Clinical significance of Kelch-like protein 11 antibodies

Conclusions KLHL11-abs associate with a spectrum of syndromes and tumors wider than those previously reported; 44% of patients have concurrent neuronal antibodies, some of them (anti-NMDAR) pathogenically relevant. Brain immunostaining is not useful for routine screening of KLHL11-abs.

http://nn.neurology.org/cgi/content/short/7/3/e666?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - January 16, 2020 Category: Neurology Authors: Maudes, E., Landa, J., Munoz-Lopetegi, A., Armangue, T., Alba, M., Saiz, A., Graus, F., Dalmau, J., Sabater, L. Tags: Autoimmune diseases, All Clinical Neurology, Paraneoplastic syndrome Article Source Type: research