Usage, residue, and human health risk of antibiotics in Chinese aquaculture: A review.
Abstract
Aquaculture is a booming industry in the world and China is the largest producer and exporter of aquatic products. To prevent and treat diseases occurred in aquaculture, antibiotics are widely applied. However, the information of antibiotics used in Chinese aquaculture is still limited. Based on peer-reviewed papers, documents, reports, and even farmer surveys, this review summarized antibiotics used in Chinese aquaculture. In 2014, more than 47.4 million tonnes of farmed aquatic products were produced in mainland China. The outputs in the east and south parts of China can reach as much as 600 tim...
Source: Environmental Pollution - January 24, 2017 Category: Environmental Health Authors: Liu X, Steele JC, Meng XZ Tags: Environ Pollut Source Type: research
Effects of Menthol Supplementation in Feedlot Cattle Diets on the Fecal Prevalence of Antimicrobial-Resistant < i > Escherichia coli < /i >
by C. C. Aperce, R. Amachawadi, C. L. Van Bibber-Krueger, T. G. Nagaraja, H. M. Scott, J. Vinasco-Torre, J. S. Drouillard
The pool of antimicrobial resistance determinants in the environment and in the gut flora of cattle is a serious public health concern. In addition to being a source of human exposure, these bacteria can transfer antibiotic resistance determinants to pathogenic bacteria and endanger the future of antimicrobial therapy. The occurrence of antimicrobial resistance genes on mobile genetic elements, such as plasmids, facilitates spread of resistance. Recent work has shownin vitro anti-plasmid activity of me...
Source: PLoS One - December 27, 2016 Category: Biomedical Science Authors: C. C. Aperce Source Type: research
Antimicrobial susceptibility, virulence gene and pulsed-field gel electrophoresis profiles of Salmonella enterica serovar Typhimurium recovered from retail raw chickens, China
Publication date: February 2017 Source:Food Control, Volume 72, Part A Author(s): Keting Li, Shuyao Ye, Walid Q. Alali, Yin Wang, Xin Wang, Xiaodong Xia, Baowei Yang A total of 138 Salmonella enterica serovar Typhimurium isolates recovered from retail raw chickens in seven provinces of China from 2007 to 2012 were characterized for antimicrobial susceptibility, genotype and presence of virulence genes. Resistance was most frequently detected to sulfisoxazole (90.6%), tetracycline (73.2%), nalidixic acid (65.9%), ceftiofur (59.4%), ampicillin (54.3%) and kanamycin (34.8%). Resistance to cefoxitin (6.5%), amikacin (...
Source: Food Control - July 31, 2016 Category: Food Science Source Type: research
Quantitative determination of sulfisoxazole and its three N-acetylated metabolites using HPLC –MS/MS, and the saturable pharmacokinetics of sulfisoxazole in mice
Publication date: 10 September 2016 Source:Journal of Pharmaceutical and Biomedical Analysis, Volume 129 Author(s): Kyungsoo Oh, Moonchang Baek, Wonku Kang Sulfisoxazole (SFX) is still used in combination with trimethoprim in cattle despite adverse drug reactions (e.g., urolithiasis). Recently, SFX is known to be a promising repositioned drug candidate for pulmonary hypertension and cancer. We developed a simultaneous determination method of SFX and its N-acetylated metabolites (N1-acetyl SFX, N1AS; N4-acetyl SFX, N4AS; diacetyl SFX, DAS) using HPLC–MS/MS for the first time, and examined the pharmacokinetics of...
Source: Journal of Pharmaceutical and Biomedical Analysis - July 24, 2016 Category: Drugs & Pharmacology Source Type: research
Prevalence and Antimicrobial Resistance Patterns of Diarrheagenic Escherichia coli in Shanghai, China
Conclusion: Our findings suggest that active surveillance programs combining both phenotypic and genetic data would help identify disease outbreaks and strengthen antibiotic management. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - July 21, 2016 Category: Infectious Diseases Tags: Original Studies Source Type: research
Simultaneous determination of N1-acetyl sulfisoxazole and its metabolites, and relative bioavailability compare to sulfisoxazole in rats
Publication date: 10 September 2016 Source:Journal of Pharmaceutical and Biomedical Analysis, Volume 129 Author(s): Eunyoung Kim, Wonku Kang N 1-acetyl sulfisoxazole (N1AS), a dihydropteroate synthase inhibitor is known to be biotransformed primarily to sulfisoxazole, partly to N 4-acetyl sulfisoxazole (N4AS), and likely also to diacetyl sulfisoxazole (DAS) and other compounds. Although its clinical use has been limited due to urolithiasis, some countries still use the drug in combination with trimethoprim in cattle. A liquid chromatographic method using ultraviolet detection was developed for the simultaneous det...
Source: Journal of Pharmaceutical and Biomedical Analysis - July 14, 2016 Category: Drugs & Pharmacology Source Type: research
Prevalence and antibiotic resistance of bacterial pathogens isolated from childhood diarrhea in Beijing, China (2010–2014)
Conclusion
Constant antibiotic surveillance is warranted because the bacteria were highly resistant to various antimicrobials. Our study contributes to the strengthening of the existing surveillance system and provides aid for effective prevention and control strategies for childhood diarrhea. (Source: Gut Pathogens)
Source: Gut Pathogens - June 12, 2016 Category: Microbiology Source Type: research
Prevalence and characterization of Salmonella enterica serovar in retail meats in market place in Uighur, Xinjiang, China
Publication date: June 2016 Source:Food Control, Volume 64 Author(s): Mingyuan Yin, Baowei Yang, Yun Wu, Lu Wang, Haotian Wu, Tao Zhang, Gulinazi Tuohetaribayi Ninety nine Salmonella isolates recovered from 1414 retail meats were characterized by serotyping, antimicrobial susceptibility, pulsed-field gel electrophoresis (PFGE), presence of amino acid mutation in quinolone resistance determination region (QRDR) of DNA gyrase subunit A (GyrA) and topoisomerase IV subunit C (ParC), and of qnrA, qnrB, qnrS, aac(6′)-Ib, qepA, and oqxAB. Among 1414 retail meat samples, 96 (6.8%) including 49 (9.0%) chickens, ...
Source: Food Control - January 11, 2016 Category: Food Science Source Type: research
Drug use and antimicrobial resistance among Escherichia coli and Enterococcus spp. isolates from chicken and turkey flocks slaughtered in Quebec, Canada.
The objectives were to estimate prevalence of drug use at hatchery and on farm and to identify antimicrobial resistance (AMR) in cecal Escherichia coli and Enterococcus spp. isolates and factors associated with AMR. Eighty-two chicken flocks and 59 turkey flocks were sampled. At the hatchery, the most used antimicrobial was ceftiofur in chickens (76% of flocks) and spectinomycin in turkeys (42% of flocks). Virginiamycin was the antimicrobial most frequently added to the feed in both chicken and turkey flocks. At least 1 E. coli isolate resistant to third-generation cephalosporins was present in all chicken flocks and in a ...
Source: Canadian Journal of Veterinary Research - January 1, 2016 Category: Veterinary Research Authors: Boulianne M, Arsenault J, Daignault D, Archambault M, Letellier A, Dutil L Tags: Can J Vet Res Source Type: research
Electro-catalytic degradation of sulfisoxazole by using graphene anode
This study implies that graphene is a promising potential electrode material for long-term application to electro-catalytic degradation of organic pollutants. Graphical abstract (Source: Journal of Environmental Sciences)
Source: Journal of Environmental Sciences - December 4, 2015 Category: Environmental Health Source Type: research
Non-typhoidal Salmonella serotypes, antimicrobial resistance and co-infection with parasites among patients with diarrhea and other gastrointestinal complaints in Addis Ababa, Ethiopia
Conclusions:
The study demonstrated significant association of Salmonella infection with consumption of raw vegetables. There was no significant association of Salmonella infection with co-occurring parasites. The study also showed the dominance of S. Typhimurium and S. Virchow in primary health care units. Overall, prevalence of MDR was low compared to previous studies. Although their proportion was low, S. Kentucky and S. Concord demonstrated wider spectrum of MDR. Continuous monitoring of circulating serotypes, antimicrobial resistance profile and characterization on molecular resistance determinants is essential for pr...
Source: BMC Infectious Diseases - November 4, 2015 Category: Infectious Diseases Authors: Tadesse EgualeWondwossen GebreyesDaniel AsratHaile AlemayehuJohn GunnEphrem Engidawork Source Type: research
Antimicrobial susceptibility, virulence gene profiles and molecular subtypes of Salmonella Newport isolated from humans and other sources.
Abstract
Salmonella Newport (S. Newport) is a major serotype associated with human salmonellosis. A total of 79 S. Newport recovered from humans and other sources in China were characterized for antimicrobial susceptibility, virulence gene profiles and molecular subtypes using pulsed field gel electrophoresis (PFGE). Approximately 63.3% of the isolates were susceptible to all of 16 antimicrobials tested. Nearly one third of the isolates (31.6%) were resistant to sulfisoxazole, 20.3% to tetracycline and 13.9% to nalidixic acid. Twelve isolates (15.2%) were resistant to three or more antimicrobials. Among 10...
Source: Infection, Genetics and Evolution - October 3, 2015 Category: Genetics & Stem Cells Authors: Kuang D, Xu X, Meng J, Yang X, Jin H, Shi W, Pan H, Liao M, Su X, Shi X, Zhang J Tags: Infect Genet Evol Source Type: research
Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae
Conclusions
This is the first description of mobilizable plasmids conferring trimethoprim resistance in A. pleuropneumoniae and, to our knowledge, the first report of dfrA14 in any member of the Pasteurellaceae. The identification of dfrA14 conferring trimethoprim resistance in A. pleuropneumoniae isolates will facilitate PCR screens for resistance to this important antimicrobial. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - July 13, 2015 Category: Microbiology Authors: Bosse, J. T., Li, Y., Walker, S., Atherton, T., Fernandez Crespo, R., Williamson, S. M., Rogers, J., Chaudhuri, R. R., Weinert, L. A., Oshota, O., Holden, M. T. G., Maskell, D. J., Tucker, A. W., Wren, B. W., Rycroft, A. N., Langford, P. R., on behalf of Tags: Original research Source Type: research
Evaluation of bilirubin displacement effect by acetaminophen in vitro
Conclusion
Acetaminophen is an accelerator of the reaction in the glucose oxidase peroxidase method and does not displace bilirubin from human serum albumin. (Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - June 15, 2015 Category: Biochemistry Authors: Sugino, M., Okada, H., Kusaka, T., Itoh, S. Tags: Original Articles Source Type: research
Ferrate promoted oxidative cleavage of sulfonamides: Kinetics and product formation under acidic conditions
Publication date: 1 November 2015 Source:Chemical Engineering Journal, Volume 279 Author(s): Chansik Kim , Venkata R. Panditi , Piero R. Gardinali , Rajender S. Varma , Hyunook Kim , Virender K. Sharma Sulfonamide-based antibiotics are often detected in surface water and secondary wastewater effluent and pose an eminent threat for the development of antibiotic resistance bacteria and genes in aquatic environment. This paper presents the kinetics and stoichiometry of the oxidation of sulfonamides (sulfaguanidine, sulfisoxazole, sulfamethizole, sulfamethoxazole (SMX), sulfamethazine, and sulfadimethoxine) by ferrat...
Source: Chemical Engineering Journal - June 9, 2015 Category: Chemistry Source Type: research
