Enhancing the clinical utility of DriveSafe DriveAware for people with Huntington's disease - Sondhu MK, Fisher F, Stout JC.
DriveSafe DriveAware (DSDA) is a cognitive screening tool assessing driving safety. Previously, we found DSDA categorised some HD participants as 'likely to pass' on-road assessments, despite displaying cognitive impairments in domains known to impact driv... (Source: SafetyLit)
Source: SafetyLit - October 9, 2020 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

The magical new Chinese Garden at the Huntington is the getaway you need right now
The final phase of the Huntington's famed Chinese Garden is scheduled to open Oct. 9, with an additional 11.5 acres, or 15 acres total with new pavilions, landscaping and — someday — even restaurants. (Source: L.A. Times - Health)
Source: L.A. Times - Health - October 8, 2020 Category: Consumer Health News Authors: Jeanette Marantos Source Type: news

How to keep Trader Joe's orchids alive and other tips from the Huntington's expert
The No. 1 reason people kill their orchids is they overwater them. An expert offers tips on how to keep them alive. (Source: L.A. Times - Health)
Source: L.A. Times - Health - October 2, 2020 Category: Consumer Health News Authors: Lisa Boone Source Type: news

Michelle Gray Tracks Huntington ’s in Different Brain Cells
The University of Alabama at Birmingham neuroscientist aims to determine which cells are most important in prompting the disease ’s initiation and progression. (Source: The Scientist)
Source: The Scientist - October 1, 2020 Category: Science Tags: Scientist to Watch Source Type: news

Disrupted Glycosylation Causes Neurodegeneration Disrupted Glycosylation Causes Neurodegeneration
This paper discusses dysfunction of glycosyltransferases as a factor and potential therapeutic target in neurodegenerative diseases including ALS, Alzheimer, Huntington, and Parkinson disease.Brain (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 22, 2020 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Dementia symptoms: Does this happen to your face? It could be a sign of brain decline
DEMENTIA comes in many different forms and the range of possible symptoms reflects this. The main warning sign of Huntington's disease - a type of dementia - is associated with the face. (Source: Daily Express - Health)
Source: Daily Express - Health - September 15, 2020 Category: Consumer Health News Source Type: news

California's creek fire creates its own pyrocumulonimbus cloud
(NASA/Goddard Space Flight Center) On Friday September 4, 2020 at about 6:44 PM PDT the Creek Fire began in the Big Creek drainage area between Shaver Lake, Big Creek and Huntington Lake, Calif. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 8, 2020 Category: Biology Source Type: news

The rotten-smelling corpse flower is about to bloom. Here's how to watch it live.
The corpse flower blooms rarely and briefly at the Huntington. Watch it unfurl live on YouTube. (Source: L.A. Times - Health)
Source: L.A. Times - Health - August 28, 2020 Category: Consumer Health News Authors: Lisa Boone Source Type: news

The rotten-smelling corpse flower is about to bloom. Here's how to watch it live
The corpse flower blooms rarely and briefly at the Huntington. Watch it unfurl live on YouTube. (Source: L.A. Times - Health)
Source: L.A. Times - Health - August 28, 2020 Category: Consumer Health News Authors: Lisa Boone Source Type: news

A second L.A. Metro bus driver has died of complications from COVID-19
The driver, a 22-year veteran of the agency, most recently drove on Line 611, through Cudahy and Huntington Park. (Source: L.A. Times - Health)
Source: L.A. Times - Health - August 27, 2020 Category: Consumer Health News Authors: Laura J. Nelson Source Type: news

An early start to Huntington's disease
(Source: ScienceNOW)
Source: ScienceNOW - August 12, 2020 Category: Science Authors: DiFiglia, M. Tags: Neuroscience perspective Source Type: news

Huntingtons disease alters human neurodevelopment
Although Huntington’s disease is a late-manifesting neurodegenerative disorder, both mouse studies and neuroimaging studies of presymptomatic mutation carriers suggest that Huntington’s disease might affect neurodevelopment. To determine whether this is actually the case, we examined tissue from human fetuses (13 weeks gestation) that carried the Huntington’s disease mutation. These tissues showed clear abnormalities in the developing cortex, including mislocalization of mutant huntingtin and junctional complex proteins, defects in neuroprogenitor cell polarity and differentiation, abnormal ciliogenesis, ...
Source: ScienceNOW - August 12, 2020 Category: Science Authors: Barnat, M., Capizzi, M., Aparicio, E., Boluda, S., Wennagel, D., Kacher, R., Kassem, R., Lenoir, S., Agasse, F., Braz, B. Y., Liu, J.-P., Ighil, J., Tessier, A., Zeitlin, S. O., Duyckaerts, C., Dommergues, M., Durr, A., Humbert, S. Tags: Development, Medicine, Diseases, Neuroscience r-articles Source Type: news

Biotech Vico Therapeutics raises $31 million (€27 million) in Series A financing round to advance therapies for rare central nervous system diseases
AON-platform with focus on therapies nearing phase I trials for forms of Spinocerebellar Ataxia and Huntington Disease Other early discovery stage RNA editing platform focuses on RETT syndrome Funding led by LSP, co-led by Kurma Partners, supported b... Biopharmaceuticals, Neurology, Venture Capital Vico Therapeutics, RNA modulating therapies (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 29, 2020 Category: Pharmaceuticals Source Type: news

Church services move to California beaches, sparking fears of coronavirus outbreaks
Huntington Beach and Cardiff State Beach in San Diego County have both seen large outdoor church gatherings, alarming public health officials. (Source: L.A. Times - Health)
Source: L.A. Times - Health - July 28, 2020 Category: Consumer Health News Authors: Alex Wigglesworth, Paul Sisson Source Type: news

Food giveaway in Fountain Valley helps families deal with coronavirus
The Boys & Girls Clubs of Huntington Valley put on a food giveaway at Fountain Valley Recreation Center and Sports Park to help out families in need during the coronavirus pandemic. (Source: L.A. Times - Health)
Source: L.A. Times - Health - July 27, 2020 Category: Consumer Health News Authors: Andrew Turner Source Type: news

'I don't believe it': Huntington Beach a symbol of mask resistance as doubters abound
As infection rates soar in Orange County, residents of Surf City doubt the severity of the pandemic and call for easing restrictions. (Source: L.A. Times - Health)
Source: L.A. Times - Health - July 22, 2020 Category: Consumer Health News Authors: Jake Sheridan Source Type: news

Huntington Beach's Great Pacific Airshow canceled over coronavirus concerns
Organizers announced that the spectacle, scheduled for Sept. 18-20, would not take place due to the COVID-19 pandemic. (Source: L.A. Times - Health)
Source: L.A. Times - Health - July 22, 2020 Category: Consumer Health News Authors: Sara Cardine Source Type: news

Study reveals intricate details about Huntington's disease protein
(University at Buffalo) The research focuses on axonal transport --   the way in which vital materials travel along pathways called axons inside nerve cells, or neurons. Scientists found that HTT sometimes journeys along these roadways in cellular vehicles (called vesicles) that also carry freight including a protein called Rab4. The research also identified other materials that may be present in these shipments. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 17, 2020 Category: International Medicine & Public Health Source Type: news

Neural vulnerability in Huntington's disease tied to release of mitochondrial RNA
(Picower Institute at MIT) A uniquely comprehensive survey of gene expression by cell type in humans and mice revealed several deficits affecting the most vulnerable neurons in Huntigton's disease. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 17, 2020 Category: International Medicine & Public Health Source Type: news

Roche, Genentech ink real-world data deal with PicnicHealth
The original focus will be on multiple sclerosis but will  extend to include Huntington's disease and hemophilia.   (Source: mobihealthnews)
Source: mobihealthnews - July 16, 2020 Category: Information Technology Source Type: news

Hammer Museum retools its 'Made in L.A.' biennial in the face of COVID-19
The Hammer makes a big pivot on indoor installations for the exhibition, now set for September at the Westwood museum and the Huntington in San Marino. (Source: L.A. Times - Health)
Source: L.A. Times - Health - July 10, 2020 Category: Consumer Health News Authors: Deborah Vankin Source Type: news

Huntington Disease Brain Changes ID'd 24 Years Before Symptoms
WEDNESDAY, July 8, 2020 -- The earliest brain changes due to Huntington disease (HD) can be detected in cerebrospinal fluid (CSF) 24 years before clinical symptoms show, according to a study published in the June 1 issue of The Lancet... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 8, 2020 Category: Pharmaceuticals Source Type: news

Newport to close beaches for July 4 after lifeguard coronavirus infections; Huntington follows suit
Two lifeguards have tested positive, a third is showing symptoms and more than 20 are in quarantine. (Source: L.A. Times - Health)
Source: L.A. Times - Health - July 2, 2020 Category: Consumer Health News Authors: Hillary Davis Source Type: news

Huntington Beach restaurant's no-mask position deeply divides O.C. diners
When Basilico's Pasta e Vino proclaimed its #nomasksallowed stance on social media, some pledged never to patronize the Huntington Beach establishment again. Others supported the viewpoint. (Source: L.A. Times - Health)
Source: L.A. Times - Health - July 1, 2020 Category: Consumer Health News Authors: Sara Cardine Source Type: news

Novel pathology could improve diagnosis and treatment of Huntington ’ s and other diseases
Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington ’ s disease. (Source: University of Bristol news)
Source: University of Bristol news - June 30, 2020 Category: Universities & Medical Training Tags: Health, International, Postgraduate, Publications, Research; Faculty of Biomedical Sciences, School of Physiology, Pharmacology and Neuroscience, Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences, Faculty of Biomedical Science Source Type: news

Novel pathology could improve diagnosis and treatment of Huntington's and other diseases
(University of Bristol) Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease. The article, published in Brain Pathology, describes how SAFB1 expression occurs in both spinocerebellar ataxias and Huntington's disease and may be a common marker of these conditions, which have a similar genetic background. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 30, 2020 Category: International Medicine & Public Health Source Type: news

U.S. Open of Surfing in Huntington Beach is canceled amid COVID-19 pandemic
Organizers have canceled the Vans U.S. Open of Surfing, an annual event near the Huntington Beach for 60 years, because of the COVID-19 pandemic. (Source: L.A. Times - Health)
Source: L.A. Times - Health - June 15, 2020 Category: Consumer Health News Authors: Jack Harris Source Type: news

The Huntington Library to reopen most of its gardens starting July 1
Museum members can visit starting June 17 and the general public on July 1. Museum galleries are expected to re-open in the fall. (Source: L.A. Times - Health)
Source: L.A. Times - Health - June 10, 2020 Category: Consumer Health News Authors: Carolina A. Miranda Source Type: news

Huntington's Disease Biomarkers Appear Years Before Symptoms Huntington's Disease Biomarkers Appear Years Before Symptoms
Early signs of neurodegeneration appeared in young adult carriers of the Huntington's disease gene mutation approximately 24 years before the clinical onset of symptoms, according to a study.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 8, 2020 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Neurobiology of Disease publishes results of AFFiRiS' antibody mAB C6-17 in Huntington's
(MC Services AG) Monoclonal antibody mAB C6-17 targeting human/mutant huntingtin protein (HTT/mutHTT) was developed and characterized. In vitro assay for testing cell-to-cell transmission of mutHTT was established. For the first time, capability of antibody to block mutHTT transmission in vitro was demonstrated. Results support potential of AFFiRiS' antibody-based concept for a new therapeutic targeting circulating extracellular mutHTT. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 3, 2020 Category: Biology Source Type: news

Huntington Beach Pier has reopened in full swing
The city is asking people to keep moving and to be mindful of social distancing. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 28, 2020 Category: Consumer Health News Authors: Matt Szabo Source Type: news

Huntington Beach company profited off fake coronavirus tests, prosecutors say
Wellness Matrix Group falsely promised buyers an FDA-approved coronavirus home testing kit with results in 10 minutes, L.A. city attorney says. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 27, 2020 Category: Consumer Health News Authors: Richard Winton Source Type: news

O.C. company profited off fake coronavirus tests, prosecutors say
A Huntington Beach company falsely promised buyers an FDA-approved coronavirus home testing kit with results in 10 minutes, L.A. city attorney says. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 27, 2020 Category: Consumer Health News Authors: Richard Winton Source Type: news

Research highlights immune molecule's complex role in Huntington's disease
(Picower Institute at MIT) Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice and affects neural connection genes, a new study finds. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 26, 2020 Category: Biology Source Type: news

A natural amino acid could be a novel treatment for polyglutamine diseases
(Osaka University) Researchers from Osaka University, National Center of Neurology and Psychiatry, and Niigata University identified the amino acid arginine as a potential disease-modifying drug for polyglutamine diseases, including familial spinocerebellar ataxia and Huntington disease. Using various mice models of polyglutamine diseases, they showed that arginine prevents polyglutamine protein aggregation, improves motor function and suppresses neurodegeneration of mice. The results of this study could facilitate the clinical use of arginine for polyglutamine diseases that are, to date, incurable. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 25, 2020 Category: Biology Source Type: news

Junior lifeguard programs canceled in Los Angeles County, Seal Beach
Long Beach, Huntington Beach, Newport Beach and San Clemente are still waiting to see whether the program is feasible amid the coronavirus. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 19, 2020 Category: Consumer Health News Authors: Priscella Vega Source Type: news

Israel's Teva gets China approval for Huntington's treatment
Teva Pharmaceutical said on Monday that China has given the go-ahead to its Austedo treatment for Huntington's disease. (Source: Reuters: Health)
Source: Reuters: Health - May 18, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Despite partial reopening of beaches, Huntington Beach presses for injunction on state order
Huntington Beach is pressing ahead for an injunction against Gov. Gavin Newsom's decision last month to close the city's beaches due to the coronavirus. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 12, 2020 Category: Consumer Health News Authors: Matthew Ormseth Source Type: news

Group calls for social distancing, more testing during coronavirus counter-protest in Huntington Beach
Three members of the group Indivisible OC 48 staged an hourlong protest to bring attention to the people who are following Gov. Gavin Newsom's stay-at-home orders during the COVID-19 pandemic. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 9, 2020 Category: Consumer Health News Authors: Matt Szabo Source Type: news

Officials put entire Long Island town on a diet to lower coronavirus risks driven by obesity
Health officials are introducing a voluntary healthy lifestyle and exercise program for the town of Huntington, Long Island, which includes free nutrition advice and fitness classes. (Source: the Mail online | Health)
Source: the Mail online | Health - May 7, 2020 Category: Consumer Health News Source Type: news

Beachgoers rejoice as Orange County's coastline reopens under deal with Newsom
Dana Point, Huntington Beach, Laguna Beach, San Clemente, Newport Beach and Seal Beach allow beach access for active recreation. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 6, 2020 Category: Consumer Health News Authors: Hannah Fry, Priscella Vega, Matt Szabo Source Type: news

Raucous protest in Huntington Beach demands beaches open, end of stay-at-home order
Raucous protest in Huntington Beach demands open beaches, end of stay-at-home order (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 1, 2020 Category: Consumer Health News Authors: Andrew J. Campa, Hannah Fry Source Type: news

Will Orange County enforce Newsom beach closure? Officials vow a fight
Huntington Beach and Dana Point have voted to seek injunctions, and the Orange County sheriff has said he doesn't plan to arrest beachgoers. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 1, 2020 Category: Consumer Health News Authors: Anh Do, Hannah Fry, Richard Winton Source Type: news

Defects in the 'Swiss-army knife' of gene expression may contribute to neuronal diseases like Alzheimer's
(Tohoku University) When the master regulator of protein production malfunctions, it may contribute to the development of neuronal diseases such as Alzheimer's and Huntington's. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 1, 2020 Category: Biology Source Type: news

Huntington Beach mounts legal fight against Newsom closure of O.C. beaches
Coronavirus: Huntington Beach to seek injunction against Newsom closure of O.C. beaches (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 1, 2020 Category: Consumer Health News Authors: Anh Do, Richard Winton Source Type: news

Gov. Newsom may shut down beaches throughout California to slow coronavirus spread
Gov. Gavin Newsom may close beaches to help slow coronavirus spread, a memo to police chiefs says. The announcement is expected Thursday and will affect Newport Beach, Huntington Beach and Laguna Beach. (Source: L.A. Times - Health)
Source: L.A. Times - Health - April 30, 2020 Category: Consumer Health News Authors: Richard Winton, Rosanna Xia, John Myers Source Type: news

Gov. Gavin Newsom may shut down beaches throughout California to slow coronavirus spread
Gov. Gavin Newsom may close beaches to help slow coronavirus spread, a memo to police chiefs says. The announcement is expected Thursday and will affect Newport Beach, Huntington Beach and Laguna Beach. (Source: L.A. Times - Health)
Source: L.A. Times - Health - April 30, 2020 Category: Consumer Health News Authors: Richard Winton, Rosanna Xia, John Myers Source Type: news

The confluence model of sexual aggression: an application with adolescent males - Huntington C, Pearlman DN, Orchowski L.
The Confluence Model of Sexual Aggression is a well-established framework for understanding factors that contribute to men's perpetration of sexual aggression against women, highlighting the roles of hostile masculinity, impersonal sex orientation, and exp... (Source: SafetyLit)
Source: SafetyLit - April 24, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Coronavirus outbreak at Orange County nursing home kills two patients, sickens 72
Two patients from Huntington Valley Healthcare Center died of COVID-19 this week, and 48 other patients and 24 healthcare professionals have tested positive for the coronavirus, according to the company. (Source: L.A. Times - Health)
Source: L.A. Times - Health - April 22, 2020 Category: Consumer Health News Authors: Jaclyn Cosgrove Source Type: news

Protesters slam California stay-at-home orders as 'tyranny.' But truth is more complex
The Huntington Beach protest of coronavirus restrictions comes amid protests elsewhere in the U.S. They don't represent the majority view, polls show. (Source: L.A. Times - Health)
Source: L.A. Times - Health - April 18, 2020 Category: Consumer Health News Authors: Andrew J. Campa, Julia Sclafani Source Type: news