Claims of a universal cure for cancer 'misleading'

Conclusion This research has demonstrated the unique abilities of the blind mole rat to resist cancer, even when directly given potent cancer-causing chemicals. In the laboratory, the researchers also demonstrated how connective tissue cells called fibroblasts taken from the animal seem to play an important role in this cancer resistance. These cells prevented the growth of human cancer cells when the two types of cells were grown together in the laboratory. A similar study in a closely related species – the naked mole rat – has also demonstrated similar cancer protection. Scientists have been studying the mole rat for many years. However, the biological underpinnings of the cancer resistance remain unclear. This serves as a reminder that these developments take time and persistence, and that the road to scientific breakthrough is typically long and incremental. This is a useful piece of research that could lead to potentially exciting new avenues of research. It is true that, as the researchers say, this is "pioneering" work, but it is a little too early to suggest that their findings present a "genuine breakthrough". Many discoveries in animal studies fail to show similar effects in humans, so even if the anti-cancer properties of the mole rat are discovered, there is no guarantee they will be useful or applicable to humans. Nonetheless, there remains optimism that understanding the anti-cancer mechanisms of mole rats may one day help ...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Source Type: news

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AbstractAccurate staging and re-staging of cancer in children is crucial for patient management. Currently, children with a newly diagnosed cancer must undergo a series of imaging tests, which are stressful, time-consuming, partially redundant, expensive, and can require repetitive anesthesia. New approaches for pediatric cancer staging can evaluate the primary tumor and metastases in a single session. However, traditional one-stop imaging tests, such as CT and positron emission tomography (PET)/CT, are associated with considerable radiation exposure. This is particularly concerning for children because they are more sensi...
Source: Pediatric Radiology - Category: Radiology Source Type: research
big dreamer here: if you were starting out as a first year med student, what is the path you’d take to secure a dream job specializing in lung cancer and related environmental research/advocacy at an academic medical center? what about while adding on an MBA and wanting to combine academia with entrepreneurship to find better lung cancer therapies?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Medical Students (MD) Source Type: forums
ConclusionsOur study confirms and extends our knowledge on the tyrosine kinase inhibitors effects on thyroid, showing that thyroid autoimmunity is frequently observed in chronic myeloid leukemia patients on long-term therapy and is associated with a better oncological response.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
PEOPLE adhering more strongly to a particular health diet have been found to have lower risks of dying from cancer and heart disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Source: Cancer Management and Research - Category: Cancer & Oncology Tags: Cancer Management and Research Source Type: research
Source: International Journal of General Medicine - Category: General Medicine Tags: International Journal of General Medicine Source Type: research
SATURDAY, Jan. 22, 2022 -- Tobacco use is far and away the leading cause of lung cancer, but non-smokers are also at risk, experts say. People who smoke have the highest risk, and smokeless tobacco is also a threat. About 90% of lung cancer cases...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Am J Pathol. 2022 Jan 18:S0002-9440(22)00006-2. doi: 10.1016/j.ajpath.2021.12.006. Online ahead of print.ABSTRACTAlthough Glycolysis plays a pivotal role in breast cancer stem-like cells (BCSCs) reprogramming, the molecular mechanisms that couple glycolysis to cancer stem-like cell remain unclear. The SET-domain containing 5 (SETD5) is a previously uncharacterized member of the histone lysine methyltransferase family. The goal of this study was to explore the mechanisms underlying the promotion of stem-like and glycolysis activation traits by SETD5. Previous study displayed that overexpression of SETD5 in breast cancer (BC...
Source: The American Journal of Pathology - Category: Pathology Authors: Source Type: research
In this study, we employed an integrative analysis framework of functional genomics approaches and machine learning methods to the lncRNA, miRNA, and mRNA data and identified 16 RNAs (3 lncRNAs, 6 miRNAs, and 7 mRNAs) of prognostic value with 9 of them novel. We then established a 16-RNA-based score for prognosis prediction of ccRCC with significance (p-value
Source: The American Journal of Pathology - Category: Pathology Authors: Source Type: research
Am J Pathol. 2022 Jan 18:S0002-9440(22)00006-2. doi: 10.1016/j.ajpath.2021.12.006. Online ahead of print.ABSTRACTAlthough Glycolysis plays a pivotal role in breast cancer stem-like cells (BCSCs) reprogramming, the molecular mechanisms that couple glycolysis to cancer stem-like cell remain unclear. The SET-domain containing 5 (SETD5) is a previously uncharacterized member of the histone lysine methyltransferase family. The goal of this study was to explore the mechanisms underlying the promotion of stem-like and glycolysis activation traits by SETD5. Previous study displayed that overexpression of SETD5 in breast cancer (BC...
Source: Am J Pathol - Category: Pathology Authors: Source Type: research
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