Clinical and Biological Implications of Mutational Spectrum in Acute Myeloid Leukemia of FAB Subtypes M0 and M1

Conclusions: Our study provided new insights into the mutational spectrum and molecular signatures of AML-M0 and M1. We proposed thatFLT3-ITD,NPM1 andTP53 be identified as markers for risk stratification of AML-M0 and M1. Patients with AML-M0 and M1 would likely benefit from allo-HSCT.Cell Physiol Biochem 2018;47:1853 –1861
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research