More on Fibrinogen and Blood-Brain Barrier Leakage in the Aging Brain
The blood-brain barrier lines the blood vessels of the brain, and only very selectively allows passage of molecules to and from the brain. As is the case for all tissue structures, it fails with age. Molecular damage and cell dysfunction causes it to become leaky, and as a consequence all sorts of cells and proteins make their way into the brain to cause damage. One of these is fibrinogen, which appears toxic to brain cells. Here, researchers elaborate on previous findings, suggesting that this is an immune activation problem, and may be a significant cause of neurodegenerative conditions that exhibit significant loss of s...
Source: Fight Aging! - February 13, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Valentine's Day: Celebrating When a Loved One Has Dementia
Photo credit Denise Johnson
...For my parents, flowers and cards were always essential, especially on Valentine’s Day and their wedding anniversary. Sadly, after a failed brain surgery left my father with dementia, it was obvious that Dad could no longer actively participate in these celebrations. As my mom aged, she began experiencing some memory loss as well. I knew that, if he could make the decision, Dad would want to give Mom flowers and a card to show her how loved she was. I also knew Mom would want to do the same in return.
Read the full article on Agingcare about how we celebrated Valentine's Day with dem...
Source: Minding Our Elders - February 12, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
A Sense Of Self Can Survive The Memory Loss Of Dementia, Argue Review Authors
By Christian Jarrett
In the past when scholars have reflected on the psychological impact of dementia they have frequently referred to the loss of the “self” in dramatic and devastating terms, using language such as the “unbecoming of the self” or the “disintegration” of the self. In a new review released as a preprint at PsyArXiv, an international team of psychologists led by Muireann Irish at the University of Sydney challenge this bleak picture which they attribute to the common, but mistaken, assumption “that without memory, there can be no self” (as encapsulated by the l...
Source: BPS RESEARCH DIGEST - February 5, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Memory The self Source Type: blogs
“The Self Is Not Entirely Lost In Dementia,” Argues New Review
By Christian Jarrett
In the past when scholars have reflected on the psychological impact of dementia they have frequently referred to the loss of the “self” in dramatic and devastating terms, using language such as the “unbecoming of the self” or the “disintegration” of the self. In a new review released as a preprint at PsyArXiv, an international team of psychologists led by Muireann Irish at the University of Sydney challenge this bleak picture which they attribute to the common, but mistaken, assumption “that without memory, there can be no self” (as encapsulated by the l...
Source: BPS RESEARCH DIGEST - February 5, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Memory The self Source Type: blogs
Fight Aging! Newsletter, January 28th 2019
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging.
Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia
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Source: Fight Aging! - January 27, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Towards Reliable, Low-Cost Tests for the Earliest Stages of Alzheimer's Disease
The research community has moved quite determinedly these past few years towards practical, low-cost tests for early Alzheimer's disease. Even with the limited means available to patients today, an early warning might be used to delay the aggregation of amyloid-β that takes place in the initial stages of the condition, before the appearance of cognitive impairment. Lifestyle changes such as weight loss and improved fitness, antiviral therapies, and control of chronic inflammation should all make some difference, given what is known of the mechanisms of Alzheimer's disease. Looking ahead, better options may soon be availab...
Source: Fight Aging! - January 25, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Alzheimer ’s Memory Loss Dramatically Reversed
Mouse study reverses memory loss in mice with Alzheimer's.
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Source: PsyBlog | Psychology Blog - January 24, 2019 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs
This Drink Reduces Memory Loss Risk 70%
The common drink may help to delay dementia.
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Accept Yourself: How to feel a profound sense of warmth and self-compassion
The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic
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Activate: How To Find Joy Again By Changing What You Do (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 23, 2019 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs
New Research Raises Concerns About the Dangers of Marijuana Use
Whatever your personal position on the subject of marijuana legalization, whether for medical or recreational use, a growing body of research reveals concerns over the potential harms caused by cannabis.
The concerns are more than academic. With increasing public support (varying by demographic cohorts) for legalized marijuana, and 10 states legalizing recreational marijuana and 33 states where medical marijuana use is legal, the cannabis movement is just gaining steam.
A new Pew Research Center report shows that 6 in 10 Americans (62 percent) say marijuana should be legal. Millennials support legalized marijuana more tha...
Source: World of Psychology - January 20, 2019 Category: Psychiatry & Psychology Authors: Suzanne Kane Tags: Memory and Perception Mental Health and Wellness Research Substance Abuse Cannabis Drug Use Marijuana side effects Source Type: blogs
The Diet That Cuts The Risk Of Memory Loss
The supplement that may slow brain aging.
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The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic
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Activate: How To Find Joy Again By Changing What You Do (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 18, 2019 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Memory Source Type: blogs
Why Making a Resolution to Get Sober Matters
Making the Resolution to Get Sober
The new year is a time to reflect and plan for the brand new year ahead. Think about this: Have your relationship with friends and family been stressed over the holiday season? Have family and other loved ones distanced themselves due to your addictions? Or maybe, you feel this way toward a family member or friend of yours? It might be time to make the resolution to get sober.
Approximately 40 percent of Americans make resolutions, viewing the new year as a fresh start. It can be an excellent opportunity to make a step in the right direction and conquer your dependency issues. Taking that...
Source: Cliffside Malibu - January 17, 2019 Category: Addiction Authors: Jaclyn Uloth Tags: Addiction Alcoholism Drug Rehab Information Drug Treatment Substance Abuse alcohol treatment alcohol treatment center alcohol treatment facility New Year resolutions sober sobriety Source Type: blogs
Alirocumab – a PCSK9 inhibitor
Alirocumab – a PCSK9 inhibitor
Alirocumab is a human monoclonal antibody to proprotein convertase subtilisin–kexin type 9 (PCSK9). It is used to treat high cholesterol which is not controlled by diet and statin therapy. Those with statin intolerance will also benefit from this drug. It may be noted that several patients treated with currently available oral lipid lowering agents do not reach target low density lipoprotein cholesterol (LDL-C) levels recommended by clinical guidelines. The cardiovascular risk of these patients remain significantly high. Earlier, these patients had only one option – LDL apheres...
Source: Cardiophile MD - January 13, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs
The Best Supplement For Memory Loss
The supplement halves the rate of brain shrinkage.
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NEW: Accept Yourself: How to feel a profound sense of warmth and self-compassion
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Activate: How To Find Joy Again By Changing What You Do (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 11, 2019 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs
Intimate partner violence and traumatic brain injury: An “invisible” public health epidemic
While studying brain injuries in the mid-1990s, I began volunteering in a domestic violence shelter. I noticed that the abuse and problems many women reported were consistent with possibly experiencing concussions. Women reported many acts of violence that could cause trauma to the brain, as well as many post-concussive symptoms. Shockingly, my search for literature on this topic yielded zero results.
When I decided to focus my graduate work on this topic, I was even more shocked by what I learned from women who had experienced intimate partner violence (IPV). Of the 99 women I interviewed, 75% reported at least one trauma...
Source: Harvard Health Blog - December 13, 2018 Category: Consumer Health News Authors: Eve Valera, PhD Tags: Concussions Neurological conditions Women's Health Source Type: blogs
Visiting a Person Living with Alzheimer's
Many people have told me how difficult they find it to visit friends and family who have Alzheimer ’s and dementia.By Marilyn RaichleAlzheimer's Reading Room“We have nothing to talk about. I don’t know what to say.”“It’s so sad – she is everything she never wanted to be.”“She would hate this so much. This was her worst nightmare.”So the pattern begins...Subscribe to the Alzheimer's Reading RoomEmail:Visiting makes you sad or uncomfortable,so you don ’t visit.Not visiting makes you feel guilty, so you put off visiting again.“She won’t remember it anyway,” you rationalize.Dementia Patients are Peo...
Source: Alzheimer's Reading Room, The - December 12, 2018 Category: Neurology Tags: alzheimer s alzheimers care alzheimers caregiving Alzheimers Dementia Alzheimers Disease alzheimers information dementia care health memory memory loss Source Type: blogs
