Cancer risk and male Infertility: Unravelling predictive biomarkers and prognostic indicators
Clin Chim Acta. 2024 Apr 11:119670. doi: 10.1016/j.cca.2024.119670. Online ahead of print.ABSTRACTIn recent years, there has been a global increase in cases of male infertility. There are about 30 million cases of male infertility worldwide and male reproductive health is showing rapid decline in last few decades. It is now recognized as a potential risk factor for developing certain types of cancer, particularly genitourinary malignancies like testicular and prostate cancer. Male infertility is considered a potential indicator of overall health and an early biomarker for cancer. Cases of unexplained male factor infertilit...
Source: International Journal of Clinical Chemistry - April 13, 2024 Category: Chemistry Authors: Prabhakar Tiwari Anjali Yadav Meenakshi Kaushik Rima Dada Source Type: research
Cancer risk and male Infertility: Unravelling predictive biomarkers and prognostic indicators
Clin Chim Acta. 2024 Apr 11:119670. doi: 10.1016/j.cca.2024.119670. Online ahead of print.ABSTRACTIn recent years, there has been a global increase in cases of male infertility. There are about 30 million cases of male infertility worldwide and male reproductive health is showing rapid decline in last few decades. It is now recognized as a potential risk factor for developing certain types of cancer, particularly genitourinary malignancies like testicular and prostate cancer. Male infertility is considered a potential indicator of overall health and an early biomarker for cancer. Cases of unexplained male factor infertilit...
Source: International Journal of Clinical Chemistry - April 13, 2024 Category: Chemistry Authors: Prabhakar Tiwari Anjali Yadav Meenakshi Kaushik Rima Dada Source Type: research
Cancer risk and male Infertility: Unravelling predictive biomarkers and prognostic indicators
Clin Chim Acta. 2024 Apr 11:119670. doi: 10.1016/j.cca.2024.119670. Online ahead of print.ABSTRACTIn recent years, there has been a global increase in cases of male infertility. There are about 30 million cases of male infertility worldwide and male reproductive health is showing rapid decline in last few decades. It is now recognized as a potential risk factor for developing certain types of cancer, particularly genitourinary malignancies like testicular and prostate cancer. Male infertility is considered a potential indicator of overall health and an early biomarker for cancer. Cases of unexplained male factor infertilit...
Source: Clinical Prostate Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Prabhakar Tiwari Anjali Yadav Meenakshi Kaushik Rima Dada Source Type: research
Editorial: Ex vivo onco-testis microdissection
When a patient has a solitary testis, a testis mass, and azoospermia, this is the last possible time to obtain sperm from a patient for use in a biologic pregnancy. Options for treatment, in this case, are partial orchiectomy with in vivo testis microdissection or radical orchiectomy and ex vivo testis microdissection. The decision on what is best is based on shared decision-making with both surgeon and patient based on size of the mass, risk of recurrence with a partial orchiectomy, and the possibility of retaining enough te stis tissue for production of endogenous testosterone and possible spermatogenesis. (Source: Fe...
Source: Fertility and Sterility - March 28, 2024 Category: Reproduction Medicine Authors: Stanton Charles Honig Tags: Reflections Source Type: research
Technology for Biobanking of Epididymal Spermatozoa from Patient with Obstructive Azoospermia: Case Report about Baby Born after Conventional Freezing Only with a Nonpermeable Cryoprotectant 360 kDa Polyvinylpyrrolidone
Biopreserv Biobank. 2024 Mar 18. doi: 10.1089/bio.2023.0032. Online ahead of print.ABSTRACTThis publication reports, for the first time, the birth of a healthy child after intracytoplasmic sperm injection (ICSI) of motile spermatozoa after conventional ("slow") freezing of epididymal spermatozoa using 5% polyvinylpyrrolidone (PVP) of high molecular weight (360 kDa). Cryopreservation solution with 10% PVP was added to 30 µL of spermatozoa suspension in a 1:1 ratio, with a final PVP concentration of 5%. Then, polycarbonate capillaries for oocyte denudation with a diameter of 170 µm were filled with 60 µL of the resulting ...
Source: Biopreservation and Biobanking - March 18, 2024 Category: Biomedical Science Authors: Maryna Petrushko Taisiia Yurchuk Volodymyr Piniaiev Evgenia Isachenko Gohar Rahimi Peter Mallmann Volodimir Isachenko Source Type: research
Sox9 downregulation in non-obstructive azoospermia by UTF1 and mediator role of POU5F1
Spermatogenesis is the process of producing mature sperm from Spermatogonial stem cells (SSCs) and this process requires a complex cooperation of different types of somatic and germ cells. Undifferentiated spe... (Source: BMC Research Notes)
Source: BMC Research Notes - March 14, 2024 Category: Research Authors: Mehdi Mehdinezhad Roshan, Hossein Azizi, Mohammadreza Ashtari Majelan and Amirreza Niazi Tabar Tags: Research Note Source Type: research
Micromapping testicular sperm extraction: A new technique for microscopic testicular sperm extraction in nonobstructive azoospermia
CONCLUSIONS: MMTSE shows promise as a simple method that comprehensively searches testicular tissue and retrieves sperm using an appropriate method while minimizing patient burden.PMID:38476958 | PMC:PMC10927935 | DOI:10.1002/rmb2.12566 (Source: Reproductive Biology)
Source: Reproductive Biology - March 13, 2024 Category: Reproduction Medicine Authors: Toshihiro Tai Wakaba Miyamoto Yuriko Fukuoka Sena Shibasaki Mizuho Takahashi Noriyuki Okuyama Hiromitsu Hattori Ikue Ishikawa Satoko Nagaura Koki Yoshinaga Masae Koizumi Tomoko Hashimoto Mayumi Toya Jin Kumagai Hideki Igarashi Koichi Kyono Source Type: research
The Utilization of Fine Needle Vasography to Localize Obstruction of the Male Reproductive Tract
To report our experience using fine needle vasography (FNV) to identify a site of obstruction and determine candidacy for reconstructive procedures in patients presenting with suspected obstructive azoospermia or cryptozoospermia. (Source: Urology)
Source: Urology - March 12, 2024 Category: Urology & Nephrology Authors: Abrar Mian, Emily Huang, Nathan R. Starke, Landon Trost, Sevann Helo Source Type: research
The Utilization of Fine-Needle Vasography to Localize Obstruction of the Male Reproductive Tract
To report our experience using fine-needle vasography (FNV) to identify a site of obstruction and determine candidacy for reconstructive procedures in patients presenting with suspected obstructive azoospermia (OA) or cryptozoospermia. (Source: Urology)
Source: Urology - March 12, 2024 Category: Urology & Nephrology Authors: Abrar Mian, Emily Huang, Nathan R. Starke, Landon Trost, Sevann Helo Tags: Infertility Source Type: research
Effects of < em > Perilla frutescens < /em > Var. Acuta in Busulfan-Induced Spermatogenesis Dysfunction Mouse Model
CONCLUSIONS: This study shows that PFA exerts a protective effect against testicular damage by attenuating OS induced by busulfan. Our results suggest that PFA is a potentially relevant drug used to decrease the side effects induced by busulfan on testicular function and sperm during cancer chemotherapy.PMID:38449453 | DOI:10.5534/wjmh.230254 (Source: Cancer Control)
Source: Cancer Control - March 7, 2024 Category: Cancer & Oncology Authors: Hyung Jong Nam Min Jung Park Bo Sun Joo Yean Kyoung Koo SukJin Kim Sang Don Lee Hyun Jun Park Source Type: research
