Evaluation of the Anticancer Potential of < em > Morus nigra < /em > and < em > Ocimum basilicum < /em > Mixture against Different Cancer Cell Lines: An In Vitro Evaluation
Biomed Res Int. 2023 Apr 19;2023:9337763. doi: 10.1155/2023/9337763. eCollection 2023.ABSTRACTMorus nigra (M) and Ocimum basilicum (O) mixture (MO2) extract was extracted using hexane (MO2H), chloroform (MO2C), ethyl acetate (MO2E), and methanol (MO2M) in a Soxhlet apparatus. The cytotoxicity was evaluated using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay. The IC50 values of the MO2C-treated cancer cells were 11.31 μg/mL (MDA-MB-231), 15.45 μg/mL (MCF-7), 18.9 μg/mL (HepG2), 26.33 μg/mL (Huh-7), 30.17 μg/mL (LoVo), and 36.76 μg/mL (HCT116). MO2C-treated cells showed cellular and nuclear ...
Source: Biomed Res - May 1, 2023 Category: Research Authors: Bader O Almutairi Ahmed I Alsayadi Nael Abutaha Fahd A Al-Mekhlafi Mohamed A Wadaan Source Type: research

Ameliorative effect of extracts from scent (Ocimum basilicum), mentha (Mentha piperita), and thyme (Thymus vulgaris) leafy spices on glycemic, purinergic molecules, and oxidative status in renal tissue of diabetic rats
In conclusion, the oral administration of extracts from the studied leafy spices could have beneficial effects against diabetic nephropathy. (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - April 28, 2023 Category: Pathology Source Type: research

Genes, Vol. 14, Pages 955: On the Future Perspectives of Some Medicinal Plants within Lamiaceae Botanic Family Regarding Their Comprehensive Properties and Resistance against Biotic and Abiotic Stresses
Brezeanu Lamiaceae is one of the largest botanical families, encompassing over 6000 species that include a variety of aromatic and medicinal spices. The current study is focused on three plants within this botanical family: basil (Ocimum basilicum L.), thyme (Thymus vulgaris L.), and summer savory (Satureja hortensis L.). These three species contain primary and secondary metabolites such as phenolic and flavonoid compounds, fatty acids, antioxidants, and essential oils and have traditionally been used for flavoring, food preservation, and medicinal purposes. The goal of this study is to provide an overview of the nutr...
Source: Genes - April 22, 2023 Category: Genetics & Stem Cells Authors: Dan Ioan Avasiloaiei Mariana Calara Petre Marian Brezeanu Otilia Cristina Murariu Creola Brezeanu Tags: Review Source Type: research

Green nanotechnology advances: green manufacturing of zinc nanoparticles, characterization, and foliar application on wheat and antibacterial characteristics using Mentha spicata (mint) and Ocimum basilicum (basil) leaf extracts
Environ Sci Pollut Res Int. 2023 Apr 11. doi: 10.1007/s11356-023-26827-3. Online ahead of print.ABSTRACTDue to their distinctive characteristics and widespread application across all scientific disciplines, nanoparticles have attracted a lot of attention in the current millennium. Green synthesis of ZnO-NPs is gaining a lot of interest at the moment due to a number of its advantages over traditional methods, including being quicker, less expensive, and more environmentally friendly. In the current study, two distinct plant extracts are used to quickly, cheaply, and environmentally friendly synthesize zinc oxide nanoparticl...
Source: Environmental Science and Pollution Research International - April 11, 2023 Category: Environmental Health Authors: Zeynep G örkem Doğaroğlu Ya ğmur Uysal Zehranur Çaylalı Delil Sefkan Karakulak Source Type: research

Molecules, Vol. 28, Pages 3305: Effect of Microencapsulated Basil Extract on Cream Cheese Quality and Stability
Rodica Sturza The antimicrobial and antioxidant effects of plant extracts are well known, but their use is limited because they affect the physicochemical and sensory characteristics of products. Encapsulation presents an option to limit or prevent these changes. The paper presents the composition of individual polyphenols (HPLC&amp;ndash;DAD-ESI-MS) from basil (Ocimum basilicum L.) extracts (BE), and their antioxidant activity and inhibitory effects against strains of Staphylococcus aureus, Geobacillus stearothermophilus, Bacillus cereus, Candida albicans, Enterococcus faecalis, Escherichia coli, and Salmonella...
Source: Molecules - April 7, 2023 Category: Chemistry Authors: Liliana Popescu Daniela Cojocari Ildiko Lung Irina Kacso Alexandra Cior îţă Aliona Ghendov-Mosanu Greta Balan Adela Pintea Rodica Sturza Tags: Article Source Type: research

Assessment of The Antibacterial Susceptibility of Ocimum basilicum
Cell Mol Biol (Noisy-le-grand). 2022 Aug 31;68(8):96-101. doi: 10.14715/cmb/2022.68.8.17.ABSTRACT The current study was designed to assess the antibacterial activities of an ethanol extract of Ocimum basilicum (O. basilicum). Using disc diffusion and direct contact methods, the extracts were tested in vitro against three bacterial strains. The direct contact test was used and compared with the agar diffusion test. The optical density was measured using a spectrophotometer to collect data. The results showed that methanol extracts of plant parts of O. basilcum leaves contained tannins, flavonoids, glycosides, and steroids, ...
Source: Cellular and Molecular Biology - February 21, 2023 Category: Molecular Biology Authors: Sulaiman Alsalamah Mohamed I Algonuim Nosiba Basher Abdel Moneim E Sulieman Source Type: research