3D Printed Testicular Cells Offer Hope for Male Infertility
Researchers at the University of British Columbia have developed a technique that lets them 3D print human testicular cells into a hollow tubular structure that mimics the seminiferous tubules found in the testicles. The printed structures are showing encouraging signs that they may be able to produce viable sperm, and the researchers are still working to bring this outcome to fruition. The technology may provide a path to conception for men with fertility issues that are currently difficult or impossible to treat. Infertility can be a huge burden for those that wish to have children. With medical advances, there are no...
Source: Medgadget - March 24, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials Reproductive Medicine ubc Source Type: blogs

Video on the Testicular Rejuvenation Therapy scam for treating azoospermia due to testicular failure
  (Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - December 15, 2020 Category: Reproduction Medicine Source Type: blogs

Testicular Rejuvenation Therapy for Treating Azoospermia because of testicular failure
The ability of IVF specialists to fool their patients continues to boggle my mind. One of the most frustrating unsolved problems in reproductive medicine is that of primary testicular failure . The man hasazoospermia ( zerosperm count) because his testes do not work properly. Spermatogenesis ( sperm production) is impaired, and we do not know why and cannot do anything about this.There have been many experiments with in vitro spermatogenesis, where researchers have tried to create sperm from sperm precursors (spermatogonia and spermatocytes) in the laboratory , but none of these have worked . These patients are understanda...
Source: Dr.Malpani's Blog - December 10, 2020 Category: Reproduction Medicine Source Type: blogs

Testicular Rejuvenation Therapy for Treating Azoospermia
The ability of IVF specialists to fool their patients continues to boggle my mind. One of the most frustrating unsolved problems in reproductive medicine is that of primary testicular failure . The man hasazoospermia ( zerosperm count) because his testes do not work properly. Spermatogenesis ( sperm production) is impaired, and we do not know why and cannot do anything about this.There have been many experiments with in vitro spermatogenesis, where researchers have tried to create sperm from sperm precursors (spermatogonia and spermatocytes) in the laboratory , but none of these have worked . These patients are understanda...
Source: Dr.Malpani's Blog - December 10, 2020 Category: Reproduction Medicine Source Type: blogs

The two major problems with TESA - testicular sperm aspiration
TESAis a simple technique by which doctors can extract sperm from the testes. It ’s partly because it's so simple, that it's often been abused, misused and overused.Thus, many doctors will do TESA unnecessarily , and extract sperm directly from the testes, even in men who have sperm in the semen sample. Not only is this cruel, it also adds needlessly to their expense – without improving the pregnancy rate ! They use all kinds of pretext to justify this TESE ( for example, by claiming that the sperm will be “fresher” or will have lesser DNA fragmentation, but this is rubbish !). The reality is they do this only so t...
Source: Dr.Malpani's Blog - May 19, 2020 Category: Reproduction Medicine Source Type: blogs

IVF video : अशुक्राणुता क्या है ? | What is Azoospermia (in Hindi)
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - January 14, 2020 Category: Reproduction Medicine Source Type: blogs

IVF Video - अशुक्राणुता क्या है ? | What is Azoospermia (in Hindi)
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - December 23, 2019 Category: Reproduction Medicine Source Type: blogs

After failed IVF, can I get pregnant naturally?
Patients do IVF with a lot of hope, because they know this is the one method which maximizes their chances of getting pregnant. They pin all their hopes on the IVF cycle, but when the IVF cycle fails, they are completely heartbroken , and worry about whether they'll ever be able to get pregnant at all.However, do remember that patients do get pregnant even after a failed IVF cycle in their bedroom. The chances of this happening depends on the reason for the infertility.Of course, if you have blocked tubes , or the reason for your infertility is azoospermia, then you're not going to get pregnant on your own.But if your...
Source: Dr.Malpani's Blog - September 22, 2019 Category: Reproduction Medicine Source Type: blogs

A super duper IVF success story !
You hear IVF success stories every now and again but I'm sure ours will be a super duper one!We, Susan and Sunil Silva got married 11 years ago, we didn't have (any biological) kids because my husband had undergone a vasectomy in his previous marriage, after fathering 2 boys. The elder one is with his ex while the younger onechose to be with us- apple of my eye, my son! About 7 years ago we started thinking about having one more child anddecided to give it a try undergoing an IVF ! I started reading and searching for best IVF clinics in the internet and always Dr Malpani's clinic came first in the list and I literally...
Source: Dr.Malpani's Blog - June 23, 2019 Category: Reproduction Medicine Source Type: blogs

MKSAP: 34-year-old man with fatigue, low libido, and infertility
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 34-year-old man is evaluated for a 2-year history of fatigue, low libido, and infertility. His family history is notable for a brother with infertility. His medical history is unremarkable, and he takes no medications. On physical examination, vital signs are normal. His height is 195.6 cm (77 in), and his weight is 86.2 kg (190 lb). Genital examination reveals small, firm testes bilaterally. Laboratory studies reveal a morning serum total testosterone level of 140 ng/dL (4.9 nmol/L) (which was confirmed on re...
Source: Kevin, M.D. - Medical Weblog - December 17, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Endocrinology Source Type: blogs

When the man is shooting blanks - The Ins & Outs of Male infertility
Recent surveys have revealed some alarming facts- 15% of Indian couples in the 31-40 years age group need medical intervention to successfully conceive , as either one or both the partners suffer from fertility issues. Generally, if a couple has unprotected intercourse for a year and are still unable to conceive, they are said to suffer from infertility. The sad truth is that there are number of misconceptions about infertility floating around. The most popular one of course is that it’s always a problem with the woman. This is one myth that has to be debunked. The truth is that in almost 40 percent of all infertility ca...
Source: The Patient's Doctor - January 21, 2015 Category: Obstetricians and Gynecologists Source Type: blogs

A super duper IVF success story !
You hear IVF success stories every now and again but I'm sure ours will be a super duper one!!!We, Susan and Sunil Silva got married 11 years ago, we didn't have (any biological) kids because  my husband had undergone a vasectomy in his previous marriage, after fathering 2 boys. The elder one is with his ex while the younger one chose to be with us- apple of my eye, my son!  About 7 years ago we started thinking about having one more child and and decided to give it a try undergoing an ivf! I started reading and searching for good clinics in the internet and always Dr Malpani's clinic came first in the list and I...
Source: The Patient's Doctor - December 31, 2013 Category: Obstetricians and Gynecologists Source Type: blogs

I am a big fat zero - the azoospermic man
I was doing the final consultation of the day . The couple who walked in were well-dressed and poised. The wife was a CA ; and her husband was an athletic six-footer , who worked as an equity analyst in a leading hedge fund . When I asked them - How can I help you ? “ , much to my surprise, he became extremely emotional. " Doctor, I am a failure. My sperm count is zero and I cannot give my wife a baby ! Even though I have a great job , a big fat bank balance, and get to travel first class all over the world , my life has become meaningless because I am shooting blanks. I don’t even feel like having sex anymore, because...
Source: The Patient's Doctor - December 16, 2013 Category: Obstetricians and Gynecologists Tags: Azoospermia azoospermic man TESA TESE testicular sperm aspiration Testicular sperm extraction zero sperm count Source Type: blogs

What do pus cells in the semen mean ?
Infectious diseases were common in India in the past. Smallpox, for instance, used to result in azoospermia and this infection injured the epididymis, leading to ductal obstruction. Tuberculosis can also affect the epididymis, causing azoospermia. Gonorrhea, chlamydia and syphilis, along with other STDs (sexually transmitted diseases), are also capable of damaging the man's genital system, resulting in irreparable injury. Mumps is another viral disease which could cause inflammation of the testis - particularly when young men are afflicted with it. This could even result in testicular failure if it damages both testes. Th...
Source: The Patient's Doctor - November 11, 2013 Category: Obstetricians and Gynecologists Tags: pyospermia Semen leucocytospermia pus cells Source Type: blogs