PSY6 Differences in All-Cause Health Care Costs of Alopecia Areata in the United States by Patient Subgroups: A Latent Class Approach
This study identified subgroups of patients with AA in the US with distinct profiles and their corresponding healthcare costs. (Source: Value in Health)
Source: Value in Health - June 1, 2021 Category: International Medicine & Public Health Authors: N. Done, M. Ray, K. Gandhi, E. Swallow, W. Gao, V. Sikirica, C. Carley, A. Mostaghimi Source Type: research
Prediction of the Risk of Alopecia Areata Progressing to Alopecia Totalis and Alopecia Universalis: Biomarker Development with Bioinformatics Analysis and Machine Learning
Conclusions: In the present study, we conducted high accuracy models for predicting the risk of AA patients progressing to AT or AU, which may be important in facilitating personalized therapeutic strategies and clinical management for different AA patients.Dermatology (Source: Dermatology)
Source: Dermatology - May 18, 2021 Category: Dermatology Source Type: research
Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options
AbstractPatients suffering from alopecia areata (AA) can lose hair in focal regions, the complete scalp, including eyelashes and eyebrows, or even the entire body. The exact pathology is not yet known, but the most described theory is a collapse of the immune privilege system, which can be found in some specific regions of the body. Different treatment options, local and systemic, are available, but none of them have been proven to be effective in the long term as well for every treatment there should be considered for the possible side effects. In many cases, treated or non-treated, relapse often occurs. The prognosis is ...
Source: Clinical and Experimental Medicine - January 1, 2021 Category: Research Source Type: research
Discoid Lupus Erythematosus in a Patient With Alopecia Totalis
Publication date: Available online 28 December 2020Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): M. Yamamoto, T. Yamamoto (Source: Actas Dermo-Sifiliograficas)
Source: Actas Dermo-Sifiliograficas - December 29, 2020 Category: Dermatology Source Type: research
18763 Validation of case identification for alopecia areata using International Classification of Diseases (ICD) coding
The aim of this study was to assess the validity of the International Classification of Diseases (ICD) 9 and 10 codes for the identification of alopecia areata (AA) in a large clinical database. A multicenter retrospective review was performed at Columbia University Irving Medical Center and Brigham and Women ’s Hospital to determine whether patients with an ICD-9 code (704.01, Alopecia Areata) or ICD-10 codes (L63.0, Alopecia Totalis; L63.1, Alopecia Universalis; L63.2, Ophiasis; L63.8, Other Alopecia Areata; L63.9, Alopecia Areata, Unspecified) met diagnostic criteria for AA. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 28, 2020 Category: Dermatology Authors: Sara J. Li, Jonathan Lavian, Eunice Lee, Lindsey Bordone, Fernanda Caroline da Graca Polubriaginof, Angela Christiano, Arash Mostaghimi Source Type: research
Validation of case identification for alopecia areata using international classification of diseases coding
Conclusions: Patients whose medical records contain an AA-associated ICD code have a high probability of having the condition. (Source: International Journal of Trichology)
Source: International Journal of Trichology - November 3, 2020 Category: Dermatology Source Type: research
Demographic and Clinical Features of 1,641 Patients with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis: A Single-Center Retrospective Study
Conclusion: AA is affecting approximately 2% of the general population without any sex, race, or age group predilection. In this study, we found a lower prevalence of AA in the pediatric age group in comparison with adults. This finding may support the hypothesis of the increasing prevalence of AA over time. The higher ratio of AA regarding this study may support that the frequency of AA and subtypes varies between regions.Skin Appendage Disord (Source: Skin Appendage Disorders)
Source: Skin Appendage Disorders - October 28, 2020 Category: Dermatology Source Type: research
Discoid lupus erythematosus in a patient with alopecia totalis.
PMID: 32926840 [PubMed - as supplied by publisher] (Source: Actas Dermo-Sifiliograficas)
Source: Actas Dermo-Sifiliograficas - September 10, 2020 Category: Dermatology Authors: Yamamoto M, Yamamoto T Tags: Actas Dermosifiliogr Source Type: research
A Large Cross-Sectional Survey Study of the Prevalence of Alopecia Areata in the United States.
Conclusion: This study suggests that the current AA prevalence in the US is similar to the upper estimates from the 1970s at approximately 0.21% (700,000 persons) with the current prevalence of "moderate to severe" disease at approximately 0.09% (300,000 persons). Given this prevalence and the substantial impact of AA on quality of life, the burden of AA within the US is considerable.
PMID: 32280257 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - April 15, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research
Cyclosporine With and Without Systemic Corticosteroids in Treatment of Alopecia Areata: A Systematic Review
ConclusionCyclosporine in combination with oral systemic corticosteroids is more effective than in monotherapy for severe alopecia areata. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 7, 2020 Category: Dermatology Source Type: research
Bi-Allelic UQCRFS1 Variants Are Associated with Mitochondrial Complex III Deficiency, Cardiomyopathy, and Alopecia Totalis
Isolated complex III (CIII) deficiencies are among the least frequently diagnosed mitochondrial disorders. Clinical symptoms range from isolated myopathy to severe multi-systemic disorders with early death and disability. To date, we know of pathogenic variants in genes encoding five out of 10 subunits and five out of 13 assembly factors of CIII. Here we describe rare bi-allelic variants in the gene of a catalytic subunit of CIII, UQCRFS1, which encodes the Rieske iron-sulfur protein, in two unrelated individuals. (Source: The American Journal of Human Genetics)
Source: The American Journal of Human Genetics - December 25, 2019 Category: Genetics & Stem Cells Authors: Mirjana Gusic, Gudrun Schottmann, Ren é G. Feichtinger, Chen Du, Caroline Scholz, Matias Wagner, Johannes A. Mayr, Chae-Young Lee, Vicente A. Yépez, Norbert Lorenz, Susanne Morales-Gonzalez, Daan M. Panneman, Agnès Rötig, Richard J.T. Rodenburg, Saski Tags: Report Source Type: research
Assessment of Treatment Efficacy of Diphenylcyclopropenone (DPCP) for Alopecia Areata.
Conclusions There was a significant relation between the severity of alopecia and treatment outcome. (p=0.038) Patients with alopecia areata had significantly better response when compared to alopecia totalis and universalis. There was no statistically significant relation with other parameters such as disease duration, age, gender, atopy history, age of onset, and histopathological features.
PMID: 31655499 [PubMed - as supplied by publisher] (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - October 29, 2019 Category: General Medicine Tags: Turk J Med Sci Source Type: research
