Viruses, Vol. 13, Pages 523: Three-Year Clinical Follow-Up of Children Intrauterine Exposed to Zika Virus
Viruses, Vol. 13, Pages 523: Three-Year Clinical Follow-Up of Children Intrauterine Exposed to Zika Virus
Viruses doi: 10.3390/v13030523
Authors:
Rosa Estela Gazeta
Ana Paula Antunes Pascalicchio Bertozzi
Rita de Cássia Aguirre Dezena
Andrea Cristina Botelho Silva
Thamirys Cosmo Gillo Fajardo
Daniel T. Catalan
Maria de Fátima Valente Rizzo
Antonio Fernandes Moron
Antoni Soriano-Arandes
Nuria Sanchez Clemente
Tania Quintella
Dora Fix Ventura
Francisco Max Damico
Valtenice de Cassia Rodrigues de Matos França
Juliana Paula Gomes de Almeida
Ana Laura de Sene Amâncio Zara
Lucas Castro Pires
Cohort Zika vírus Jundiaí
Saulo Duarte Passos
Congenital Zika virus (ZIKV) infection may present with a broad spectrum of clinical manifestations. Some sequelae, particularly neurodevelopmental problems, may have a later onset. We conducted a prospective cohort study of 799 high-risk pregnant women who were followed up until delivery. Eighty-three women and/or newborns were considered ZIKV exposed and/or infected. Laboratory diagnosis was made by polymerase chain reaction in the pregnant mothers and their respective newborns, as well as Dengue virus, Chikungunya virus, and ZIKV serology. Serology for toxoplasmosis, rubella, cytomegalovirus, herpes simplex virus, and syphilis infections were also performed in microcephalic newborns. The newborns included in the study were followed up until their third birthday. Developmental delay was observed in...
Source: Viruses - Category: Virology Authors: Rosa Estela Gazeta Ana Paula Antunes Pascalicchio Bertozzi Rita de C ássia Aguirre Dezena Andrea Cristina Botelho Silva Thamirys Cosmo Gillo Fajardo Daniel T. Catalan Maria de F átima Valente Rizzo Antonio Fernandes Moron Antoni Soriano-Arandes Nuria Sa Tags: Article Source Type: research
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