Scientists Identify 11 New Genetic Areas that Contribute to Alzheimer's Disease

The International Genomics of Alzheimer's Project Global Consortium Aims to Discover and Map all the Alzheimer's Genes and understand the role inheritance plays in Alzheimer's disease. +Alzheimer's Reading Room The largest international Alzheimer's disease genetics collaboration to date has found 11 new genetic areas of interest that contribute to late onset Alzheimer's Disease (LOAD), doubling the number of potential genetics-based therapeutic targets to interrogate. Subscribe to the Alzheimer's Reading Room Email: International Group Finds 11 New Alzheimer's Genes to Target for Drug Discovery, Adding New Clues Into Complex Disease PuzzleGlobal Collaboration Including Penn Medicine Experts Yields Fresh Look at Role of Immune System in Alzheimer's The study, published in Nature Genetics, provides a broader view of genetic factors contributing to the disease and expands the scope of disease understanding to include new areas including the immune system, where a genetic overlap with other neurodegenerative diseases such as multiple sclerosis and Parkinson's disease was identified. "Human genetic studies are being used with increased frequency to validate new drug targets in many diseases. Here we greatly increased the list of possible drug target candidates for Alzheimer’s disease, finding as many new significant genes in this one study as have been found in the last 15 years combined," said co-senior author Gerard Schellenberg, PhD, director of the Alzheimer’s ...
Source: Alzheimer's Reading Room, The - Category: Dementia Authors: Source Type: blogs