Lidocaine effects on neutrophil extracellular trapping and angiogenesis biomarkers in postoperative breast cancer patients with different anesthesia methods: a prospective, randomized trial
Anesthesia techniques and drug selection may influence tumor recurrence and metastasis. Neutrophil extracellular trapping (NETosis), an immunological process, has been linked to an increased susceptibility to ... (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - April 27, 2024 Category: Anesthesiology Authors: Wenjuan Zhang, Jiao Liu, Xiaohui Li, Zhixia Bai, Yan Sun and Xuexin Chen Tags: Research Source Type: research

Lacrimal Neuralgia: A Case Report and Comprehensive Review of the Literature
AbstractPurpose of ReviewLacrimal neuralgia is a rare periorbital neuralgia. To date, only nine cases have been reported in the literature. Herein, we report a case and a comprehensive overview of the entity with a focus on the differential diagnosis of lacrimal neuralgia. Additionally, we propose putative diagnostic criteria for this rare neuralgia based on cases that have been reported.Recent FindingsAmong the ten cases of lacrimal neuralgia reported (including the one in this review), seven out of ten were idiopathic, and the other three were considered secondary. Most patients reported stabbing and shooting pain that w...
Source: Current Pain and Headache Reports - April 27, 2024 Category: Neurology Source Type: research

Alternative sensor montage for Index based EEG monitoring. A systematic review
AbstractThe main objective of this systematic review is to assess the reliability of alternative positions of processed electroencephalogram sensors for depth of anesthesia monitoring and its applicability in clinical practice. A systematic search was conducted in PubMed, Embase, Cochrane Library, Clinical trial.gov in accordance with reporting guidelines of PRISMA statement together with the following sources: Google and Google Scholar. We considered eligible prospective studies, written in the English language. The last search was run on the August 2023. Risk of bias and quality assessment were performed. Data extraction...
Source: Journal of Clinical Monitoring and Computing - April 27, 2024 Category: Information Technology Source Type: research

Direct Oral Anticoagulants: An Update on Monitoring and Antidotes for the Perioperative Physician
AbstractPurpose of ReviewThe purpose of this review is to update the clinician on assessing and reversing the effects of direct oral anticoagulants (DOACs) in the perioperative period.Recent FindingsTraditional coagulation tests such as the PT and aPTT are not recommended to determine clinically significant effects of DOACs. Instead, the dilute thrombin time and chromogenic anti-Xa level can be used to guide the need for reversal of direct thrombin inhibitors and Factor Xa inhibitors respectively. Additionally, point of care assays such as viscoelastic testing and urine screening are under investigation. Current reversal s...
Source: Current Anesthesiology Reports - April 27, 2024 Category: Anesthesiology Source Type: research

Transabdominal Motor Evoked Potential Neuromonitoring of Lumbosacral Spine Surgery
Transcranial Motor Evoked Potentials (TcMEPs) can improve intraoperative detection of femoral plexus and nerve root injury during lumbosacral spine surgery. However, even under ideal conditions, TcMEPs are not completely free of false-positive alerts due to the immobilizing effect of general anesthetics, especially in the proximal musculature. The application of transcutaneous stimulation to activate ventral nerve roots directly at the level of the conus medularis (bypassing the brain and spinal cord) has emerged as a method to potentially monitor the motor component of the femoral plexus and lumbosacral nerves free from t...
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: David W. Allison, Amit Verma, Paul J. Holman, Meng Huang, Todd W. Trask, Sean M. Barber, Anthony R. Cockrell, Matthew R. Weber, Dalton W. Brooks, Leo Delgado, William J. Steele, Jonathan N. Sellin, Loyola V. Gressot, Bradley Lambert, Brandy B. Ma, Amir H. Tags: Clinical Study Source Type: research

The use of Pulmonary Artery Catheter and of Echocardiography in the cardiac surgery setting: a nationwide Italian survey.
Wide variations exist in the use of pulmonary artery catheter (PAC) and echocardiography in the field of cardiac surgery. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 27, 2024 Category: Anesthesiology Authors: Filippo Sanfilippo, Alberto Noto, Valentina Ajello, Blanca Martinez Lopez de Arroyabe, Tommaso Aloisio, Pietro Bertini, Michele Mondino, Simona Silvetti, Antonio Putaggio, Carlotta Continella, Marco Ranucci, Fabio Sangalli, Sabino Scolletta, Gianluca Pate Source Type: research

Renal implications of pneumoperitoneum in laparoscopic surgery: mechanisms, risk factors, and preventive strategies
Korean J Anesthesiol. 2024 Apr 26. doi: 10.4097/kja.24011. Online ahead of print.ABSTRACTPneumoperitoneum, which is established for laparoscopic surgery, has systemic implications on the renal system and may contribute to acute kidney injury or postoperative renal dysfunction. Specifically, when the pressure exceeds 10 mmHg, pneumoperitoneum decreases renal blood flow, leading to renal dysfunction and temporary oliguria. The renal effects of pneumoperitoneum stem from both the direct effects of increased intra-abdominal pressure and indirect factors such as carbon dioxide absorption, neuroendocrine influences, and tissue d...
Source: Korean Journal of Anesthesiology - April 26, 2024 Category: Anesthesiology Authors: Gianluca Villa Marco Fiorentino Eleonora Cappellini Sergio Lassola Silvia De Rosa Source Type: research

Effective bolus dose of remimazolam for i-gel < sup > ® < /sup > insertion in nonparalyzed patients: a dose-finding study
CONCLUSION: Based on the ED95 of remimazolam bolus dose determined in our study, we recommend using 0.182 mg·kg-1 of remimazolam in combination with remifentanil TCI at a Ce of 3.0 ng·mL-1 for successful i-gel insertion without NMBAs in adult patients. This regimen seems effective with a low risk of hemodynamic instability during anesthesia induction.STUDY REGISTRATION: ClinicalTrials.gov ( NCT05298228 ); first submitted 6 March 2022.PMID:38671251 | DOI:10.1007/s12630-024-02762-w (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 26, 2024 Category: Anesthesiology Authors: Eunah Cho Yun Ho Roh Jisu Moon Yangjin Kim Seokyung Shin Source Type: research

Cubital tunnel release with Wide Awake Local Anaesthesia No Tourniquet (WALANT) technique in an outpatient setting is safe and effective
This study aims to evaluate clinical outcomes after ulnar nerve release under WALANT 27 patients with ulnar nerve release for cubital tunnel syndrome were included. The primary outcome was the presence of (remaining) symptoms after ulnar nerve release. Data was extracted from medical records. 13 out of 27 patients had (mild) remaining symptoms after ulnar nerve release, and 1 complication (superficial wound infection) was seen. Ulnar nerve release under WALANT is safe and effective in patients with primary ulnar nerve entrapment that have failed conservative therapy.PMID:38669651 | DOI:10.52628/90.1.12681 (Source: Acta Orthopaedica Belgica)
Source: Acta Orthopaedica Belgica - April 26, 2024 Category: Orthopaedics Authors: C Bruggink I Koenraadt-VAN Oost A Beumer B The Source Type: research

Efficacy of local infiltration analgesia on recovery after total hip arthroplasty using direct anterior approach under spinal anaesthesia: a randomized, double-blind, placebo-controlled trial
Acta Orthop Belg. 2024 Mar;90(1):11-15. doi: 10.52628/90.1.12345.ABSTRACTThe utilization of local infiltration analgesia (LIA) is a common practice in total hip arthroplasty (THA) procedures to mitigate postoperative pain and diminish the necessity for opioids. However, contemporary literature reports conflicting results. Our working hypothesis was that LIA renders better postoperative VAS-scores and reduces the need for oral analgetics. We performed a randomized, double-blind, placebo-controlled trial aimed at examining the effectiveness of LIA in THA. A total of 90 patients were included for statistical analysis. Our pri...
Source: Acta Orthopaedica Belgica - April 26, 2024 Category: Orthopaedics Authors: S Biesemans B Schuermans E Voets H Feyen Source Type: research

Renal implications of pneumoperitoneum in laparoscopic surgery: mechanisms, risk factors, and preventive strategies
Korean J Anesthesiol. 2024 Apr 26. doi: 10.4097/kja.24011. Online ahead of print.ABSTRACTPneumoperitoneum, which is established for laparoscopic surgery, has systemic implications on the renal system and may contribute to acute kidney injury or postoperative renal dysfunction. Specifically, when the pressure exceeds 10 mmHg, pneumoperitoneum decreases renal blood flow, leading to renal dysfunction and temporary oliguria. The renal effects of pneumoperitoneum stem from both the direct effects of increased intra-abdominal pressure and indirect factors such as carbon dioxide absorption, neuroendocrine influences, and tissue d...
Source: Korean Journal of Anesthesiology - April 26, 2024 Category: Anesthesiology Authors: Gianluca Villa Marco Fiorentino Eleonora Cappellini Sergio Lassola Silvia De Rosa Source Type: research

Effective bolus dose of remimazolam for i-gel < sup > ® < /sup > insertion in nonparalyzed patients: a dose-finding study
CONCLUSION: Based on the ED95 of remimazolam bolus dose determined in our study, we recommend using 0.182 mg·kg-1 of remimazolam in combination with remifentanil TCI at a Ce of 3.0 ng·mL-1 for successful i-gel insertion without NMBAs in adult patients. This regimen seems effective with a low risk of hemodynamic instability during anesthesia induction.STUDY REGISTRATION: ClinicalTrials.gov ( NCT05298228 ); first submitted 6 March 2022.PMID:38671251 | DOI:10.1007/s12630-024-02762-w (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 26, 2024 Category: Anesthesiology Authors: Eunah Cho Yun Ho Roh Jisu Moon Yangjin Kim Seokyung Shin Source Type: research

Cubital tunnel release with Wide Awake Local Anaesthesia No Tourniquet (WALANT) technique in an outpatient setting is safe and effective
This study aims to evaluate clinical outcomes after ulnar nerve release under WALANT 27 patients with ulnar nerve release for cubital tunnel syndrome were included. The primary outcome was the presence of (remaining) symptoms after ulnar nerve release. Data was extracted from medical records. 13 out of 27 patients had (mild) remaining symptoms after ulnar nerve release, and 1 complication (superficial wound infection) was seen. Ulnar nerve release under WALANT is safe and effective in patients with primary ulnar nerve entrapment that have failed conservative therapy.PMID:38669651 | DOI:10.52628/90.1.12681 (Source: Acta Orthopaedica Belgica)
Source: Acta Orthopaedica Belgica - April 26, 2024 Category: Orthopaedics Authors: C Bruggink I Koenraadt-VAN Oost A Beumer B The Source Type: research

Efficacy of local infiltration analgesia on recovery after total hip arthroplasty using direct anterior approach under spinal anaesthesia: a randomized, double-blind, placebo-controlled trial
Acta Orthop Belg. 2024 Mar;90(1):11-15. doi: 10.52628/90.1.12345.ABSTRACTThe utilization of local infiltration analgesia (LIA) is a common practice in total hip arthroplasty (THA) procedures to mitigate postoperative pain and diminish the necessity for opioids. However, contemporary literature reports conflicting results. Our working hypothesis was that LIA renders better postoperative VAS-scores and reduces the need for oral analgetics. We performed a randomized, double-blind, placebo-controlled trial aimed at examining the effectiveness of LIA in THA. A total of 90 patients were included for statistical analysis. Our pri...
Source: Acta Orthopaedica Belgica - April 26, 2024 Category: Orthopaedics Authors: S Biesemans B Schuermans E Voets H Feyen Source Type: research

Renal implications of pneumoperitoneum in laparoscopic surgery: mechanisms, risk factors, and preventive strategies
Korean J Anesthesiol. 2024 Apr 26. doi: 10.4097/kja.24011. Online ahead of print.ABSTRACTPneumoperitoneum, which is established for laparoscopic surgery, has systemic implications on the renal system and may contribute to acute kidney injury or postoperative renal dysfunction. Specifically, when the pressure exceeds 10 mmHg, pneumoperitoneum decreases renal blood flow, leading to renal dysfunction and temporary oliguria. The renal effects of pneumoperitoneum stem from both the direct effects of increased intra-abdominal pressure and indirect factors such as carbon dioxide absorption, neuroendocrine influences, and tissue d...
Source: Korean Journal of Anesthesiology - April 26, 2024 Category: Anesthesiology Authors: Gianluca Villa Marco Fiorentino Eleonora Cappellini Sergio Lassola Silvia De Rosa Source Type: research