Sex hormone-binding globulin has no effect on salivary testosterone
(Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Keevil, B. G., Fiers, T., Kaufman, J.-M., Macdowall, W., Clifton, S., Lee, D., Wu, F. Tags: Letters Source Type: research
Serum and urinary endocan levels for bladder cancer diagnosis
(Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Hu, Z.-D. Tags: Letters Source Type: research
Glucose sampling: importance of citrate
(Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Carta, M., Montagnana, M., Cascio, C. L., Bonetti, G., on behalf of the Italian joint SIBioC-SIPMeL study group on diabetes mellitus Tags: Letters Source Type: research
2016 Endocrine Society guidelines update for the diagnosis of primary aldosteronism: are the proposed aldosterone-to-renin ratio cut-off values relevant in the era of fully automated immunoassays?
(Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Denimal, D., Duvillard, L. Tags: Letters Source Type: research
Practical clinical chemistry: core concepts
(Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Evans, E. Tags: Book Review Source Type: research
Using machine learning to predict laboratory test results
(Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Wilkes, E. E. Tags: Journal Watch Source Type: research
Liraglutide and cardiovascular outcomes in type 2 diabetes
(Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Jones, B. Tags: Journal Watch Source Type: research
Multiple myeloma and multiple plasmacytomas associated with free gamma heavy chain, free kappa light chain and IgGk paraproteins: an unusual triple gammopathy
We present a patient whose clonally evolved disease from monoclonal gammopathy of undetermined significance to multiple myeloma demonstrated the presence of an unusual combination of monoclonal immunoproteins. Capillary electrophoresis demonstrated the presence of three paraproteins in the gamma region (-region), two of which were additional to the IgGk paraprotein which migrated in the slow -region at initial diagnosis. Subsequent isotypic identification of the new paraproteins was not possible by immunotyping and initial immunofixation studies failed to definitively characterize the monoclonal proteins. After reduction w...
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Deighan, W. I., OKane, M. J., McNicholl, F. P., Keren, D. F. Tags: Case Report Source Type: research
The effect of multiple analysers on the biochemical diagnosis of myocardial infarction using a contemporary troponin-I assay
Conclusions
We demonstrate that there are significant differences between the performances of analysers which can impact the biochemical criteria for the diagnosis of MI. We also show that the RCV varies according to baseline cTn-I values and that reporting a single RCV across the analytical range of cTn-I may not be appropriate. (Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Pethick, J., Patel, P., Davies, T., Thompson, J., Nallagonda, M., Beech, A., Collinson, P., Lee, V., Gupta, P. Tags: Short Reports Source Type: research
EDTA interference in electrochemiluminescence ACTH assay
Conclusion
We recommend that inadequately filled EDTA specimens should be rejected when using Cobas ACTH assay. (Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Toprak, B., Yalcin, H., Arı, E., Colak, A. Tags: Short Reports Source Type: research
Different percentages of false-positive results obtained using five methods for the calculation of reference change values based on simulated normal and ln-normal distributions of data
Conclusions
The optimal choice of method to calculate reference change value limits requires knowledge of the distribution of data (normal or ln-normal) and, if possible, knowledge of the homeostatic set point. (Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Lund, F., Petersen, P. H., Fraser, C. G., Söletormos, G. Tags: Research Articles Source Type: research
Analytical performance specifications for changes in assay bias ({Delta}bias) for data with logarithmic distributions as assessed by effects on reference change values
Conclusion
The traditional and simple to apply model used to generate analytical performance specifications for reference change value, based on the use of coefficients of variation and assuming Gaussian distributions for both CVI and CVA, is generally useful. (Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Petersen, P. H., Lund, F., Fraser, C. G., Söletormos, G. Tags: Research Articles Source Type: research
Clinical relevance of trace element measurement in patients on initiation of parenteral nutrition
Conclusion
In patients on short-term parenteral nutrition, measurement of C-reactive protein is essential when interpreting zinc and selenium but not copper results. Routine measurement of trace elements prior to commencing parenteral nutrition has to be considered on an individual basis in patients with inflammation. (Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Salota, R., Omar, S., Sherwood, R. A., Raja, K., Vincent, R. P. Tags: Research Articles Source Type: research
A survey of Lab Tests Online-UK users: a key resource for patients to empower and help them understand their laboratory test results
Conclusions
This survey provides good evidence that the Lab Tests Online-UK website is a useful resource for patients and health-care professionals alike. It comes at a poignant time as the release of results direct to patients starts with access to their medical records. The Lab Tests Online-UK website has a key role in enabling patients to understand their lab test results, and therefore empowering them to take an interest and engage in their own healthcare. (Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Leyland, R., Freedman, D. B. Tags: Research Articles Source Type: research
Cytokine profiles in overweight and obese subjects and normal weight individuals matched for age and gender
Conclusion
Despite significant differences in several cytokines between the groups, only monocyte chemoattractant protein-1appeared to be independently related to a measure of adiposity in this population sample from Iran. (Source: Annals of Clinical Biochemistry)
Source: Annals of Clinical Biochemistry - October 11, 2016 Category: Biochemistry Authors: Azizian, M., Mahdipour, E., Mirhafez, S. R., Shoeibi, S., Nematy, M., Esmaily, H., Ferns, G. A., Ghayour-Mobarhan, M. Tags: Research Articles Source Type: research
