Etiology and Clinical Characteristics of Community-Acquired Pneumonia in Korean Children During the Pre-COVID-19 Period, 2015-2020
CONCLUSION: M. pneumoniae and RSV were the most commonly detected pathogens of pediatric CAP, which was selected by strict clinical and radiologic criteria. It is necessary to carefully decide whether to use parenteral antibiotics based on the epidemiology and clinical features of CAP in children.PMID:37935166 | PMC:PMC10627724 | DOI:10.3346/jkms.2023.38.e339 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 7, 2023 Category: Biomedical Science Authors: Jung Ho Suh Bin Ahn Seung Ha Song Sujin Choi Sung Hwan Choi Hyunju Lee Mi Seon Han Ji Young Park Eun Hwa Choi Ki Wook Yun Source Type: research
Etiology and Clinical Characteristics of Community-Acquired Pneumonia in Korean Children During the Pre-COVID-19 Period, 2015-2020
CONCLUSION: M. pneumoniae and RSV were the most commonly detected pathogens of pediatric CAP, which was selected by strict clinical and radiologic criteria. It is necessary to carefully decide whether to use parenteral antibiotics based on the epidemiology and clinical features of CAP in children.PMID:37935166 | PMC:PMC10627724 | DOI:10.3346/jkms.2023.38.e339 (Source: J Korean Med Sci)
Source: J Korean Med Sci - November 7, 2023 Category: General Medicine Authors: Jung Ho Suh Bin Ahn Seung Ha Song Sujin Choi Sung Hwan Choi Hyunju Lee Mi Seon Han Ji Young Park Eun Hwa Choi Ki Wook Yun Source Type: research
Etiology and Clinical Characteristics of Community-Acquired Pneumonia in Korean Children During the Pre-COVID-19 Period, 2015-2020
CONCLUSION: M. pneumoniae and RSV were the most commonly detected pathogens of pediatric CAP, which was selected by strict clinical and radiologic criteria. It is necessary to carefully decide whether to use parenteral antibiotics based on the epidemiology and clinical features of CAP in children.PMID:37935166 | PMC:PMC10627724 | DOI:10.3346/jkms.2023.38.e339 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 7, 2023 Category: Biomedical Science Authors: Jung Ho Suh Bin Ahn Seung Ha Song Sujin Choi Sung Hwan Choi Hyunju Lee Mi Seon Han Ji Young Park Eun Hwa Choi Ki Wook Yun Source Type: research
Etiology and Clinical Characteristics of Community-Acquired Pneumonia in Korean Children During the Pre-COVID-19 Period, 2015-2020
CONCLUSION: M. pneumoniae and RSV were the most commonly detected pathogens of pediatric CAP, which was selected by strict clinical and radiologic criteria. It is necessary to carefully decide whether to use parenteral antibiotics based on the epidemiology and clinical features of CAP in children.PMID:37935166 | PMC:PMC10627724 | DOI:10.3346/jkms.2023.38.e339 (Source: J Korean Med Sci)
Source: J Korean Med Sci - November 7, 2023 Category: General Medicine Authors: Jung Ho Suh Bin Ahn Seung Ha Song Sujin Choi Sung Hwan Choi Hyunju Lee Mi Seon Han Ji Young Park Eun Hwa Choi Ki Wook Yun Source Type: research
Etiology and Clinical Characteristics of Community-Acquired Pneumonia in Korean Children During the Pre-COVID-19 Period, 2015-2020
CONCLUSION: M. pneumoniae and RSV were the most commonly detected pathogens of pediatric CAP, which was selected by strict clinical and radiologic criteria. It is necessary to carefully decide whether to use parenteral antibiotics based on the epidemiology and clinical features of CAP in children.PMID:37935166 | PMC:PMC10627724 | DOI:10.3346/jkms.2023.38.e339 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - November 7, 2023 Category: Biomedical Science Authors: Jung Ho Suh Bin Ahn Seung Ha Song Sujin Choi Sung Hwan Choi Hyunju Lee Mi Seon Han Ji Young Park Eun Hwa Choi Ki Wook Yun Source Type: research
A comprehensive segmentation of chest X-ray improves deep learning –based WHO radiologically confirmed pneumonia diagnosis in children
ConclusionsThe comprehensive segmentation of CXR could improve deep learning –based pneumonia diagnosis in childhood with a more reasonable WHO’s radiological standardized pneumonia classification instead of conventional dichotomous bacterial pneumonia and viral pneumonia.Clinical relevance statementThe comprehensive segmentation of chest X-ray improves deep learning –based WHO confirmed pneumonia diagnosis in children, laying a strong foundation for the potential inclusion of computer-aided pediatric CXR readings in precise classification of pneumonia and PCV vaccine trials efficacy in children.Key Points• The che...
Source: European Radiology - November 6, 2023 Category: Radiology Source Type: research
Clinical characteristics and risk factors associated with secondary bacterial pneumonia among COVID-19 patients in ICU
Conclusions: Secondary bacterial pneumonia was found to be associated with the severity and survival of the disease in patients admitted to ICU due to COVID-19. Duration of mechanical ventilation and use of corticosteroids and high-dose corticosteroids are risk factors for secondary bacterial pneumonia. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - October 31, 2023 Category: Infectious Diseases Authors: Insa G ül Ekiz Iscanli, Mehtap Aydin, Bengü Şaylan Source Type: research
Bevacizumab in addition to standard of care did not shorten the time to improve hypoxemia in severe hypoxemic COVID-19 pneumonia in a prospective randomized controlled trial.
Conclusions Addition of BEV to SoC did not shorten the time to improve hypoxemia in severe COVID-19 pneumonia, as compared with Soc. Deaths were numerically lower in BEV. No negative safety signal was observed. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Cadranel, J., Rolland-Debord, C., Labbe, V., Tuffet, S., Planquette, B., Teboul, J.-L., Jouffroy, R., Guidet, B., Voiriot, G., Hindre, R., Saval, L., Schmidt, J., Darmon, M., Marey, J., Mekontso-Dessap, A., Taille, C., Giroux-Leprieur, E., Geny, F., Mayau Tags: Respiratory infections and bronchiectasis Source Type: research
LSC - 2023 - Longitudinal proteomic profiling reveals early onset increase in collagens and (auto-)antibodies in COVID-19 patients
Infectious respiratory diseases comprise the 4th most fatal group of diseases worldwide. Most studies on COVID-19 lack appropriate comparison to other viral pneumonias with similar severity. Here, we leverage the SCRIPT cohort at NWU Chicago for longitudinal proteomic profiling of bronchoalveolar lavage fluid (BALF) and patient plasma to analyze pathogen-specific differences during disease progression. We used mass spectrometry to analyze BALF and matched plasma from COVID-19 (n=14), bacterial pneumonia (n=8), influenza (n=8) patients, and non-pneumonia controls (n=8) at up to five time points after intubation in...
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Semenova, A., Poor, T. A., Geyer, P., Yildirim, A. O., Kapellos, T. S., Misharin, A. V., Budinger, G. S., Schiller, H. B. Tags: Respiratory infections and bronchiectasis Source Type: research
Detection of respiratory viruses in patients with aspiration pneumonia: a retrospective study
In conclusion, a significant number of respiratory virus infections were included in clinically diagnosed aspiration pneumonia patients. Differentiating respiratory virus infection from aspiration pneumonia was difficult. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Nabeya, D., Kinjo, T., Arakaki, W., Kami, W., Hashioka, H., Nishiyama, N., Kishaba, T., Yamamoto, K. Tags: Respiratory infections and bronchiectasis Source Type: research
Evaluating the utility of a serum calprotectin lateral flow test in acute lung infection
Conclusion: Serum calprotectin LFT and ELISA were comparable and moderately associated with neutrophil activation and clinical outcomes. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Gilmour, A., Hughes, C., Long, M. B., Keir, H. R., Giam, Y. H., Abo-Leyah, H., Pembridge, T., Delgado, L., Hull, R. C., New, B. J., Dowey, R., Turton, H., Condliffe, A. M., Chalmers, J. D., Thompson, A. A. R. Tags: Respiratory infections and bronchiectasis Source Type: research
Ferritin to Procalcitonin (F/P) ratio in patients with COVID19 pneumonia versus bacterial pneumonia. Do we have a reliable and challenging biomarker?
Conclusion: F/P ratio could be used as one of the biomarkers for distinguish COVID from bacterial pneumonia. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Dmitrovic, R. Tags: Respiratory infections and bronchiectasis Source Type: research
Lung contusion due to military chest injury as a risk factor for bacterial pneumonia and other respiratory infections.
The epidemic of gunshot wounds and injuries as a result of the war with Russia continues to grow. From February 24, 2022 to February 18, 2023, in the Pulmonology Department of Volyn Regional Clinical Hospital, the rate of hospitalized military patients with chest injury due to mine-explosive wounds, shrapnel wounds, gunshot bullet wounds, and stub-cut wounds of the chest amounted to 19.3% of all pulmonological diseases in the soldiers that were received during this year (n=88). Penetrating chest injury occurred in 41.1% of cases, non-penetrating blunt chest injury (including behind armor blunt trauma) in 23.5% of cases, ch...
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Yakovenko, O., Khodosh, E., Hrytsiuk, I., Yakovenko, T. Tags: Respiratory infections and bronchiectasis Source Type: research
Early-life dysbiosis increases airway hyperresponsiveness in mice
Epidemiological studies in humans correlate perinatal dysbiosis with increased long-term asthma severity. However, these studies suffer from high variability of dysbiotic causes (e.g. birth mode, breastfeeding, antibiotic treatment (AbT)). Further, the time window of these factors influencing asthma remains undefined. Given that maternal antibiotic exposure in mice increases the risk of newborn bacterial pneumonia in offspring, we hypothesized that dysbiosis occurring immediately before birth, and shortly after birth, stimulates long-term immunological effects in the offspring leading to an aggravated asthma phenotype. To ...
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Shirdel, S., Mcalees, J. W., Wilburn, A. N., Laumonnier, Y., Rupp, J., Graspeuntner, S., König, P., Lewkowich, I. P., Schmudde, I. Tags: Allergy and immunology Source Type: research
