High cholesterol diet-induced testicular dysfunction in rats
CONCLUSIONS: Our results showed that a high-cholesterol diet adversely affected testosterone production and sperm progressive motility, possibly due to Leydig, Sertoli, and germ cell abnormalities.PMID:37596375 | DOI:10.1007/s42000-023-00472-4 (Source: Hormones)
Source: Hormones - August 18, 2023 Category: Endocrinology Authors: Luna Liu Meijie Zhang Fangjie Jiang Dandan Luo Shuang Liu Yu Su Qingbo Guan Chunxiao Yu Source Type: research
Stepwise mini-incision microdissection testicular sperm extraction in NOA patients with a history of cryptorchidism: a case –control study
ConclusionsIn conclusion, our study suggests that the stepwise mini-incision mTESE could be a promising approach for sperm retrieval in NOA men with a history of cryptorchidism. While the technique may potentially reduce operation time and surgical invasiveness, further research is needed to validate these findings on a larger scale. The results also suggest that age at orchidopexy may affect SRR and have important implications for the management of cryptorchidism. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - August 17, 2023 Category: Urology & Nephrology Source Type: research
CUA azoospermia guideline: An important resource for physicians
Can Urol Assoc J. 2023 Aug;17(8):241. doi: 10.5489/cuaj.8474.NO ABSTRACTPMID:37581554 | DOI:10.5489/cuaj.8474 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Matthew Roberts Source Type: research
2023 Canadian Urological Association guideline: Evaluation and management of azoospermia
Can Urol Assoc J. 2023 Aug;17(8):228-240. doi: 10.5489/cuaj.8445.NO ABSTRACTPMID:37581550 | DOI:10.5489/cuaj.8445 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Ryan Flannigan Borna Tadayon Najafabadi Philippe D Violette Keith Jarvi Premal Patel Phil Vu Bach Trustin Domes Armand Zini Ethan Grober Victor Mak Marc Anthony Fischer Peter Chan Kirk Lo Victor Chow Chris Wu John Grantmyre Genevieve Patry Peter N Schlege Source Type: research
New CUA guideline: A valuable reference for counselling men with azoospermia
Can Urol Assoc J. 2023 Aug;17(8):242. doi: 10.5489/cuaj.8472.NO ABSTRACTPMID:37581542 | DOI:10.5489/cuaj.8472 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Peter N Schlegel Source Type: research
Recovering Spermatogenesis By Protected Cryopreservation Using Metformin and Transplanting Spermatogonial Stem Cells Into Testis in an Azoospermia Mouse Model
Biopreserv Biobank. 2023 Aug 15. doi: 10.1089/bio.2022.0178. Online ahead of print.ABSTRACTCryopreservation and transplantation of spermatogonial stem cells (SSCs) may serve as a new method to restore male fertility in patients undergoing chemotherapy or radiotherapy. However, SSCs may be damaged during cryopreservation due to the production of reactive oxygen species (ROS). Therefore, different antioxidants have been used as protective agents. Studies have shown that metformin (MET) has antioxidant activity. The aim of this study was to assess the antioxidant and antiapoptotic effects of MET in frozen-thawed SSCs. In addi...
Source: Biopreservation and Biobanking - August 15, 2023 Category: Biomedical Science Authors: Alieh Bashghareh Tayebeh Rastegar Peyman Modarresi Shokoofeh Kazemzadeh Maryam Salem Azim Hedayatpour Source Type: research
CUA azoospermia guideline: An important resource for physicians
Can Urol Assoc J. 2023 Aug;17(8):241. doi: 10.5489/cuaj.8474.NO ABSTRACTPMID:37581554 | PMC:PMC10426429 | DOI:10.5489/cuaj.8474 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Matthew Roberts Source Type: research
2023 Canadian Urological Association guideline: Evaluation and management of azoospermia
Can Urol Assoc J. 2023 Aug;17(8):228-240. doi: 10.5489/cuaj.8445.NO ABSTRACTPMID:37581550 | PMC:PMC10426420 | DOI:10.5489/cuaj.8445 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Ryan Flannigan Borna Tadayon Najafabadi Philippe D Violette Keith Jarvi Premal Patel Phil Vu Bach Trustin Domes Armand Zini Ethan Grober Victor Mak Marc Anthony Fischer Peter Chan Kirk Lo Victor Chow Chris Wu John Grantmyre Genevieve Patry Peter N Schlege Source Type: research
New CUA guideline: A valuable reference for counselling men with azoospermia
Can Urol Assoc J. 2023 Aug;17(8):242. doi: 10.5489/cuaj.8472.NO ABSTRACTPMID:37581542 | PMC:PMC10426417 | DOI:10.5489/cuaj.8472 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Peter N Schlegel Source Type: research
Recovering Spermatogenesis By Protected Cryopreservation Using Metformin and Transplanting Spermatogonial Stem Cells Into Testis in an Azoospermia Mouse Model
Biopreserv Biobank. 2023 Aug 15. doi: 10.1089/bio.2022.0178. Online ahead of print.ABSTRACTCryopreservation and transplantation of spermatogonial stem cells (SSCs) may serve as a new method to restore male fertility in patients undergoing chemotherapy or radiotherapy. However, SSCs may be damaged during cryopreservation due to the production of reactive oxygen species (ROS). Therefore, different antioxidants have been used as protective agents. Studies have shown that metformin (MET) has antioxidant activity. The aim of this study was to assess the antioxidant and antiapoptotic effects of MET in frozen-thawed SSCs. In addi...
Source: Biopreservation and Biobanking - August 15, 2023 Category: Biomedical Science Authors: Alieh Bashghareh Tayebeh Rastegar Peyman Modarresi Shokoofeh Kazemzadeh Maryam Salem Azim Hedayatpour Source Type: research
CUA azoospermia guideline: An important resource for physicians
Can Urol Assoc J. 2023 Aug;17(8):241. doi: 10.5489/cuaj.8474.NO ABSTRACTPMID:37581554 | PMC:PMC10426429 | DOI:10.5489/cuaj.8474 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Matthew Roberts Source Type: research
2023 Canadian Urological Association guideline: Evaluation and management of azoospermia
Can Urol Assoc J. 2023 Aug;17(8):228-240. doi: 10.5489/cuaj.8445.NO ABSTRACTPMID:37581550 | PMC:PMC10426420 | DOI:10.5489/cuaj.8445 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Ryan Flannigan Borna Tadayon Najafabadi Philippe D Violette Keith Jarvi Premal Patel Phil Vu Bach Trustin Domes Armand Zini Ethan Grober Victor Mak Marc Anthony Fischer Peter Chan Kirk Lo Victor Chow Chris Wu John Grantmyre Genevieve Patry Peter N Schlege Source Type: research
New CUA guideline: A valuable reference for counselling men with azoospermia
Can Urol Assoc J. 2023 Aug;17(8):242. doi: 10.5489/cuaj.8472.NO ABSTRACTPMID:37581542 | PMC:PMC10426417 | DOI:10.5489/cuaj.8472 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Peter N Schlegel Source Type: research
CUA azoospermia guideline: An important resource for physicians
Can Urol Assoc J. 2023 Aug;17(8):241. doi: 10.5489/cuaj.8474.NO ABSTRACTPMID:37581554 | PMC:PMC10426429 | DOI:10.5489/cuaj.8474 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Matthew Roberts Source Type: research
2023 Canadian Urological Association guideline: Evaluation and management of azoospermia
Can Urol Assoc J. 2023 Aug;17(8):228-240. doi: 10.5489/cuaj.8445.NO ABSTRACTPMID:37581550 | PMC:PMC10426420 | DOI:10.5489/cuaj.8445 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - August 15, 2023 Category: Urology & Nephrology Authors: Ryan Flannigan Borna Tadayon Najafabadi Philippe D Violette Keith Jarvi Premal Patel Phil Vu Bach Trustin Domes Armand Zini Ethan Grober Victor Mak Marc Anthony Fischer Peter Chan Kirk Lo Victor Chow Chris Wu John Grantmyre Genevieve Patry Peter N Schlege Source Type: research
