Analysis of the main bioactive compounds from Ocimum basilicum for their antimicrobial and antioxidant activity
This study is aimed to assess the antimicrobial and antioxidant activity of basil leaf extract prepared using ethanol, methanol, and water. The ethanol and methanol extract have all the phytochemicals (alkaloids, flavonoids, phenolic compounds, tannins, saponins, quinones, carbohydrates, and proteins) except steroids and terpenoids. In addition to steroids and terpenoids, tannin was also absent in the aqueous extract. Total phenolic and flavonoid content was high in ethanol and followed by methanol and aqueous extract. Similarly, ethanol and methanol extract showed strong antimicrobial activity against VRE and MTCC strains...
Source: Biotechnology and Applied Biochemistry - August 28, 2023 Category: Biochemistry Authors: Arockia Doss Susai Backiam,
Senbagam Duraisamy,
Palaniyandi Karuppaiya,
Senthilkumar Balakrishnan,
Aswathy Sathyan,
Anbarasu Kumarasamy,
Amutha Raju Tags: ORIGINAL ARTICLE Source Type: research
Effects of Ocimum basilicum essential oil and ginger extract on serum biochemistry, oxidative stress and gill tissue damage of pearl gentian grouper during simulated live transport
This study explored the effects of the essential oil ofOcimum basilicum (EOOB) and ginger extract (GE) during the transportation of pearl gentian grouper from water quality, serum biochemistry, oxidative stress, meat flavor, and gill tissue morphology. Fish (450 ± 50 g) were allocated to the following 5 treatments: control group (fish transported in water only), 5 mg/LEOOB, 10 mg/LEOOB, 3 mg/LGE, and 6 mg/LGE and transported in insulation boxes (66 × 51 × 37.8 cm) for 72 h. Samples were taken at 0, 12, 36, 60, and 72 h immediately af ter transport. It was found that 10 mg/LEOOB and 6 mg/LGE could ...
Source: Veterinary Research Communications - August 12, 2023 Category: Veterinary Research Source Type: research
Encapsulation of purple basil leaf extract by electrospraying in double emulsion (W/O/W) filled alginate-carrageenan beads to improve the bioaccessibility of anthocyanins
Int J Biol Macromol. 2023 Aug 9:126207. doi: 10.1016/j.ijbiomac.2023.126207. Online ahead of print.ABSTRACTThe purple basil leaf extract (PBLE) was encapsulated in double emulsion (W1/O/W2)-loaded beads (emulgel) by electrospraying. The influence of κ-carrageenan (κ-CG) and cross-linking agents (Ca2+/K+) on the properties of alginate (SA) beads were assessed. In emulgel beads, κ-CG inclusion resulted in larger sizes and more distorted shapes, wrinkles on the surface, and lower gel strength. The encapsulation efficiency of anthocyanins (ACNs) in emulgel beads ranged from 70.73 to 87.89 %, whereas it ranged from 13.50 to ...
Source: International Journal of Biological Macromolecules - August 11, 2023 Category: Biochemistry Authors: Basak Ebru Ozcan Oznur Saroglu Canan Yagmur Karakas Ayse Karadag Source Type: research
Potential antihypertensive activity of novel peptides from green basil leaves
This study aimed to discover novel antihypertensive peptides fr... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - August 8, 2023 Category: Complementary Medicine Authors: Pattaneeya Prangthip, Watanalai Panbangred and Onrapak Reamtong Tags: Research Source Type: research
Molecules, Vol. 28, Pages 5286: Optimization of the Extraction Conditions of Bioactive Compounds from Ocimum basilicum Leaves Using Ultrasound-Assisted Extraction via a Sonotrode
Verardo
Sweet basil (Ocimum basilicum) leaves are rich in bioactive compounds that present therapeutic benefits for human health. Ultrasonic-assisted extraction (UAE) is frequently used to obtain phenolic compounds from plants/herbal sources. However, few works have developed multi-variable studies to find the optimal conditions to extract the maximum amount of compounds, especially when applied to UAE via a sonotrode. The purpose of this work was to perform a multi-variable study by employing a Box–Behnken design to collect the highest active compound content from Ocimum basilicum leaves. The efficac...
Source: Molecules - July 7, 2023 Category: Chemistry Authors: Aloisio Razola-D íaz Aznar-Ramos Longhi Andreatta Verardo Tags: Article Source Type: research
Assessment of anticancer, antimicrobial, antidiabetic, anti-obesity and antioxidant activity of Ocimum Basilicum seeds essential oil from Palestine
CONCLUSION: This study has provided initial data that supports the importance of O. basilcum essential oil in traditional medicine. The extracted oil not only exhibited significant anticancer, antimicrobial, and antioxidant properties but also antidiabetic and anti-obesity effects, which provided a foundation for future research.PMID:37403162 | DOI:10.1186/s12906-023-04058-w (Source: Cancer Control)
Source: Cancer Control - July 4, 2023 Category: Cancer & Oncology Authors: Ahmad M Eid Nidal Jaradat Naser Shraim Mohammed Hawash Linda Issa Mohammad Shakhsher Nour Nawahda Ali Hanbali Noor Barahmeh Basil Taha Ahmed Mousa Source Type: research
Assessment of anticancer, antimicrobial, antidiabetic, anti-obesity and antioxidant activity of Ocimum Basilicum seeds essential oil from Palestine
Many modern pharmaceutical researchers continue to focus on the discovery and evaluation of natural compounds for possible therapies for obesity, diabetes, infections, cancer, and oxidative stress. Extraction of (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 4, 2023 Category: Complementary Medicine Authors: Ahmad M Eid, Nidal Jaradat, Naser Shraim, Mohammed Hawash, Linda Issa, Mohammad Shakhsher, Nour Nawahda, Ali Hanbali, Noor Barahmeh, Basil Taha and Ahmed Mousa Tags: Research Source Type: research
Precursors and elicitor induced enhancement of cell biomass and phenolic compounds in cell suspensions of Indian basil- < em > Ocimum basilicum < /em > (CIM-Saumya)
Physiol Mol Biol Plants. 2023 May;29(5):679-693. doi: 10.1007/s12298-023-01316-6. Epub 2023 Jun 2.ABSTRACTCIM-Saumya is an improved, methyl chavicol rich variety of Ocimum basilicum (Family-Lamiaceae), developed by Council of Scientific and Industrial Research-Central Institute of Medicinal and Aromatic Plants. This plant possesses analgesic, anti-ulcerogenic, anti-inflammatory, anti-oxidant, cardiac stimulant, Central Nervous System depressant, hepatoprotective and immunomodulator activities due to the presence of various phytoconstituents. Among them rosmarinic acid, caffeic acid and ferulic acid are the three major phen...
Source: Mol Biol Cell - June 26, 2023 Category: Molecular Biology Authors: Mamta Kumari Archana Prasad Archana Mathur Ajay Kumar Mathur Laiq Ur-Rahman Manju Singh Raj Kishori Lal Source Type: research
Effects of Ocimum basilicum L. Extract on Hippocampal Oxidative Stress, Inflammation, and BDNF Expression in Amnesic Aged Rats
. (Source: Experimental Aging Research)
Source: Experimental Aging Research - May 8, 2023 Category: Geriatrics Authors: Farimah Beheshti Arefeh Vakilian Mohsen Navari Mostafa Zare Moghaddam Hossein Dinpanah S. Mohammad Ahmadi-Soleimani Source Type: research
In silico Study of Antiviral Activity of Polyphenol Compounds from < em > Ocimum basilicum < /em > by Molecular Docking, ADMET, and Drug-Likeness Analysis
CONCLUSION: Based on the data obtained, Apigenin-7-glucuronide and dihydrokaempferol-3-glucoside are compounds that have more potential to have an antiviral effect on the main protease enzyme than aesculetin. Based on pharmacokinetic parameters and drug-likeness, three compounds can be used as lead compounds for further research.PMID:37131997 | PMC:PMC10149097 | DOI:10.2147/AABC.S403175 (Source: Adv Data)
Source: Adv Data - May 3, 2023 Category: Epidemiology Authors: Dikdik Kurnia Salsabila Aqila Putri Sefren Geiner Tumilaar Achmad Zainuddin Hendra Dian Adhita Dharsono Meiny Faudah Amin Source Type: research
In silico Study of Antiviral Activity of Polyphenol Compounds from < em > Ocimum basilicum < /em > by Molecular Docking, ADMET, and Drug-Likeness Analysis
CONCLUSION: Based on the data obtained, Apigenin-7-glucuronide and dihydrokaempferol-3-glucoside are compounds that have more potential to have an antiviral effect on the main protease enzyme than aesculetin. Based on pharmacokinetic parameters and drug-likeness, three compounds can be used as lead compounds for further research.PMID:37131997 | PMC:PMC10149097 | DOI:10.2147/AABC.S403175 (Source: Adv Data)
Source: Adv Data - May 3, 2023 Category: Epidemiology Authors: Dikdik Kurnia Salsabila Aqila Putri Sefren Geiner Tumilaar Achmad Zainuddin Hendra Dian Adhita Dharsono Meiny Faudah Amin Source Type: research
Evaluation of the Anticancer Potential of < em > Morus nigra < /em > and < em > Ocimum basilicum < /em > Mixture against Different Cancer Cell Lines: An In Vitro Evaluation
Biomed Res Int. 2023 Apr 19;2023:9337763. doi: 10.1155/2023/9337763. eCollection 2023.ABSTRACTMorus nigra (M) and Ocimum basilicum (O) mixture (MO2) extract was extracted using hexane (MO2H), chloroform (MO2C), ethyl acetate (MO2E), and methanol (MO2M) in a Soxhlet apparatus. The cytotoxicity was evaluated using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay. The IC50 values of the MO2C-treated cancer cells were 11.31 μg/mL (MDA-MB-231), 15.45 μg/mL (MCF-7), 18.9 μg/mL (HepG2), 26.33 μg/mL (Huh-7), 30.17 μg/mL (LoVo), and 36.76 μg/mL (HCT116). MO2C-treated cells showed cellular and nuclear ...
Source: Cell Research - May 1, 2023 Category: Cytology Authors: Bader O Almutairi Ahmed I Alsayadi Nael Abutaha Fahd A Al-Mekhlafi Mohamed A Wadaan Source Type: research
