Identifying a Stem Cell Population in the Adult Thymus
Researchers here report on the characterization of a stem cell population in the adult thymus that gives rise to the thymic epithelial cells that allow the thymus to host the development of T cells of the adaptive immune system. This is of interest because the thymus atrophies with age, losing active thymic epithelial tissue. The supply of new T cells provided to the immune system diminishes greatly as a consequence, and this is a major contributing factor in the age-related decline of immune function. It is the case that cell therapy approaches are one of the potential ways in which an aged thymus might be regenerated, an...
Source: Fight Aging! - September 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Answer to Case 725
 Answer toParasite Case of the Week 725: Swimmer ' s itchAs noted by Florida Fan, this is " typical swimmer ’s itch, also known by other names depending on the activity of the patient like ' clam digger ’s itch ' or ' duck itch ' . " (Also called Pelican itch in Australia) " All are caused by [zoonotic] cercariae in most freshwater bodies of water frequented by ducks and/or water birds. The cercariae penetrate the skin and cause a cercarial dermatitis. This summer is so hot even in the Northern most states that a quick plunge into the lake is certainly very appealing. We may expect to see more cases like this one....
Source: Creepy Dreadful Wonderful Parasites - September 3, 2023 Category: Parasitology Source Type: blogs

Ragweed allergy peaks during college football season
Not only is it kickoff time for college football season, but it’s also prime time for fall allergies. For the 50 million Americans who suffer from ragweed allergy, the late summer and early fall signal the onset of runny noses, sneezing, congestion, cough, itchy watery eyes, and in more severe cases, sinus infections and asthma Read more… Ragweed allergy peaks during college football season originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 2, 2023 Category: General Medicine Authors: Tags: Conditions Allergies & Immunology Source Type: blogs

Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan. « Back to Top Trials of Xenotransplantation of Pig Organs into Humans Continue https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/ Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants i...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Ming Lei Departs Division for Research Capacity Building
It’s with mixed emotions that I share that Ming Lei left our Division for Research Capacity Building (DRCB) earlier this month to become senior associate vice president for research and graduate education at West Virginia University (WVU) Health Sciences. Ming also joined the faculty in WVU’s School of Medicine as vice dean for research and a professor in the department of microbiology, immunology, and cell biology. Ming has been part of the NIH community since 2008, serving in key positions at the National Cancer Institute before joining NIGMS in 2018. During his tenure in DRCB, Ming led numerous initiatives to...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - August 24, 2023 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Director’s Messages NIGMS Staff News Source Type: blogs

Trials of Xenotransplantation of Pig Organs into Humans Continue
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants into terminally ill volunteers and brain dead individuals who donated their bodies to science. To learn by doing is really the only practical way by which the presently unknown problems are discovered. This trial of kidney transplantation ran for longer than prior efforts, and is a step on the path to producing a ready supply of non-human organs for transplantation, a technology that will compete with efforts to grow new organs on demands. Su...
Source: Fight Aging! - August 24, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

MedEssist is Helping to Transform Pharmacies into Pharmacy Health Clinics
The healthcare system in many countries is stretched thin. To help relieve the pressure, governments are starting to allow pharmacists to treat a growing number of minor ailments. MedEssist’s technology platform is helping pharmacies transform into health clinics. Healthcare IT Today got a brief demonstration of the MedEssist platform from Joella Almeida, CEO and Co-Founder at the Collision Conference. We also asked her about the expanding role of pharmacists in healthcare. Pharmacies Are Already in the Community “We are focused on helping independent pharmacies,” explained Almeida. “There’s one on every bloc...
Source: EMR and HIPAA - August 16, 2023 Category: Information Technology Authors: Colin Hung Tags: Ambulatory Communication and Patient Experience Health IT Company Healthcare IT Collision 2023 Collision Conference Joella Almeida MedEssist minor ailments Pharmacies Pharmacists pharmacy health clinics Source Type: blogs

Best Blood Pressure Monitors For Apple Health
In conclusion, Apple Health and compatible blood pressure monitors represent the synergy between technology and healthcare, redefining health management’s future. This amalgamation fosters a detailed and proactive perspective toward personal health, emphasizing the need for maintaining awareness and making educated health choices. As technological advancements persist, our capacity to control and comprehend our health will likewise expand, heralding a new age of customized healthcare. Reference Central-acting agents – Drugs.com. (n.d.). Retrieved July 24, 2023, from https://www.drugs.com/mca/central-ac...
Source: The EMT Spot - August 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Monitors Source Type: blogs

Survivors of Nuclear Weapon Use in Early Life Exhibit Accelerated Immune Aging in Late Life
It probably strains the meaning of the term to call the aftermath of the use of nuclear weapons at the end of the Second World War a natural experiment, but nonetheless there has been considerable study of survivors from those events and their health relative to control populations in other parts of Japan. Irradiation is known to produce what is effectively accelerated aging in the context of cancer treatment, producing an increased burden of senescent cells that then ensure the later course of health for survivors is worse than would otherwise be the case, absent both cancer and treatment. In the case of exposure to radia...
Source: Fight Aging! - August 14, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't ...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

In the Long Run, Even Baseline Humans Will Live for a Very, Very Long Time
It is at present somewhat out of style to point out that, yes, obviously, it will be possible in the future to ensure that humans live for a very, very long time. That will be true for even baseline humans lacking all of the various genetic modifications one might propose a future scientific community to be capable of, modifications to introduce the numerous distinct forms of resilience to the mechanisms of mammalian aging exhibited by naked mole-rats, whales, elephants, bats and so forth. Control over aging is a subset of control over molecules and their positions. To be as reductionist as possible, degenerative aging is ...
Source: Fight Aging! - August 9, 2023 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

These Three Things Can Bring EHRs to the Next Level
The following is a guest article by Dr. Mark Pratt, Chief Medical Officer at Altera Digital Health The patient quietly sits while her physician delves into the data stored in her electronic health record, combing through different screens for specific information. It takes longer than both expect, precious minutes that diminish the available time for an actual conversation about the patient’s health status and the physician’s recommendations. This familiar scene exemplifies the unnecessary burdens traditional EHRs have placed on providers, patients, and the overall healthcare system. As a former ER physician and curren...
Source: EMR and HIPAA - August 4, 2023 Category: Information Technology Authors: Guest Author Tags: Ambulatory C-Suite Leadership Clinical EMR-EHR Health IT Company Healthcare IT Hospital - Health System LTPAC Altera Digital Health Clinical Usability Dr. Mark Pratt FHIR Flexible EHR Workflows Interoperability Physician Burnou Source Type: blogs

Investigating the Secrets of Cancer-Causing Viruses
Credit: Courtesy of Dr. Mandy Muller. While she was in graduate school, Mandy Muller, Ph.D., became intrigued with viruses that are oncogenic, meaning they can cause cancer. At the time, she was researching human papillomaviruses (HPVs), which can lead to cervical and throat cancer, among other types. Now, as an assistant professor of microbiology at the University of Massachusetts (UMass) Amherst, Dr. Muller studies Kaposi sarcoma-associated herpesvirus (KSHV), which causes the rare AIDS-associated cancer Kaposi sarcoma. A Continental Change Dr. Muller has come a long way, both geographically and professionally, s...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 1, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Infectious Diseases Microbes Profiles RNA Viruses Source Type: blogs

How to protect your epithelial barriers and improve your health [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join Kara Wada, an adult and pediatric allergy, immunology, and lifestyle medicine physician, as we discuss the epithelial barrier hypothesis. What is the epithelial barrier hypothesis? What are some of the diseases that have been linked to epithelial barrier dysfunction? What are some of Read more… How to protect your epithelial barriers and improve your health [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 29, 2023 Category: General Medicine Authors: Tags: Podcast Allergies & Immunology Source Type: blogs