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Hemp seed oil may possibly (but not probably) cause cannabinoid poisoning
2.5 out of 5 stars Cannabinoid Poisoning by Hemp Seed Oil in a Child. Chinello M et al. Pediatr Emerg Care 2017;33:344-345. Abstract This interesting but non-dispositive short case report from Italy suggests that, in rare instances, commercially marketed hemp seed oil can cause mild cannabinoid toxicity. A 2-year-7-month old male was brought to hospital with altered mental status and several hours of “decreased alertness, refusal to walk, and no verbal response.” Additional findings included: “paleness, stupor, [and] low reactivity to stimulation.” Pulse rate was 129 bpm. There was no ataxia. The p...
Source: The Poison Review - May 10, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical cannabinoid cannabis hemp seed oil pediatric subacute poisoning Source Type: news

Treatment shows promise in models of fatal neurological disorders
A gene-silencing drug improved symptoms in mouse models of ataxia and amyotrophic lateral sclerosis. The results suggest a possible therapy for these untreatable neurological diseases. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 25, 2017 Category: Consumer Health News Source Type: news

p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM
Cellular systems show a wide range of signaling dynamics. Many of these dynamics are highly stereotyped, such as oscillations at a fixed frequency. However, most studies looking at the role of signaling dynamics focus on one or a few cell lines, leaving the diversity of dynamics across tissues or cell lines a largely unexplored question. We focused on the dynamics of the tumor suppressor protein p53, which regulates cell cycle arrest and apoptosis in response to DNA damage. We established live-cell reporters for 12 cancer cell lines expressing wild-type p53 and quantified p53 dynamics in response to double-strand break&nda...
Source: Signal Transduction Knowledge Environment - April 25, 2017 Category: Science Authors: Stewart-Ornstein, J., Lahav, G. Tags: STKE Research Articles Source Type: news

Gene silencing shows promise for treating two fatal neurological disorders
A drug, engineered to combat the gene that causes spinocerebellar ataxia type 2 (SCA2), might also be used to treat amyotrophic lateral sclerosis (ALS), researchers have demonstrated in two studies of mice. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 12, 2017 Category: Science Source Type: news

Gene silencing shows promise for treating two fatal neurological disorders
NIH-funded preclinical studies suggest designer drug may treat ALS and spinocerebellar ataxia 2. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - April 12, 2017 Category: American Health Source Type: news

What Are the Clinical Symptoms Associated with Friedreich Ataxia?
Discussion Friedreich ataxia (FRDA) was first extensively described in a series of papers from 1863-1877 by Nikolaus Friedreich at the University of Heidelberg, Germany. In 1996 the genetic mutation was described. It is an autosomal recessively inherited, homologous expansion of the GAA repeat in intron 1 of the frataxin gene on chromosome 9q13. It causes a transcription error leading to a decrease in frataxin which is a mitochondrial protein involved in iron metabolism and other cell functions. Frataxin is seen mainly in the central and peripheral nervous systems, heart, pancreas and skeleton. Frataxin is produced but in ...
Source: PediatricEducation.org - April 10, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Geelong mother opens up about rare inherited disease
Leah Alstin, from Geelong, was diagnosed with Friedreich's ataxia when she was 17 years old. The rare inherited disease progressively damages the nervous system. (Source: the Mail online | Health)
Source: the Mail online | Health - March 2, 2017 Category: Consumer Health News Source Type: news

Borna Disease Virus, Schizophrenia, Bipolar Disorder & Depression
This study closes the door on the relationship between BDV and mental illness in humans. There is no apparent connection between the Borna Disease Virus and schizophrenia, bipolar disorder, or depression.   References Bautista J R, Schwartz G J, de la Torre J C, Moran T H, Carbone K M. Early and persistent abnormalities in rats with neonatally acquired Borna disease virus infection. Brain Res Bull. 1994;34:31–40. Carbone, K. M. (2001). Borna Disease Virus and Human Disease. Clinical Microbiology Reviews, 14(3), 513–527. http://doi.org/10.1128/CMR.14.3.513-527.2001 Dittrich W, Bode L, Ludwig H, Kao M, Schne...
Source: Psych Central - February 2, 2017 Category: Psychiatry Authors: John M. Grohol, Psy.D. Tags: Bipolar Depression Disorders General Schizophrenia BDV behavioral symptoms Bipolar Disorder Borna disease virus borna virus Infectious disease Source Type: news

Fatal self-envenomation in a brown tree snake, Boiga irregularis, from South-east Queensland: a case report - Hill AG, McKillop L.
The case history and clinical signs of a fatal self-envenomation event by a brown tree snake, Boiga irregularis, in South-east Queensland, Australia, are presented. Clinical signs began 20 minutes post-envenomation with muscle twitching, ataxia, and heat s... (Source: SafetyLit)
Source: SafetyLit - December 26, 2016 Category: Global & Universal Tags: Non-Human Animals and Insects Source Type: news

SfN: Ballet Improves Ataxia in MS (CME/CE)
(MedPage Today) -- Dance program improved movement in pilot study (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - November 16, 2016 Category: Journals (General) Source Type: news

How Long Do Concussive Symptoms Last?
Discussion Concussion as defined by the International Conference on Concussion in Sport in 2012 is “Concussion is a brain injury and is defined as a complex pathophysiological process affecting the brain, induced by biomechanical forces.” It results in quick onset of signs and symptoms of physical and cognitive impairment. Concussion is sometimes referred to as mild traumatic brain injury (TBI) as mild TBI refers to “…concussions that are generally not life threatening despite the potential for short-term disability and serious ongoing sequelae.” Concussion symptoms are usually categorized as...
Source: PediatricEducation.org - October 31, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Unilateral Scleral Jaundice in an Elderly Man: An Odd Finding
Left scleral icterus is the only prominent physical finding in the 86-year-old who presented with transient aphasia, ataxia, and general asthenia. Can you dx? (Source: ConsultantLive)
Source: ConsultantLive - September 8, 2016 Category: Internal Medicine Authors: Ali Ahmadizadeh, MD Pharlin Noel, PA-C Source Type: news

When Is the Clinical Nadir for Guillain-Barr é Syndrome?
Discussion Guillian-Barré syndrome (GBS) is an acquired, acute, inflammatory, demyelinating polyneuropathy. It is the most common cause of acute and subacute flaccid paralysis in children. GBS causes about 0.4-1.3 cases per 100,000 persons/year in children. It can occur in any age group and the incidence increases among all age groups until a peak in the 50s. Both genders are affected and there may be a slight increase in males. GBS usually occurs 2-4 weeks after a prodromonal gastroenteritis or respiratory illness. It is most often associated with Campylobacter jejunae, Haemophilus infuenza, Mycoplasma pneumoniae,...
Source: PediatricEducation.org - August 8, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Horizon Pharma plc to Acquire Worldwide Rights to Interferon Gamma-1b From Boehringer Ingelheim International GmbH
Also Licenses Rights to Patents and Pending Applications Covering Methods for Treating Friedreich's Ataxia With Interferon Gamma-1b; Company Currently Owns the Rights to Interferon Gamma-1b Under the Trade Name ACTIMMUNE(R) in the United States, Canada and... Biopharmaceuticals, Licensing, AcquisitionsHorizon Pharma, Boehringer Ingelheim, interferon gamma-1b (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 19, 2016 Category: Pharmaceuticals Source Type: news

The interrelationship between disease severity, dynamic stability, and falls in cerebellar ataxia - Schniepp R, Schlick C, Pradhan C, Dieterich M, Brandt T, Jahn K, Wuehr M.
This study systematically correlated the clinical rat... (Source: SafetyLit)
Source: SafetyLit - May 19, 2016 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Immune system 'plays a role in dementia'
Conclusion This review presents evidence supporting the idea that the innate immune system is involved in a range of neurodegenerative conditions, such as Alzheimer's and Parkinson's. Reviews like this are very useful at summarising the current state of science in an area, but may miss important research, unless they are systematic. This review was openly one-sided, transparently exploring the evidence behind one hypothesis. While there is nothing wrong with that, a more systematic and balanced review would add the extra value of being able to discuss alternative ideas and find out how much evidence stacks up behind each...
Source: NHS News Feed - May 13, 2016 Category: Consumer Health News Tags: Neurology Older people Source Type: news

Horizon Pharma completes patent enrolment for Phase lll trial of actimmuneto treat Friedreich's Ataxia
Ireland-based biopharmaceutical company Horizon Pharma has completed its target enrolment of 90 patients for Phase lll trial of actimmune (interferon gamma-1b) to treat Friedreich's Ataxia (FA) disease. (Source: Drug Development Technology)
Source: Drug Development Technology - May 5, 2016 Category: Pharmaceuticals Source Type: news

Metronidazole-induced cerebellar syndrome
3.5 out of 5 stars Metronidazole-Associated Encephalopathy. Farmakiotis D, Zeluff B. N Engl J Med 2016 Apr 14;374:1465 Full Text            Exposure to metronidazole (Flagyl) can precipitate a subacute cerebellar syndrome, typically manifested with dysarthria and ataxia, with or without cognitive impairment. This adverse effect is uncommon and little-appreciated. Although usually associated with prolonged exposure to the antibiotic for treatment of conditions such as abscesses of Clostridium difficile-associated diarrhea and occurring after total cumulative dose> 20 gm, ...
Source: The Poison Review - April 15, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical acute cerebellar syndrome encephalopathy metronidazole miri neurotoxicity Source Type: news

UCLA research suggests that gut bacteria could help prevent cancer
Researchers have shown that various types of intestinal bacteria might be factors in both causing and preventing obesity, and in other conditions and diseases. Now, a UCLA study suggests that it could also potentially be used to reduce the risk for some types of cancer. The research, published online April 13 in the peer-reviewed journal PLOS ONE, offers evidence that anti-inflammatory “health beneficial” gut bacteria can slow or stop the development of some types of cancer. Ultimately, doctors might be able to reduce a person’s risk for cancer by analyzing the levels and types of intestinal bacteria in...
Source: UCLA Newsroom: Health Sciences - April 13, 2016 Category: Universities & Medical Training Source Type: news

Exome sequencing improves doctors’ ability to diagnose hard-to-pin-down neurogenetic disorders
UCLA researchers have found that a state-of-the-art molecular genetic test greatly improves the speed and accuracy with which they can diagnose neurogenetic disorders in children and adults. The discovery could lead directly to better care for people with rare diseases like spinocerebellar ataxia, leukodsystrophy, spastic paraplegia and many other conditions. The test, called exome sequencing, involves determining the order of all of the genes in a person’s genome. When used in concert with a complete patient evaluation and family medical history, the approach can help doctors identify disorders that may have gone un...
Source: UCLA Newsroom: Health Sciences - April 5, 2016 Category: Universities & Medical Training Source Type: news

Biodex fall risk assessment in the elderly with ataxia: a new age-dependent derived index in rehabilitation: an observational study - Prometti P, Olivares A, Gaia G, Bonometti G, Comini L, Scalvini S.
The aim of this study was to evaluate if the Biodex Fall Risk Assessment could provide an age-adjusted index useful for classifying patients at "risk of fall."This was a cohort study conducted on 61 chronic patients, in stable conditions, having a history ... (Source: SafetyLit)
Source: SafetyLit - March 25, 2016 Category: Global & Universal Tags: Age: Elder Adults Source Type: news

Genetic Cause of Spinocerebellar Ataxia (SCA) Identified
Researchers identify new mutation responsible for Spinocerebellar Ataxia (SCA), a degenerative and ultimately fatal movement disorder (Source: Disabled World)
Source: Disabled World - March 14, 2016 Category: Disability Tags: Medical Research Source Type: news

MedlinePlus: Ataxia telangiectasia
(Source: NLM General Announcements)
Source: NLM General Announcements - March 11, 2016 Category: Databases & Libraries Source Type: news

UT Southwestern scientists find potential treatment for Friedreich's ataxia
(UT Southwestern Medical Center) Researchers at UT Southwestern Medical Center have identified synthetic RNA and DNA that reverses the protein deficiency causing Friedreich's ataxia, a neurological disease for which there is currently no cure. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 16, 2016 Category: Biology Source Type: news

Children's Guaifenesin Grape Liquid and Guaifenesin DM Cherry Liquid by Perrigo Company: Recall - Potential Defect with Dosage Cup
An overdose of Guaifenesin DM may cause hyper excitability, rapid eye movements, changes in muscle reflexes, ataxia, dystonia, hallucinations, stupor, and coma. (Source: FDA MedWatch)
Source: FDA MedWatch - January 13, 2016 Category: American Health Source Type: news

Recall Issued For Children’s Cold Medicine
BOSTON (CBS) — A recall for a children’s cold medicine sold by retailers like CVS and Stop and Shop has been issued. In a release posted on the company’s website, Perrigo Company said they had issued a recall for two batches of their children’s guaifenesin grape liquid and three batches of their children’s guaifenesin DM cherry liquid. Both products are sold in 4 oz. bottles with a dosage cup included in the package. The recall was issued because the markings on some of the dosage cups are inaccurate–which could lead to overdoses. “There have been no reports of adver...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 12, 2016 Category: Consumer Health News Authors: Jon Palmer Tags: Health Local News Syndicated Local drug recall Perrigo Source Type: news

Miller Fisher Syndrome: General Overview & Information
Miller Fisher Syndrome or, 'MFS,' is a post-infectious, immune mediated neuropathy characterized in typical instances by the clinical triad of ataxia, areflexia and ophthalmoplegia. MFS is considered to be a variant of Guillain-Barre syndrome or, 'GBS.' The clinical symptoms usually develop within days and improve spontaneously or following treatment within a period of weeks. People with MFS often show only part of the clinical triad. (Source: Disabled World)
Source: Disabled World - December 22, 2015 Category: Disability Tags: Neurological Disorders Source Type: news

Certain herpes viruses can infect human neurons
(University of Pennsylvania School of Medicine) A tantalizing link exists between some neurologic conditions and certain species of herpes virus. In some patients with Alzheimer's disease, multiple sclerosis, and cerebellar ataxia, among others, the cerebrospinal fluid teems with Epstein-Barr virus. Yet, the link remains unclear. It's been assumed that EBV, and viruses in the same family cannot infect neurons. Now, researchers have shown that EBV and Kaposi's sarcoma-associated herpesvirus can infect and replicate in cultured and primary neurons. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 4, 2015 Category: Infectious Diseases Source Type: news

Genetic defect underlying a rare disease identified
The genetic cause has been identified for a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when the patient reaches school age. In 2007 the same researchers published a mutation in the Scyl1 gene in a naturally occurring mouse mutant with similar symptoms. Using next-generation sequencing techniques, they have now succeeded in identifying the first cases of a corresponding condition in humans. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 13, 2015 Category: Science Source Type: news

Genomics Moves From the Lab to the Doctor's Office
By Diana Brazzell, Co-Founder & Executive Editor, Footnote This post was originally published on Footnote, a website that brings academic research and ideas to a broader audience. Since the discovery of DNA, people have anticipated how deciphering the secrets in our genes might one day transform medicine. The first commonly used genetic tests appeared in the 1970s and the full human genome was sequenced in 2003. But it is only in the past decade, as sequencing technology advanced rapidly and the price tag plummeted, that genomic medicine has started to become a reality.(a) We're finally gaining access to a huge piece...
Source: Science - The Huffington Post - October 15, 2015 Category: Science Source Type: news

Autoimmune Cerebellar Ataxia May Respond to ImmunotherapyAutoimmune Cerebellar Ataxia May Respond to Immunotherapy
A new study of patients with autoimmune cerebellar ataxia, often a complication of cancer, has found it is not always untreatable and that many patients respond well to immunotherapy, particularly if started early. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - September 30, 2015 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Autoimmune cerebellar ataxia
(Mayo Clinic) While autoimmune cerebellar ataxia (a loss of muscle control coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help predict better immunotherapy response, according to the Mayo Clinic study published by JAMA Neurology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 29, 2015 Category: Global & Universal Source Type: news

Autoimmune cerebellar ataxia: Study finds treatment promises for a disease previously considered hopeless
ROCHESTER, Minn. — While autoimmune cerebellar ataxia (a loss of muscle control coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help predict better immunotherapy response, according to the Mayo Clinic study published by JAMA Neurology. https://www.youtube.com/watch?v=tsriW0BD638 Autoimmune cerebellar ataxia in adults, which usually comes on rapidly and [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - September 29, 2015 Category: Databases & Libraries Source Type: news

Coordinating traffic down the neuronal highway
An international team of researchers has identified a protein that regulates the growth of neurons by transporting key metabolic enzymes to the tips of neural cells. Their findings open up new avenues for design of drugs for ataxia, a motor coordination disorder. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 18, 2015 Category: Science Source Type: news

Coordinating traffic down the neuronal highway
A protein that regulates the growth of neurons by transporting key metabolic enzymes to the tips of neural cells has been identified by an international team of researchers. Their findings open up new avenues for design of drugs for ataxia, a motor coordination disorder. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 18, 2015 Category: Science Source Type: news

University of South Florida and Friedreich's Ataxia Research Alliance to host scientific symposium
(University of South Florida (USF Health)) The University of South Florida will again bring together leading researchers and patients searching for a treatment for Friedreich's ataxia and related disorders at the seventh annual scientific symposium 'Understanding Energy for A Cure.' The symposium will be held 5:00 to 8:30 p.m., Thursday, Sept. 17, at the USF Marshall Student Center Ballroom in Tampa, FL. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 1, 2015 Category: Global & Universal Source Type: news

Henry Barber-Riley staggers around, slurs his words and vomits due to rare genetic condition
Henry Barber-Riley, five, from Lutterworth, Leicstershire, suffers from episodic ataxia type 2, which causes him to have 'episodes' in which he staggers and slurs his words. (Source: the Mail online | Health)
Source: the Mail online | Health - August 25, 2015 Category: Consumer Health News Source Type: news

More falls in cerebellar ataxia when standing on a slow up-moving tilt of the support surface - Paquette C, Franzén E, Horak FB.
We investigated how subjects with cerebellar ataxia (CA) adapt their postural stability and alignment to a slow and small tilt of the support surface allowing for online postural corrections. Eight subjects with CA and eight age- and gender-matched healthy... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - August 7, 2015 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Decreasing fall risk in spinocerebellar ataxia - Santos de Oliveira LA, Martins CP, Horsczaruk CH, Lima da Silva DC, Martins JV, Vasconcelos LF, Rodrigues Ede C.
[Purpose] Spinocerebellar ataxia consists of a group of autosomal dominant disorders that cause progressive degeneration, mainly in the cerebellum and its connections. Falls, which are a significant concern of this condition, reduce patients' mobility, det... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - July 22, 2015 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Ataxia mouse model: Eye blink conditioning for early diagnosis of human disease SCA6
Scientists have established a mouse model for the human disease SCA6. SCA6 is characterized by movement deficits and caused by similar genetic alterations as Chorea Huntington. The mouse model will be used to investigate the disease mechanisms. Experiments suggest that an impairment of eye blink conditioning could be an early disease symptom. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 17, 2015 Category: Science Source Type: news

Ataxia with Parkinsonism and dystonia after intentional inhalation of liquefied petroleum gas - Godani M, Canavese F, Migliorini S, Sette MD.
The practice of inhaling liquefied petroleum gas (LPG) to commit suicide is uncommon and almost exclusively a prerogative of the prison population. Numerous cases of sudden deaths caused by intentional propane and/or butane inhalation have been described, ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - June 10, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Is Gluten Sensitivity Real?
"If you don't have celiac disease, it makes no sense to be on a gluten-free diet," remains a common refrain from physicians and other health care providers who choose to deny the idea that people who don't carry a diagnosis of celiac disease can have health issues from consuming gluten. Nonetheless, the idea that sensitivity to gluten, a protein found in wheat barley and rye, can indeed relate to medical problems has developed incredible traction in our society, as evidenced by the impressive growth in sales of gluten-free foods. Foods labeled as "gluten-free" have increased in sales an average of 34 p...
Source: Healthy Living - The Huffington Post - June 8, 2015 Category: Consumer Health News Source Type: news

Horizon Pharma begins Actimmune’s Phase III trial for Friedreich's Ataxia
Ireland-based Horizon Pharma has started the Phase III study of Actimmune (interferon gamma-1b) to treat patients with Friedreich's Ataxia (FA), a degenerative neuro-muscular disorder. (Source: Drug Development Technology)
Source: Drug Development Technology - June 7, 2015 Category: Pharmaceuticals Source Type: news

Minor trauma causing stroke in a young athlete - Gupta V, Dhawan N, Bahl J.
A 17-year-old Caucasian male presented with sudden dizziness, ataxia, vertigo, and clumsiness lasting for a couple of hours. He had a subtle trauma during a wrestling match 2 days prior to the presentation. A CT Angiogram (CTA) and MRI showed left vertebra... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - April 24, 2015 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Gene editing technique could prevent inherited diseases
ConclusionThis early research has developed a new technique to reduce the amount of mutation-carrying DNA within mitochondria. The hope is that this technique might be used in the eggs of women carrying disease-causing mitochondrial mutations.The government has recently given the go ahead for a technique that allows a woman who carries such a disease from passing it on to her child – making the UK the first country to do so. This technique has raised some ethical and safety concerns, as it places the woman’s chromosomes into a donor egg with healthy mitochondria. This means that once this egg is fertilised...
Source: NHS News Feed - April 24, 2015 Category: Consumer Health News Tags: Genetics/stem cells Pregnancy/child Source Type: news

Horizon Pharma's Friedreich's Ataxia Drug Gets Fast-Track Designation
Horizon Pharma PLC said Friday that its experimental Friedreich’s ataxia treatment has received fast-track designation from the U.S. Food and Drug Administration, a move that could speed approval. (Source: WSJ.com: Health)
Source: WSJ.com: Health - April 10, 2015 Category: Pharmaceuticals Tags: PAID Source Type: news

Horizon Pharma plc Receives FDA Fast Track Designation for ACTIMMUNE(R) in the Treatment of Friedreich's Ataxia
DUBLIN, IRELAND--(Healthcare Sales & Marketing Network) - Horizon Pharma plc (NASDAQ: HZNP), a specialty biopharmaceutical company focused on improving patients' lives by identifying, developing, acquiring and commercializing differentiated products that a... Biopharmaceuticals, Neurology, FDAHorizon Pharma, ACTIMMUNE, Friedreich's Ataxia (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 10, 2015 Category: Pharmaceuticals Source Type: news

[Editors' Choice] GABA receptors as oxytocin targets
Oxytocin limits the ataxia and sedation effects of ethanol by reducing its potentiation of the GABAA family of Cl- channels. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 19, 2015 Category: Science Authors: Nancy Gough (mailto:ngough at aaas.org) Source Type: news

Ataxia: Types, Causes & Symptoms
The word, ‘ataxia,’ describes a lack of muscle control during voluntary movements such as picking up objects or walking. A sign of an underlying condition, ataxia may affect a person’s speech, eye movement, physical movements and swallowing. ‘Persistent ataxia,’ often times results from damage to a person’s cerebellum, the portion of the brain that controls coordination. Many conditions can cause ataxia to include: (Source: Disabled World)
Source: Disabled World - March 5, 2015 Category: Disability Tags: Health and Disability Source Type: news

Horizon Pharma plc Submits Investigational New Drug Application for ACTIMMUNE(R) in the Treatment of Friedreich's Ataxia
Phase 3 Study Expected to Begin in Q2 2015 DUBLIN, IRELAND--(Healthcare Sales & Marketing Network) - Horizon Pharma plc (HZNP), a specialty biopharmaceutical company focused on improving patients' lives by identifying, developing, acquiring and commerci... Biopharmaceuticals, Neurology, FDAHorizon Pharma, ACTIMMUNE, Friedreich's Ataxia (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 13, 2015 Category: Pharmaceuticals Source Type: news