The Interference Mechanism of Basil Essential Oil on the Cell Membrane Barrier and Respiratory Metabolism of Listeria monocytogenes
This article takes basil (Ocimum basilicum L.) essential oil (BEO) as the research object and explores its antibacterial mechanism against L. monocytogenes. The site of action was preliminarily determined to provide a theoretical basis for the development of natural antibacterial agents. The results show that BEO has good antibacterial activity against L. monocytogenes. After 8 h of treatment with BEO (1 mg/ml), the number of remaining bacteria reached an undetectable level. Combining spectroscopic analysis techniques (Raman, UV, and fluorescence spectroscopy) and fluorescence microscopy imaging techniques, it was foun...
Source: Frontiers in Microbiology - April 1, 2022 Category: Microbiology Source Type: research

Molecules, Vol. 27, Pages 1456: Antimicrobial and Larvicidal Activities of Different Ocimum Essential Oils Extracted by Ultrasound-Assisted Hydrodistillation
This study analyzed the possible use of UAE- Essential oils (EOs) from different species of Ocimum plants (Ocimum basilicum (OB), O. gratissimum (OG), O. tenuiflorum (OT), and O. canum (OC)) in the management of microbial pathogens and mosquito larval control. The antibacterial activity was estimated in terms of a disc diffusion assay and minimum inhibitory concentrations against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella enteritidis. The larvicidal property was found using three important mosquito vectors and the LC50 value was determined. Furthermore, antioxidant and anti-inflammatory...
Source: Molecules - February 22, 2022 Category: Chemistry Authors: Kuzhimbattil Sneha Arunaksharan Narayanankutty Joice Tom Job Opeyemi Joshua Olatunji Ahmed Alfarhan Ademola C. Famurewa Varsha Ramesh Tags: Article Source Type: research

Molecules, Vol. 27, Pages 1388: Ocimum basilicum L. Methanol Extract Enhances Mitochondrial Efficiency and Decreases Adipokine Levels in Maturing Adipocytes Which Regulate Macrophage Systemic Inflammation
llah Alshatwi Excessive storage of lipids in visceral or ectopic sites stimulates adipokine production, which attracts macrophages. This process determines the pro- and anti-inflammatory response regulation in adipose tissue during obesity-associated systemic inflammation. The present study aimed to identify the composition of Ocimum basilicum L. (basil) seed extract and to determine its bio-efficacy on adipocyte thermogenesis or fatty acid oxidation and inhibition of lipid accumulation and adipokine secretion. Ocimum basilicum L. seed methanol extract (BSME) was utilized to analyze the cytotoxicity vs. control; lipid ...
Source: Molecules - February 18, 2022 Category: Chemistry Authors: Pandurangan Subash-Babu Hussah Mohammed Mohammed Alowaidh Laila Naif Al-Harbi Ghalia Shamlan Amal A. Aloud Sahar Abdulaziz AlSedairy Ali Abdullah Alshatwi Tags: Article Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Herbal Approaches in the Management of Mental Depression
CONCLUSION: Potential compounds isolated from medicinal plants for the treatment of depression disorders need to be established.Herbal plant research could aid in this endeavour.PMID:35088681 | DOI:10.2174/1871527321666220128091408 (Source: CNS and Neurological Disorders Drug Targets)
Source: CNS and Neurological Disorders Drug Targets - January 28, 2022 Category: Drugs & Pharmacology Authors: Preeti Garg Jyoti Alambayan Vandana Garg Source Type: research

Ocimum basilicum Essential Oil Modulates Hematotoxicity, Oxidative Stress, DNA Damage, and Cell Cycle Arrest Induced by β-cyfluthrin in Rat Liver
Pesticides are used in large quantities infrequently, resulting in environmental damage and health issues. The goal of the current study was to explore the ameliorating effect of Ocimum basilicum (Basil) leaves essential oil versus the harmful effects of β-cyfluthrin in rat liver. Male Wistar rats were classified at random into four groups; negative control (corn oil), basil leaves essential oil (BEO, 3 ml/kg), β-cyfluthrin (positive control) (β-Cyf; 15 mg/kg BW, 1/25 LD50), and BEO plus β-Cyf, respectively. The rats were given their doses orally every day for a month. Results revealed that BEO yielded 6.32 mg/g wit...
Source: Frontiers in Pharmacology - January 21, 2022 Category: Drugs & Pharmacology Source Type: research

Antibacterial and antibiofilm activities of chitosan nanoparticles loaded with Ocimum basilicum L. essential oil
In this study, Ocimum basilicum L. essential oil (BEO) was encapsulated into chitosan nanoparticles by emulsion and ionic gelation. The success of BEO loading was revealed by Fourier transform infrared (FTIR) spectroscopy, ultraviolet visible spectrophotometry and X-ray diffraction (XRD) analyses. Scanning electron microscopy (SEM) images and dynamic light scattering (DLS) illustrated regular distribution and spherical morphology with a particle size range of 198.7-373.4 nm. The prepared samples had an encapsulation efficiency (EE) range of 50.39-5.13% and a loading capacity (LC) range of 7.22-19.78%. Encapsulation of BEO ...
Source: International Journal of Biological Macromolecules - January 18, 2022 Category: Biochemistry Authors: Mingdi Cai Yiting Wang Ru Wang Miaomiao Li Wei Zhang Jicheng Yu Ruinian Hua Source Type: research

Antibacterial and antibiofilm activities of chitosan nanoparticles loaded with Ocimum basilicum L. essential oil
In this study, Ocimum basilicum L. essential oil (BEO) was encapsulated into chitosan nanoparticles by emulsion and ionic gelation. The success of BEO loading was revealed by Fourier transform infrared (FTIR) spectroscopy, ultraviolet visible spectrophotometry and X-ray diffraction (XRD) analyses. Scanning electron microscopy (SEM) images and dynamic light scattering (DLS) illustrated regular distribution and spherical morphology with a particle size range of 198.7-373.4 nm. The prepared samples had an encapsulation efficiency (EE) range of 50.39-5.13% and a loading capacity (LC) range of 7.22-19.78%. Encapsulation of BEO ...
Source: International Journal of Biological Macromolecules - January 18, 2022 Category: Biochemistry Authors: Mingdi Cai Yiting Wang Ru Wang Miaomiao Li Wei Zhang Jicheng Yu Ruinian Hua Source Type: research