Study: Work in adulthood seen to significantly delay memory decline after age 60, supporting the Cognitive Reserve theory
Conclusions: Women who worked for pay in early adulthood and midlife experienced slower rates of later-life memory decline, regardless of marital and parenthood status, suggesting participation in the paid labor force may protect against later-life memory decline.
The Study in Context:
Study: High Cognitive Reserve (CR) seen to significantly lower dementia risk even in the presence of high Alzheimer’s Disease (AD) neuropathology
Build Your Cognitive Reserve: An Interview with Dr. Yaakov Stern
Systematic review finds ten lifestyle factors that clearly impact the probability of developing Alzheimer’s disease (AD)
How l...
Source: SharpBrains - November 10, 2020 Category: Neuroscience Authors: Alvaro Fernandez Tags: Brain/ Mental Health cognitive cognitive-domains cognitive-reserve cognitive-stimulation memory-decline memory-loss paid work social-engagement working Source Type: blogs
Fight Aging! Newsletter, November 9th 2020
In this study, young adult mice were submitted to endurance exercise training and the function, differentiation, and metabolic characteristics of satellite cells were investigated in vivo and in vitro.
We found that injured muscles from endurance-exercised mice display improved regenerative capacity, demonstrated through higher densities of newly formed myofibres compared with controls (evidenced by an increase in embryonic myosin heavy chain expression), as well as lower inflammation (evidenced by quantifying CD68-marked macrophages), and reduced fibrosis. Enhanced myogenic function was accompanied by an increased ...
Source: Fight Aging! - November 8, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
6 Foods That Protect Against Memory Loss (M)
The foods all contain an anti-inflammatory that combats age-related changes in the brain.
→ Support PsyBlog for just $5 per month. Enables access to articles marked (M) and removes ads.
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Accept Yourself: How to feel a profound sense of warmth and self-compassion
The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic
Spark: 17 Steps That Will Boost Your Motivation For Anything
Activate: How To Find Joy Again By Changing What You Do (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 4, 2020 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Memory Nutrition subscribers-only Source Type: blogs
RyR2 as a Target to Prevent Alzheimer's Symptoms in a Mouse Model of the Condition
Mouse models of Alzheimer's disease are quite artificial: mice, and indeed most mammals, do not naturally exhibit the relevant mechanisms underlying Alzheimer's disease, such as aggregation of amyloid-β. The details of the model become important in determining whether or not discoveries and interventions are relevant in anything other than the model. Thus one shouldn't become too excited by any small adjustment to cellular metabolism that appears to have profound effects on the progression of the condition in these models. Maybe it will be relevant to the human condition, but the odds are not good, looking at the history ...
Source: Fight Aging! - November 2, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, October 5th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 4, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Learning is Damaged Before Memory in the Progression to Clinical Alzheimer's
Researchers searching for better ways to assess the early progression towards clinical Alzheimer's disease have established what looks like a decent way to measure loss of learning capability, a decline that occurs well before loss of memory function. This sort of approach compares poorly with a hypothetical blood biomarker or other non-invasive, low-cost assay, but while there are a few promising inroads towards the development of such a test, none have yet emerged into clinical practice.
As amyloid-β (Aβ) accumulates in a person's brain during the long preclinical stage of Alzheimer's disease, deficits in lear...
Source: Fight Aging! - September 30, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fornix infarction
This patient presented with amnesia. MRI revealed fornix infarction. The fornix plays an important role in the human memory by connecting the hippocampus with other structures involved with memory, including the anterior thalami, septal nuclei, and mammillary bodies. Amnesia, resulting from lesions involving the fornix, has been attributed to the damage of this vital link.Famous Radiology Blog http://www.sumerdoc.blogspot.com
TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com (Source: Sumer's Radiology Site)
Source: Sumer's Radiology Site - September 17, 2020 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Elon Musk ’s Neuralink Shares More About Its Implantable Brain Stimulator
Neuralink, one of Elon Musk’s newest ventures, was founded in 2016 but little has been known about the startup other than that it would somehow actualize Musk’s vision of a revolutionary implantable brain device. During a webcast last week, Musk and his team unveiled a bit more about what the company has been up to, including a live demo involving a trio of pigs.
The Neuralink implant, known as the “Link,” is essentially a miniaturized version of a deep brain stimulator. It’s a coin-sized device with a bundle of tiny wires, each five times thinner than a strand of human hair, protrudin...
Source: Medgadget - August 31, 2020 Category: Medical Devices Authors: Scott Jung Tags: Neurology Neurosurgery Source Type: blogs
How to Create an ICU for Mind and Body
The importance of healing is often overlooked in modern society, yet some of the most effective strategies are simply achieved and inexpensive or free. Best of all, they work. In fact, they may seem, at first glance, to be so easy they couldn’t possibly help. During grief, after trauma, or for general well-being, these practices can help you create your own intensive care unit for your mind and body.
Recognize the need for time apart from your normal routine. Investing time in yourself is important for everyday wellness and for giving yourself a chance to heal from specific emotional or physical wounds. Rare is the pers...
Source: World of Psychology - August 19, 2020 Category: Psychiatry & Psychology Authors: Jan McDaniel Tags: Grief and Loss Self-Help Stress grieving Journaling Self Care Source Type: blogs
On Stress, Yoga Meditation, and The Evolution Revolution
In the Tale of Two Cities, Charles Dickens wrote:
“It was the best of times, it was the worst of times. It was the age of wisdom, it was the age of foolishness…. It was the season of light, it was the season of darkness. It was the spring of hope, it was the winter of despair”
Yes, the period of which Dickens wrote is a lot like the present day.
We are living through extraordinary times in a complicated world. In my 74 ½ years, I’ve never seen anything like it — from the virus to political strife to protests, stress is rampant.
Stress may impact negatively virtually every system of our body, from the immune sy...
Source: SharpBrains - August 14, 2020 Category: Neuroscience Authors: Dr. Dharma Singh Khalsa at Alzheimer's Research & Prevention Foundation Tags: Cognitive Neuroscience Health & Wellness anxiety chronic-stress depression immune system insomnia Kirtan-Kriya lower cognitive ability mbsr meditation mental health Mindfulness-Based-Stress-Reduction telomere Transcendental Med Source Type: blogs
How to Get Into Star Trek
This article idea was suggested by a Conscious Growth Club member. After a little reflection, I thought, why not?
I’ve seen every episode of every non-animated Star Trek series, including the original 1960s classic, The Next Generation, Deep Space Nine, Voyager, Enterprise, Discovery, and the new Picard series. I’ve seen many episodes multiple times. I’ve seen all of the movies. I’ve been to a Star Trek Convention in Las Vegas. So I’m pretty well versed in Star Trek lore.
I met William Shatner (aka Captain Kirk) very briefly when I was in my 20s because we had the same lawyer for a while...
Source: Steve Pavlina's Personal Development Blog - August 13, 2020 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Lifestyle Values Source Type: blogs
How Exercise Affects Your Mood?
"It is exercise alone that supports the spirits, and keeps the mind in vigour."- Marcus Tullius Cicero
What is wellbeing?
Wellbeing is defined as ‘a positive physical, social and mental state’.
In this article, we are focusing on mental wellbeing. Mental wellbeing does not have a single universal definition, but it does encompass several factors such as:
The sense of feeling good about ourselves and being able to function well individually and/or even in relationshipsThe ability to deal with the ups and downs of life, such as coping with various challenges and making the most of such opportunitiesThe feelin...
Source: PickTheBrain | Motivation and Self Improvement - August 5, 2020 Category: Consumer Health News Authors: Trishna Patnaik Tags: featured health and fitness motivation philosophy self-improvement exercise improve your mood pickthebrain Source Type: blogs
Fight Aging! Newsletter, August 3rd 2020
In this study, we examined the effects of oxytocin on the Aβ-induced impairment of synaptic plasticity in mice.
To investigate the effect of oxytocin on synaptic plasticity, we prepared acute hippocampal slices for extracellular recording and assessed long-term potentiation (LTP) with perfusion of the Aβ active fragment (Aβ25-35) in the absence and presence of oxytocin. We found that oxytocin reversed the impairment of LTP induced by Aβ25-35 perfusion in the mouse hippocampus. These effects were blocked by pretreatment with the selective oxytocin receptor antagonist L-368,899. Furthermore, the treatment with the...
Source: Fight Aging! - August 2, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Evidence for Oxytocin to Reverse Impairment of Synaptic Plasticity by Amyloid- β
In this study, we examined the effects of oxytocin on the Aβ-induced impairment of synaptic plasticity in mice.
To investigate the effect of oxytocin on synaptic plasticity, we prepared acute hippocampal slices for extracellular recording and assessed long-term potentiation (LTP) with perfusion of the Aβ active fragment (Aβ25-35) in the absence and presence of oxytocin. We found that oxytocin reversed the impairment of LTP induced by Aβ25-35 perfusion in the mouse hippocampus. These effects were blocked by pretreatment with the selective oxytocin receptor antagonist L-368,899. Furthermore, the treatment with the...
Source: Fight Aging! - July 28, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Psychology Around the Net: July 25, 2020
This week’s Psychology Around the Net takes a look at what causes revenge bedtime procrastination (a phenomenon I’m way too familiar with), the psychological toll of rude emails, why “I did by best” is a sorry (pun intended) excuse, and more.
Stay well, friends!
Don’t Fall Into the Trap of ‘Revenge Bedtime Procrastination’: Ever find yourself staying up late at night, even if you spent the entire day ticking item after item off your to-do list, even if there isn’t really anything else you need to do, and even if all your body wants to do is sleep? It’s called revenge b...
Source: World of Psychology - July 25, 2020 Category: Psychiatry & Psychology Authors: Alicia Sparks Tags: Psychology Around the Net alzheimer's Body Dysmorphic Disorder Boundaries Codependency Eating Disorders Oxytocin Postpartum revenge bedtime procrastination Sleep Source Type: blogs
