free boundary effect on gyroid additively manufactured samples
Comput Methods Biomech Biomed Engin. 2024 Mar 12:1-12. doi: 10.1080/10255842.2024.2326929. Online ahead of print.ABSTRACTThere is a significant need for models that can capture the mechanical behavior of complex porous lattice architectures produced by 3D printing. The free boundary effect is an experimentally observed behavior of lattice architectures including the gyroid triply periodic minimal surface where the number of unit cell repeats has been shown to influence the mechanical performance of the lattice. The purpose of this study is to use finite element modeling to investigate how architecture porosity, unit cell s...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 12, 2024 Category: Biomedical Engineering Authors: Elizabeth Mathey Amanda Heimbrook R D Carpenter Cambre N Kelly Ken Gall Source Type: research

Design and performance analysis of a new inferior vena cava filter
This study proposes a novel inferior vena cava filter (IVCF) design, "Lotus," aiming to enhance release stability and endothelialization. A catheter-filter-vessel model was established for IVCF property analysis, validated by comparing numerical simulations and in vitro tests. Lotus's mechanical properties were analyzed, and optimization suggestions are provided. Compared to existing clinical filters, Lotus demonstrates improved release stability and thrombus capture ability. This work suggests Lotus as a potential technical reference for improved IVCF treatment.PMID:38461446 | DOI:10.1080/10255842.2024.2326084 (Source: Co...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 10, 2024 Category: Biomedical Engineering Authors: Xianying Wang Huajie Wang Hongliang Qian Hongdong Su Deda Lou Lijian Tian Deshen Chen Huafang Ding Feng Fan Source Type: research

CFD simulation of cannabidiol delivery through microneedle patches
This study investigates the efficiency and influence of microneedle parameters, specifically Needle Point Angle (a) and Needle Height (h), on the diffusion of Cannabidiol (CBD) across varying skin depths. Utilizing the Latin Hypercube Sampling method, twelve distinct cases were analyzed. Observations reveal a consistent high concentration of CBD delivered via the microneedle patch, with a notable decrease in concentration as the depth increases, displaying a non-linear trend. Multivariate polynomial regression offers a quantitative relationship between the variables, with the third-order bivariate fitting providing the mos...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 10, 2024 Category: Biomedical Engineering Authors: Liqun Shi Jianfeng Xu Lihua Zhang Weiping Zuo Binbin Ni Mingqiang Lai Maoqi Fu Source Type: research

Poroelastic modelling of brain tissue swelling and decompressive craniectomy treatment in ischaemic stroke
In this study, a poroelastic model is used to investigate the effect of brain ischaemic infarct size and location on the severity of brain tissue swelling. Furthermore, the model will also be used to evaluate the effectiveness of DC surgery as a treatment for brain tissue swelling after ischaemia. The poroelastic model consists of two equations: one describing the elasticity of the brain tissue and the other describing the changes in the interstitial tissue pressure. The model is applied on an idealized brain geometry, and it is found that infarcts with radius larger than approximately 14 mm and located near the lateral ve...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 10, 2024 Category: Biomedical Engineering Authors: Aina Najwa Nadzri Nik Abdullah Nik Mohamed Stephen J Payne Mohd Jamil Mohamed Mokhtarudin Source Type: research

Design and performance analysis of a new inferior vena cava filter
This study proposes a novel inferior vena cava filter (IVCF) design, "Lotus," aiming to enhance release stability and endothelialization. A catheter-filter-vessel model was established for IVCF property analysis, validated by comparing numerical simulations and in vitro tests. Lotus's mechanical properties were analyzed, and optimization suggestions are provided. Compared to existing clinical filters, Lotus demonstrates improved release stability and thrombus capture ability. This work suggests Lotus as a potential technical reference for improved IVCF treatment.PMID:38461446 | DOI:10.1080/10255842.2024.2326084 (Source: Co...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 10, 2024 Category: Biomedical Engineering Authors: Xianying Wang Huajie Wang Hongliang Qian Hongdong Su Deda Lou Lijian Tian Deshen Chen Huafang Ding Feng Fan Source Type: research

CFD simulation of cannabidiol delivery through microneedle patches
This study investigates the efficiency and influence of microneedle parameters, specifically Needle Point Angle (a) and Needle Height (h), on the diffusion of Cannabidiol (CBD) across varying skin depths. Utilizing the Latin Hypercube Sampling method, twelve distinct cases were analyzed. Observations reveal a consistent high concentration of CBD delivered via the microneedle patch, with a notable decrease in concentration as the depth increases, displaying a non-linear trend. Multivariate polynomial regression offers a quantitative relationship between the variables, with the third-order bivariate fitting providing the mos...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 10, 2024 Category: Biomedical Engineering Authors: Liqun Shi Jianfeng Xu Lihua Zhang Weiping Zuo Binbin Ni Mingqiang Lai Maoqi Fu Source Type: research

Poroelastic modelling of brain tissue swelling and decompressive craniectomy treatment in ischaemic stroke
In this study, a poroelastic model is used to investigate the effect of brain ischaemic infarct size and location on the severity of brain tissue swelling. Furthermore, the model will also be used to evaluate the effectiveness of DC surgery as a treatment for brain tissue swelling after ischaemia. The poroelastic model consists of two equations: one describing the elasticity of the brain tissue and the other describing the changes in the interstitial tissue pressure. The model is applied on an idealized brain geometry, and it is found that infarcts with radius larger than approximately 14 mm and located near the lateral ve...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 10, 2024 Category: Biomedical Engineering Authors: Aina Najwa Nadzri Nik Abdullah Nik Mohamed Stephen J Payne Mohd Jamil Mohamed Mokhtarudin Source Type: research

Seizure prediction based on improved vision transformer model for EEG channel optimization
Comput Methods Biomech Biomed Engin. 2024 Mar 6:1-12. doi: 10.1080/10255842.2024.2326097. Online ahead of print.ABSTRACTEpileptic seizures are unpredictable events caused by abnormal discharges of a patient's brain cells. Extensive research has been conducted to develop seizure prediction algorithms based on long-term continuous electroencephalogram (EEG) signals. This paper describes a patient-specific seizure prediction method that can serve as a basis for the design of lightweight, wearable and effective seizure-prediction devices. We aim to achieve two objectives using this method. The first aim is to extract robust fe...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 7, 2024 Category: Biomedical Engineering Authors: Nan Qi Yan Piao Hao Zhang Qi Wang Yue Wang Source Type: research

Study on the effect of human sympathetic nerve cold stimulation to relieve driving fatigue based on order recurrence plot
This study proposes a method to relieve driving fatigue by properly reducing the temperature to stimulate the human sympathetic nerve. The method uses the intelligent cooling and blowing device on the car seat cushion to achieve cold stimulation of the sympathetic nerve of the driver by reducing the temperature of the driver's hip, back and neck, so as to increase the excitement of the sympathetic nerve, keep the driver alert and achieve the purpose of fighting driving fatigue. In view of the fact that the traditional fatigue detection method is easily affected by environmental factors and individual differences, this stud...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 7, 2024 Category: Biomedical Engineering Authors: Fuwang Wang Daping Chen Source Type: research

Seizure prediction based on improved vision transformer model for EEG channel optimization
Comput Methods Biomech Biomed Engin. 2024 Mar 6:1-12. doi: 10.1080/10255842.2024.2326097. Online ahead of print.ABSTRACTEpileptic seizures are unpredictable events caused by abnormal discharges of a patient's brain cells. Extensive research has been conducted to develop seizure prediction algorithms based on long-term continuous electroencephalogram (EEG) signals. This paper describes a patient-specific seizure prediction method that can serve as a basis for the design of lightweight, wearable and effective seizure-prediction devices. We aim to achieve two objectives using this method. The first aim is to extract robust fe...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 7, 2024 Category: Biomedical Engineering Authors: Nan Qi Yan Piao Hao Zhang Qi Wang Yue Wang Source Type: research

Study on the effect of human sympathetic nerve cold stimulation to relieve driving fatigue based on order recurrence plot
This study proposes a method to relieve driving fatigue by properly reducing the temperature to stimulate the human sympathetic nerve. The method uses the intelligent cooling and blowing device on the car seat cushion to achieve cold stimulation of the sympathetic nerve of the driver by reducing the temperature of the driver's hip, back and neck, so as to increase the excitement of the sympathetic nerve, keep the driver alert and achieve the purpose of fighting driving fatigue. In view of the fact that the traditional fatigue detection method is easily affected by environmental factors and individual differences, this stud...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 7, 2024 Category: Biomedical Engineering Authors: Fuwang Wang Daping Chen Source Type: research

Seizure prediction based on improved vision transformer model for EEG channel optimization
Comput Methods Biomech Biomed Engin. 2024 Mar 6:1-12. doi: 10.1080/10255842.2024.2326097. Online ahead of print.ABSTRACTEpileptic seizures are unpredictable events caused by abnormal discharges of a patient's brain cells. Extensive research has been conducted to develop seizure prediction algorithms based on long-term continuous electroencephalogram (EEG) signals. This paper describes a patient-specific seizure prediction method that can serve as a basis for the design of lightweight, wearable and effective seizure-prediction devices. We aim to achieve two objectives using this method. The first aim is to extract robust fe...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 7, 2024 Category: Biomedical Engineering Authors: Nan Qi Yan Piao Hao Zhang Qi Wang Yue Wang Source Type: research

Study on the effect of human sympathetic nerve cold stimulation to relieve driving fatigue based on order recurrence plot
This study proposes a method to relieve driving fatigue by properly reducing the temperature to stimulate the human sympathetic nerve. The method uses the intelligent cooling and blowing device on the car seat cushion to achieve cold stimulation of the sympathetic nerve of the driver by reducing the temperature of the driver's hip, back and neck, so as to increase the excitement of the sympathetic nerve, keep the driver alert and achieve the purpose of fighting driving fatigue. In view of the fact that the traditional fatigue detection method is easily affected by environmental factors and individual differences, this stud...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 7, 2024 Category: Biomedical Engineering Authors: Fuwang Wang Daping Chen Source Type: research

Seizure prediction based on improved vision transformer model for EEG channel optimization
Comput Methods Biomech Biomed Engin. 2024 Mar 6:1-12. doi: 10.1080/10255842.2024.2326097. Online ahead of print.ABSTRACTEpileptic seizures are unpredictable events caused by abnormal discharges of a patient's brain cells. Extensive research has been conducted to develop seizure prediction algorithms based on long-term continuous electroencephalogram (EEG) signals. This paper describes a patient-specific seizure prediction method that can serve as a basis for the design of lightweight, wearable and effective seizure-prediction devices. We aim to achieve two objectives using this method. The first aim is to extract robust fe...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 7, 2024 Category: Biomedical Engineering Authors: Nan Qi Yan Piao Hao Zhang Qi Wang Yue Wang Source Type: research

Study on the effect of human sympathetic nerve cold stimulation to relieve driving fatigue based on order recurrence plot
This study proposes a method to relieve driving fatigue by properly reducing the temperature to stimulate the human sympathetic nerve. The method uses the intelligent cooling and blowing device on the car seat cushion to achieve cold stimulation of the sympathetic nerve of the driver by reducing the temperature of the driver's hip, back and neck, so as to increase the excitement of the sympathetic nerve, keep the driver alert and achieve the purpose of fighting driving fatigue. In view of the fact that the traditional fatigue detection method is easily affected by environmental factors and individual differences, this stud...
Source: Computer Methods in Biomechanics and Biomedical Engineering - March 7, 2024 Category: Biomedical Engineering Authors: Fuwang Wang Daping Chen Source Type: research