Alopecia Areata: Case report and review of pathophysiology and treatment with Jak inhibitors
J Autoimmun. 2022 Nov 2;133:102926. doi: 10.1016/j.jaut.2022.102926. Online ahead of print.ABSTRACTAlopecia Areata (AA) is a T-cell mediated autoimmune attack on hair follicles resulting in rapidly developing areas of hair loss involving the scalp and beard that can progress to total scalp hair loss (alopecia totalis) and loss of eyebrows, eyelashes, and total body hair (alopecia universalis). Affected patients have high rates of psychological disorders and decreased quality of life. There are no FDA approved treatments, and the available treatments have a high failure rate. JAK inhibitors are remarkably effective in many ...
Source: Journal of Autoimmunity - November 6, 2022 Category: Allergy & Immunology Authors: Isabelle Paggioli Jeremy Moss Source Type: research
Alopecia Areata: Case report and review of pathophysiology and treatment with Jak inhibitors
J Autoimmun. 2022 Nov 2;133:102926. doi: 10.1016/j.jaut.2022.102926. Online ahead of print.ABSTRACTAlopecia Areata (AA) is a T-cell mediated autoimmune attack on hair follicles resulting in rapidly developing areas of hair loss involving the scalp and beard that can progress to total scalp hair loss (alopecia totalis) and loss of eyebrows, eyelashes, and total body hair (alopecia universalis). Affected patients have high rates of psychological disorders and decreased quality of life. There are no FDA approved treatments, and the available treatments have a high failure rate. JAK inhibitors are remarkably effective in many ...
Source: Journal of Autoimmunity - November 6, 2022 Category: Allergy & Immunology Authors: Isabelle Paggioli Jeremy Moss Source Type: research
Alopecia Areata: Case report and review of pathophysiology and treatment with Jak inhibitors
J Autoimmun. 2022 Nov 2;133:102926. doi: 10.1016/j.jaut.2022.102926. Online ahead of print.ABSTRACTAlopecia Areata (AA) is a T-cell mediated autoimmune attack on hair follicles resulting in rapidly developing areas of hair loss involving the scalp and beard that can progress to total scalp hair loss (alopecia totalis) and loss of eyebrows, eyelashes, and total body hair (alopecia universalis). Affected patients have high rates of psychological disorders and decreased quality of life. There are no FDA approved treatments, and the available treatments have a high failure rate. JAK inhibitors are remarkably effective in many ...
Source: Journal of Autoimmunity - November 6, 2022 Category: Allergy & Immunology Authors: Isabelle Paggioli Jeremy Moss Source Type: research
Rituximab-Induced Alopecia Universalis in a Patient With Bullous Pemphigoid
J Drugs Dermatol. 2022 Aug 1;21(8):894-895. doi: 10.36849/JDD.6690.ABSTRACTAlopecia areata is a CD8+ T-lymphocyte driven autoimmune disorder leading to reversible hair loss. While most commonly presenting as isolated well-demarcated non-cicatricial alopecic patches on the scalp, subtypes of alopecia areata include alopecia totalis with loss of all scalp hair and alopecia universalis with complete loss of all body hair. Although primarily an idiopathic condition, several triggers, including medications, have been reported in the literature. To the best of our knowledge, we present the first reported case of rituximab, a chi...
Source: Journal of Drugs in Dermatology - August 10, 2022 Category: Dermatology Authors: Tudor Puiu Danielle Reimer Olayemi Sokumbi Source Type: research
