Experimental accumulation and depuration kinetics and natural occurrence of microcystin-LR in basil (Ocimum basilicum L.)
Environ Pollut. 2024 Mar 8:123715. doi: 10.1016/j.envpol.2024.123715. Online ahead of print.ABSTRACTMicrocystin-LR (MC-LR) is a hepatotoxic metabolite that naturally occurs during some cyanobacterial blooms in eutrophic waterbodies, and irrigation of edible plants with MC-LR-contaminated water causes bioaccumulation of the toxin. However, sufficient information about accumulation and depuration mechanics in hydroculture-grown herb plants is still lacking. This work aimed at 1) investigating bioaccumulation and depuration of MC-LR in basil, 2) verifying the possible MC-LR detoxification mechanisms in the plant, and 3) detec...
Source: Environmental Pollution - March 10, 2024 Category: Environmental Health Authors: Wannes Hugo R Van Hassel Mohamed F Abdallah Maria Gracia Guzman Velasquez Christopher O Miles Ingunn A Samdal Julien Masquelier Andreja Rajkovic Source Type: research
Experimental accumulation and depuration kinetics and natural occurrence of microcystin-LR in basil (Ocimum basilicum L.)
Environ Pollut. 2024 Mar 8:123715. doi: 10.1016/j.envpol.2024.123715. Online ahead of print.ABSTRACTMicrocystin-LR (MC-LR) is a hepatotoxic metabolite that naturally occurs during some cyanobacterial blooms in eutrophic waterbodies, and irrigation of edible plants with MC-LR-contaminated water causes bioaccumulation of the toxin. However, sufficient information about accumulation and depuration mechanics in hydroculture-grown herb plants is still lacking. This work aimed at 1) investigating bioaccumulation and depuration of MC-LR in basil, 2) verifying the possible MC-LR detoxification mechanisms in the plant, and 3) detec...
Source: Environmental Pollution - March 10, 2024 Category: Environmental Health Authors: Wannes Hugo R Van Hassel Mohamed F Abdallah Maria Gracia Guzman Velasquez Christopher O Miles Ingunn A Samdal Julien Masquelier Andreja Rajkovic Source Type: research
Sweet basil (Ocimum basilicum) leaf and seed extracts alleviate neuronal dysfunction in aluminum chloride-induced neurotoxicity in Drosophila melanogaster Meigen model
. (Source: Drug and Chemical Toxicology)
Source: Drug and Chemical Toxicology - March 4, 2024 Category: Toxicology Authors: Olubukola H. OyeniranFamusiwa D. CourageAdedayo O. AdemiluyiGaniyu Oboha Phytomedicine and Molecular Toxicology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Ekiti State, Nigeriab Functional Foods, Nutraceuticals and Phyto Source Type: research
Construction of viral-based expression vectors for high-level production of human interferon alpha 2b in plants
Appl Microbiol Biotechnol. 2024 Feb 23;108(1):229. doi: 10.1007/s00253-024-13069-7.ABSTRACTHuman interferon (hINF) alpha 2b is clinically important pharmaceutical product included in combinatory therapy against chronic hepatitis C and B and complex therapy against several cancer diseases. Here, we created the genetic constructions, based on genome elements of potato virus X (PVX), carrying the infα2b gene for transient expression in plant cells. The created plasmid vector constructions were tested through Agrobacterium-mediated transient gene expression method in two plant species-Nicotiana benthamiana and Ocimum basilicu...
Source: Applied Microbiology and Biotechnology - February 23, 2024 Category: Microbiology Authors: Yana Sindarovska Mykola Kuchuk Source Type: research
Molecules, Vol. 29, Pages 901: Bioaccessibility of Rosmarinic Acid and Basil (Ocimum basilicum L.) Co-Compounds in a Simulated Digestion Model & mdash;The Influence of the Endogenous Plant Matrix, Dose of Administration and Physicochemical and Biochemical Digestion Environment
In conclusion, the determination of the bioaccessibility of bioactive phytochemicals from basil and factors influencing bioaccessibility may help in better prediction of the pro-health potential of this plant. (Source: Molecules)
Source: Molecules - February 18, 2024 Category: Chemistry Authors: Łukasz Sęczyk Barbara Ko łodziej Tags: Article Source Type: research
The biochemical and growth-associated traits of basil (Ocimum basilicum L.) affected by silver nanoparticles and silver
The biochemical and growth changes resulting from exposure of basil (Ocimum basilicum L.) seedlings to silver nanoparticles and silver were investigated. Over a two-week period, seedlings were exposed to differen... (Source: BMC Plant Biology)
Source: BMC Plant Biology - February 6, 2024 Category: Biology Authors: Shahla Hashemi Shahraki, Tayebeh Ahmadi, Babak Jamali and Mehdi Rahimi Tags: Research Source Type: research
Molecules, Vol. 29, Pages 388: Antimicrobial and Other Pharmacological Properties of Ocimum basilicum, Lamiaceae
limova
Zhanylsyn Karasova
Since ancient times, various scientists and doctors have utilized different herbs to heal diseases. Due to the rise in drug resistance and the negative effects of chemosynthetic drugs, researchers and the general public around the world have become more interested in medicinal herbs and plant metabolites/extracts. This is due to its non-toxicity and its several health benefits when used to treat diseases in clinical and medical settings. Ocimum basilicum is one such plant, possessing a wide range of bioactive phytochemicals including alkaloids, phenolics, flavonoids, tannins, saponins, reduc...
Source: Molecules - January 12, 2024 Category: Chemistry Authors: Kairat Zhakipbekov Aknur Turgumbayeva Sholpan Akhelova Kymbat Bekmuratova Olga Blinova Gulnara Utegenova Klara Shertaeva Nurlan Sadykov Kuanysh Tastambek Akzharkyn Saginbazarova Kenzhebek Urazgaliyev Gulbanu Tulegenova Zere Zhalimova Zhanylsyn Karasova Tags: Review Source Type: research
Insights of phytoremediation mechanisms for viruses based on in-vitro, in-vivo and in-silico assessments of selected herbal plants
This study investigated antiviral mechanisms in-vivo using bacteriophages MS2 and T4 as surrogates for effective herbs screened in-vitro from three embryophytes (Ocimum basilicum, Mentha sp., Plectranthus amboinicus), two macrophytes (Eichhornia crassipes, Pistia stratiotes) and a perennial grass (Cyperus rotundas). In-silico virtual screening predicted antiviral phytochemicals for further antiviral potency assessment. Results suggested in-vitro antiviral activities of embryophytes and macrophytes were higher (43-62%) than grass (21-26%). O. basilicum (OB, 57-62%) and P. stratiotes (PS, 59-60%) exhibited the highest antivi...
Source: Chemosphere - January 3, 2024 Category: Chemistry Authors: Diaiti Zure Hsion-Wen David Kuo Aleksandra Drizo Source Type: research
Insights of phytoremediation mechanisms for viruses based on in-vitro, in-vivo and in-silico assessments of selected herbal plants
This study investigated antiviral mechanisms in-vivo using bacteriophages MS2 and T4 as surrogates for effective herbs screened in-vitro from three embryophytes (Ocimum basilicum, Mentha sp., Plectranthus amboinicus), two macrophytes (Eichhornia crassipes, Pistia stratiotes) and a perennial grass (Cyperus rotundas). In-silico virtual screening predicted antiviral phytochemicals for further antiviral potency assessment. Results suggested in-vitro antiviral activities of embryophytes and macrophytes were higher (43-62%) than grass (21-26%). O. basilicum (OB, 57-62%) and P. stratiotes (PS, 59-60%) exhibited the highest antivi...
Source: Chemosphere - January 3, 2024 Category: Chemistry Authors: Diaiti Zure Hsion-Wen David Kuo Aleksandra Drizo Source Type: research
Antioxidant and Protective Effect of Ocimum basilicum Seeds Extract on Renal Toxicity Induced by Carbon Tetrachloride in Rats
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - December 26, 2023 Category: Nutrition Authors: Fatma Ben Mansour Habib Ayadi Jos van Pelt Abdelfattah Elfeki Khaled Bellassoued Source Type: research
Low-temperature perception and modulations in Ocimum basilicum commercial cultivar CIM-Shishir : biosynthetic potential with insight towards climate-smart resilience
In this study, we subjected both the CIM-Shishir variety and a control plant to cold stress to investigate the impact of low temperatures on various physiological, trichome developments, secondary metabolite constitution aspects related to essential oil production, and gene expression. The analysis revealed a significantly higher density and altered morphology of trichomes on the leaf surface of the variety subjected to low temperatures, indicating its adaptation to cold conditions. Furthermore, when comparing the treated plants under low-temperature stress, it was observed that the relative electrolyte leakage and Malondi...
Source: Gene - November 30, 2023 Category: Genetics & Stem Cells Authors: Pankhuri Gupta Sunita Singh Dhawan R K Lal Anand Mishra C S Chanotiya Source Type: research
Ethanol extract of basil ( < em > Ocimum Basilicum < /em > L.) leaves inhibits endometriosis growth in a mouse model by modulating vascular endothelial growth factor (VEGF) expression
The objective of this study was to examine the effect of administering an ethanol extract obtained from basil leaves on the expression of vascular endothelial growth factor (VEGF) and the severity of endometriosis lesions in a mouse model. A total of 28 female mice, aged 2-3 months and weighing 20-30 grams, were randomly divided into four groups: the control group (C), treatment group 1 (T1) receiving a dose of basil leaf ethanol extract (0.21 mg/g-BW), treatment group 2 (T2) receiving a higher dose (0.42 mg/g BW), and treatment group 3 (T3) receiving the highest dose (0.84 mg/g-BW). Each group underwent a 14-day treatment...
Source: Journal of Medicine and Life - November 29, 2023 Category: General Medicine Authors: Dewi Qurotul A'yuni Ashon Sa'adi Widjiati Widjiati Source Type: research
