Washington State Limits Exemptions for Children Not Being Vaccinated

(VANCOUVER, Wash.) — Parents in Washington state will no longer be able to claim a personal or philosophical exemption for their children from receiving the combined measles, mumps and rubella vaccine before attending a day care center or school under a measure signed Friday by Gov. Jay Inslee. The state saw more than 70 cases of measles this year, and Inslee signed the bill at Vancouver City Hall, in the county where most of those cases were centered. The new law takes effect at the end of July. Inslee said that while the bill was an important step in public health, he warned it doesn’t do “everything necessary to protect the health of our most vulnerable citizens.” “We should be listening to science and medicine, not social media,” he said. “It is science and truth that will keep us healthy rather than fear.” The Centers for Disease Control and Prevention has reported that as of the end of last week, 764 cases of measles have been confirmed in 23 states. Washington is among 17 states that allow some type of non-medical vaccine exemption for personal or philosophical beliefs. In addition, medical and religious exemptions exist for attendance at the state’s public or private schools or licensed day-care centers. Medical and religious exemptions remain in place under the measure passed by the Legislature last month. Unless an exemption is claimed, children are required to be vaccinated against or show proof of acquired imm...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized measles onetime washington Source Type: news

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Publication date: Available online 24 May 2019Source: Canadian Journal of CardiologyAuthor(s): Riina M. Kandolin, Christiane C. Wiefels, Cláudio Tinoco Mesquita, Aun-Yeong Chong, Paul Boland, David Glineur, Louise Sun, Rob S. Beanlands, Lisa M. MielniczukAbstractThis review describes the current evidence and controversies for viability imaging to direct revascularization decisions and the impact on patient outcomes. Balancing procedural risks and possible benefit from revascularization is a key question in patients with heart failure of ischemic origin (IHF). Different stages of ischemia induce adaptive changes in m...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
ConclusionTo that end, a KID syndrome cell line (KID-KC) was established from primary keratinocytes of a KID syndrome patient with heterozygous p.D50N mutation, which displayed impaired gap junction intercellular communication and hyperactive hemichannels, confirmed by dye transfer, patch clamp and neurobiotin uptake assays. In KID-KCs, treatment with AS-siRNA led to robust inhibition of the mutant GJB2 allele without altering expression of the wildtype allele. This resulted in correction of both gap junction intercellular communication and hemichannel activity. Furthermore, AS-siRNA treatment caused only low-level off-tar...
Source: Cytotherapy - Category: Cytology Source Type: research
ConclusionWe have used MSC-exo via intranasal administration to treat both BTBR and shank3 KO mice. The behavioral effect seemed 3 weeks post the treatment.The behavioral amelioration was seen in all the core symptoms including social interaction, repetitive behaviors, and vocal communication.
Source: Cytotherapy - Category: Cytology Source Type: research
ConclusionWe used gold nanoparticles loaded exosomes for in-vivo neuroimaging and present specific migration and homing to various brain pathologies including stroke, Parkinson's, Alzheimer's, Autism and healthy brains as a control. By this method, we visualized the migration and homing abilities of exosomes in long-term follow-up ad report that in pathological areas they home for more than 96 hours while in healthy brains they are being evacuated within 24 hours. Furthermore, we show that MSC-exo uses chemotaxis signaling to target the inflammatory areas in the brain.
Source: Cytotherapy - Category: Cytology Source Type: research
Conclusion MTDWe conducted a two-cohort, open-label study of the timing of toci on CTL019-associated CRS. Pts were 1-24 yo with CD19-expressing relapsed or refractory B-cell acute lymphoblastic leukemia (r/r B-ALL). CTL019 was manufactured at the UPenn Cell and Vaccine Production Facility. Enrolled pts were assigned to high (≥ 40%) or low (38.5 C measured twice in 24 hours (“early toci”) and subsequently treated per standard CRS algorithm. Primary endpoint: frequency of gr4 CRS (Penn scale) in ≤5/15 pts. Secondary endpoints: D28 tumor response, remission duration, additional toxicities.RES78 pts were scre...
Source: Cytotherapy - Category: Cytology Source Type: research
ConclusionStromal vascular fraction (SVF) therapy has been performed over the past seven years to treat 493 patients by our group in five clinical centers. SVF was isolated from the lipoaspirate collected from each respective patient through a simple manual liposuction procedure. For each patients, blood was drawn as well to isolate platelet-rich plasma (PRP). SVF and PRP were administered to all subjects by intravenous (IV) injection in an autologous manner, with minority group within the population received an additional spinal, intra-articular, or subcutaneous injections, or combination of several injection sites. The t...
Source: Cytotherapy - Category: Cytology Source Type: research
Conclusion MethodsThis study was conducted on 18 eyes of 18 volunteers with retinitis pigmentosa, The cells delivery with peribulbar injection method. Clinical examinitation, visus and fundus examination, multifocal electroretinography were performed before and after an peribulbar injection of approximately one-million UC-MSC. The patients were followed in 1 hour, 24 hours and 1 month for safety evaluation.Results: There are adverse events, like edema under the eyes, were observed in eyes all patients 1 hour after transplantation of UC-MSCs. The edema will disappear within 24 hours. These patients reported improvements in ...
Source: Cytotherapy - Category: Cytology Source Type: research
ConclusionFor the trial, 3 lots of hCT-MSCs were manufactured from cord tissue obtained from 3 term healthy male babies delivered after elective routine C-section. After transporting the cord to the Robertson GMP Laboratory, the tissue was cut and digested in a tissue dissociator. The resulting cell suspension was plated in tissue culture flasks for P0 culture in Prime-XV MSC Expansion XSFM culture medium (Irvine Scientific) supplemented with 1% platelet lysate (PL). After harvest, P0 cells were cryopreserved, with a subset of cells expanded for P1 in XSFM without PL, and with a larger cryopreservation and expansion proces...
Source: Cytotherapy - Category: Cytology Source Type: research
ConclusionNeoSERA is produced in Japan, considered to be a negligible bovine spongiform encephalopathy (BSE) risk country. We obtain adult donor bovine blood from animal less than 36 months old according to the regulation of EMA for BSE (EMA/410/01 rev.3). Using apheresis medical devices with closed disposable kits, sterile platelet-rich plasma (PRP) is collected from healthy donor bovine receiving a regular veterinary check. After stimulation and removal of coagulated fibrin by centrifugation, NeoSERA is collected in a completely closed system. To meet the scope of directives that apply to produce medicinal products from ...
Source: Cytotherapy - Category: Cytology Source Type: research
Publication date: Available online 23 May 2019Source: Neuroscience LettersAuthor(s): Na Wang, Dan-dan Wang, Ying ShenAbstractProtein Numb localizes to clathrin-coated vesicles and participates in the trafficking of trans-membrane receptors. We previously reported that Numb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor 1 (mGlu1) and motor coordination. However, the functions of Numb in other brain regions have not been investigated. Here, we show that Numb regulates the membrane expression of metabotropic glutamate receptor 5 (mGlu5) and is critical to social behavior...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
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