Acute Arthritis/Osteomyelitis in Children

OSTEOMYELITIS IN CHILDREN: Osteomyelitis (OM) is defined as an infection of the bone marrow and adjacent osseous structures with potential surrounding soft tissue extent. It can occur at any age, generally in children 1 –16 years old. In children, it is predominantly caused by hematogenous spread of infection, typically bacterial. Generally, the metaphysis is involved. Transphyseal spread to the epiphysis and joint is rare but can occur in children younger than 18 months, or in older children with closed growth p lates, due to a different blood perfusion to the epiphysis. The first imaging modality of choice is conventional radiography (CR), but CR has limited sensitivity in early stages. Osseous destruction is evident only 10–14 days after the initial infection. In low-grade osteomyelitis, nonspecific sof t tissue swelling and subtle bone resorption or a lytic lesion at the metaphysis may be seen, as in more advanced stages, lytic bone destruction, and periosteal formation are seen. Magnetic resonance imaging (MRI) is the preferred modality for early detection of lesions. Brodie’s abscess is a subt ype of osteomyelitis typically seen in children, with intraosseous abscess formation (Figure 1). Another specific subtype of OM is chronic recurrent multifocal osteomyelitis (CRMO), which is characterized by multiple sterile inflammatory bone lesions with a relapsing and remitting course. Whole-body MRI is increasingly being used for evaluation. OM has a variable...
Source: Journal of the Belgian Society of Radiology - Category: Radiology Source Type: research

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Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
We present two cases of AOT, the first case concerns a 23-year-old patient with an AOT located in the maxilla and the second case involves a 37-year-old patient presenting an AOT with mandibular localization.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
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Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Condition:   Juvenile Idiopathic Arthritis Hip Intervention:   Radiation: pelvic radiograph Sponsor:   University Tunis El Manar Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Fabry Disease Interventions:   Drug: Venglustat (GZ402671);   Drug: Placebo Sponsor:   Genzyme, a Sanofi Company Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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