For 25 years Luke needed jabs to stop bleeding. Now he's been liberated by a breakthrough therapy 
When Luke Pembroke was diagnosed with the bleeding disorder haemophilia at 11 months old, doctors offered his mother Debra a glimmer of hope - one day there might be a cure. (Source: the Mail online | Health)
Source: the Mail online | Health - August 2, 2022 Category: Consumer Health News Source Type: news

Photographer Rankin Captures The Humanity In People With Hemophilia
People with hemophilia can bleed spontaneously and uncontrollably following an operation or injury. But thanks to innovations in treatment, they can lead long and healthy lives. Photographer Rankin tells their inspirational stories through his exhibit, Portraits of Progress. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 27, 2022 Category: Pharmaceuticals Authors: Lipi Roy, MD, MPH, Contributor Tags: Healthcare /healthcare Innovation /innovation Arts /arts business pharma & Source Type: news

Sustained Normal Factor IX Levels Seen With Gene Therapy in Hemophilia B
(MedPage Today) -- Durable factor IX levels in the normal range were observed with a single dose of an experimental gene therapy, eliminating the need for factor IX prophylaxis, in men with severe or moderately severe hemophilia B, according to... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - July 26, 2022 Category: Hematology Source Type: news

Impact of depression on patients with hemophilia: a retrospective case-control research - Jim énez-Cebrián AM, Palomo-López P, Becerro-de-Bengoa Vallejo R, Losa-Iglesias ME, Navarro-Flores E, San-Antolín M, Calvo-Lobo C, López-López D.
BACKGROUND: Hemophilia is an inherited recessive hemorrhagic disorder of the X-linked type, suffered by the male sex. Adults with hemophilia are coping with numerous diagnostics, associated comorbidities, pain, and difficult gait by arthropathy in ankles a... (Source: SafetyLit)
Source: SafetyLit - July 25, 2022 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Gene Therapies for Hemophilia Treatment Will Face Strong Market...
Solid market position of Hemlibra and strong prescriber interest in RNAi and TFPI treatment options, combined with patient concerns regarding gene therapies, are likely to create obstacles to market...(PRWeb July 25, 2022)Read the full story at https://www.prweb.com/releases/2022/7/prweb18802371.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - July 25, 2022 Category: Pharmaceuticals Source Type: news

Gene therapy reduced risk of excessive bleeding for people with hemophilia B, early trial data suggests
A one-time novel gene therapy can reduce the risk of excessive bleeding in people with the bleeding disorder hemophilia B, who typically would need repeat therapies to reduce their risk, according to results from a Phase 1-2 trial. (Source: CNN.com - Health)
Source: CNN.com - Health - July 23, 2022 Category: Consumer Health News Source Type: news

No More Injections After One-Off Gene Therapy in Hemophilia B No More Injections After One-Off Gene Therapy in Hemophilia B
The novel gene therapy normalized and stabilized factor IX levels in 9 of 10 patients with moderate to severe hemophilia B, removing the need for regular injections.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 22, 2022 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Gene Therapy Makes Inroads Against a Form of Hemophilia
FRIDAY, July 22, 2022 -- People with hemophilia B could find their bleeding risk dramatically reduced with just one injection of an experimental gene therapy, a new study reports. Hemophilia B is a rare and inherited genetic disorder in which people... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 22, 2022 Category: General Medicine Source Type: news

Gene Therapy Makes Inroads Against a Form of Hemophilia
Title: Gene Therapy Makes Inroads Against a Form of HemophiliaCategory: Health NewsCreated: 7/22/2022 12:00:00 AMLast Editorial Review: 7/22/2022 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - July 22, 2022 Category: Anesthesiology Source Type: news

Haemophilia can be cured through 'miracle' therapy
University College London researchers say a one-off gene therapy blood transfusion could stop people with haemophilia having to take weekly injections to manage the rare condition. (Source: the Mail online | Health)
Source: the Mail online | Health - July 21, 2022 Category: Consumer Health News Source Type: news

Gene therapy trial markedly cuts bleeding risk in haemophilia B patients
Single injection of FLT180 removes need for people to inject weekly with clotting factors, study findsA new gene therapy has dramatically cut the risk of bleeding in people with the rare condition haemophilia B, experts have said.Researchersfound that a single injection of the gene therapy, called FLT180a, removed the need for people to inject themselves weekly with clotting factors.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 21, 2022 Category: Science Authors: PA Media Tags: Genetics Health Biology Science Research UK news Source Type: news

[Ad hoc announcement pursuant to Art. 53 LR] Roche achieves good results in the first six months of 2022
Basel, 21 July 2022Group sales up 5%1 at constant exchange rates (CER) and 5% in Swiss francsPharmaceuticals Divisionsales increase 3%; continued strong demand for new medicines to treat severe diseases; as expected, the impact of biosimilars slows down furtherDiagnostics Divisionsales grow 11%; ongoing strong base business; demand for COVID-19 tests is expected to decline in the second half of the yearIFRSnet income increases by 12% (12% in Swiss francs), whilecore earnings per share are up 11%Highlights in the second quarter:EU approvals ofPolivy (first-line treatment for aggressive form of blood cancer),Lunsumio (follic...
Source: Roche Media News - July 21, 2022 Category: Pharmaceuticals Source Type: news

[Ad hoc announcement pursuant to Art. 53 LR] Roche achieves good results in the first six months of 2022
Group sales up 5%1 at constant exchange rates (CER) and 5% in Swiss francsPharmaceuticals Divisionsales increase 3%; continued strong demand for new medicines to treat severe diseases; as expected, the impact of biosimilars slows down furtherDiagnostics Divisionsales grow 11%; ongoing strong base business; demand for COVID-19 tests is expected to decline in the second half of the yearIFRSnet income increases by 12% (12% in Swiss francs), whilecore earnings per share are up 11%Highlights in the second quarter:EU approvals ofPolivy (first-line treatment for aggressive form of blood cancer),Lunsumio (follicular lymphoma) andT...
Source: Roche Investor Update - July 21, 2022 Category: Pharmaceuticals Source Type: news

Transformational therapy cures haemophilia B
A patient on the trial says his life is now "completely normal", having grown up fearing getting hurt. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 20, 2022 Category: Consumer Health News Source Type: news

New data from phase III HAVEN 6 study reinforce favourable safety and efficacy profile of Roche ’s Hemlibra in people with moderate or mild haemophilia A
Hemlibra continues to demonstrate clinically meaningful bleed control, with 66.7% of participants with moderate or mildhaemophilia A experiencing zero treated bleeds at 55.6 weeks median follow-up [1]New data also reinforceHemlibra ’sfavourable safety profile, with no new safety signals observed [1]There is limited information and treatment guidance on moderate and mildhaemophilia A, which can lead to delayed or missed diagnoses of bleeding episodes [2]Hemlibra is approved to treat people of all ages withhaemophilia A with factor VIII inhibitors in more than 110 countries and for people of all ages without factor VIII in...
Source: Roche Media News - July 11, 2022 Category: Pharmaceuticals Source Type: news