Distinct Microbial Communities in Dilated Cardiomyopathy Explanted Hearts Are Associated With Different Myocardial Rejection Outcomes

ConclusionsThis initial study investigating on infectious agents and inflammation in the IDCM explanted hearts showed that the association between M. pneumoniae and hepatitis B core was associated with a worse outcome after HT, represented by MR and PMR, suggesting that different IDCM microbial communities may be contributing to post-transplant myocardial rejection.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research

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CONCLUSION: It is concluded that co-culture of MSCs with Molt-4 cells could be involved in the changing the methylation status of hTERT gene promoter, cell cycle and hTERT protein expression; it could potentially beneficial for further investigations regarding the cell transplantation and cell-based therapy.PMID:35040412 | DOI:10.2174/1566524022666220118103136
Source: Current Molecular Medicine - Category: Molecular Biology Authors: Source Type: research
CONCLUSIONS: This initial study investigating on infectious agents and inflammation in the IDCM explanted hearts showed that the association between M. pneumoniae and hepatitis B core was associated with a worse outcome after HT, represented by MR and PMR, suggesting that different IDCM microbial communities may be contributing to post-transplant myocardial rejection.PMID:34912727 | PMC:PMC8668412 | DOI:10.3389/fcimb.2021.732276
Source: Herpes - Category: Infectious Diseases Authors: Source Type: research
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