Comparison of clinical outcomes in critically ill COVID-19 patients on mechanical ventilation with nosocomial pneumonia between Alpha and Omicron variants
CONCLUSION: Our study discovered a higher in-hospital mortality rate in severe COVID-19 patients with MV and secondary pneumonia infected with the Omicron variant compared to the Alpha variant; however, real independent risk factors for in-hospital mortality are malignancy, lower serum albumin level, and lack of Remdesivir treatment.PMID:38018405 | DOI:10.1177/17534666231213642 (Source: Respiratory Care)
Source: Respiratory Care - November 29, 2023 Category: Respiratory Medicine Authors: Chuan-Yen Sun Jhong-Ru Huang Hsiao-Chin Shen Ying-Ting Liao Hung-Jui Ko Chih-Jung Chang Yuh-Min Chen Jia-Yih Feng Wei-Chih Chen Kuang-Yao Yang Source Type: research
Comparison of clinical outcomes in critically ill COVID-19 patients on mechanical ventilation with nosocomial pneumonia between Alpha and Omicron variants
CONCLUSION: Our study discovered a higher in-hospital mortality rate in severe COVID-19 patients with MV and secondary pneumonia infected with the Omicron variant compared to the Alpha variant; however, real independent risk factors for in-hospital mortality are malignancy, lower serum albumin level, and lack of Remdesivir treatment.PMID:38018405 | DOI:10.1177/17534666231213642 (Source: Adv Data)
Source: Adv Data - November 29, 2023 Category: Epidemiology Authors: Chuan-Yen Sun Jhong-Ru Huang Hsiao-Chin Shen Ying-Ting Liao Hung-Jui Ko Chih-Jung Chang Yuh-Min Chen Jia-Yih Feng Wei-Chih Chen Kuang-Yao Yang Source Type: research
Comparison of clinical outcomes in critically ill COVID-19 patients on mechanical ventilation with nosocomial pneumonia between Alpha and Omicron variants
CONCLUSION: Our study discovered a higher in-hospital mortality rate in severe COVID-19 patients with MV and secondary pneumonia infected with the Omicron variant compared to the Alpha variant; however, real independent risk factors for in-hospital mortality are malignancy, lower serum albumin level, and lack of Remdesivir treatment.PMID:38018405 | PMC:PMC10685785 | DOI:10.1177/17534666231213642 (Source: Respiratory Care)
Source: Respiratory Care - November 29, 2023 Category: Respiratory Medicine Authors: Chuan-Yen Sun Jhong-Ru Huang Hsiao-Chin Shen Ying-Ting Liao Hung-Jui Ko Chih-Jung Chang Yuh-Min Chen Jia-Yih Feng Wei-Chih Chen Kuang-Yao Yang Source Type: research
Severe Bacterial Pneumonia due to Legionella longbeachae Transmitted from Potting Soil in Japan
Intern Med. 2023 Nov 27. doi: 10.2169/internalmedicine.2590-23. Online ahead of print.ABSTRACTPneumonia caused by Legionella longbeachae, transmitted through contaminated soil, is very rare in Japan. A 70-year-old man with severe respiratory failure was admitted to our hospital and underwent multidisciplinary procedures. Although a urinary antigen test was negative for Legionella, he was clinically diagnosed with legionellosis and administered levofloxacin. His condition subsequently improved. Thereafter, sputum culture detected L. longbeachae. Because the DNA of L. longbeachae was detected in the gardening soil, it is sus...
Source: Internal Medicine - November 26, 2023 Category: Internal Medicine Authors: Hidemi Ogawa Kenichiro Takeda Ryotaro Yoneoka Kohei Shikano Mitsuhiro Abe Hajime Kasai Takuji Suzuki Source Type: research
Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an ARDS Model
Conclusions: These data indicate that specific Orai1 inhibition by ELD607 may be a novel approach to reduce multi-organ inflammation and treat antibiotic-resistant bacteria.PMID:37972349 | DOI:10.1164/rccm.202308-1393OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - November 16, 2023 Category: Respiratory Medicine Authors: Saira Ahmad Joe A Wrennall Alexandra S Goriounova Malika Sekhri Jason A Iskarpatyoti Arunava Ghosh Sabri H Abdelwahab Alexis Voeller Mani Rai Rahul Y Mahida Krzysztof Krajewski Diane M Ignar Alon Greenbaum Timothy P Moran Stephen L Tilley David R Thickett Source Type: research
Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an ARDS Model
Conclusions: These data indicate that specific Orai1 inhibition by ELD607 may be a novel approach to reduce multi-organ inflammation and treat antibiotic-resistant bacteria.PMID:37972349 | DOI:10.1164/rccm.202308-1393OC (Source: Respiratory Care)
Source: Respiratory Care - November 16, 2023 Category: Respiratory Medicine Authors: Saira Ahmad Joe A Wrennall Alexandra S Goriounova Malika Sekhri Jason A Iskarpatyoti Arunava Ghosh Sabri H Abdelwahab Alexis Voeller Mani Rai Rahul Y Mahida Krzysztof Krajewski Diane M Ignar Alon Greenbaum Timothy P Moran Stephen L Tilley David R Thickett Source Type: research
Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an ARDS Model
Conclusions: These data indicate that specific Orai1 inhibition by ELD607 may be a novel approach to reduce multi-organ inflammation and treat antibiotic-resistant bacteria.PMID:37972349 | DOI:10.1164/rccm.202308-1393OC (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - November 16, 2023 Category: Intensive Care Authors: Saira Ahmad Joe A Wrennall Alexandra S Goriounova Malika Sekhri Jason A Iskarpatyoti Arunava Ghosh Sabri H Abdelwahab Alexis Voeller Mani Rai Rahul Y Mahida Krzysztof Krajewski Diane M Ignar Alon Greenbaum Timothy P Moran Stephen L Tilley David R Thickett Source Type: research
Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an ARDS Model
Conclusions: These data indicate that specific Orai1 inhibition by ELD607 may be a novel approach to reduce multi-organ inflammation and treat antibiotic-resistant bacteria.PMID:37972349 | DOI:10.1164/rccm.202308-1393OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - November 16, 2023 Category: Respiratory Medicine Authors: Saira Ahmad Joe A Wrennall Alexandra S Goriounova Malika Sekhri Jason A Iskarpatyoti Arunava Ghosh Sabri H Abdelwahab Alexis Voeller Mani Rai Rahul Y Mahida Krzysztof Krajewski Diane M Ignar Alon Greenbaum Timothy P Moran Stephen L Tilley David R Thickett Source Type: research
