Overexpression of FER1L4 promotes the apoptosis and suppresses epithelial-mesenchymal transition and stemness markers via activating PI3K/AKT signaling pathway in osteosarcoma cells.

In conclusion, the study indicated that FER1L4 acted as a tumor suppressor in osteosarcoma via activating PI3K/AKT pathway may be a new prognostic biomarker and potential therapeutic target for osteosarcoma intervention. PMID: 31000382 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31000382?dopt=Abstract

Source: Pathology, Research and Practice - April 5, 2019 Category: Pathology Authors: Ma L, Zhang L, Guo A, Liu LC, Yu F, Diao N, Xu C, Wang D Tags: Pathol Res Pract Source Type: research