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Inflammation in CNS Neurodegenerative Diseases.

This article is protected by copyright. All rights reserved. PMID: 29513402 [PubMed - as supplied by publisher]
Source: Immunology - Category: Allergy & Immunology Authors: Tags: Immunology Source Type: research

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CONCLUSION: Dutch incidence and cost estimates based on claims were consistent with previous estimates. Prevalence estimates were somewhat higher. Drug and hospital costs were highest shortly after the diagnosis. Healthcare consumption related to comorbidities was in-line with the previously reported comorbidity estimates. PMID: 29775086 [PubMed - as supplied by publisher]
Source: Journal of Comparative Effectiveness Research - Category: General Medicine Tags: J Comp Eff Res Source Type: research
DEMENTIA signs and symptoms include memory loss, confusion in conversations and losing interest in hobbies. There are several different types of the condition including dementia with lewy bodies and vascular dementia. Alzheimer ’s disease is the most common form of the disease. This is how long you could live if you have the condition, according to the Alzheimer’s Society.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ConclusionThis study demonstrated that intravenous dexmedetomidine during hernia repair with local anesthesia is safe and the results were satisfactory to both operators and patients.
Source: Hernia - Category: Sports Medicine Source Type: research
ConclusionThe presented missions contribute significantly to an improvement in local healthcare and decrease the burden of disease. We were able to show the sustainable character of these surgical missions. As a next step, we will analyse the cost-effectiveness of MSTs.
Source: Hernia - Category: Sports Medicine Source Type: research
Authors: Sauerbier A, Aris A, Lim EW, Bhattacharya K, Ray Chaudhuri K Abstract Parkinson disease (PD) affects people of all races and ethnicity worldwide. PD is a multineurotransmitter and multisystem disorder and our current concept of the natural history of PD has changed considerably over the past decades. Many aspects of this heterogeneous condition still remain unexplained; one aspect that is poorly studied is the role of ethnicity and manifest motor and non-motor PD. Some preliminary data suggest that the prodromal risk of developing PD, clinical symptom expression and the experience of living with the condit...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Authors: Titova N, Chaudhuri KR Abstract Most patients with Parkinson disease (PD) have non-motor symptoms (NMS), and on average these can range from four to 19 different symptoms. NMS dominate the prodromal phase of PD and some may serve as clinical biomarkers of PD. NMS can be dopaminergic, non-dopaminergic, of genetic origin or drug induced. Clinical assessment of NMS should include the NMS Questionnaire (completed by patients) for screening, as recommended by the International Parkinson and Movement Disorders Society and other international societies. The total number of NMS in a patient with PD constitutes the...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
James Parkinson's Essay on the shaking palsy, 1817-2017. Med J Aust. 2018 May 21;208(9):384-386 Authors: Toodayan N PMID: 29764348 [PubMed - in process]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Authors: Chew EG, Foo JN, Tan EK PMID: 29764346 [PubMed - in process]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Authors: Kohsaka S, Katada J, Saito K, Terayama Y Abstract OBJECTIVE: To investigate the risk of bleeding events and stroke/systemic embolism (SE) among Japanese patients with nonvalvular atrial fibrillation (NVAF), focusing on the initial dosage of apixaban and patient age. METHODS: This retrospective cohort study used de-identified electronic health records-based claims data from 314 acute-care hospitals in Japan. NVAF patients newly initiated on warfarin or apixaban, with no prescription during the 180-day blanking period, were eligible. Patients were allocated to receive warfarin or 5 or 2.5 mg twice...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
This article reviews the salient features about the mode of action, efficacy, safety and tolerability profile of approved oral DMTs in RRMS and reviews their place in clinical algorithms in the Middle East and North Africa (MENA) region. We conducted a systematic review using a comprehensive search of MEDLINE, PubMed, Cochrane Database of Systematic Reviews (period January 1, 1995 thru January 31, 2018). Additional searches of American Academy of Neurology and European Committee for Treatment and Research in Multiple Sclerosis abstracts from 2012 thru 2017 were performed, in addition to searches of the Food and Drug Admini...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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