The Lipid Invasion Model of Alzheimer's Disease
Researchers here discuss a model of Alzheimer's disease that is centered around consequences of the age-related disruption of the blood-brain barrier. This barrier of specialized cells lines blood vessels in the central nervous system, and acts to control the passage of cells and molecules to and from the brain. Unfortunately, it becomes leaky with age, failing just like every other system and structure in the body. The researchers propose an interesting hypothesis, but it stands as one of many new ways to look at Alzheimer's disease. A great deal of theorizing has been provoked by the ongoing failure to make progress in t...
Source: Fight Aging! - April 14, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Regulatory Shifting Baseline Syndrome: Vaccines, Generational Amnesia, and the Shifting Perception of Risk in Public Law Regimes
Robin Kundis Craig (USC), Regulatory Shifting Baseline Syndrome: Vaccines, Generational Amnesia, and the Shifting Perception of Risk in Public Law Regimes, 21 Yale J. Health Pol ’y Ethics (forthcoming, summer 2022): Vaccination mandates have been controversial since long before COVID-19, but... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - March 30, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
2 Portions Of This Food Halves Risk Of Memory Loss
Any variety may well have the beneficial effect as they all contain an antioxidant called ergothioneine. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 28, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs
The Diet That Cuts The Risk Of Memory Loss
The supplement that may slow brain aging. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 24, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Memory Source Type: blogs
The Bare Minimum Exercise To Avoid Memory Loss (M)
Difficulty remembering autobiographical events is one of the first signs of Alzheimer's, the most common form of dementia. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 15, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Memory subscribers-only Source Type: blogs
Fight Aging! Newsletter, March 14th 2022
This study tests the feasibility of chronically elevating skeletal muscle NAD+ in mice and investigates the putative effects on mitochondrial respiratory capacity, insulin sensitivity, and gene expression. The metabolic effects of NR and PT treatment were modest. We conclude that the chronic elevation of skeletal muscle NAD+ by the intravenous injection of NR is possible but does not affect muscle respiratory capacity or insulin sensitivity in either sedentary or physically active mice. Our data have implications for NAD+ precursor supplementation regimens.
Muscle Strengthening Activities in Later Life Correlate ...
Source: Fight Aging! - March 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Clearance of Senescent Cells is a Promising Approach to the Treatment of Alzheimer's Disease
Today's open access review discusses the growing burden of cellular senescence with age in the context of brain tissue and neurodegenerative disease. Cells become senescent constantly throughout life, largely the result of ordinary somatic cells hitting the Hayflick limit on replication, but also, and increasingly with age, due to a stressful, damaging, inflammatory environment. Senescent cells serve a useful purpose when present for the short term, in the context of wound healing or cancer suppression for example, by rousing the immune system into action and changing the behavior of nearby cells. But the signaling of sene...
Source: Fight Aging! - March 10, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Memory Loss: This Supplement Slows Brain Shrinkage By 50%
The supplement halves the rate of brain shrinkage. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 6, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs
Fight Aging! Newsletter, March 7th 2022
This study estimates that prescreening with a 500 blood test could reduce by half both the cost and the time it takes to enroll patients in clinical trials that use PET scans. Screening with blood tests alone could be completed in less than six months and cut costs by tenfold or more, the study finds. Known as Precivity AD, the commercial version of the test is marketed by C2N Diagnostics. The current study shows that the blood test remains highly accurate, even when performed in different labs following different protocols, and in different cohorts across three continents.
xCT Knockout Modestly Extends Life in M...
Source: Fight Aging! - March 6, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Brain Foods That Reduce Your Dementia Risk (M)
A version of the Mediterranean diet reduces memory loss and slows down brain shrinkage. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - February 28, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Dementia subscribers-only Source Type: blogs
Cellular Reprogramming in the Popular Press
One of the potential side effects of there now being a very sizable amount of funding devoted to realizing therapies based on in vivo partial reprogramming of cells is an increase in the quality of popular press articles about the treatment of aging as a medical condition. We can hope that journalists become a touch more careful and considered when it comes to a field in which billions in funding are now flowing towards research and development. The bar is of course quite low in the matter of journalism and the science of aging, but improvement is always welcome.
The latest exploration into longevity research is '...
Source: Fight Aging! - February 28, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
This Drink Reduces Risk Of Memory Loss 47%
A familiar beverage that may help protect the brain from aging. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - February 26, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Memory Source Type: blogs
This Sleep Pattern Accelerates Memory Loss – Possible Link to Alzheimer’s (M)
Sleep pattern lowered levels of an antioxidant that helps fight cellular damage, such as that caused by Alzheimer's. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - February 20, 2022 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Memory Sleep subscribers-only Source Type: blogs
The Mineral That Reverses Memory Loss
Supplementation of this natural mineral can reverse memory loss and cognitive deficits. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - February 14, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Memory Source Type: blogs
Will Microbes Finally Force Modernization of the American Health Care System?
Mike Magee MD
Science has a way of punishing humans for their arrogance.
In 1996, Dr. Michael Osterholm found himself rather lonely and isolated in medical research circles. This was the adrenaline-infused decade of blockbuster pharmaceuticals focused squarely on chronic debilitating diseases of aging.
And yet, there was Osterholm, in Congressional testimony delivering this message: “I am here to bring you the sobering and unfortunate news that our ability to detect and monitor infectious disease threats to health in this country is in serious jeopardy…For 12 of the States or territories, there is no one w...
Source: The Health Care Blog - February 14, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Public Health Healthcare system infectious diseases microbes Mike Magee Source Type: blogs
