Study supports benefit of statin use for older adults

In this study, the most common reason that patients or their doctors stopped statins was the development of advanced cancer or other major illness. In my practice, I have also cared for many patients who have stopped taking statins or who express reluctance to take statins due to side effects. The most common side effect is muscle ache (typically tenderness or soreness of the large muscle groups, such as the biceps and thighs), which affects about 20% of statin takers and reverses when the statin is discontinued. There is also a slightly increased risk of diabetes with long-term statin use and, very rarely, liver problems. Other potential (but uncommon) side effects include cognitive problems, such as short-term memory loss and confusion, although statins actually decrease the long-term risk of dementia due to stroke or Alzheimer’s disease. Study tips the scale in favor of continued statin use in older adults Most primary care doctors and cardiologists prescribe statins according to the current guidelines. However, because these guidelines are vague when it comes to treating those over 75, there is variability when it comes to prescribing to this population. Several factors weigh into the decision. For example, many doctors (and patients) are not convinced that statins will provide any benefit in older patients, because most of our knowledge comes from studying middle-aged subjects. In addition, in older patients who may have more medical illnesses and take more medicat...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Drugs and Supplements Health Healthy Aging Heart Health Source Type: blogs

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Publication date: Available online 9 December 2019Source: European UrologyAuthor(s): Christian Radmayr
Source: European Urology - Category: Urology & Nephrology Source Type: research
ConclusionIndiana pouch is a successful continence urinary reservoir with a reproductible technique, however long-term observation is needed.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionDirect-to-implant IBR after skin-sparing mastectomy is a viable option for breast cancer patients undergoing neoadjuvant chemotherapy.ResumenIntroducciónLa reconstrucción inmediata (RMI) tras mastectomía en pacientes que han recibido quimioterapia neoadyuvante (QTNA) sigue siendo controvertida. El objetivo de este estudio es analizar y comparar resultados oncológicos y las tasas de complicaciones y reintervención en pacientes sometidas a QTNA y un grupo control.MétodosAnálisis observacional retrospectivo de casos-controles. Pacientes con cáncer de mama inter...
Source: Cirugia Espanola - Category: Surgery Source Type: research
CONCLUSIONS Silicone oil endotamponade in PPV was associated with an increased risk of IOP at 24-month follow-up. PMID: 31811816 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
In this study, we aimed to investigate the potential mechanism of PRSS3 dysregulation in PC. In this research, low miR-217 and high circ-ADAM9 expression were found in PC tissues and cell lines, which was closely associated with advanced clinical stage and lymph node metastasis. Patients with low miR-217 or high circ-ADAM9 expression had shorter survival time than those with high miR-217 or low circ-ADAM9 expression. Functionally, manipulation of miR-217 and circ-ADAM9 expression showed opposite effects on cell proliferation, migration and invasion. Stepwise mechanism studies indicated that circ-ADAM9 alleviated the inhibi...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Publication date: Available online 9 December 2019Source: Annals of Physical and Rehabilitation MedicineAuthor(s): I Laffont, J Froger, C Jourdan, K Bakhti, LEH Van Dokkum, A Gouaich, HY Bonnin, P Armingaud, A Jaussent, MC Picot, E Le Bars, A Dupeyron, C Arquizan, A Gelis, D MottetAbstractBackground. Few rehabilitation methods have proven their efficacy in increasing sensori-motor recovery and/or function of the upper limb (UL) after stroke. Video games (VGs) are promising tools in this indication.Objective. To compare UL rehabilitation by using VGs and conventional rehabilitation (CR) in patients with sub-acute stroke.Des...
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Publication date: Available online 9 December 2019Source: Journal of Functional FoodsAuthor(s): Milkica Grabež, Ranko Škrbić, Miloš P. Stojiljković, Vesna Rudić-Grujić, Marija Paunović, Aleksandra Arsić, Snježana Petrović, Vesna Vučić, Bosa Mirjanić-Azarić, Katarina Šavikin, Nebojša Menković, Teodora Janković, Nađa VasiljevićAbstractPomegranate peel contains high levels of various phytochemicals. We evaluated the effects of pomegranate peel extract (PoPEx) consumption on plasma lipid profile, fatty acids (FA) level and blood pressure (BP) in patients with diabetes mellitus type ...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
But the new guidance may not have a big impact on price, despite the agency's pronouncements.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
Publication date: Available online 9 December 2019Source: NeuropsychologiaAuthor(s): Fang Wang, Urs MaurerAbstractHow and when top-down information modulates visual-orthographic processing is an essential question in reading research. In a previous study, we showed that task modulation of print-tuning started at around 170 ms after stimulus presentation in the N1 offset of the ERP, while the N1 onset was yet unaffected. Here we test how prior category-level expectation affects visual-orthographic processing. Familiar, left/right-structured Chinese characters and stroke number matched, unfamiliar Korean characters were pr...
Source: Neuropsychologia - Category: Neurology Source Type: research
BOSTON (CBS) — According to a new study published in the journal Cancer, even light to moderate alcohol intake has been linked to a higher risk of cancer. Researchers at the University of Tokyo and the Harvard T.H. Chan School of Public Health looked at data on over 60,000 cancer patients in Japan. They found drinking as little as one drink a day for 10 years or two drinks a year for five years, was associated would increase overall cancer risk by five percent, such as cancers of the colon, stomach, breast, prostate, and esophagus. Cancer risk was lowest with no alcohol consumption.
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Seen On WBZ-TV Syndicated Local Cancer Dr. Mallika Marshall Drinking Source Type: news
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