Emory University Fires 2 Neuroscientists Accused of Hiding Chinese Ties
Emory University fired two neuroscientists after they were accused of failing to disclose foreign research funding and connections with China. Li Xiao-Jiang told Science magazine that the university fired him and his wife, Li Shihua––with whom he led a laboratory at the Atlanta university’s medical school. The university also shut down their laboratory. Four Chinese postdoctoral students working in the lab were told to leave the U.S. within 30 days, Li said. Li and his wife are best known for studying Huntington disease. They are denying the allegations and suggested that their firing was part of a proble...
Source: TIME: Science - May 25, 2019 Category: Science Authors: Tara Law Tags: Uncategorized China onetime Research Source Type: news

Most At-Risk Opt Out of Genetic Testing for Huntington Disease
THURSDAY, May 23, 2019 -- The vast majority of people at risk for Huntington disease (HD) choose not to be tested preemptively, mainly because there is no cure for the disease, according to a study published online May 15 in Clinical Genetics. Karen... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 23, 2019 Category: Pharmaceuticals Source Type: news

Why adults at risk for Huntington's choose not to learn if they inherited deadly gene
(Georgetown University Medical Center) As many as 90 percent of individuals who have a parent with Huntington's disease (HD) choose not to take a gene test that reveals if they will also develop the fatal disorder -- and a new study details the reasons why. Understanding the " why " matters as new clinical trials testing therapies for people who haven't yet developed symptoms of Huntington disease requires participants to be tested for the HD gene to be included in the trials. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 16, 2019 Category: International Medicine & Public Health Source Type: news

Mining 25 years of data uncovers a new predictor of age of onset for Huntington disease
(University of British Columbia) Investigators at the University of British Columbia (UBC)/Centre for Molecular Medicine& Therapeutics (CMMT) and BC Children's Hospital have examined more than 25 years of data to reveal new insights into predicting the age of onset for Huntington disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 16, 2019 Category: International Medicine & Public Health Source Type: news

How mutations lead to neurodegenerative disease
(University of Adelaide) Scientists have discovered how mutations in DNA can cause neurodegenerative disease. The discovery is an important step towards better treatment to slow the progression or delay onset in a range of incurable diseases such as Huntington's and motor neurone disease - possibly through the use, in new ways, of existing anti-inflammatory drugs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 13, 2019 Category: International Medicine & Public Health Source Type: news

Nanotubes enable travel of Huntington's protein
(Scripps Research Institute) Nanotube tunnels extend like bridges for the toxic Huntington's disease protein, and spring back after delivery, a new study finds. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 10, 2019 Category: International Medicine & Public Health Source Type: news

LEGATO-HD: Laquinimod Misses Primary Aim in Huntington's LEGATO-HD: Laquinimod Misses Primary Aim in Huntington's
No significant changes on a clinical motor rating scale emerged after 1 year, but researchers report some intriguing differences on brain imaging.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 9, 2019 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Novel Treatment for Huntington's Shows Early Promise Novel Treatment for Huntington's Shows Early Promise
The first-in-human trial of investigational agent RG6042 (aka, HTTRx) provides details about safety and other factors behind its potential in early Huntington's disease.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 9, 2019 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Huntington drug successfully lowers levels of disease-causing protein
(University of British Columbia) An international clinical trial has found that a new drug for Huntington disease is safe, and that treatment with the drug successfully lowers levels of the abnormal protein that causes the debilitating disease in patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 6, 2019 Category: International Medicine & Public Health Source Type: news

When designing clinical trials for huntington's disease, first ask the experts
(IOS Press) Progress in understanding the genetic mutation responsible for Huntington's disease (HD) and at least some molecular underpinnings of the disease has resulted in a new era of clinical testing of potential treatments. How best to design clinical trials in which HD patients are willing to participate and comply is a question faced by researchers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 23, 2019 Category: International Medicine & Public Health Source Type: news

Hope for those with Huntington's – podcast
Robin McKie, the Observer ’s science and environment editor, discusses an innovative drug that may soon offer ways to fight Huntington’s disease, while Mark Newnham describes being diagnosed with the inherited condition. Plus: Peter Beaumont describes his trip to the Costa Rican cloud forest, at threat from climate chang eForMark Newnham and thousands of others who havebeen told they have inherited Huntington ’s disease, the future would appear bleak, a prospect of inexorable physical and mental decline. But scientists believe they areclosing in on a treatment to control its worst effects.Anushka Asthana ...
Source: Guardian Unlimited Science - April 22, 2019 Category: Science Authors: Presented by Anushka Asthana with Robin McKie, Mark Newnham and Peter Beaumont, produced by Amy Walker, Brenna Daldorph, Ammar Kalia, Elizabeth Cassin and Eloise Stevens; executive producers Phil Maynard and Nicole Jackson Tags: Huntington's disease Science Climate change Costa Rica Medical research Source Type: news

Drug used to treat high blood pressure could relieve Parkinson's, Huntington's and Alzheimer's
A study by the University of Cambridge found the hypertension medication felodipine reduced the toxic build-up of proteins in the brains of mice and zebrafish with these diseases. (Source: the Mail online | Health)
Source: the Mail online | Health - April 18, 2019 Category: Consumer Health News Source Type: news

Blood pressure drug shows promise for treating Parkinson's and dementia in animal study
(University of Cambridge) A prescribed drug to treat high blood pressure has shown promise against conditions such as Parkinson's, Huntington's and forms of dementia in studies carried out in mice and zebrafish at the University of Cambridge. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 18, 2019 Category: Biology Source Type: news

EIP Pharma closes financing for new indications for former Vertex drug
EIP Pharma, a central nervous system-focused therapeutics company, announced the successful completion of $11.2 million in new private funding to explore the use of an investigational drug as a treatment for dementia with Lewy bodies and for the cognitive deficits in Huntington's disease. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - April 15, 2019 Category: Pharmaceuticals Source Type: news

Survey Winner Receives $2,000 in Student Health Totes Product
Rejeanne M. Burton Duvall, RN, MSN/Ed of St. Mary’s School of Nursing in Huntington, West Virginia, accepted a survey prize of $2,000 of Pocket Nurse proprietary Student Health Totes. "This prize...(PRWeb April 11, 2019)Read the full story at https://www.prweb.com/releases/survey_winner_receives_2_000_in_student_health_totes_product/prweb16231147.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - April 11, 2019 Category: Pharmaceuticals Source Type: news

Disability Insurer's Denial Of Benefits Was Not Abuse Of Discretion, Judge Says
HUNTINGTON, W.Va. - A disability insurer did not abuse its discretion in denying a long-term disability (LTD) benefits claim because the insurer considered all of the medical evidence and consulted with two physicians before denying the claim, a West Virginia federal judge said March 27 (Genka Popov v. University Physicians& Surgeons Inc. Long Term Disability Plan, et al., No. 18-296, S.D. W.Va., 2019 U.S. Dist. LEXIS 51685). (Source: LexisNexis® Mealey's™ Disability Insurance Legal News)
Source: LexisNexis® Mealey's™ Disability Insurance Legal News - April 9, 2019 Category: Medical Law Source Type: news

Armed mom saves daughter from Muslim kidnapper in shopping mall abduction attempt
(Natural News) A mom armed with a pistol saved her 5-year-old daughter from being kidnapped at a West Virginia mall Monday night. (Article by Adan Salazar republished from Infowars.com) The incident happened in Old Navy at the Huntington Mall in Barboursville around 6PM as Mohamed Fathy Hussein Zayan, 54, from Alexandria, Egypt, “grabbed the child... (Source: NaturalNews.com)
Source: NaturalNews.com - April 3, 2019 Category: Consumer Health News Source Type: news

Abnormalities in a protein affecting how nerve cells change shape
(IOS Press) Amsterdam, NL, April 3, 2019 - Since 1993, when the gene that causes Huntington's disease (HD) was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe progressive neural deterioration. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 3, 2019 Category: International Medicine & Public Health Source Type: news

Fellowship to further international research links in Huntington's disease
(University of Plymouth) Dr. Shouqing Luo, Associate Professor in the University's Institute of Translational and Stratified Medicine, received the Newton Advanced Fellowship from the Royal Society, in partnership with the UK Academy of Medical Sciences and the National Nature Science Foundation of China. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 3, 2019 Category: International Medicine & Public Health Source Type: news

Local Jurisdictions Paying the Price for Nation ’s Opioid Crisis
As the nation's opioid crisis has devastated thousands of families, it also has taken a crippling financial toll on cities, small towns and counties around the country. Packed jails, increased ambulance runs and overworked coroners, sheriff's deputies and public defenders are just some of the consequences of the massive epidemic that has forced localities to divert millions of dollars to overdose-related emergencies and addiction treatments. That cost was acknowledged this week in a settlement between OxyContin maker Purdue Pharma and the state of Oklahoma, a settlement that included $12.5 million for local governments. Bu...
Source: JEMS Patient Care - March 28, 2019 Category: Emergency Medicine Tags: News Patient Care Administration and Leadership Source Type: news

Local Jurisdictions Paying the Price for Nation ’s Opioid Crisis
As the nation's opioid crisis has devastated thousands of families, it also has taken a crippling financial toll on cities, small towns and counties around the country. Packed jails, increased ambulance runs and overworked coroners, sheriff's deputies and public defenders are just some of the consequences of the massive epidemic that has forced localities to divert millions of dollars to overdose-related emergencies and addiction treatments. That cost was acknowledged this week in a settlement between OxyContin maker Purdue Pharma and the state of Oklahoma, a settlement that included $12.5 million for local governments. Bu...
Source: JEMS: Journal of Emergency Medical Services News - March 28, 2019 Category: Emergency Medicine Tags: News Patient Care Administration and Leadership Source Type: news

How nerve cells control misfolded proteins
(Ruhr-University Bochum) Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal. They have identified the so-called Linear Ubiquitin Chain Assembly Complex, Lubac for short, as a crucial player in controlling misfolded proteins in cells. The group is hoping to find a new therapeutic approach to treat neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's chorea, all of which are associated with misfolded proteins. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 27, 2019 Category: Biology Source Type: news

Risk factors for suicidality in Huntington disease: an analysis of the 2CARE clinical trial - McGarry A, McDermott MP, Kieburtz K, Alan Fung WL, McCusker E, Peng J, de Blieck EA, Cudkowicz M.
OBJECTIVE: Most suicidality literature in Huntington disease (HD) is based on natural history studies or retrospective reviews, but reports on risk factors from clinical trials are limited. METHODS: We analyzed 609 participants from 2CARE, a random... (Source: SafetyLit)
Source: SafetyLit - March 11, 2019 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news

At last, hope for families living in the shadow of Huntington ’s disease
An innovative drug may soon offer new ways to fight this cruel inherited conditionMatt Ellison was seven when his father was diagnosed with Huntington ’s disease. The condition – which is progressive, incurable and invariably fatal – took 15 years to kill John Ellison.The impact on Matt ’s life was profound. His father, who had inherited the disease from his mother, found he could no longer concentrate enough to hold down his job as an engineer at Jaguar. Later he began to lose the power of movement and, eventually, lost his ability to speak. At his local school Matt was mocked b ecause of his fathe...
Source: Guardian Unlimited Science - March 3, 2019 Category: Science Authors: Robin McKie Tags: Huntington's disease Medical research Neuroscience Genetics Health UK news Source Type: news

Cognitive fitness to drive in Huntington's disease: assessing the clinical utility of DriveSafe DriveAware - Farrell HJ, Andrews SC, Ryan NP, Davis MC, Gordon S, Stout JC, Fisher F.
BACKGROUND: DriveSafe DriveAware (DSDA) has been validated as an off-road screening tool for predicting on-road driving performance in clinical populations, but its utility in people with Huntington's disease (HD) is unknown. OBJECTIVE: Our aim was... (Source: SafetyLit)
Source: SafetyLit - February 25, 2019 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

85th NHGRI Advisory Council to meet Feb. 11th
The National Advisory Council for Human Genome Research will meet in open session on Monday, February 11th. Dr. Green will present his Director's Report, a summary of the various activities across the Institute and the field of genomics. Geisinger National Precision Health's Director,Huntington Willard, Ph.D., will deliver a presentation on genomics, population health and precision health at Geisinger. NHGRI staff report on updates to the eMERGE Network, Clinical Genome (ClinGen) Resource and more. Live webcast starts at 10 a.m. Eastern. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - February 10, 2019 Category: Genetics & Stem Cells Source Type: news

New Guidelines on Neuropsychiatric Symptoms in Huntington's New Guidelines on Neuropsychiatric Symptoms in Huntington's
New guidelines for the management of agitation, anxiety, apathy, psychosis, and sleep disorders in Huntington's disease patients have been published.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 8, 2019 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Lynn Program Helps New Mothers Struggling With Opioid Addiction
LYNN (CBS) – Recent research shows the opioid epidemic can be especially deadly for new mothers. When it comes to finding help, long-term options are not usually available. A unique program in Lynn is giving moms the kind of help they need. Jessica Cardinal found the help she needed at the Johnson Street residential treatment program. The 24-year-old recovering heroin addict is now slowly rebuilding her life. A mother of two, Jessica says her darkest days are unrecognizable. “It ended with me in a car shooting heroin with my kid in the back. And that, to me, was my rock bottom,” she recalled. “There...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 6, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Lynn Opioid Addiction opioid crisis Source Type: news

CIRM approves $6 million for UCI Researchers to study new treatment for Huntington's disease
(University of California - Irvine) Following a California Institute for Regenerative Medicine (CIRM) Independent Citizens Oversight Committee meeting held last week, University of California, Irvine (UCI) researchers learned they will receive $6 million in funding to support the continued development of a promising new treatment for Huntington's disease (HD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 4, 2019 Category: International Medicine & Public Health Source Type: news

Revolutionary microscopy technique allows scientists to better understand amyloid-based diseases such as Alzheimer's and Parkinson's
(Natural News) A new breed of powerful microscopes has enabled British researchers to make huge strides in the study of amyloid diseases. According to a Science Daily article, cryo-electron microscopes have enabled new discoveries about the proteins that cause Alzheimer’s, Huntington’s, and Parkinson’s diseases. These powerful instruments use electrons to view the shape of the samples.... (Source: NaturalNews.com)
Source: NaturalNews.com - February 3, 2019 Category: Consumer Health News Source Type: news

Expert-based clinical guidelines focus on behavioral symptoms in Huntington's disease
(IOS Press) Although Huntington's disease (HD) is traditionally thought of as a neurological disorder, behavioral symptoms are a common feature and frequently cause distress and difficulty to patients, family members, and other caregivers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 30, 2019 Category: International Medicine & Public Health Source Type: news

Comparable rates of simulator sickness in Huntington's disease and healthy individuals - Jacobs M, van der Zwaan KF, Hart EP, Groeneveld GJ, Roos RAC.
OBJECTIVE Investigating driving competence with a simulator provides a controlled setting and has a high reproducibility. In addition, there is less risk of physical harm compared to on-road tests. A disadvantage of using simulators is the occurrence of s... (Source: SafetyLit)
Source: SafetyLit - January 29, 2019 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Gosport hospital deaths: 'My father’s life was ended by someone else'
David Huntington told BBC Panorama of his anger over his father’s death at the Gosport War Memorial Hospital. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 21, 2019 Category: Consumer Health News Source Type: news

Kettenbach LP Acquires Airway Metrics, LLC
Huntington Beach, CA —January 15, 2019—Management from Kettenbach LP and Airway Metrics LLC announced today the acquisition by Kettenbach LP of all business assets of Airway Metrics effective end of business February 28, 2019.Airway Metrics LLC has provided an effective product system to assist dentists in determining the correct vertical and protrusive dimensions needed in a bite to produce an optimum airway to manage OSA through dental professionally prescribed and delivered oral sleep appliances.Supported by a large number of experts in the field of Dental Sleep Medicine, Airway Metrics has become an essenti...
Source: Dental Technology Blog - January 16, 2019 Category: Dentistry Source Type: news

Sea slug study illuminates how mitochondria move
(Scripps Research Institute) Defects in the transport of cells' energy organelles are a suspected cause of diseases including Alzheimer's, ALS, Huntington's and Parkinson's. A new study reveals the genetics behind mitochondrial shifts. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 16, 2019 Category: International Medicine & Public Health Source Type: news

Speeding up genetic diagnosis of Huntington's disease
(Swiss National Science Foundation (SNSF)) Elongated segments of DNA cause Huntington's disease and certain other disorders of the brain. Researchers funded by the SNSF have developed a method to determine the length of the mutated genes quickly and easily. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 10, 2019 Category: International Medicine & Public Health Source Type: news

Fire chief's approach to opioid crisis has big impact
We're kicking off our new TED Talks partnership with Jan Rader, who's hailed for her efforts in Huntington, West Virginia (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - January 2, 2019 Category: Consumer Health News Source Type: news

Huntington's Antisense Therapy Enters Phase III
(MedPage Today) -- Other ways to halt mutant huntingtin also emerge (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - December 26, 2018 Category: Neurology Source Type: news

Antisense Therapy Shows Promise in Huntington's
(MedPage Today) -- First human trial of huntingtin-lowering drug appears safe, well tolerated (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - December 26, 2018 Category: Neurology Source Type: news

Autophagy and mitochondria: Targets in neurodegenerative disorders
(Bentham Science Publishers) Cellular homeostasis depends on the timely clearance of damaged cellular organelles and proteins via pathways including autophagy. Mitochondria and mitochondrial autophagy play a vital role in cellular health and failure of these pathways can have a devastating effect on cellular homeostasis. Here, the researchers review the involvement of mitochondrial and autophagy dysfunction in neurodegenerative disorders specifically focusing on Alzheimer's, Parkinson's and Huntington's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 26, 2018 Category: International Medicine & Public Health Source Type: news

Pitt-led research describes how neurons could disconnect from each other in Huntington's disease
(University of Pittsburgh Schools of the Health Sciences) Newly described mechanism called 'neuritosis' could play an important role in normal brain development, aging and neurodegenerative disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 24, 2018 Category: International Medicine & Public Health Source Type: news

The brain's support cells show defective development in Huntington's disease
(University of Copenhagen The Faculty of Health and Medical Sciences) The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the brain's support cells, researchers from the University of Copenhagen demonstrate in a new study based on mice trials. The researchers' long-term goal is to be able to use the research results to develop a treatment for Huntington's disease using glial cells. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 21, 2018 Category: Biology Source Type: news

Study Confirms Central Role of Brain ’s Support Cells in Huntington’s, Points to New Therapies
New research gives scientists a clearer picture of what is happening in the brains of people with Huntington ’s disease and lays out a potential path for treatment. The study, which appears today in the journal Cell Stem Cell, shows that support cells in the brain are key contributors to the disease. (Source: University of Rochester Medical Center Press Releases)
Source: University of Rochester Medical Center Press Releases - December 14, 2018 Category: Universities & Medical Training Authors: University of Rochester Medical Center Source Type: news

Gait, balance, and falls in Huntington disease - Vuong K, Canning CG, Menant JC, Loy CT.
Huntington disease (HD) is an autosomal-dominant, progressive, neurodegenerative disorder, characterized by involuntary movements and other motor impairments, cognitive/behavioral symptoms, and psychiatric disorders. Gait and balance impairments and falls ... (Source: SafetyLit)
Source: SafetyLit - December 3, 2018 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Woman who inherited fatal illness to sue doctors in groundbreaking case
Legal action over non-disclosure of father ’s Huntington’s disease could lead to huge changes in patient confidentialityLawyers are bringing a case against a London hospital trust that could trigger major changes to the rules governing patient confidentiality. The case involves a woman who is suing doctors because they failed to tell her about her father ’s fatal hereditary disease before she had her own child.The woman discovered – after giving birth – that her father carried the gene for Huntington’s disease, a degenerative, incurable brain condition. Later she found out she had inheri...
Source: Guardian Unlimited Science - November 25, 2018 Category: Science Authors: Robin McKie Science Editor Tags: Huntington's disease UK news Science Genetics Biology Law Doctors Health Society Source Type: news

C-Path, CHDI and CDISC announce therapeutic area user guide for Huntington's Disease
(Critical Path Institute (C-Path)) The Huntington's Disease Regulatory Science Consortium, launched in March 2018 by the Critical Path Institute and CHDI Foundation, today, along with the Clinical Data Interchange Standards Consortium, announce the open availability of a newly developed Huntington's Disease Therapeutic Area User Guide. The guide has been developed to describe the most broadly utilized clinical concepts for data acquisition and analysis in Huntington's disease clinical studies using the CDISC standard format. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 1, 2018 Category: International Medicine & Public Health Source Type: news

Knocking On Doors To Get Opioid Overdose Survivors Into Treatment
Within days of an OD from opioids or other drugs, users in Huntington, W.Va., are visited by a quick-response team at home, the hospital or in jail. Reversing an OD is just recovery's first step.(Image credit: Sarah McCammon/NPR) (Source: NPR Health and Science)
Source: NPR Health and Science - October 24, 2018 Category: Consumer Health News Authors: Sarah McCammon Source Type: news

Predictors of simulated driving performance in Huntington's disease - Jacobs M, Hart EP, Mejia Miranda Y, Groeneveld GJ, van Gerven JMA, Roos RAC.
BACKGROUND: As the disease progresses, patients with Huntington's disease (HD), an inherited neurodegenerative disorder, become less independent in their daily life activities and have to consider if they can still drive a car. For most patients, the decis... (Source: SafetyLit)
Source: SafetyLit - October 9, 2018 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Penn researchers: Class of neurological disorders share 3D genome folding pattern
(University of Pennsylvania) Researchers at the University of Pennsylvania have found a new common thread linking nearly all of the trinucleotide repeat expansion diseases, which include ALS, Huntington's Disease and Fragile X Syndrome, involving the complicated 3D patterns that the DNA is folded into in order to fit in the nucleus of the cell. Nearly all of the short tandem repeats known to grow unstable in disease are located at the boundaries that separate neighboring folded domains. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 18, 2018 Category: International Medicine & Public Health Source Type: news

Improving Huntington's disease detection
(Source: ScienceNOW)
Source: ScienceNOW - September 13, 2018 Category: Science Authors: Maroso, M. Tags: twis Source Type: news